Mechanisms Mediating Pediatric Severe Asthma and Potential Novel Therapies- Dr Amarjit Mishra.
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According to Amarjit Mishra, in some cases of severe asthma. There is chronic inflammation and repeated episodes of bronchoconstriction which leads to structural changes in the airway tissues
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This document provides information on bronchial asthma, including:
- Asthma is a chronic inflammatory airway disease characterized by wheezing, breathlessness, and coughing.
- It affects over 350 million people globally and causes nearly 400,000 deaths per year, most in developing countries.
- Long-term treatment involves inhaled corticosteroids to reduce inflammation. Other treatments include oral corticosteroids, leukotriene modifiers, and long-acting beta-2 agonists.
- Triggers include infections, allergens, exercise, air pollution, weather changes, drugs, stress, and smoking. Proper management is needed to prevent complications and control symptoms.
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- It affects over 350 million people globally and causes nearly 400,000 deaths per year, most in developing countries.
- Long-term treatment involves inhaled corticosteroids to reduce inflammation. Other treatments include oral corticosteroids, leukotriene modifiers, and long-acting beta-2 agonists.
- Triggers include infections, allergens, exercise, air pollution, weather changes, drugs, stress, and smoking. Proper management is needed to prevent complications and control symptoms.
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The Comprehensiveness of Homoeopathy in Bronchial Asthma
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World asthma day
As the world faces from Covid pandemic it's high time we should take care of our patients suffering from respiratory issues.
On the occasion of World Asthma Day I humbly present you this educational video. I focussed on what realy asthma is,current research in India,use of Artificial Intelligence in the field of Asthma.Most importantly,
I addressed myths about Asthma and shown the true pictures.
Your queries are always welcome.
I hope this video will help lot of Asthma patients and their dear ones who are taking care of them.
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This document discusses refractory asthma, defining it as asthma that remains difficult to control despite extensive evaluation and management over at least 6 months. It outlines the major and minor criteria used to define refractory asthma according to the American Thoracic Society. It also discusses the epidemiology, pathophysiology, clinical presentation, risk factors, diagnostic workup, and management approaches for refractory asthma. Management involves high-dose inhaled corticosteroids and additional controller medications, along with addressing comorbidities and adherence issues. Immunomodulators may be considered for patients with uncontrolled asthma despite optimal conventional treatment.
International Journal of Pharmaceutical Science Invention (IJPSI)
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*Corresponding Author: Amarjit Mishra, Assistant Professor (Former), Laboratory of Lung Inflammation, Department of Pathobiology,
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- 1. They may also require frequent use of rescue medications, such as short-acting bronchodilators, and may have recurrent asthma exacerbations or attacks. That require emergency medical care.
- 2. THE MECHANISM BEHIND PEDIATRIC SEVERE ASTHMA According to Amarjit Mishra, in some cases of severe asthma. There is chronic inflammation and repeated episodes of bronchoconstriction which leads to structural changes in the airway tissues, such as thickening of the airway walls and hypertrophy of smooth muscle cells.
- 3. As oral corticosteroids, biologic agents, or other advanced treatment options, to achieve optimal asthma control. Due to the sensitivity of the disease and vulnerability of young children, the management of pediatric severe asthma typically requires close monitoring
- 4. POTENTIAL NOVEL THERAPIES As Janus kinase (JAK) or phosphodiesterase-4 (PDE-4) are being studied for their potential to reduce inflammation and improve asthma control. Amarjit Mishra Auburn University, being an expert in pulmonology holds a view. That these inhibitors can also be used as potential targets for the treatment of severe asthma.
- 5. It is important to note that these potential novel therapies are still being investigated in clinical trials and are not yet. Widely available for routine clinical use in pediatric severe asthma. Further research is conducted by great scientists such. As Amarjit Mishra to determine their safety, efficacy, and long-term effects of such therapy options. Source:- https://www.cofimagazine.com/5155/education/mechanisms-mediating-pediatric-severe-asthma-and-potential-novel-therapies-dr-amarjit-mishra/