The Pythagorean theorem is a fundamental mathematical concept used to relate the sides of a right-angled triangle, stating that the square of the hypotenuse is equal to the sum of the squares of the other two sides. This theorem allows for the calculation of unknown side lengths and has applications such as determining if a triangle is right-angled and finding the diagonal of a square. The document also includes a proof of the theorem and guidance on its application in problem-solving.