This document provides guidance on developing a high-quality research question. It instructs the user to brainstorm what they know and want to know about their topic without judgment. The user then selects the 10 best statements or questions and converts any statements into questions. Any closed questions should be highlighted. The document explains that open questions are better for research as they cannot be answered simply and require analysis. An example is provided to illustrate the difference between a closed and open question. The user is prompted to change any closed questions into open questions. Question stems are then provided to help improve the questions. Finally, the document instructs the user to evaluate their final research question.