Hospital-acquired infections are a major issue worldwide, causing thousands of deaths each year. Health service providers like doctors, nurses, and other staff can play an important role in reducing HAI-related mortality and morbidity. Their roles include following appropriate infection prevention practices, implementing sterilization and disinfection guidelines, monitoring for infections, and notifying others of infected patients. Adhering to their assigned responsibilities regarding patient care, cleaning, laundry, food service, and waste disposal can help combat the spread of infections in healthcare facilities.