As we know that respiratory diseases are few of the major causes of illness and death in contemporary times, the work by Amarjit Mishra Auburn University.
Amarjit Mishra’s participation in various significant pulmonology initiatives has earned him the reputation of being an accomplished researcher. Throughout his distinguished career as a gifted educator and researcher, Amarjit Mishra has occupied a variety of positions of authority.
Amarjit Mishra of Auburn University has also researched on innovative pharmacological targeting of Th1/Th2/Th17 lung immune pathways in addition to this study on understanding lung immune pathways.
Many scientists, including Dr. Amarjit Mishra an Ex-professor, Auburn University in the United States, had worked to understand the pathogenesis of asthma, particularly allergy-induced asthma because it is crucial to understand the underlying mechanism that connects these environmental causes to the development of asthma.
Model organisms are used in research for several reasons. They are easy to maintain in a laboratory, have short lifecycles, and produce large numbers of offspring. This allows researchers to study biological processes more quickly and with larger sample sizes than using human subjects. Model organisms also have fewer restrictions around their use in experiments than human subjects. While model organisms have limitations and human subjects are still necessary for some types of research, model organisms have significantly advanced our understanding of fundamental biological processes and diseases.
Applicability of mouse models to the study of human disease.pdfcarolinamurua1
Mice and humans share many genetic and physiological similarities but also have important differences that must be considered when using mouse models to study human disease. While mice and humans have a high degree of genetic similarity, their regulatory networks diverge significantly, especially regarding the immune system, metabolism, and stress responses. Physiologically, mice have higher metabolic rates, smaller organs and tissues, and differences in lung anatomy compared to humans. Immunologically, mice and humans differ in leukocyte proportions, T cell activation pathways, antibody subtypes, and responses to pathogens. A thorough understanding of these similarities and differences is necessary for meaningful interpretation and translation of mouse model experiments to human clinical applications.
Asu scientist selected as 2014 recipient of lifetime achievement awardMaysen Abdelkader
Roy Curtiss III, a scientist at the Biodesign Institute at Arizona State University, has been selected as the 2014 recipient of the Lifetime Achievement Award from the American Society for Microbiology. Curtiss was a pioneer in developing safe E. coli strains for gene cloning and has uncovered novel aspects of bacterial pathogenesis. He has also developed attenuated Salmonella-based vaccines that are effective against many human pathogens. Throughout his career, Curtiss has focused on developing vaccines to prevent infectious diseases like pneumonia, tuberculosis, plague, and influenza. Despite his many accomplishments, Curtiss continues his research, striving to develop new vaccines and therapies for diseases.
UCSD undergraduate researchers are studying various ecosystems and their components in order to better understand their functioning and identify factors crucial for preservation. Studies described include examining the role of the Wnt signaling pathway in mammary gland and stem cell development, investigating how the antibiotic salinomycin affects cancer stem cells, and exploring the foraging behavior of bees and life histories of cacti. The goal is to gain insights that can inform effective conservation strategies to protect interdependent living things and environments.
Amarjit Mishra is a seasoned researcher who has devoted the majority of his life to study for the benefit of society. He had been employed as an assistant professor at Auburn University.
Amarjit Mishra’s participation in various significant pulmonology initiatives has earned him the reputation of being an accomplished researcher. Throughout his distinguished career as a gifted educator and researcher, Amarjit Mishra has occupied a variety of positions of authority.
Amarjit Mishra of Auburn University has also researched on innovative pharmacological targeting of Th1/Th2/Th17 lung immune pathways in addition to this study on understanding lung immune pathways.
Many scientists, including Dr. Amarjit Mishra an Ex-professor, Auburn University in the United States, had worked to understand the pathogenesis of asthma, particularly allergy-induced asthma because it is crucial to understand the underlying mechanism that connects these environmental causes to the development of asthma.
Model organisms are used in research for several reasons. They are easy to maintain in a laboratory, have short lifecycles, and produce large numbers of offspring. This allows researchers to study biological processes more quickly and with larger sample sizes than using human subjects. Model organisms also have fewer restrictions around their use in experiments than human subjects. While model organisms have limitations and human subjects are still necessary for some types of research, model organisms have significantly advanced our understanding of fundamental biological processes and diseases.
Applicability of mouse models to the study of human disease.pdfcarolinamurua1
Mice and humans share many genetic and physiological similarities but also have important differences that must be considered when using mouse models to study human disease. While mice and humans have a high degree of genetic similarity, their regulatory networks diverge significantly, especially regarding the immune system, metabolism, and stress responses. Physiologically, mice have higher metabolic rates, smaller organs and tissues, and differences in lung anatomy compared to humans. Immunologically, mice and humans differ in leukocyte proportions, T cell activation pathways, antibody subtypes, and responses to pathogens. A thorough understanding of these similarities and differences is necessary for meaningful interpretation and translation of mouse model experiments to human clinical applications.
Asu scientist selected as 2014 recipient of lifetime achievement awardMaysen Abdelkader
Roy Curtiss III, a scientist at the Biodesign Institute at Arizona State University, has been selected as the 2014 recipient of the Lifetime Achievement Award from the American Society for Microbiology. Curtiss was a pioneer in developing safe E. coli strains for gene cloning and has uncovered novel aspects of bacterial pathogenesis. He has also developed attenuated Salmonella-based vaccines that are effective against many human pathogens. Throughout his career, Curtiss has focused on developing vaccines to prevent infectious diseases like pneumonia, tuberculosis, plague, and influenza. Despite his many accomplishments, Curtiss continues his research, striving to develop new vaccines and therapies for diseases.
UCSD undergraduate researchers are studying various ecosystems and their components in order to better understand their functioning and identify factors crucial for preservation. Studies described include examining the role of the Wnt signaling pathway in mammary gland and stem cell development, investigating how the antibiotic salinomycin affects cancer stem cells, and exploring the foraging behavior of bees and life histories of cacti. The goal is to gain insights that can inform effective conservation strategies to protect interdependent living things and environments.
Amarjit Mishra is a seasoned researcher who has devoted the majority of his life to study for the benefit of society. He had been employed as an assistant professor at Auburn University.
This document provides information about a symposium on diabetes organized by the SSR Medical College in Mauritius and the International Association of Medical and Biomedical Researchers (IAMBR). The symposium will take place on September 17-18, 2012 and will feature keynote speeches, poster presentations, and talks from international and national speakers on advances in managing diabetes. The document includes welcome messages, information about the organizing committees, the agenda, speaker biographies, and details about SSR Medical College.
Exposure assessment for occupational epidemiology part 1Retired
The aim of this lecture is to provide an introduction to occupational exposures and the strategies used in epidemiological studies to assess exposure of subjects.
15 Reasons Final Version v10 Web 8-25-09Lloyd Morgan
This document outlines 15 reasons for concern about potential risks of brain tumors from cellphone use, and provides background on the Interphone study. Some key points:
1) Independent studies have found a significant risk of brain tumors from cellphone use, while industry-funded studies have been less conclusive.
2) The Interphone study, a large industry-funded study of brain tumors, had design flaws that likely underestimated the risk, such as excluding young people and those too ill to participate.
3) Exposure limits for cellphones are based only on risks from heating effects, but thousands of studies show biological effects from non-thermal radiation levels as well.
4) The document urges applying the pre
The current pandemic shows us what happens if pathogens become easily transmissible from human to human, even if the mortality rate of a virus is relatively low. In view of this fact, it is almost unbelievable that since more than ten years, highly risky “gain-of-function” experiments are being conducted in various research labs where dangerous pathogens, such as avian influenza viruses and SARS-type viruses, are being adapted to human cells so that they ultimately become dangerous, i.e. potentially pandemic pathogens. Such experiments are ongoing – even with much more dangerous types of viruses – and, at least partially funded by taxpayers’ money. It is the responsibility of scientists worldwide to raise awareness about these huge risks among politicians and among the general public. A group of 50 scientists from different scientific disciplines and from various countries in Europa, America, Asia, Australia and New Zealand have drafted and signed the „Hamburg Declaration 2022“ with the goal of a worldwide ban of „gain-of-function” research with potentially pandemic pathogens as well as its supervision and continuous monitoring by an independent international regulatory agency. This Declaration follows the spirit of the “Göttinger Declaration of 1957” devoted to the threat by nuclear weapons
This document discusses ResearchGate, an online network for researchers. It describes how ResearchGate was founded, provides examples of research topics covered on the site, and shows graphs of how the "Find Researchers" function is used across disciplines. The document also shares stories from researchers who have used ResearchGate to find collaborators with similar interests and from the CEO of an organization that partners with ResearchGate to equip overseas labs. It concludes that ResearchGate aims to be a global network that is revolutionizing the scientific world through improved access to information and ability to connect with other researchers.
This document discusses ResearchGate, an online network for researchers. It describes how ResearchGate was founded, provides examples of research topics covered on the site, and shows graphs of how the "Find Researchers" function is used across disciplines. The document also shares stories from researchers who have used ResearchGate to find collaborators with similar interests and how the site helps connect scientists internationally to advance scientific efforts.
This document discusses ResearchGate, an online network for researchers. It describes how ResearchGate was founded, provides examples of research topics covered on the site, and shows graphs of how the "Find Researchers" function is used across disciplines. The document also shares stories from researchers who have used ResearchGate to find collaborators with similar interests and from the CEO of an organization that partners with ResearchGate to equip overseas labs. It concludes that ResearchGate aims to be a global network that is revolutionizing the scientific world through improved access to information and ability to connect with other researchers.
In Louis Pasteur's scientific career it is striking to note the exponential character
of the research he introduced in all the fields he opened up. He offered fabulous
opportunities to stereochemistry. He is acknowledged as one of the founders of
microbiology. He established the possibility of anaerobic life. He pointed the way
to epidemiology, public health, and the bacteriologic fight. He struggled against
the idea of spontaneous generation of life. He irrevocably substantiated the
microbial theory of infectious diseases. He demonstrated that bacterial virulence
could be attenuated, he evidenced immunity and generalised the vaccination
principle. He also was an incomparable experimenter.
The document summarizes research from the Institute for Genomic Biology (IGB) at the University of Illinois. It describes several projects that revealed new insights by reexamining familiar topics with improved tools and approaches. Princess Imoukhuede developed new techniques to identify cancer cell subpopulations to enable more personalized cancer treatments. A collaboration found that a small group of bees do most of the work in a hive, challenging assumptions about bee industriousness. James O'Dwyer improved an ecological model inspired by Lewis Carroll's Red Queen to better understand species evolution over long time periods. Hyunjoon Kong created a self-folding hydrogel that can slowly release drugs for tissue regeneration in a controlled manner, mimicking
Global Journal of Infectious Diseases and Clinical Research is an international peer-reviewed journal founded by a network of experts across the globe recognized as the International Infectiologists Network. The mission of GJIDCR is to promote and publish infectious diseases research in areas of basic sciences, clinical medicine and public health.
GJIDCR encourages research, education and dissemination of knowledge in the field of Infectious Diseases across the world thus promoting translational research by striking a synergy between basic science, clinical medicine and public health. The Journal intends to bring together scientists and academicians in Infectious Diseases to promote translational synergy between Laboratory Science, Clinical Medicine and Public Health. The Journal invites Original Articles, Clinical Investigations, Epidemiological Analysis, Data Protocols, Case Reports, Clinical Photographs, review articles and special commentaries. Students, Residents, Academicians, Public Health experts and scientists are all encouraged to be a part of this initiative by contributing, reviewing and promoting scientific works and science.
This document provides a summary of research being conducted at the University of Melbourne. It discusses:
1) A world-first breakthrough where researchers extracted genes from the extinct Tasmanian Tiger and observed their function in mice, showing DNA from extinct species can be studied.
2) An examination of art and mental illness led by Dr Anthony White, looking at how art by people experiencing mental illness is understood and exploring different interpretive frameworks.
3) Research led by Dr Caron Beaton-Wells on criminalising cartel misconduct, as Australia moves towards jail sentences for price fixing, which provides an opportunity for multi-disciplinary research contributing to policy in this area.
This document outlines 15 reasons for concern about potential links between cellphone use and brain tumors. It summarizes studies that have found such links, independent of industry funding. It also describes flaws in the industry-funded Interphone study that likely underestimate the risk of brain tumors from cellphone use. These flaws include selection bias, insufficient latency time, unrealistic definitions of "regular" use, and exclusion of certain groups. The document urges considering independent research and implementing precautionary measures to reduce exposure to cellphone radiation.
The summaries are:
1. The first global analysis of genome variation in honeybees has revealed a surprisingly high level of genetic diversity and indicates their origin is likely from Asia rather than Africa as previously thought. Honeybees are crucially important for pollinating one third of global food crops.
2. Researchers have found evidence that viruses infecting algae are driving the life and death cycles of algal blooms, which has implications for the climate as algae play a key role in absorbing carbon dioxide from the atmosphere.
3. Genetic research provides proof that the Philippine tarsier represents a new variety of primate found only in Southeast Asia, and it has become an iconic symbol for promoting
This article profiles Dr. Jason Hurlbert, an associate professor of chemistry at Winthrop University who does protein crystallography research. His goal is to determine the 3D structures of proteins, like sphingosine kinase which is overexpressed in some cancers, in order to help design inhibitors that could shut down cancer cells. He works with students in his lab, helping them gain hands-on research experience, which he sees as more important than his own research goals.
IDENTIFYING MOSQUITO LARVAE AND ITS DISTRIBUTION.pptxGraceArmenio
The document discusses a study conducted at Aurora National Science High School to identify mosquito larvae species and their distribution across the school's grounds. Field surveys were carried out using simple random sampling to collect mosquito larvae specimens, which were then identified morphologically based on traits of the head, thorax, and abdomen. The study aims to understand the local mosquito population and assist in targeted mosquito control strategies. However, limitations include challenges in accurate species identification and seasonal variations in larvae distribution.
For long time there is a human obsession to overcome death. In the past, man sought to overcome death through the religions. In the contemporary era, we started to believe that it would be possible to overcome death with the use of science and technology. The belief that, if it´s not possible to overcome death, but that it would be possible to extend the life is based on the fact that the life expectancy of men increased from 30 years in 1500, 37 years in 1800, 45 years in 1900, 46.5 years in 1950 and 80 years in 2012. The Superinteressante magazine (<http: />) published an article under the title Quem quer viver 1 000 anos? (Who wants to live 1000 years?), which states that the achievement of a longer existence in the 20th century resulted from the improvement of sanitary conditions in the cities and the creation of public health services. In addition, science discovered vaccines and antibiotics that made possible the disease prevention and control of epidemics. The increase in educational level and income also contributed to improving the quality of life and increase the longevity even more in the third or -. perhaps we can say - fourth age.
Biotherapy – the use of living organisms for the treatment of human and animal illness – is a practice known since antiquity. But it is not antiquated!
This document discusses New Approach Methodologies (NAM) for biomedical research as alternatives to traditional animal testing. It provides background on the 3Rs principle of replacing, reducing, and refining animal use. It then describes several NAMs including induced pluripotent stem cells, organ-on-chip models, disease-in-a-dish models using human tissues, increased use of biomarkers and 'omics technologies, and in silico methods like computational modeling. The document argues these methods can help map chemical toxicity more efficiently while also allowing studies of individual human variability, disease modeling, and multi-organ interactions in ways not possible with animal models. It concludes by providing additional resources for learning more about alternative methods.
This document discusses dual use research and some potential threats to humanity. It defines dual use research as biological research with a legitimate scientific purpose that could potentially be misused to threaten public health or national security. It examines several case studies where research had both benefits but also risks if misused, such as enhancing pathogens or understanding how to defeat immune systems. It discusses sequencing pathogens like anthrax and the risks if that information fell into the wrong hands. Overall, it recommends that researchers carefully weigh the risks and benefits of their work and consider potential dual use implications.
According to Amarjit Mishra, in some cases of severe asthma. There is chronic inflammation and repeated episodes of bronchoconstriction which leads to structural changes in the airway tissues
As per the doctors, during acute asthma attacks, quick-relief drugs like oral corticosteroids and short-acting beta-agonists (like albuterol) are frequently used to decrease inflammation and alleviate symptoms. However, biomedical researchers such as Amarjit Mishra, a great scientist,
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This document provides information about a symposium on diabetes organized by the SSR Medical College in Mauritius and the International Association of Medical and Biomedical Researchers (IAMBR). The symposium will take place on September 17-18, 2012 and will feature keynote speeches, poster presentations, and talks from international and national speakers on advances in managing diabetes. The document includes welcome messages, information about the organizing committees, the agenda, speaker biographies, and details about SSR Medical College.
Exposure assessment for occupational epidemiology part 1Retired
The aim of this lecture is to provide an introduction to occupational exposures and the strategies used in epidemiological studies to assess exposure of subjects.
15 Reasons Final Version v10 Web 8-25-09Lloyd Morgan
This document outlines 15 reasons for concern about potential risks of brain tumors from cellphone use, and provides background on the Interphone study. Some key points:
1) Independent studies have found a significant risk of brain tumors from cellphone use, while industry-funded studies have been less conclusive.
2) The Interphone study, a large industry-funded study of brain tumors, had design flaws that likely underestimated the risk, such as excluding young people and those too ill to participate.
3) Exposure limits for cellphones are based only on risks from heating effects, but thousands of studies show biological effects from non-thermal radiation levels as well.
4) The document urges applying the pre
The current pandemic shows us what happens if pathogens become easily transmissible from human to human, even if the mortality rate of a virus is relatively low. In view of this fact, it is almost unbelievable that since more than ten years, highly risky “gain-of-function” experiments are being conducted in various research labs where dangerous pathogens, such as avian influenza viruses and SARS-type viruses, are being adapted to human cells so that they ultimately become dangerous, i.e. potentially pandemic pathogens. Such experiments are ongoing – even with much more dangerous types of viruses – and, at least partially funded by taxpayers’ money. It is the responsibility of scientists worldwide to raise awareness about these huge risks among politicians and among the general public. A group of 50 scientists from different scientific disciplines and from various countries in Europa, America, Asia, Australia and New Zealand have drafted and signed the „Hamburg Declaration 2022“ with the goal of a worldwide ban of „gain-of-function” research with potentially pandemic pathogens as well as its supervision and continuous monitoring by an independent international regulatory agency. This Declaration follows the spirit of the “Göttinger Declaration of 1957” devoted to the threat by nuclear weapons
This document discusses ResearchGate, an online network for researchers. It describes how ResearchGate was founded, provides examples of research topics covered on the site, and shows graphs of how the "Find Researchers" function is used across disciplines. The document also shares stories from researchers who have used ResearchGate to find collaborators with similar interests and from the CEO of an organization that partners with ResearchGate to equip overseas labs. It concludes that ResearchGate aims to be a global network that is revolutionizing the scientific world through improved access to information and ability to connect with other researchers.
This document discusses ResearchGate, an online network for researchers. It describes how ResearchGate was founded, provides examples of research topics covered on the site, and shows graphs of how the "Find Researchers" function is used across disciplines. The document also shares stories from researchers who have used ResearchGate to find collaborators with similar interests and how the site helps connect scientists internationally to advance scientific efforts.
This document discusses ResearchGate, an online network for researchers. It describes how ResearchGate was founded, provides examples of research topics covered on the site, and shows graphs of how the "Find Researchers" function is used across disciplines. The document also shares stories from researchers who have used ResearchGate to find collaborators with similar interests and from the CEO of an organization that partners with ResearchGate to equip overseas labs. It concludes that ResearchGate aims to be a global network that is revolutionizing the scientific world through improved access to information and ability to connect with other researchers.
In Louis Pasteur's scientific career it is striking to note the exponential character
of the research he introduced in all the fields he opened up. He offered fabulous
opportunities to stereochemistry. He is acknowledged as one of the founders of
microbiology. He established the possibility of anaerobic life. He pointed the way
to epidemiology, public health, and the bacteriologic fight. He struggled against
the idea of spontaneous generation of life. He irrevocably substantiated the
microbial theory of infectious diseases. He demonstrated that bacterial virulence
could be attenuated, he evidenced immunity and generalised the vaccination
principle. He also was an incomparable experimenter.
The document summarizes research from the Institute for Genomic Biology (IGB) at the University of Illinois. It describes several projects that revealed new insights by reexamining familiar topics with improved tools and approaches. Princess Imoukhuede developed new techniques to identify cancer cell subpopulations to enable more personalized cancer treatments. A collaboration found that a small group of bees do most of the work in a hive, challenging assumptions about bee industriousness. James O'Dwyer improved an ecological model inspired by Lewis Carroll's Red Queen to better understand species evolution over long time periods. Hyunjoon Kong created a self-folding hydrogel that can slowly release drugs for tissue regeneration in a controlled manner, mimicking
Global Journal of Infectious Diseases and Clinical Research is an international peer-reviewed journal founded by a network of experts across the globe recognized as the International Infectiologists Network. The mission of GJIDCR is to promote and publish infectious diseases research in areas of basic sciences, clinical medicine and public health.
GJIDCR encourages research, education and dissemination of knowledge in the field of Infectious Diseases across the world thus promoting translational research by striking a synergy between basic science, clinical medicine and public health. The Journal intends to bring together scientists and academicians in Infectious Diseases to promote translational synergy between Laboratory Science, Clinical Medicine and Public Health. The Journal invites Original Articles, Clinical Investigations, Epidemiological Analysis, Data Protocols, Case Reports, Clinical Photographs, review articles and special commentaries. Students, Residents, Academicians, Public Health experts and scientists are all encouraged to be a part of this initiative by contributing, reviewing and promoting scientific works and science.
This document provides a summary of research being conducted at the University of Melbourne. It discusses:
1) A world-first breakthrough where researchers extracted genes from the extinct Tasmanian Tiger and observed their function in mice, showing DNA from extinct species can be studied.
2) An examination of art and mental illness led by Dr Anthony White, looking at how art by people experiencing mental illness is understood and exploring different interpretive frameworks.
3) Research led by Dr Caron Beaton-Wells on criminalising cartel misconduct, as Australia moves towards jail sentences for price fixing, which provides an opportunity for multi-disciplinary research contributing to policy in this area.
This document outlines 15 reasons for concern about potential links between cellphone use and brain tumors. It summarizes studies that have found such links, independent of industry funding. It also describes flaws in the industry-funded Interphone study that likely underestimate the risk of brain tumors from cellphone use. These flaws include selection bias, insufficient latency time, unrealistic definitions of "regular" use, and exclusion of certain groups. The document urges considering independent research and implementing precautionary measures to reduce exposure to cellphone radiation.
The summaries are:
1. The first global analysis of genome variation in honeybees has revealed a surprisingly high level of genetic diversity and indicates their origin is likely from Asia rather than Africa as previously thought. Honeybees are crucially important for pollinating one third of global food crops.
2. Researchers have found evidence that viruses infecting algae are driving the life and death cycles of algal blooms, which has implications for the climate as algae play a key role in absorbing carbon dioxide from the atmosphere.
3. Genetic research provides proof that the Philippine tarsier represents a new variety of primate found only in Southeast Asia, and it has become an iconic symbol for promoting
This article profiles Dr. Jason Hurlbert, an associate professor of chemistry at Winthrop University who does protein crystallography research. His goal is to determine the 3D structures of proteins, like sphingosine kinase which is overexpressed in some cancers, in order to help design inhibitors that could shut down cancer cells. He works with students in his lab, helping them gain hands-on research experience, which he sees as more important than his own research goals.
IDENTIFYING MOSQUITO LARVAE AND ITS DISTRIBUTION.pptxGraceArmenio
The document discusses a study conducted at Aurora National Science High School to identify mosquito larvae species and their distribution across the school's grounds. Field surveys were carried out using simple random sampling to collect mosquito larvae specimens, which were then identified morphologically based on traits of the head, thorax, and abdomen. The study aims to understand the local mosquito population and assist in targeted mosquito control strategies. However, limitations include challenges in accurate species identification and seasonal variations in larvae distribution.
For long time there is a human obsession to overcome death. In the past, man sought to overcome death through the religions. In the contemporary era, we started to believe that it would be possible to overcome death with the use of science and technology. The belief that, if it´s not possible to overcome death, but that it would be possible to extend the life is based on the fact that the life expectancy of men increased from 30 years in 1500, 37 years in 1800, 45 years in 1900, 46.5 years in 1950 and 80 years in 2012. The Superinteressante magazine (<http: />) published an article under the title Quem quer viver 1 000 anos? (Who wants to live 1000 years?), which states that the achievement of a longer existence in the 20th century resulted from the improvement of sanitary conditions in the cities and the creation of public health services. In addition, science discovered vaccines and antibiotics that made possible the disease prevention and control of epidemics. The increase in educational level and income also contributed to improving the quality of life and increase the longevity even more in the third or -. perhaps we can say - fourth age.
Biotherapy – the use of living organisms for the treatment of human and animal illness – is a practice known since antiquity. But it is not antiquated!
This document discusses New Approach Methodologies (NAM) for biomedical research as alternatives to traditional animal testing. It provides background on the 3Rs principle of replacing, reducing, and refining animal use. It then describes several NAMs including induced pluripotent stem cells, organ-on-chip models, disease-in-a-dish models using human tissues, increased use of biomarkers and 'omics technologies, and in silico methods like computational modeling. The document argues these methods can help map chemical toxicity more efficiently while also allowing studies of individual human variability, disease modeling, and multi-organ interactions in ways not possible with animal models. It concludes by providing additional resources for learning more about alternative methods.
This document discusses dual use research and some potential threats to humanity. It defines dual use research as biological research with a legitimate scientific purpose that could potentially be misused to threaten public health or national security. It examines several case studies where research had both benefits but also risks if misused, such as enhancing pathogens or understanding how to defeat immune systems. It discusses sequencing pathogens like anthrax and the risks if that information fell into the wrong hands. Overall, it recommends that researchers carefully weigh the risks and benefits of their work and consider potential dual use implications.
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According to Amarjit Mishra, in some cases of severe asthma. There is chronic inflammation and repeated episodes of bronchoconstriction which leads to structural changes in the airway tissues
As per the doctors, during acute asthma attacks, quick-relief drugs like oral corticosteroids and short-acting beta-agonists (like albuterol) are frequently used to decrease inflammation and alleviate symptoms. However, biomedical researchers such as Amarjit Mishra, a great scientist,
According to a new study carried out by Amarjit Mishra of Auburn University, air pollutants or allergens such as dust mites can produce oxidative stress in the airways, leading to increased inflammation and damage to airway cells.
Amarjit Mishra*
Assistant Professor (Former), Laboratory of Lung Inflammation, Department of Pathobiology, College of Veterinary Medicine, Auburn
University, Auburn, Alabama, United States
*Corresponding Author: Amarjit Mishra, Assistant Professor (Former), Laboratory of Lung Inflammation, Department of Pathobiology,
College of Veterinary Medicine, Auburn University, Auburn, Alabama, United States.
Dr. Amarjit Mishra has done many works, but his work on the significance of pharmacological targeting for the treatment of respiratory diseases based on the study of associated immunology is worth mentioning.
One of the most brilliant researchers of all time Dr. Amarjit Mishra, Ex-Assistant Professor of Auburn University has been working on identifying the various metabolic sensors that can be used for therapeutic purposes for asthma patients.
Amarjit Mishra was born in a small village in India, where he grew up in a low-income family with seven siblings. Despite their financial struggles, his parents instilled the importance of education in all of their children. Amarjit Mishra loved learning and was a dedicated student, but unfortunately, his family couldn’t afford to send him to school beyond the age of 10.
Dr.Amarjit Mishra has contributed to the review of the entire system of asthma pathogenesis by performing an extensive literature survey of the prior research as well as carrying out tests utilizing cutting-edge methods to further our understanding of the subject.
Amarjit Mishra also discusses the role of the mitochondrial Irg1/itaconate axis in controlling Th2 inflammation as a significant metabolic adaptation. Prior research has established a redox-dependent and related relationship between cross-presentation and allergen absorption by antigen-presenting dendritic cells.
Amarjit Mishra is a remarkable teaching professional who is heavily involved in research and teaching. He has been a member of the Auburn University team since many years, teaching a range of courses in the Department of Chemistry and Biochemistry.
One of the scientists who has done extensive research work in enhancing the understanding of this disease is the famous Veterinarian research scientist-turned-pulmonologist Amarjit Mishra.
Amarjit Mishra Assistant Professor at Auburn University, Yujie Guo, Li Zhang, Sunil More, Tingting Weng, and others, have recently conducted additional research on the function of neutrophils and their recruitment at a site.
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Strategies for Effective Upskilling is a presentation by Chinwendu Peace in a Your Skill Boost Masterclass organisation by the Excellence Foundation for South Sudan on 08th and 09th June 2024 from 1 PM to 3 PM on each day.
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
A workshop hosted by the South African Journal of Science aimed at postgraduate students and early career researchers with little or no experience in writing and publishing journal articles.
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Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
Chapter wise All Notes of First year Basic Civil Engineering.pptxDenish Jangid
Chapter wise All Notes of First year Basic Civil Engineering
Syllabus
Chapter-1
Introduction to objective, scope and outcome the subject
Chapter 2
Introduction: Scope and Specialization of Civil Engineering, Role of civil Engineer in Society, Impact of infrastructural development on economy of country.
Chapter 3
Surveying: Object Principles & Types of Surveying; Site Plans, Plans & Maps; Scales & Unit of different Measurements.
Linear Measurements: Instruments used. Linear Measurement by Tape, Ranging out Survey Lines and overcoming Obstructions; Measurements on sloping ground; Tape corrections, conventional symbols. Angular Measurements: Instruments used; Introduction to Compass Surveying, Bearings and Longitude & Latitude of a Line, Introduction to total station.
Levelling: Instrument used Object of levelling, Methods of levelling in brief, and Contour maps.
Chapter 4
Buildings: Selection of site for Buildings, Layout of Building Plan, Types of buildings, Plinth area, carpet area, floor space index, Introduction to building byelaws, concept of sun light & ventilation. Components of Buildings & their functions, Basic concept of R.C.C., Introduction to types of foundation
Chapter 5
Transportation: Introduction to Transportation Engineering; Traffic and Road Safety: Types and Characteristics of Various Modes of Transportation; Various Road Traffic Signs, Causes of Accidents and Road Safety Measures.
Chapter 6
Environmental Engineering: Environmental Pollution, Environmental Acts and Regulations, Functional Concepts of Ecology, Basics of Species, Biodiversity, Ecosystem, Hydrological Cycle; Chemical Cycles: Carbon, Nitrogen & Phosphorus; Energy Flow in Ecosystems.
Water Pollution: Water Quality standards, Introduction to Treatment & Disposal of Waste Water. Reuse and Saving of Water, Rain Water Harvesting. Solid Waste Management: Classification of Solid Waste, Collection, Transportation and Disposal of Solid. Recycling of Solid Waste: Energy Recovery, Sanitary Landfill, On-Site Sanitation. Air & Noise Pollution: Primary and Secondary air pollutants, Harmful effects of Air Pollution, Control of Air Pollution. . Noise Pollution Harmful Effects of noise pollution, control of noise pollution, Global warming & Climate Change, Ozone depletion, Greenhouse effect
Text Books:
1. Palancharmy, Basic Civil Engineering, McGraw Hill publishers.
2. Satheesh Gopi, Basic Civil Engineering, Pearson Publishers.
3. Ketki Rangwala Dalal, Essentials of Civil Engineering, Charotar Publishing House.
4. BCP, Surveying volume 1
How to Make a Field Mandatory in Odoo 17Celine George
In Odoo, making a field required can be done through both Python code and XML views. When you set the required attribute to True in Python code, it makes the field required across all views where it's used. Conversely, when you set the required attribute in XML views, it makes the field required only in the context of that particular view.
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
আমাদের সবার জন্য খুব খুব গুরুত্বপূর্ণ একটি বই ..বিসিএস, ব্যাংক, ইউনিভার্সিটি ভর্তি ও যে কোন প্রতিযোগিতা মূলক পরীক্ষার জন্য এর খুব ইম্পরট্যান্ট একটি বিষয় ...তাছাড়া বাংলাদেশের সাম্প্রতিক যে কোন ডাটা বা তথ্য এই বইতে পাবেন ...
তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
This document provides an overview of wound healing, its functions, stages, mechanisms, factors affecting it, and complications.
A wound is a break in the integrity of the skin or tissues, which may be associated with disruption of the structure and function.
Healing is the body’s response to injury in an attempt to restore normal structure and functions.
Healing can occur in two ways: Regeneration and Repair
There are 4 phases of wound healing: hemostasis, inflammation, proliferation, and remodeling. This document also describes the mechanism of wound healing. Factors that affect healing include infection, uncontrolled diabetes, poor nutrition, age, anemia, the presence of foreign bodies, etc.
Complications of wound healing like infection, hyperpigmentation of scar, contractures, and keloid formation.
How to Setup Warehouse & Location in Odoo 17 InventoryCeline George
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
How to Setup Warehouse & Location in Odoo 17 Inventory
Amarjit Mishra Excellence Establishes Himself as a Renowned Researcher
1. AMARJIT MISHRA EXCELLENCE ESTABLISHES
HIMSELF AS A RENOWNED RESEARCHER
The present picture of the world that we see
would not have transformed without the
contribution of these great personalities. Great
researchers, scientists and academicians that
exist in the present day, have shown inexplicable
abilities that help us define our existence and
human life. It is in the future that their names
will be engraved in the sands of time for their
work in the welfare of mankind owing to the
different inventions and discoveries that they are
making.
2. AMARJIT MISHRA ASSOCIATION WITH
AUBURN UNIVERSITY
Few of the areas in which he has conducted
his research has involved handling mice
models, besides handling a variety of cells
to study various immunological pathways.
His work also focuses on the immunological
aspect of respiratory diseases. As we know
that respiratory diseases are few of the
major causes of illness and death in
contemporary times, the work by Amarjit
Mishra Auburn University
3. Amarjit Mishra has been able to show
direction to many budding researchers.
Amarjit Mishra also has a prominent name for
involving young researchers through
activities such as conferences and discussions
on various forums. He is also known amongst
his fellow mates for fairly recognising the
efforts put forth by them, showing the
presence of professional integrity.
DIRECTION GIVEN BY AMARJIT MISHRA
AUBURN UNIVERSITY PROFESSOR
4. Amarjit Mishra is an inspiring figure for the
researchers in the field of biology. He has
done many works, but his work on the
significance of pharmacological targeting for
the treatment of respiratory diseases based
on the study of associated immunology is
worth mentioning.
5. Amarjit Mishra is a highly dextrous research
fellow and academician who is amongst the
leading scientists of the contemporary times.
His contributions in the field of immunology,
cell biology, genetics and genomics in both
animals and humans have transformed the
field of scientific research.
Source:- https://examinnews.com/amarjit-mishra-excellence-establishes-himself-as-a-renowned-researcher/