The document summarizes the capabilities and services of Resourcing Solutions, a business unit within the clinical research organization Chiltern. Resourcing Solutions specializes in providing qualified clinical research staff on a contract basis. It has over 1,200 staff located across 23 offices in 13 countries. In addition to staffing services, Chiltern also offers functional outsourcing, early phase clinical trials, and regulatory and medical affairs support.

1. Resourcing Solutions General Capabilities March 3, 2009

2. Introductions Brian Tresser Business Development Executive

3. Brian Tresser Business Development Executive Education: Indiana University , Bloomington, IN Bachelor’s, College of Arts and Sciences Professional Experience: 7 years of business development experience in life sciences 10 years experience in recruiting and staffing industry 7 years experience providing software, client, and consultative services Joined Chiltern Resourcing Solutions in 2009

4. Understanding Chiltern

5. Our Values and Beliefs “ Our Mission is to deliver expert, high quality, clinical development services around the world – building trustworthy and lasting relationships, understanding each customer’s special needs and, overall, improving the quality of life.” Respect Flexibility Integrity Dedication Enthusiasm Professional

6. Understanding … Chiltern Global operations 1,200 staff throughout the Americas, Europe, and India 23 offices in 13 countries; HQ located outside London, England Therapeutically experienced ↔ quality minded Founded 27 years ago, one of the oldest global CROs Quality is the reason for our success Strong global management team Team experienced in leading global CROs Management participation and support Financial strength $120MM annual revenue, profitable 10th largest CRO Resourcing Solutions 25% of annual Revenue

7. Chiltern Locations SUMMARY 23 Offices in 14 Countries Staff located in 26 Countries Australia New Zealand Israel Bulgaria Lithuania Croatia Serbia Iceland Malta Norway Brazil Peru Mexico EXPERIENCE South Africa Hungary Romania Slovak Rep. Belgium Switzerland Eire Sweden Austria Netherlands Denmark Finland Canada STAFF India , Mumbai x 2 Czech Rep. , Prague Poland , Warsaw Ukraine , Kiev Russia , St Petersburg UK Slough x 2 Stoke Poges Dundee Edinburgh Germany , Munich Portugal , Lisbon Spain, Madrid Italy , Milan France , Paris USA Bristol, TN Austin, TX Winston Salem, NC Carlsbad, LA Atlanta, GA Wilmington, NC Argentina , Buenos Aires OFFICES ASIA / PACIFIC (36) CEE (68) WESTERN EUROPE (867) AMERICAS (388)

8. Global Clinical Development Conducted studies in 34 countries during the past year Resourcing Solutions Functional Outsourcing, contract, interim or permanent contracts Biometrics Successful business model of providing quality, not quantity Early Phase 30 bed clinical research unit and laboratory services, London, UK 42 bed Clinical Research Unit in Dundee, Scotland Regulatory and Medical Affairs Regulatory, Medical, and Pharmacovigilance Chiltern’s Service Offerings

9. Resourcing Solutions

10. Resourcing Solutions … Core Values To supply appropriate candidates on as many occasions as possible To respond as quickly as possible To maintain flexibility and customization To invest in personal development of all seconded staff To maximize sponsor value Maintain open and effective communications with clients and personnel

11. Resourcing Solutions Resourcing Solutions (RS) is a leading business unit within Chiltern designed to offer a fully integrated, resourcing solution to all of your staffing needs. Resourcing Solutions makes up 25% of Chiltern’s overall business. It is the second largest contributor behind Clinical. Because RS is part of the CRO we truly understand your job requirements, the qualifications and experience your staff need, and we are able to attract strong candidates that typically would not work through a staffing agency.

12. Global Overview

13. Types of Personnel Clinical Trial Administrators Clinical Research Associates Project Managers Clinical Data Managers Clinical Data Coordinators Statisticians Medical Information Senior Management Quality Assurance SAS Programmers Data Entry Staff Research Nurses Medical Writers Regulatory Study Site Co-ordinators Pharmaceutical Physicians Pharmacovigilance Interim Managers

14. Types of Placements Individual placements Teams – project or functional Americas, Europe, and India Client office, Chiltern office, Field based Full time, part time All experience levels Freelancers/Interims Trainee Schemes

15. Providing & Maintaining Resources Staffing fluctuations managed via continuous recruitment, Adapt candidate database, and allocations management Drops in workload managed by reallocation to other groups Extensive recruiting sources utilized on a ongoing basis Customized interviewing, screening & reference inquiry Low staff turnover, trended under 10% over the last 5 years Possibilities of career development and promotion within the group High employee satisfaction, Chiltern has created a great place to work! Flexible work locations: Chiltern office, client site, regional field based

16. RS vs Project No project responsibilities No project management No QC e.g. review of MVRs No Investigator Agreements No review of study timelines, patient recruitment etc No feasibility No calculation of allocation No deliverables – only time Client must assess study progress and quality of work on an ongoing basis Client’s remedy is a new staff member not a re-performance of work RS is responsible for the delivery of a qualified staff member – the client may do with them as they will (within reason!) RS is responsible for negligence

17. Daily Rate Responsibility/Risk Salary & Benefits Central Overheads Direct Overheads Line Management Project Deliverables Illustration of how costs increase as more responsibilities are transferred from Sponsor to Chiltern Insourcing Staff Outsourcing Projects Resource allocation Ring-fenced Hybrid Model for multiple staff Hybrid Model Hybrid Solution

18. Key Differentiators A global CRO, not a staffing agency, with a significant service line comprising a dedicated recruitment team utilising Adapt Permanent employment with access to freelancers also Movement between RS and CRO Dedicated Training and Development Department Support network including HR, IT, dedicated named line manager Focused on minimizing co-employment risks In house operational advice and support available Experienced with projects, supply of individuals, teams and FSP relationships Flexible with regards staffing, location and model

19. Managing Co-Employment Risks Chiltern fully employs staff (full benefits) Chiltern RS Line Mgt conducts all HR/employment related interaction & communication Sponsor meetings, not interviews Our MSA indemnification is written to protect sponsor Employee’s sign employer acknowledgement form Freelancer agreement contains language detailing independent contractor relationship

20. Summary Chiltern working in partnership with clients to support hiring of contract staff. Clients involved in team selection and approval Ability to quickly provide strong team or individuals Consideration given to practical challenges such as recruitment, location, training, infrastructure Flexible, customized, open approach to ensure a long term partnership.

21. Thank You