27. /f]6f efO/;af6 x'g] kvfnf /f]syfdsf] nflu
/f]6f efO/; vf]k (Rotavirus Vaccine) z'?jft ug{
tflnd tyf sfo{;~rfng lgb]{lzsf – @)%
25
efu
^
vf]k kZrft x'g ;Sg]
cjfl~5t 36gf(AEFI)
kl/efiff
vf]k nufPkl5 x'g] s'g} klg :jf:Yo ;DalGw cjfl~5t 36gf (AEFI – Adverse Event Following
Immunizaton) h'g vf]k k|of]usf] sf/0faf6 gePsf] klg x'g ;S5 . o:tf cjfl~5t 36gfx¿ vf]k
nufPkl5 ck|Toflzt lrGx, nIf0f, c;fdfGo k|of]uzfnf kl/0ffd jf /f]usf] ?kdf b]vfkb{5g .
P=O{=Pkm=cfO{= sf k|sf/x¿
k|sf/ kl/efiff
vf]ksf] pTkfbg ;+u
;DalGwt k|ltlqmof
(Vaccine Product-
Related Reaction)
vf]kdf lglxt s]xL tTjx¿sf] sf/0fn] x'g;Sg] k|ltlqmof . h:t}–
PgfkmfO{n]lS;; .
An AEFI that is caused or precipitated by a vaccine due to one
or more of the inherent properties of the vaccine product.
vf]ksf] u'0f:t/ ;+u
;Dalwt k|lts[of
(Vaccine quality
defect-related
reaction)
vf]ksf] u'0f:t/Lotfdf x'g] sdLsf sf/0f jf vf]k lbg k|of]u ul/g]
;fdu|Lsf]v/faLsf sf/0f x'g]k|lts[of .
An AEFI that is caused or precipitated by a vaccine that is due
to one or more quality defects of the vaccine product including
its administration device as provided by the manufacturer.
sfo{qmd ;~rfngsf]
qmddf x'g;Sg]q'6L
;+u ;DalGwt k|lts[of
(Immunization
error- related
reaction)
vf]k lbg]qmddf vf]k e08f/0f ubf{, vf]k 3f]Nbf, ;O{ lbFbf x'g;Sg]
q'6Lsf sf/0faf6 x'g;Sg]q'6L .
h:t}– ;'O{ lbPsf]7fFpdf lkk hDg',
An AEFI that is caused by inappropriate vaccine handling, pre-
scribing or administration and thus by its nature is preventable.
Example:Transmission of infection by contaminated multidose
vial.
35. /f]6f efO/;af6 x'g] kvfnf /f]syfdsf] nflu
/f]6f efO/; vf]k (Rotavirus Vaccine) z'?jft ug{
tflnd tyf sfo{;~rfng lgb]{lzsf – @)%
33
/f]6f efO/; vf]k;“u ;DalGwt
;fwf/0ftof ;f]lwg] k|Zgx¿ M
-:jf:Yo sdL{x¿sf] nflu_
k|Zg ! M /f]6f efO/; s] xf]
pQ/ M /f]6f efO/; dfG5] df !(# df la;xk / pgsf ;fyLx¿n] severe gastroenteritis ePsf]
aRrfsf] duodenal mucosa af6 afo]K;L ubf{ kQf nufPsf lyP . of]Reoviridae kl/jf/sf] double-
stranded RNA virus xf] . /f]6f efO/; Ps cToGt ;+qmfds efO/; xf] . o;n] aRrfx¿df lg/Gt/
emf8fkvfnf u/fFp5 . h;n] ubf{ aRrfx¿nfO{ c:ktfndf egf{ u/fpg' kg]{ b]lv d[To;Dd x'g ;Sg]
cj:yf l;h{gf u/fFp5 . Rotaviruses most commonly are classified according to group and
serotype. Seven groups of rotavirus have been described (A–G), and are based on genetic
and antigenic differences in the VP6 protein. Only those viruses in groups A, B, and C are
known to cause disease in humans. Group A rotaviruses are the principal cause of human
disease but Group B rotaviruses have been associated with epidemic gastroenteritis in Asia,
and group C rotaviruses have been associated with sporadic mild gastroenteritis.
lrq g+ % M /f]6f efO/;
k|Zg @ M /f]6f efO/;n] ug]{ emf8fkvfnfsf nIf0fx? s:tf x'G5g
pQ/ M /f]6f efO/; emf8fkvfnf ljleGg k|s[ltsf] x'g] ub{5g . tf/Gtf/ kftnf] lbzf b]lv ulDe/
k|s[ltsf] emf8f kvfnf ;fy} lg/Gt/ jfGtf x'g] ub{5 . olb ;dod} pkrf/ gkfPdf aRrfx¿df
hnljof]hg, zl//df nj0fsf] dfqfdf c;Gt'ng, emGemgfx6sf ;fy} d[To;Dd x'g] ub{5 .
o;sf] z'?jftL cj:yfdf ulDe/ lsl;dsf] kvfnf ! b]lv # lbg;Dd b]lvg] ub{5 h'g cjwLdf Hj/f]
cfpg], kvfnf nfUg], jfGtf x'g],k]6 b'Vg] cfbL h:tf lrGx tyf nIf0fx¿ b]lvG5g . # b]lv lbgdf
of] cj:yf cfkm} /f]lsg klg ;S5 .