Rbc vs wbc, basic difference between RBCs & WBCs, blood cells, blood

2. 1. Alternative Name
 RBCs:- Erythrocytes
 WBCs:- Leucocytes
2. Origin
 RBCs:- In the embryonic phase, they are formed in the liver and
spleen. However, after birth, they are formed in the red bone
marrow.
 WBCs:- They are formed in red bone marrow, lymph nodes,
spleen etc.
3. Process of formation
 RBCs:- Formation of RBCs is called Erythropoiesis.
 WBCs:- Formation of WBCs is called Leucopoiesis.

3. 4. Abundance
 RBCs:- More abundant (4-5 million/mm3) They are most abundant
cell in the blood, accounting for about 40-45% of its volume.
 WBCs:- They are much fewer in number than RBCs, accounting for
about 1% of blood (8000/ mm3).
5. Size
 RBCs:- Smaller than WBCs (0.008 mm diameter)
 WBCs:- Larger than RBCs (0.02mm)
6. Shape
 RBCs:- Biconcave disc-shaped.
 WBCs:- Irregular or round in shape.

4. 7. Colour
 RBCs:- Red cells are pinkish‐brown in color.
 WBCs:- White cells are colorless.
8. Hemoglobin
 RBCs:- The complex protein, hemoglobin, is the major constituent
of RBCs.
 WBCs:- Hemoglobin is absent in WBCs.
9. Nucleus
 RBCs:- The nucleus is absent (anucleate).
 WBCs:- Present and may be bilobed, irregular or round.
10. Circulatory system
 RBCs:- Belong to the cardiovascular system.
 WBCs:- Belong to the lymphatic system.

5. 11. Types
 RBCs:- Single type.
 WBCs:- In healthy people, there are at least five types of white
cells in the circulating blood. White cells are divided into
granulocytes, monocytes, and lymphocytes.
12. Number Increment
 RBCs:- Number increases during exercise or when at high
altitudes.
 WBCs:- The infection leads to an increase in the number of
WBCs.
13. Life span
 RBCs:- The average life span of 120 days.
 WBCs:- Life span ranges from 5-21 days.

6. 14. Motility
 RBCs:- Non-motile but can move through circulation and have the
ability to squeeze through small capillaries.
 WBCs:- Generally motile.
15. Movement
 RBCs:- Movement is Primarily between the cardiovascular
system.
 WBCs:- Between the cardiovascular and lymphatic systems.
16. Movement type
 RBCs:- Do not leave the blood vessel.
 WBCs:- They can leave blood from capillaries and land in tissues.

7. 17. Rouleaux formation
 RBCs:- Forms stacks or aggregation called Rouleaux.
 WBCs:- Do not form Rouleaux.
18. Related disorders
 RBCs:- Disorders result in anemia, thalassemia, polycythemia
Vera, etc.
 WBCs:- Lymphoma, Leukemia, Myelodysplastic syndrome (MDS).
19. Function
 RBCs:- Carry respiratory gases- oxygen and carbon dioxide. Also,
it contributes to blood viscosity.
 WBCs:- Phagocytosis and defensive role including antibody
production.