One of the most brilliant researchers of all time Dr. Amarjit Mishra, Ex-Assistant Professor of Auburn University has been working on identifying the various metabolic sensors that can be used for therapeutic purposes for asthma patients.
Research by Dr Amarjit Mishra – Disease-modifying therapies for Allergic Asthma Targeting Metabolic Sensors.
1. RESEARCH BY DR AMARJIT MISHRA – DISEASE-
MODIFYING THERAPIES FOR ALLERGIC ASTHMA:
TARGETING METABOLIC SENSORS
By targeting the inflammatory response
through various disease-modifying therapies,
asthma management strategies can be
developed to control symptoms and reduce the
risk of asthma exacerbations. One of the most
brilliant researchers of all time Dr. Amarjit
Mishra, Ex-Assistant Professor of Auburn
University has been working on identifying the
various metabolic sensors that can be used for
therapeutic purposes for asthma patients.
2. VARIOUS METABOLIC
SENSORS
Some disease-modifying therapies have
been identified for allergic asthma.
Firstly, allergen immunotherapy, also
known as allergy shots, is a disease-
modifying therapy for allergic asthma. It
involves regular injections of small
amounts of the allergen over a period of
several months or years.
3. Scientists such as Dr. Amarjit Mishra, Ex-Assistant Professor, Auburn University,
have found that disease-modifying medicines for allergic asthma attempt to change
the disease’s underlying processes and enhance asthma management. Further
research is being conducted to discover the many metabolic sensors that might be
targeted to build effective medicines for treating asthma,
4. Changes in energy metabolism in asthmatic
lungs, for example, resulting in activation of
the leukotriene synthesis pathway or higher
consumption of L-arginine as a substrate, are
frequently addressed by adopting various
treatment tactics to restore equilibrium.
Various phenotypes of asthma are controlled
differently through diverse metabolic
pathways, with glycolysis mediators such as
HIF1a and PKM2 controlling not just DC and
T-cell effector activity in type 2 high asthma,
5. SOME OF THE MOST NOTABLE
METABOLIC
In conclusion, targeting metabolic sensors is a
new area of study in the field of allergic
asthma, as identified by prominent scientists
including Dr. Mishra, Yuanyuan Wu, Wei Li,
and Yifan Hu. According to various
experimental studies conducted in animal
models of allergic asthma, activation of
AMPK, SIRT1, and PPAR-γ has shown
promise in decreasing inflammation and
improving lung function.
Source:- https://resistancephl.com/research-by-dr-amarjit-mishra-disease-modifying-therapies-for-allergic-asthma-targeting-metabolic-sensors/