Environmental Exposures and Asthma Development Autophagy, Mitophagy and Cellular Senescence. Explained by Dr. Amarjit Mishra Auburn University.pptx
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Many scientists, including Dr. Amarjit Mishra an Ex-professor, Auburn University in the United States, had worked to understand the pathogenesis of asthma, particularly allergy-induced asthma because it is crucial to understand the underlying mechanism that connects these environmental causes to the development of asthma.
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The Bronchial Asthma is one of the common chronic disorders of respiratory system. The Individual of all age group can be suffering by this respiratory system disorder. Most often the asthma is disease which is related with the symptoms like difficulty in breathing and cough. Wheezing sound heard while the auscultation of chest. Though the bronchial asthma is critical condition it can be treated with the perfect treatment. The knowledge of respiratory tract disorder like bronchial asthma is Important for community. The people should know what is Bronchial asthma, How it progresses, How to avoid critical attack. 11 On the basis of the concept of persistent airway inflammation, two important principles are there. First, the complaint is chronic, frequently life long second, its severity fluctuates and sometimes there may be prolonged remissions. According to WHO Asthma affected an estimated 262 million people in 2019 worldwide and it caused around 4, 55,000 deaths. The Global Asthma Report 2022, by Global Asthma Network, shows that about 35 million Indian people suffer from asthma in 2022. 11 The bronchial asthma need to be treated by Homoeopathic medicines. Homoeopathic medicines produce similar symptoms after administration of it in the healthy human beings. Some of Homoeopathic medicines can help to relive symptoms of acute attack of asthma. This can also help to prevent the recurrence of asthma. According to Dr. Hahnemann asthma is true chronic disease which is because of Miasm. Sometimes symptoms of asthma may alternate with skin symptoms. 12 Homoeopathic treatment is Important to avoid unnecessary adverse effects of modern medicine. Dr. Jayshree Rathva | Pandya Santosh Kumar Jashvantbhai | Parmar Ketulkumar Dilipbhai "The Comprehensiveness of Homoeopathy in Bronchial Asthma" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-6 , December 2023, URL: https://www.ijtsrd.com/papers/ijtsrd60153.pdf Paper Url: https://www.ijtsrd.com/medicine/other/60153/the-comprehensiveness-of-homoeopathy-in-bronchial-asthma/dr-jayshree-rathva
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This document provides an overview of asthma pathophysiology. It defines asthma as a chronic inflammatory disease of the airways characterized by variable periodic symptoms, air flow obstruction, and bronchial hyperresponsiveness. It outlines the main types of asthma as occupational, drug-induced, allergic, and adult-onset. The etiology section notes that asthma causes are unclear but involve genetic and environmental factors like exposure to allergens. The document then lists headings for pathogenesis, signs and symptoms, complications, diagnosis, and plan of treatment but does not provide details on these topics.
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This document provides an overview of asthma, including its definition, types, pathophysiology, clinical manifestations, diagnostic evaluations, and management. Asthma is a chronic inflammatory disease of the airways characterized by wheezing, breathlessness, chest tightness, and cough. It is caused by a combination of genetic and environmental factors and can be triggered by allergens, infections, pollutants, and other irritants. Diagnosis involves assessing symptoms, performing pulmonary function tests, and ruling out other conditions. Treatment focuses on reducing inflammation and controlling symptoms.
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Asthma is a chronic inflammatory disease of the airways characterized by recurrent episodes of wheezing, breathlessness, chest tightness and coughing. It affects approximately 300 million people worldwide. The document discusses the definition, epidemiology, risk factors, clinical manifestations, diagnosis and management of childhood asthma. Genetic and environmental factors such as viral infections, allergens and air pollution are known to trigger asthma symptoms.
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The 11-year-old patient is suffering from an asthma attack likely caused by an allergic reaction to cat dander. His symptoms of wheezing and shortness of breath are worsened by exercise and exposure to allergens. Asthma results from an inflammatory response in the airways to allergens that causes constriction and increased mucus production. Ethnic minorities like the patient have a higher risk of developing asthma due to socioeconomic factors that increase exposure to allergens. The cardiovascular and respiratory systems work closely together, so impairment of one system affects the other as well.
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This document provides an overview of asthma including its definition, epidemiology, etiology, pathophysiology, clinical manifestations, investigations, and management. It defines asthma as a chronic inflammatory lung disease characterized by variable and recurring symptoms of wheezing, breathlessness, chest tightness, and coughing. Key points include that over 334 million people worldwide currently suffer from asthma, environmental factors like allergens and infections contribute to its development, and treatment involves management of symptoms and inflammation.
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1. Pulmonary aspergillosis refers to a spectrum of lung diseases caused by the fungus Aspergillus, including invasive aspergillosis, aspergilloma, and allergic bronchopulmonary aspergillosis.
2. Invasive pulmonary aspergillosis is a severe infection seen in severely immunocompromised patients, critically ill patients, and those with chronic lung diseases like COPD. Chronic necrotizing aspergillosis is a locally invasive infection seen in patients with mild immunosuppression or lung disease.
3. Aspergilloma is a fungus ball that develops in a pre-existing lung cavity, often caused by conditions like
ASTHMA
Bronchial asthma is a chronic inflammatory disorder of the airways that causes recurrent episodes of wheezing, breathlessness, chest tightness and coughing. These episodes are usually associated with widespread but variable airflow obstruction that is often reversible with treatment. Asthma is characterized by airway inflammation, airway hyperresponsiveness, and reversible airway obstruction. Common triggers include allergens, infections, exercise, and environmental factors. Diagnosis involves assessing symptoms, performing pulmonary function tests to check for reversibility of airway obstruction, and ruling out other conditions.
World asthma day
As the world faces from Covid pandemic it's high time we should take care of our patients suffering from respiratory issues.
On the occasion of World Asthma Day I humbly present you this educational video. I focussed on what realy asthma is,current research in India,use of Artificial Intelligence in the field of Asthma.Most importantly,
I addressed myths about Asthma and shown the true pictures.
Your queries are always welcome.
I hope this video will help lot of Asthma patients and their dear ones who are taking care of them.
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Dr.Amarjit Mishra -Unraveling the Lung Immunometabolic Pathways in Airway.Amarjit Mishra Assistant Professor at Auburn University
Amarjit Mishra*
Assistant Professor (Former), Laboratory of Lung Inflammation, Department of Pathobiology, College of Veterinary Medicine, Auburn
University, Auburn, Alabama, United States
*Corresponding Author: Amarjit Mishra, Assistant Professor (Former), Laboratory of Lung Inflammation, Department of Pathobiology,
College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States.
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This document provides an overview of asthma, including its definition, types, pathophysiology, clinical manifestations, diagnostic evaluations, and management. Asthma is a chronic inflammatory disease of the airways characterized by wheezing, breathlessness, chest tightness, and cough. It is caused by a combination of genetic and environmental factors and can be triggered by allergens, infections, pollutants, and other irritants. Diagnosis involves assessing symptoms, performing pulmonary function tests, and ruling out other conditions. Treatment focuses on reducing inflammation and controlling symptoms.
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Asthma is a chronic inflammatory disease of the airways characterized by recurrent episodes of wheezing, breathlessness, chest tightness and coughing. It affects approximately 300 million people worldwide. The document discusses the definition, epidemiology, risk factors, clinical manifestations, diagnosis and management of childhood asthma. Genetic and environmental factors such as viral infections, allergens and air pollution are known to trigger asthma symptoms.
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Smoking is strongly linked to worse asthma outcomes. Exposure to secondhand smoke can cause or exacerbate asthma in both children and adults. Smoking cigarettes leads to higher levels of nicotine and chemicals in the smoke, increasing health risks. The evidence that secondhand smoke causes cancer and other diseases in nonsmokers is conclusive according to leading health organizations.
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World Asthma Day is observed annually on May 2nd to raise awareness about asthma and promote better treatment worldwide. This year's theme is "Asthma Care for All". The Global Initiative for Asthma established World Asthma Day in 1998 to educate people about asthma and support advocacy efforts. Common activities held on this day include educational seminars, asthma screenings, and fundraising events. The goal is to improve asthma management and care globally.
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Asthma is a lung condition that makes the primary airways—known as the bronchi—in the lungs swollen and inflamed all of the time. People who have asthma are more sensitive than other people to things inhaled from the environment, known as triggers.
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The 11-year-old patient is suffering from an asthma attack likely caused by an allergic reaction to cat dander. His symptoms of wheezing and shortness of breath are worsened by exercise and exposure to allergens. Asthma results from an inflammatory response in the airways to allergens that causes constriction and increased mucus production. Ethnic minorities like the patient have a higher risk of developing asthma due to socioeconomic factors that increase exposure to allergens. The cardiovascular and respiratory systems work closely together, so impairment of one system affects the other as well.
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This document provides an overview of asthma including its definition, epidemiology, etiology, pathophysiology, clinical manifestations, investigations, and management. It defines asthma as a chronic inflammatory lung disease characterized by variable and recurring symptoms of wheezing, breathlessness, chest tightness, and coughing. Key points include that over 334 million people worldwide currently suffer from asthma, environmental factors like allergens and infections contribute to its development, and treatment involves management of symptoms and inflammation.
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1. Pulmonary aspergillosis refers to a spectrum of lung diseases caused by the fungus Aspergillus, including invasive aspergillosis, aspergilloma, and allergic bronchopulmonary aspergillosis.
2. Invasive pulmonary aspergillosis is a severe infection seen in severely immunocompromised patients, critically ill patients, and those with chronic lung diseases like COPD. Chronic necrotizing aspergillosis is a locally invasive infection seen in patients with mild immunosuppression or lung disease.
3. Aspergilloma is a fungus ball that develops in a pre-existing lung cavity, often caused by conditions like
ASTHMA
Bronchial asthma is a chronic inflammatory disorder of the airways that causes recurrent episodes of wheezing, breathlessness, chest tightness and coughing. These episodes are usually associated with widespread but variable airflow obstruction that is often reversible with treatment. Asthma is characterized by airway inflammation, airway hyperresponsiveness, and reversible airway obstruction. Common triggers include allergens, infections, exercise, and environmental factors. Diagnosis involves assessing symptoms, performing pulmonary function tests to check for reversibility of airway obstruction, and ruling out other conditions.
World asthma day
As the world faces from Covid pandemic it's high time we should take care of our patients suffering from respiratory issues.
On the occasion of World Asthma Day I humbly present you this educational video. I focussed on what realy asthma is,current research in India,use of Artificial Intelligence in the field of Asthma.Most importantly,
I addressed myths about Asthma and shown the true pictures.
Your queries are always welcome.
I hope this video will help lot of Asthma patients and their dear ones who are taking care of them.
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Amarjit Mishra*
Assistant Professor (Former), Laboratory of Lung Inflammation, Department of Pathobiology, College of Veterinary Medicine, Auburn
University, Auburn, Alabama, United States
*Corresponding Author: Amarjit Mishra, Assistant Professor (Former), Laboratory of Lung Inflammation, Department of Pathobiology,
College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States.
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- 1. ENVIRONMENTAL EXPOSURES AND ASTHMA DEVELOPMENT: AUTOPHAGY, MITOPHAGY AND CELLULAR SENESCENCE. EXPLAINED BY DR. AMARJIT MISHRA AUBURN UNIVERSITY Asthma onset and aggravation are both significantly influenced by environmental exposures. Wheezing, coughing, shortness of breath, and chest tightness can all be symptoms of the chronic respiratory condition known as asthma, which is characterized by inflammation of the airways.
- 2. Many scientists, including Dr. Amarjit Mishra an Ex-professor, Auburn University in the United States, had worked to understand the pathogenesis of asthma, particularly allergy-induced asthma because it is crucial to understand the underlying mechanism that connects these environmental causes to the development of asthma.
- 3. Dr. Amarjit Mishra Ex-professor Auburn University and one of the most renowned pulmonology experts, is committed to comprehending the less well- known causes and processes of the pulmonary pathways.
- 4. Autophagy may be involved in the pathophysiology of allergic asthma, according to recent investigations, notably those of Dr.Amarjit Mishra. Autophagy has been found to have an impact on the growth and operation of immune cells engaged in allergic inflammation, among other components of the immune response.
- 5. The immune cells can produce ROS, which can damage mitochondrial DNA and impair mitochondrial function. This, in turn, can lead to impaired mitophagy and the accumulation of damaged mitochondria in airway epithelial cells. Source:- https://tajahindinews.in/education/environmental-exposures-and-asthma-development-autophagy-mitophagy-and-cellular-senescence-explained-by-dr- amarjit-mishra-auburn-university/