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1
Thrace Meeting
South Eastern Europe (SEE) Management
Meeting– 10/02/2021
EuFMD
2
Key objective of the South Eastern Europe (SEE) Management Meeting :
• Present progress done in the implementation of EuFMD Phase V workplan for the South
Eastern Europe region during the last six months
• Agree on additional areas of interest where further support is required to improve
emergency preparedness and coordination across the region until the end of the current
biennium (finalizing in September 2021).
3
Meeting Agenda
4
Meeting
Agenda
eufmdvirtual.com
Final Session – 16 February 2021
EuFMD / Open Session
1
Pillar I - Sub-component: 1.4.2.2:
EuFMD SEE member nations - Policy and
Stakeholders networks
Dr Mirzet Sabirovic
EuFMD. European Commission for the Control of Foot-and-Mouth Disease
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
2
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
1st Call Scope
 National Animal Health Policy Areas - FAST diseases (i.e. surveillance, disease control,
vectors, laboratory)
 Launched – end of September 2020
 Deadline for proposals – End of October 2020
1st Call Outputs
 Seven proposals received and assessed - Dec 2020:
Five successful
Two unsuccessful
 Letter of Agreement with successful proposals – Jan 2021
EuFMD SEE member nations - Policy and Stakeholders networks
Objective: 1st EuFMD SEE FAR Call for Proposals - Establishing national networks to connect
veterinary services, laboratories, research institutions and universities
3
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
Successful proposals:
 Have been jointly agreed by a national veterinary competent authority and providers of
research
 A range of stakeholders involved – competent authority, laboratories, science and research
institutions, universities, farmers
 Policy areas for evidence needs covered:
 Vector surveillance (i.e. LSD and other vector borne animal diseases),
 Vaccines - Cellular and humoral response to vaccination and interaction with the colostral immunity in calves (i.e. LSD),
 Improving farm biosecurity for FAST diseases prevention and control,
 Establishing a serum bank for FAST diseases prevention and control.
 Average duration: 6-8 months
EuFMD SEE member nations - Policy and Stakeholders networks
Objective: 1st EuFMD SEE FAR Call for Proposals - Establishing national networks to connect
veterinary services, laboratories, research institutions and universities
4
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
A Guide and a Checklist – Preliminary draft:
 Developed for consultation with EuFMD SEE Management Meeting (February
2021)
 Provides for standardization in engaging national stakeholders’ network
 Sets the platform for:
 Regular use of science and research in policy and decision-making during emergency and non-emergency
time) for FAST diseases contingency and strategic planning and implementation
 A Regional approach in engaging national stakeholders’ network
 Disseminate to EuFMD SEE member nations for feedback (March 2021)
 Prepare a final document for EuFMD SEE MM endorsement (June 2021)
 Lessons learned & Review - organize a workshop with the successful projects (Sept
2021)
EuFMD SEE member nations - Policy and Stakeholders networks
Objective: A Guide and a Checklist- Establishing national networks to connect veterinary
services, laboratories, research institutions and universities
eufmdvirtual.com
10 February 2021
EuFMD SEE Management Meeting
1
SEE management meeting, February 2021
In-country support: Survey on operational
procedures for FAST diseases contingency plans
implementation in SEE – results and next steps
Goran Filipović
European Commission for the Control of Foot-and-Mouth Disease
2
SEE Management meeting, February 2021
6 FAST (FMD, PPR, LSD, SGP, BEF and RVF) diseases –
results:
FMD and LSD - all participating countries have
operational manuals (OM) and SOPs/procedures in
place;
PPR, SGP and RVF – two (EU) countries have OMs
and SOPs in place;
BEF - none of participating countries have OMs or
any other disease specific SOP!
Main survey results – diseases
(response rate 50% );
3
SEE Management meeting, February 2021
Specific guidelines/SOPs most countries are missing for all diseases:
 Post – mortem examination;
 Reporting disease internationally;
 Establishing geographical location of outbreaks (e.g. GPS and/or physical maps);
 Procedures for each available carcasses disposal method;
 Public – private partnership.
Main survey results – SOPs/procedures
Other sources – simulation exercises, missing SOPs:
- disinfection protocol for premises, equipment, vehicles, clothes, products and other;
- Veterinary stations (private) missing their own internal procedures for dealing with crises and animal health
emergencies in order to implement measures effectively;
- No Operational manual for PPR.
4
SEE Management meeting, February 2021
Next steps – proposals for agreement
5
SEE Management meeting, February 2021
 Survey link is still active, just let us know you participated;
 Workplan for specific In-country assistance will be produced;
 We will use simulation exercises to identify other areas where support is needed;
 Except written documents and procedures, we will work on collection, preparation
and sharing of other useful materials for FAST disease emergency preparedness and
training (such as tutorial materials, video, PPTs, documents, forms)
THANK YOU!
Follow up
eufmdvirtual.com
SEE Management Meeting – 10th February 2021
EuFMD / Open Session
1
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
Laboratory preparedness / PTS
Kiril KRSTEVSKI
2
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
Training activities
1. Virtual workshop “Improved FMDV detection and typing using molecular tools”
- 2 half-days event (30 November and 04 December), in collaboration with FMD EU-RL (ANSES)
- 13 participants from 7 national laboratories, with experience in
PCR and sequencing
- Training objectives:
- improved knowledge on referent molecular methods for
FMDV typing
- tools for sequence data analysis
- use of obtained sequence data in the context of improved
disease control
2. Virtual workshop “Laboratory contingency planning”
- Scheduled for 11 – 12 March; calls for nominations will be distributed very soon
- Training objective: improve knowledge on lab contingency planning and contribute to development of LCPs.
3
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
PTS update
- summary of PTS-2020 results
All participating laboratories communicated their results with EURL (only 1 SEE country did not participate)
Support in reagents was beneficial for maintaining and use of various methods (PCR, ELISAs)
1. FMD virus detection methods:
- 9/11 laboratories fully conform – improvement compared to last year (7/11)
2. FMD antibody detection methods:
- 7/11 fully conform (same as last year); problems with interpretation (infected/vaccinated), not with
the testing procedure
- Overall, the results were good, considering the PT was more complex this year
4
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
PTS update - next steps
PT2020 follow up:
- Trainings will be organized in collaboration with EURL, specifically tailored to address the difficulties
faced
- Organization of postponed face-2-face trainings at EURL, if possible this summer
2021 plans:
- survey to assess the needs and provide essential reagents for PTS, where needed (March - June)
- Inclusion of specific PT samples for laboratories which participated in the last years’ v-workshop (to
assess the impact of the ws)
5
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
Diagnostic bank of reagents
6
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
Planned re-stock Planned total
250 1 000
1 000 2 000
Procurement Planned total
5 000 5 500
720 990
720 990
720 990
Kits for FMDV detection
Ag-ELISA (serotyping)
RT-qPCR (+ RNA extraction)
Kits for antibody detection
(serology)
NSP ELISA
SPC ELISA (Serotype O)
SPC ELISA (Serotype A)
SPC ELISA (Serotype Asia-1)
Procurement is in progress
Diagnostic bank – FMD kits: update and plans
Primary storage location – IZSLER,
Brescia
Reagent Bank,
FAO/OIE Lab
7
EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
Planned re-stock Planned total
1000 1 000
1 000 1 000
Kits for FMDV detection
RT-qPCR (+ RNA extraction)
PPR, LSD/SPGP primer/probes
Procurement is in progress
Diagnostic bank – additional PCR reagents and secondary storage location
Additional storage location (PCR only) –
FVMS, Skopje
Reagent Bank,
FAO/OIE Lab
Additional
storage location
• Flexibility to use the “core” PCR reagents for different
diseases (FMD, PPR, LSD/SPGP)
• Back-up solution if difficulties to deliver from the primary
DB location (Brescia)
eufmdvirtual.com
Final Session – 16 February 2021
EuFMD / Open Session

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SEE Management Meeting February 2021

  • 1. 1 Thrace Meeting South Eastern Europe (SEE) Management Meeting– 10/02/2021 EuFMD
  • 2. 2 Key objective of the South Eastern Europe (SEE) Management Meeting : • Present progress done in the implementation of EuFMD Phase V workplan for the South Eastern Europe region during the last six months • Agree on additional areas of interest where further support is required to improve emergency preparedness and coordination across the region until the end of the current biennium (finalizing in September 2021).
  • 5. eufmdvirtual.com Final Session – 16 February 2021 EuFMD / Open Session
  • 6. 1 Pillar I - Sub-component: 1.4.2.2: EuFMD SEE member nations - Policy and Stakeholders networks Dr Mirzet Sabirovic EuFMD. European Commission for the Control of Foot-and-Mouth Disease EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021
  • 7. 2 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 1st Call Scope  National Animal Health Policy Areas - FAST diseases (i.e. surveillance, disease control, vectors, laboratory)  Launched – end of September 2020  Deadline for proposals – End of October 2020 1st Call Outputs  Seven proposals received and assessed - Dec 2020: Five successful Two unsuccessful  Letter of Agreement with successful proposals – Jan 2021 EuFMD SEE member nations - Policy and Stakeholders networks Objective: 1st EuFMD SEE FAR Call for Proposals - Establishing national networks to connect veterinary services, laboratories, research institutions and universities
  • 8. 3 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 Successful proposals:  Have been jointly agreed by a national veterinary competent authority and providers of research  A range of stakeholders involved – competent authority, laboratories, science and research institutions, universities, farmers  Policy areas for evidence needs covered:  Vector surveillance (i.e. LSD and other vector borne animal diseases),  Vaccines - Cellular and humoral response to vaccination and interaction with the colostral immunity in calves (i.e. LSD),  Improving farm biosecurity for FAST diseases prevention and control,  Establishing a serum bank for FAST diseases prevention and control.  Average duration: 6-8 months EuFMD SEE member nations - Policy and Stakeholders networks Objective: 1st EuFMD SEE FAR Call for Proposals - Establishing national networks to connect veterinary services, laboratories, research institutions and universities
  • 9. 4 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 A Guide and a Checklist – Preliminary draft:  Developed for consultation with EuFMD SEE Management Meeting (February 2021)  Provides for standardization in engaging national stakeholders’ network  Sets the platform for:  Regular use of science and research in policy and decision-making during emergency and non-emergency time) for FAST diseases contingency and strategic planning and implementation  A Regional approach in engaging national stakeholders’ network  Disseminate to EuFMD SEE member nations for feedback (March 2021)  Prepare a final document for EuFMD SEE MM endorsement (June 2021)  Lessons learned & Review - organize a workshop with the successful projects (Sept 2021) EuFMD SEE member nations - Policy and Stakeholders networks Objective: A Guide and a Checklist- Establishing national networks to connect veterinary services, laboratories, research institutions and universities
  • 10. eufmdvirtual.com 10 February 2021 EuFMD SEE Management Meeting
  • 11. 1 SEE management meeting, February 2021 In-country support: Survey on operational procedures for FAST diseases contingency plans implementation in SEE – results and next steps Goran Filipović European Commission for the Control of Foot-and-Mouth Disease
  • 12. 2 SEE Management meeting, February 2021 6 FAST (FMD, PPR, LSD, SGP, BEF and RVF) diseases – results: FMD and LSD - all participating countries have operational manuals (OM) and SOPs/procedures in place; PPR, SGP and RVF – two (EU) countries have OMs and SOPs in place; BEF - none of participating countries have OMs or any other disease specific SOP! Main survey results – diseases (response rate 50% );
  • 13. 3 SEE Management meeting, February 2021 Specific guidelines/SOPs most countries are missing for all diseases:  Post – mortem examination;  Reporting disease internationally;  Establishing geographical location of outbreaks (e.g. GPS and/or physical maps);  Procedures for each available carcasses disposal method;  Public – private partnership. Main survey results – SOPs/procedures Other sources – simulation exercises, missing SOPs: - disinfection protocol for premises, equipment, vehicles, clothes, products and other; - Veterinary stations (private) missing their own internal procedures for dealing with crises and animal health emergencies in order to implement measures effectively; - No Operational manual for PPR.
  • 14. 4 SEE Management meeting, February 2021 Next steps – proposals for agreement
  • 15. 5 SEE Management meeting, February 2021  Survey link is still active, just let us know you participated;  Workplan for specific In-country assistance will be produced;  We will use simulation exercises to identify other areas where support is needed;  Except written documents and procedures, we will work on collection, preparation and sharing of other useful materials for FAST disease emergency preparedness and training (such as tutorial materials, video, PPTs, documents, forms) THANK YOU! Follow up
  • 16. eufmdvirtual.com SEE Management Meeting – 10th February 2021 EuFMD / Open Session
  • 17. 1 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 Laboratory preparedness / PTS Kiril KRSTEVSKI
  • 18. 2 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 Training activities 1. Virtual workshop “Improved FMDV detection and typing using molecular tools” - 2 half-days event (30 November and 04 December), in collaboration with FMD EU-RL (ANSES) - 13 participants from 7 national laboratories, with experience in PCR and sequencing - Training objectives: - improved knowledge on referent molecular methods for FMDV typing - tools for sequence data analysis - use of obtained sequence data in the context of improved disease control 2. Virtual workshop “Laboratory contingency planning” - Scheduled for 11 – 12 March; calls for nominations will be distributed very soon - Training objective: improve knowledge on lab contingency planning and contribute to development of LCPs.
  • 19. 3 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 PTS update - summary of PTS-2020 results All participating laboratories communicated their results with EURL (only 1 SEE country did not participate) Support in reagents was beneficial for maintaining and use of various methods (PCR, ELISAs) 1. FMD virus detection methods: - 9/11 laboratories fully conform – improvement compared to last year (7/11) 2. FMD antibody detection methods: - 7/11 fully conform (same as last year); problems with interpretation (infected/vaccinated), not with the testing procedure - Overall, the results were good, considering the PT was more complex this year
  • 20. 4 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 PTS update - next steps PT2020 follow up: - Trainings will be organized in collaboration with EURL, specifically tailored to address the difficulties faced - Organization of postponed face-2-face trainings at EURL, if possible this summer 2021 plans: - survey to assess the needs and provide essential reagents for PTS, where needed (March - June) - Inclusion of specific PT samples for laboratories which participated in the last years’ v-workshop (to assess the impact of the ws)
  • 21. 5 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 Diagnostic bank of reagents
  • 22. 6 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 Planned re-stock Planned total 250 1 000 1 000 2 000 Procurement Planned total 5 000 5 500 720 990 720 990 720 990 Kits for FMDV detection Ag-ELISA (serotyping) RT-qPCR (+ RNA extraction) Kits for antibody detection (serology) NSP ELISA SPC ELISA (Serotype O) SPC ELISA (Serotype A) SPC ELISA (Serotype Asia-1) Procurement is in progress Diagnostic bank – FMD kits: update and plans Primary storage location – IZSLER, Brescia Reagent Bank, FAO/OIE Lab
  • 23. 7 EuFMD SEE Management Meeting - Virtual meeting, 10 February 2021 Planned re-stock Planned total 1000 1 000 1 000 1 000 Kits for FMDV detection RT-qPCR (+ RNA extraction) PPR, LSD/SPGP primer/probes Procurement is in progress Diagnostic bank – additional PCR reagents and secondary storage location Additional storage location (PCR only) – FVMS, Skopje Reagent Bank, FAO/OIE Lab Additional storage location • Flexibility to use the “core” PCR reagents for different diseases (FMD, PPR, LSD/SPGP) • Back-up solution if difficulties to deliver from the primary DB location (Brescia)
  • 24. eufmdvirtual.com Final Session – 16 February 2021 EuFMD / Open Session