This document discusses building a Child Data Centre of Alberta to analyze linked population data and inform social and health policy. It would utilize secondary data, including administrative, service delivery, and research data. The Child Data Centre would include a Child Population Data Repository, Child Research Data Repository, and Community Service Agency Data Repository. It would generate new knowledge through secondary analysis of longitudinal linked data from multiple ministries to study outcomes over time and evaluate policies. Challenges include ensuring privacy, security, and ethical use of data from various sources. The goal is to improve outcomes for children and families through timely evidence-informed policy.
Agencies such as the NSF and NIH require data management plans as part of research proposals and the Office of Science and Technology Policy (OSTP) is requiring federal agencies to develop plans to increase public access to results of federally funded scientific research. These slides explore sustainable data sharing models, including models for sharing restricted-use data. Demos of these models and tips for accessing public data access services are provided as well as resources for creating data management plans for grant applications.
Understanding ICPSR - An Orientation and Tours of ICPSR Data Services and Edu...ICPSR
This is ICPSR's core workshop deck designed to introduce, remind, and refresh your knowledge of ICPSR. It contains four "tours" or sub-presentations describing ICPSR's general reason for being, it's social and behavioral research data complete with search strategies, its training, educational, and instructional resources, and its data management and curation services, data repository options, and support resources (content and budget estimates) for those writing grant proposals.
Instructional Data Sets from Q-step Launch Event (Univ of Exeter) 3-20-2014ICPSR
Presentation about using social science data in the classroom and creating (and finding) resources with which to do it. Addresses both substantive courses and research methods/statistics courses.
Agencies such as the NSF and NIH require data management plans as part of research proposals and the Office of Science and Technology Policy (OSTP) is requiring federal agencies to develop plans to increase public access to results of federally funded scientific research. These slides explore sustainable data sharing models, including models for sharing restricted-use data. Demos of these models and tips for accessing public data access services are provided as well as resources for creating data management plans for grant applications.
Understanding ICPSR - An Orientation and Tours of ICPSR Data Services and Edu...ICPSR
This is ICPSR's core workshop deck designed to introduce, remind, and refresh your knowledge of ICPSR. It contains four "tours" or sub-presentations describing ICPSR's general reason for being, it's social and behavioral research data complete with search strategies, its training, educational, and instructional resources, and its data management and curation services, data repository options, and support resources (content and budget estimates) for those writing grant proposals.
Instructional Data Sets from Q-step Launch Event (Univ of Exeter) 3-20-2014ICPSR
Presentation about using social science data in the classroom and creating (and finding) resources with which to do it. Addresses both substantive courses and research methods/statistics courses.
Research Data Management in Academic Libraries: Meeting the ChallengeSpencer Keralis
TLA Program Committee sponsored Preconference talk from Texas Library Association Conference 2013.
CPE#388: SBEC 1.0; TSLAC 1.0
April 24, 2013; 4:00 -4:50 pm
Managing research data is a hot topic in academic libraries. With increased government oversight of publicly-funded research projects, librarians must strive to meet the demand for innovative solutions for managing research information and training the new eneration of librarians to address this issue.
Meeting Federal Research Requirements for Data Management Plans, Public Acces...ICPSR
These slides cover evolving federal research requirements for sharing scientific data. Provided are updates on federal agency responses to the 2013 OSTP memo, guidance on data management plans, resources for data management and curation training for staff/researchers, and tips for evaluating public data-sharing services. ICPSR's public data-sharing service, openICPSR, is also presented. Recording of this presentation is here: https://www.youtube.com/watch?v=2_erMkASSv4&feature=youtu.be
This presentation was provided by Holly Falk-Krzesinski of Elsevier during the NISO event, "Is This Still Working? Incentives to Publish, Metrics, and New Reward Systems," held on February 20, 2019.
This slide deck provides an overview and resources to respond to the OSTP memo with the subject: Increasing Access to the Results of Federally Funded Scientific Research issued by John P. Holdren in February 2013. It provides resources and information agencies, foundations, and research projects can use to assemble achieve public access to scientific data in digital formats.
RDAP 16: Sustainability of data infrastructure: The history of science scienc...ASIS&T
Research Data Access and Preservation Summit, 2016
Atlanta, GA
May 4-7, 2016
Part of Panel 2, Sustainability
Presenter:
Kristin Eschenfelder, University of Wisconsin-Madison
Panel Leads:
Kristin Briney, University of Wisconsin-Milwaukee & Erica Johns, Cornell University
Use of monitoring data for evidence-based decision making: A factor analysisIRC
Presentation given by Marieke Adank during the IRC Symposium All Systems Go! on 14 March 2019. This session was organised by Heather Skilling (DAI), in collaboration with Brain Banks (GETF), Nick Dickinson (WAHSNote) and Marieke Adank (IRC).
Digital transformation to enable a FAIR approach for health data scienceVarsha Khodiyar
Invited talk for ConTech Pharma on 1st March 2022
Abstract
Health Data Research UK is the UK’s national institute for health data science, with a mission to unite the UK’s health data to enable discoveries that improve people’s lives. In this talk, Dr Varsha Khodiyar will outline how HDR UK is bringing together disparate health data from all four countries of the United Kingdom, creating the infrastructure to enable discovery of and access to health data, and the convening standards making bodies to improve data linkage and data reuse. Varsha will also discuss how HDR UK is moving beyond the traditional confines of FAIR data to also ensure that data sharing and data use is transparent and ‘fair’ for the patients and lay public who are the subjects of these datasets.
RDAP13 Mark Parsons: The Research Data Alliance: Making Data WorkASIS&T
Mark Parsons, Rensselaer Polytechnic Institute
Mark A. Parsons and Francine Berman: "The Research Data Alliance: Making Data Work"
Panel: Global scientific data infrastructure
Research Data Access & Preservation Summit 2013
Baltimore, MD April 4, 2013 #rdap13
Research Data Management in Academic Libraries: Meeting the ChallengeSpencer Keralis
TLA Program Committee sponsored Preconference talk from Texas Library Association Conference 2013.
CPE#388: SBEC 1.0; TSLAC 1.0
April 24, 2013; 4:00 -4:50 pm
Managing research data is a hot topic in academic libraries. With increased government oversight of publicly-funded research projects, librarians must strive to meet the demand for innovative solutions for managing research information and training the new eneration of librarians to address this issue.
Meeting Federal Research Requirements for Data Management Plans, Public Acces...ICPSR
These slides cover evolving federal research requirements for sharing scientific data. Provided are updates on federal agency responses to the 2013 OSTP memo, guidance on data management plans, resources for data management and curation training for staff/researchers, and tips for evaluating public data-sharing services. ICPSR's public data-sharing service, openICPSR, is also presented. Recording of this presentation is here: https://www.youtube.com/watch?v=2_erMkASSv4&feature=youtu.be
This presentation was provided by Holly Falk-Krzesinski of Elsevier during the NISO event, "Is This Still Working? Incentives to Publish, Metrics, and New Reward Systems," held on February 20, 2019.
This slide deck provides an overview and resources to respond to the OSTP memo with the subject: Increasing Access to the Results of Federally Funded Scientific Research issued by John P. Holdren in February 2013. It provides resources and information agencies, foundations, and research projects can use to assemble achieve public access to scientific data in digital formats.
RDAP 16: Sustainability of data infrastructure: The history of science scienc...ASIS&T
Research Data Access and Preservation Summit, 2016
Atlanta, GA
May 4-7, 2016
Part of Panel 2, Sustainability
Presenter:
Kristin Eschenfelder, University of Wisconsin-Madison
Panel Leads:
Kristin Briney, University of Wisconsin-Milwaukee & Erica Johns, Cornell University
Use of monitoring data for evidence-based decision making: A factor analysisIRC
Presentation given by Marieke Adank during the IRC Symposium All Systems Go! on 14 March 2019. This session was organised by Heather Skilling (DAI), in collaboration with Brain Banks (GETF), Nick Dickinson (WAHSNote) and Marieke Adank (IRC).
Digital transformation to enable a FAIR approach for health data scienceVarsha Khodiyar
Invited talk for ConTech Pharma on 1st March 2022
Abstract
Health Data Research UK is the UK’s national institute for health data science, with a mission to unite the UK’s health data to enable discoveries that improve people’s lives. In this talk, Dr Varsha Khodiyar will outline how HDR UK is bringing together disparate health data from all four countries of the United Kingdom, creating the infrastructure to enable discovery of and access to health data, and the convening standards making bodies to improve data linkage and data reuse. Varsha will also discuss how HDR UK is moving beyond the traditional confines of FAIR data to also ensure that data sharing and data use is transparent and ‘fair’ for the patients and lay public who are the subjects of these datasets.
RDAP13 Mark Parsons: The Research Data Alliance: Making Data WorkASIS&T
Mark Parsons, Rensselaer Polytechnic Institute
Mark A. Parsons and Francine Berman: "The Research Data Alliance: Making Data Work"
Panel: Global scientific data infrastructure
Research Data Access & Preservation Summit 2013
Baltimore, MD April 4, 2013 #rdap13
Over the past 10 years, research systems have evolved from systems that focused on how to structure and record information on research, to systems capable of allowing significant insights to be derived based upon years of high quality information. In 2015, the maturity of the information now collected within many Current Research Information Systems, and the insights that this can provide is of equal or greater value than the insights that could be gleaned from established externally provided research metrics platforms alone. The ability to intersect these external and internal worlds provides new levels of strategic insight not previously available. With the addition of platforms that track altmetrics, and their ability to connect university publications data with a constant flow of real time attention level metrics, an image of a dynamic network of systems emerges, connected together by ever turning ‘cogs’ pushing and translating information. Add to this, the success of ORCID as pervasive researcher identifier infrastructure, and CASRAI as the emerging social contract for information exchange, and it becomes possible to extend this network back from the systems that track and record research information, through to the platforms through which research knowledge is created. The ‘Mechanics’ of this network of systems is more than just getting the ‘plumbing’ right. As research information moves through the network, its audience and purpose changes, the requirements for contextual metadata can also change. This presentation will explore the lived experience of Research Data Mechanics at Digital Science though illustrating how connections between Figshare, Altmetric, Symplectic Elements, and Dimensions can both enhance research system capability and reduce the burden on researchers, and research administration.
Ethical Priniciples for the All Data RevolutionMelissa Moody
A presentation by Stephanie Shipp, from the Research Highlights session at the 2019 Women in Data Science Charlottesville Conference. Hosted by the UVA Data Science Institute.
A call to librarians to use their library powers in the community beyond the walls of their institutions as the open data folks need their knowledge!
Title:
Open Sesame: Open Data, Data Liberation and New Opportunities for Libraries
Abstract:
Cities and data producers are quickly embracing Open Data, albeit unevenly. The Data Liberation Initiative (DLI) has been a pioneer in broadening access to data for nearly two decades. This session will examine the relevance of Data Liberation in terms of Open Data and explore how librarians can step up to the plate to make Open Data/Open Government as successful as DLI.
Speakers:
- Wendy Watkins, Data Librarian, Carleton University
- Ernie Boyko, Adjunct Data Librarian, Carleton University
- Tracey P. Lauriault, Post Doctoral Fellow, Carleton University (tlauriau@gmail.com)
- Margaret Haines, University Librarian, Carleton University
Stuart Macdonald steps through the process of creating a robust data management plan for researchers. Presented at the European Association for Health Information and Libraries (EAHIL) 2015 workshop, Edinburgh, 11 June 2015.
Dr. Charles Macias (Texas Children's Hospital) talks about the inception, challenges, and logistics of a large Research Network, the PEMCRC (Pediatric Emergency Medicine Collaborative Research Committee).
Sourcing health data for open-access collectionGreg D'Arcy
La Trobe University Library partnered with our Health Sciences academics to procure datasets from two Victorian regional health service providers in 2014/15 and from these created a publically available, healthy communities data collection for research purposes
Sdal air education workforce analytics workshop jan. 7 , 2014.pptxkimlyman
The American Institutes for Research (AIR) and Virginia Tech are collaborating to explore and develop new approaches to combining, manipulating and understanding big data. The two are also looking at how big data analytics can help answer questions critical to solving issues in education, workforce, health, and human and social development. They held two workshops on January 7 and 27, 2014- the first on Education and Workforce Analytics and the second on Health and Social Development Analytics.
Optimising benefits from Canadian Research - Jim WoodgettCASRAI
Janet Halliwell, Chair CASRAI; Co-Chair Admin Burden Canada collective; Chair CSPC
Dominique Bérubé, Vice-President Research Programs, SSHRC
Jim Woodgett, Director of Research, Lunenfeld-Tanenbaum Research Institute
Optimising benefits from Canadian Research - Janet HalliwellCASRAI
Janet Halliwell, Chair CASRAI; Co-Chair Admin Burden Canada collective; Chair CSPC
Dominique Bérubé, Vice-President Research Programs, SSHRC
Jim Woodgett, Director of Research, Lunenfeld-Tanenbaum Research Institute
Admin Burden in Canada (ABC) Introductory Panel Discussion (CA, UK and US ove...CASRAI
Admin Burden in Canada (ABC) Introductory Panel Discussion (CA, UK and US overview)
David Robinson
Executive Vice Provost & Professor
Oregon Health & Science University (US)
ABC Project 1 - Piloting Auto-upload of Standardized Funding Award Results - ...CASRAI
ABC Project 1 - Piloting Auto-upload of Standardized Funding Award Results
Judith L. Chadwick
Assistant Vice-President, Research Services
University of Toronto
Bob Dirstein
Dirstein Consulting Inc.
w/University of Toronto
ABC Project 2 - Launching an ORCID Consortia in Canada - Clare Appavoo & Geof...CASRAI
Launching an ORCID Consortia in Canada
Clare Appavoo
Executive Director
Canadian Research Knowledge Network (CRKN)
Geoffrey Harder
Associate University Librarian
University of Alberta
Mark Leggott
Executive Director
Research Data Canada (RDC)
Introduction to the Federal Demonstration Partnership (FDP) of the US - David...CASRAI
Introduction to the Federal Demonstration Partnership (FDP) of the US
David Robinson
Executive Vice Provost & Professor
Oregon Health & Science University (US)
Tutorial: the new Portage Research Data Management Planning Tool - Chuck Hump...CASRAI
Tutorial: the new Portage Research Data Management Planning Tool
Chuck Humphrey
Director, Portage Network
University of Alberta
Dylanne Dearborn
Physics Library
University of Toronto Libraries
How Do I Know Thee? Let Me Count the Ways: Panel 2: Jeffrey Alexander & Patri...CASRAI
All R&D organizations classify their research activities, either implicitly (e.g., by laboratory or department) or explicitly (e.g., by creating taxonomies to define and map research disciplines and domains). However the lack of clear standards for doing so impedes the sharing and aggregation of data on R&D activities. In this panel the speakers will provide an overview of the organizational needs driving the development of a classification of R&D activities, use cases for such a classification, and the potential advantages of international coordination across such classifications.
Classifying R&D: Why and How Organizations Develop Taxonomies for Research Fi...CASRAI
All R&D organizations classify their research activities, either implicitly (e.g., by laboratory or department) or explicitly (e.g., by creating taxonomies to define and map research disciplines and domains). However the lack of clear standards for doing so impedes the sharing and aggregation of data on R&D activities. In this workshop, Jeff Alexander and Patrick Lambe will provide an overview of the organizational needs driving the development of a classification of R&D activities, use cases for such a classification, and the potential advantages of international coordination across such classifications. The workshop, based heavily on a study they conducted for the National Center for Science & Engineering Statistics at the U.S. National Science Foundation, will review alternate approaches to both developing R&D classifications, and streamlining the process of classifying research programs and projects. Topics to be covered include examples of international R&D classifications and their development (such as the Australia-New Zealand Standard Research Classification), design principles for R&D classifications, and new automated and semi-automated classification techniques using semantic analysis and machine learning.
How Do I Know Thee? Let Me Count the Ways: Sarah Moreault, Monica Valsangkar-...CASRAI
Classification of research plays an integral role in the functioning of research funding organizations. As such it is important to have a classification system for efficient research data collection, use, analysis and reporting. Hear about lessons learned as well as key limitations and challenges for the implementation of a standard approach to classification through the analyses of different international standards currently in use with respect to their governance, development, implementation and maintenance
Provincial Perspectives on Research Impacts: Eddy Nason, Renata Osika, Krista...CASRAI
When we say “Research Impact” many things come to mind and the reasons for why we are concerned with it vary. The underlying concepts are complex and often require expert knowledge, and there is also no one single interpretation or answer. Stakeholders are diverse and so are the means of communication. Therefore across Canada, we continue to seek more consistent and harmonized ways of telling the “Impact Story.” The panel will reflect on harmonization efforts across provinces.
Lightning Reports on 2015 CASRAI Standards Work: Data Management PlanCASRAI
Get an overview of all CASRAI standards projects from the past year delivered by the project leads. Includes Project CRediT, Peer Review Citations, Snowball Metrics, Data Management Plans, Open Access Reporting and Organizational ID standards.
Closing the Loop - Technology ImplementationsCASRAI
Thorsten Hoellrigl, Thomas Vestam. Targeted at representatives of IT departments and software suppliers. Hearing from early technology adopters of CASRAI standards on progress and lessons learned.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
1. Xinjie Cui BMed PhD MBA
Chief Analytics Officer
Building a Child Data Center
with Linked Population Data
to Inform Policy
2. CYDL Link Analyze Inform 2
The Need and The Opportunity
Complex social, health, and education policies REQURE
• More
• Relevant
• Timely
Evidence for decision
Advancement of information technology ENABLES
• More and better data collection and store (digital storage)
• More, better, new methodologies for data discovery
3. CYDL Link Analyze Inform 3
Secondary Data and Secondary Analysis
Secondary analysis – utilization of existing data
Secondary data
• Administrative data – collected to conduct business
• Service delivery data – collected to provide services
• Research data – collected to answer research questions
Benefits
• Potentially faster
• Relatively low cost
4. CYDL Link Analyze Inform 4
Usefulness of Secondary Data
• Monitor/track health and wellbeing of the
population (identify trends and issues)
• Discover patterns and relationships of
risk/resilient factors and outcomes
• Support development of strategies and policies
• Evaluate effectiveness of policies, programs,
and services
• Inform performance measurement and result
based budgeting
5. CYDL Link Analyze Inform 5
Child Data Centre of Alberta
A data and research facility
–Wide variety of data holdings with
potential for linkage
–Value added services
–Broad access by qualified policy
analysts and researchers
6. CYDL Link Analyze Inform 6
Vision
Improved outcomes for children and
family by informing social and health
policy, practice, and service planning
Through
New knowledge generation
Timely and relevant evidence for policy and practice
Capacity building
7. CYDL Link Analyze Inform 7
ACCFCR Board
ACCFCR
Child
Population
Data
Repository
Child
Research Data
Repository
Child Data Centre of Alberta
Community
Service
Agency Data
Repository
Children First Act
8. CYDL Link Analyze Inform 8
Government Administrative Data
Pros:
• Populations based (all Albertans)
• Longitudinal
• Linked data may address system-wide and policy relevant
questions well and provides opportunity to study broad
determinants of health
Cons:
• Lack details on some measures such as behavioral risk
factors, physical measurements etc.
• Inconsistent measures; recording and coding errors
• Subject to misinterpretation if not familiar with data
collection and manipulation process
9. CYDL Link Analyze Inform 9
Service Delivery Data
From community agencies and service organizations
Pros
• Detailed in depth data
• Intervention and services focused
• May contain risk factors and qualitative measures
Cons
• Inconsistency across agencies/clinics
– standards, capacity, systems, services…
• Large number of organization of different kinds
10. CYDL Link Analyze Inform 10
Research Data
• Public funded research data exist in isolation
• Often times, when research project is done,
data gets destroyed or shelved – seldom gets
reused or further analyzed
Modern Research
• Collaborative, multi-disciplinary, and answer
complex questions
• Data are large in volume and digitized
• Great value for repurpose and reuse
11. CYDL Link Analyze Inform 11
Research Data Sharing
• Trend around the world:
– Funding Agencies: NIH USA, MRC UK,
Tri-council Canada
– Open access content: PLOS
• Lack of centralized place for storage,
management and further utilization
• Especially lack of support around
secondary use
12. CYDL Link Analyze Inform 12
Child Data Centre of Alberta
• Securely stored, cleaned, catalogued,
enhanced, managed, and potentially
linkable. (where and when it is possible and
appropriate).
• Access and use of data facilitated, managed
and supported – value add
• Information privacy protected
13. CYDL Link Analyze Inform 13
ACCFCR Board
ACCFCR
Child
Population
Data
Repository
Child
Research Data
Repository
Child Data Centre of Alberta
Community
Service
Agency Data
Repository
Children First Act
14. CYDL Link Analyze Inform 14
Child and Youth Data Lab
As the Administrative Data component of CDCA
• Links and analyzes government
administrative data – cross-sector
• For policy relevant research
• With a focus on children, youth and families
in Alberta
15. CYDL Link Analyze Inform 15
Partnering Ministries
• Human Services (Lead ministry)
• Health (HUB for data matching)
• Education
• Innovation and Advanced Education
• Justice and Solicitor General
• Aboriginal Relations
16. CYDL Link Analyze Inform 16
CYDL Research Process
• Partnership – working closely together
• Process
– Identification of research priorities
– Project development/Study design
– Identification of data elements
– Feasibility assessment (data and privacy)
– Research Ethics approval
– Data sharing agreements and Privacy Impact Assessment
– Data linkage and transfer
– Data validation, analysis, and interpretation
– Report generation and dissemination/knowledge mobilization
• Involvement of ministries throughout the
process
17. CYDL Link Analyze Inform 17
Characteristics of CYDL
• Authentic Partnership
– Ministries involvement throughout the full
research cycle
• Anonymous Linkage
– Data hashed at source
• Policy Relevant
– Research questions are policy driven
• Project Based Model
– No population repository yet
18. CYDL Link Analyze Inform 18
Experience of Albertan Youth over Time
• Longitudinal design
• Six years of data 2005/06 to 2010/11
• Broad scope:
• 5 ministries
• 25 databases covering more program and service
areas
• Over 250 variables
• Key indicators:
• Demographic
• Socio-economic status
• Mental health status
• Educational achievement
• Health service use
19. CYDL Link Analyze Inform 19
0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30
All programs
Health
Child intervention
Child support services
FSCD
Child health benefits
Child care subsidy
Education
Corrections
Offence charges
Advanced Education
Income support learners
Income support
AISH
Adult health benefits
PDD
Advancing Futures bursary
Age (years)
CYDL Longitudinal Project Sample Indicators
Young adulthood
Childhood
Youth
Early childhood
Court outcomes
Type of charge, charge history
Program and institution details
Household type, enrollment details
Client type, household type
Disability type, household indicators
Type of benefits
Type and amount of support
Enrollment and support details
Perinatal indicators, diagnoses, mental health status
Type of abuse/neglect, type of services provided, history
Type of order, reason for file closure
Type of disability, duration of services, reason for file closure
Type of benefit received, age at first use
Type of program, reason for care, duration
Achievement, school indicators, special programs, high school completion
Gender, age, socio-economic status, region of residence/service, Aboriginal status (if available)
20. CYDL Link Analyze Inform 20
Types of Analysis
Time trends
Policy impact over time
Service use patter over time
Specific topics such as
• Youth transition
• Resiliency
• Early childhood
development
• Poverty
• Persistent offenders
• FASD
• Aboriginal youth
• Special education
• Self-harm
21. CYDL Link Analyze Inform 21
Research Data Repository
• Stakeholders consultation
• Best practice - technical, management,
ethical, metadata, and data governance
• Principal Investigators of two cohort studies
on board and other datasets
• Design of processes and structure
22. CYDL Link Analyze Inform 22
Research Data Repository
• Set up governance structure
• Build technical infrastructure – enclave
• Transfer initial datasets
• Develop metadata
• Pilot early adopter projects
• Support access and use
23. CYDL Link Analyze Inform 23
Research Data Repository
• Develop communication/marketing plan to
promote CDCA
• Identify potential research datasets for
repository
• Provide training opportunities for students
and trainees
• Identify opportunities to develop Service
Delivery Data component
• Explore feasibility of integration with CYDL
component
24. CYDL Link Analyze Inform 24
Issues for Consideration
Research Ethics
• Consent, Re-consent, Agreements
Information Privacy and Confidentiality
• Right to privacy and confidentiality as public good
Data Security
• Technology (increased risk but also new tools to
protect)
• Data linkage (increased risk for re-identifiability)
Original Researchers’ Involvement
• Researchers’ input, flexibility
25. CYDL Link Analyze Inform 25
Success Factors
• Independent
• Outside of government
• Outside of universities
• Authentic Partnership
• Engagement of research community
• Political and Executive support
• Enabling data sharing legislation
• Sponsors and Champions at multiple levels
• Strong Governance and Accountability structure
and process
• Sustainable funding and Designated resources
• Strong project management and coordination
• Dedicated staff and technical/research expertise
• Persistence and patience