Pharmacovigilance AND ADVERSE DRUG REACTIONS.
MONITORING REPORTING ROLE OF PHARMACIST.
CLASSIFICATION OF ADR. MECHANISM OF ADR
ROLE OF PHARMACIST IN MANAGING ADR. AUGMENTED, BIZZARE, CONTINOUS, DELAYED, END OF TREATMENT, ABCD, ABCDE.
detection methods of Adverse drug reactions, postal survey method, Reporting of Adverse drug reactions, Preventability assessment, predictability assessments
SEVERITY AND SERIOUSNESS ASSESSMENT OF ADR’S
Definitions, Severity assessment, Seriousness assessment
Naranjo algorithm, Preventability assessment
By
Ms. B. Mary Vishali
Department of Pharmacology
Pharmacovigilance AND ADVERSE DRUG REACTIONS.
MONITORING REPORTING ROLE OF PHARMACIST.
CLASSIFICATION OF ADR. MECHANISM OF ADR
ROLE OF PHARMACIST IN MANAGING ADR. AUGMENTED, BIZZARE, CONTINOUS, DELAYED, END OF TREATMENT, ABCD, ABCDE.
detection methods of Adverse drug reactions, postal survey method, Reporting of Adverse drug reactions, Preventability assessment, predictability assessments
SEVERITY AND SERIOUSNESS ASSESSMENT OF ADR’S
Definitions, Severity assessment, Seriousness assessment
Naranjo algorithm, Preventability assessment
By
Ms. B. Mary Vishali
Department of Pharmacology
REVIEWING THE CLINICIANS PRESCRIPTION AND TREATMENT PROGRESSION IS THE FUNDAMENTAL RESPONSIBILITY OF PHARMACIST. THIS PRESENTATION WILL DEAL WITH VARIOUS ASPECTS OF REVIEWING PATIENT DRUGTHERAPY PLAN
History and Progress of Pharmacovigilance, Significance of Safety Monitoring, Pharmacovigilance in India And International Aspects, WHO International Drug Monitoring Programme, WHO and Regulatory Terminologies of ADR, Evaluation of Medication Safety, Establishing Pharmacovigilance Centres in Hospitals, Industry and National Programmes Related to Pharmacovigilance, Roles and Responsibilities in Pharmacovigilance, International Non-Proprietary Names for Drugs, International Classification of Diseases, Passive and Active Surveillance, Comparative Observational Studies, Targeted Clinical Investigations and Vaccine Safety Surveillance, Aris G Pharmacovigilance, VigiFlow, Statistical Methods for Evaluating Medication Safety Data
Defined daily dose-DDD
B Pharm, Pharm D and medicine syllabus
Useful for examination and regulatory function information
Useful for Pharmacovigilance interview and medical coding also.
Good Luck and all the best!!!
REVIEWING THE CLINICIANS PRESCRIPTION AND TREATMENT PROGRESSION IS THE FUNDAMENTAL RESPONSIBILITY OF PHARMACIST. THIS PRESENTATION WILL DEAL WITH VARIOUS ASPECTS OF REVIEWING PATIENT DRUGTHERAPY PLAN
History and Progress of Pharmacovigilance, Significance of Safety Monitoring, Pharmacovigilance in India And International Aspects, WHO International Drug Monitoring Programme, WHO and Regulatory Terminologies of ADR, Evaluation of Medication Safety, Establishing Pharmacovigilance Centres in Hospitals, Industry and National Programmes Related to Pharmacovigilance, Roles and Responsibilities in Pharmacovigilance, International Non-Proprietary Names for Drugs, International Classification of Diseases, Passive and Active Surveillance, Comparative Observational Studies, Targeted Clinical Investigations and Vaccine Safety Surveillance, Aris G Pharmacovigilance, VigiFlow, Statistical Methods for Evaluating Medication Safety Data
Defined daily dose-DDD
B Pharm, Pharm D and medicine syllabus
Useful for examination and regulatory function information
Useful for Pharmacovigilance interview and medical coding also.
Good Luck and all the best!!!
Interaction & discussion on pharmacy practice, pharmacy practice Dr. Sharad Chand
the general concept of the clinical pharmacy, the talk about the competences, skills, and services of the clinical pharmacists. few important regarding the emerging field in pharmacy.
Role of the pharmacist in medication safety.Subash321
Role of the pharmacist in medication safety. In this you know about the medication safety, medication error & how to prevent medication error. And the role of the pharmacists in medication safety.
The Indo-American Journal of Life Sciences and Biotechnology of the journal uses recommended electronic formats for submitting articles, which helps speed up the overall process.Once an article is submitted, it undergoes an initial rapid screening by the editors of the Scopus indexing Journal.
Pharmacovigilance (PV) is defined as the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem. WHO established its Programme for International Drug Monitoring in response to the thalidomide disaster detected in 1961. Together with the WHO Collaborating Centre for International Drug Monitoring, Uppsala, WHO promotes PV at the country level. At the end of 2010, 134 countries were part of the WHO PV Programme. The aims of PV are to enhance patient care and patient safety in relation to the use of medicines; and to support public health programmes by providing reliable, balanced information for the effective assessment of the risk-benefit profile of medicines.
#NationalPharmacovigilanceWeek2022
Theme: Encouraging Reporting ADR by Consumer
Pharmacovigilance in real Life.ppt
Presented on 16/09/2022 at Bengal School of Technology, Chunchura, Hooghly
Pharmacovigilance at NRSMC for last 2yrs and serial look since dec, 2014 ju...Anindya Banerjee
Comparison of ADR monitoring data over 2 consecutive years
&
A study of ADR monitoring data over 4.7 years in a tertiary care teaching hospital of East India
Pharmacovigilance Activity at NRS Medical College in 2017 and 3 Years of Comp...Anindya Banerjee
Pharmacovigilance Activity at NRS Medical College in 2017 AND 3 Years of Comparative Study under NCC-PvPI, IPC by Patient Safety-Pharmacovigilance Associate Mr. Anindya Banerjee
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Putative role of pharmacist in reporting adr and contributing into the national pharmacovigilance system of india
1. Putative Role of Pharmacist in reporting ADR and
contributing into the national Pharmacovigilance
system of India
Anindya Banerjee
Patient Safety-Pharmacovigilance Associate
Dept of Pharmacology
NRS Medical College & Hospital
And
National Coordination Centre-Pharmacovigilance program of India
Indian pharmacopoeia Commission
Ministry of Health & Family Welfare
Govt of India
2. Pharmacy as a Profession
• A Pharmacist is a custodian of medicines who
handles, prepares, dispenses, distributes, and
provides counseling to patient and other HCPs on
appropriate use of drug.
• To become a Pharmacist a degree of D.Pharm,
B.Pharm and M.Pharm must have to be there
alongwith a registration number from the country.
E.g., Pharmacy Council of India (PCI)
3. Pharmaceutical Care and Pharmacist
The role of pharmacist is an integral part of the
healthcare system. WHO explains pharmaceutical
care as “a philosophy of practice in which the
patient is the primary beneficiary of the
pharmacist’s actions. Pharmaceutical care focuses
on the attitudes, behaviours, commitments,
concerns, ethics, functions, knowledge,
responsibilities and skills of the pharmacist on the
provision of drug therapy with the goal of achieving
definite therapeutic outcomes toward patient health
and quality of life.
-The Word “pharmaceutical care,” coined by C. D.
Hepler and L. M. Strand.
-“Pharmacist”: All efforts of rational prescribing
will be nullified if dispensing is inappropriately
carried out. The Pharmacist is the last person the
patient comes in contact with before leaving the
hospital or health facility.
4.
5. Role of Pharmacist
• The prescription must be read and interpreted
correctly so as to ensure that the right drug is
delivered in the correct dose, correct dosage form,
with clear direction to the right person and that
patient is counselled on the rational use of his/her
drugs.
6. Contd..
• Hospital Pharmacist – who
dispenses prescribed drugs,
procures, keep records,
provides counsel and drug
information to the patients
and other HCPs
• Community Pharmacist -
who Possess a drug outlet
such as retail or wholesale
pharmacy stores where
drugs are sold; dispenses
prescription brought by
patients provides counsel
and information.
7. Newer Concept - role of a Pharmacist
Vijay Venkatraman, et al.: Pharmacist as Pharmacovigilance Practitioner
8. Pharmacist as ADR reporter
Pharmacists have an important
responsibility in monitoring the
ongoing safety of medicines as part
of their professional practice.
A drug needs to be considered as a
concept, with benefit-risk profile,
applied to treat patients through
proven or commonly agreed
measures where benefits outweigh
risks.
Here comes the role of pharmacists on
a global perspective called
Pharmacovigilance.
9.
10. Contd..
• It would be prudent to say pharmacovigilance deals with the
collection of adverse drug reaction (ADR) reports from various
stakeholders responsible for monitoring the safety profile of the
drug.
• Safety can be defined as “relative absence of harm”.
• In pharmacovigilance, safety means collection of reports of adverse
effects of drug. Safety can mean generating data and arriving upon a
solution to decide further usage of drug.
• A Pharmacist must also be involved in the collection of data that
might be useful in longitudinal pharmacoepidemiological studies
11. Opportunity of a Pharmacist as Vigilare
• Pharmacists play a key role in management and prevention of
the adverse events associated with the drug.
• Safety concerns are often considered to be implied when drugs
are approved or authorized.
• The scope has widened now. It includes all safety-related
activity right from the moment humans are first exposed to the
new drug. It should be noted that the pharmacists has an added
advantage of getting in direct contact with the patients.
• hospital pharmacists can play a significant role in ADR
reporting because the most serious adverse drug events occur
in hospitals.
12. Pharmacist under NCC-PvPI, IPC
• Doctors are well aware of disease, and diagnosis in Indian
Perspective.
• Pharmacist knows better about the medicine because of the
knowledge of Pharmacology.
• Because of the lack of knowledge of medicine and proper
identification of an ADR, our country is probably running a
status of under reporting.
• under reporting can be significantly reduced by actively
involving pharmacists in the surveillance of drug safety.
13. Contd..
• The participation of pharmacists especially in a country
like ours, where the unawareness is accounted for the
decline in reporting.
• Negligence of reporting is also considered to be a factor
for the steady dearth in reporting and seen as a major
setback among Indian HCPs.
• PvPI now has a dedicated website with a PvPI toolkit for
the stakeholders. PvPI has launched toll free number
1800-180-3024 to facilitate reporting of Adverse
Reactions.
15. Conclusion
• A pharmacist can perhaps be entrusted as an
effective tool in collection and reporting of ADRs
for they are present at all levels of medical care,
right from community pharmacy to primary
healthcare centers, government hospitals to
corporate hospitals.
• Stay tuned, re-invent yourselves and be prepared.
A budding pharmacist should realize clinical
pharmacy is not just drug-drug, drug-food
interaction, but it is also tracking adverse drug
effects, reducing medication errors, monitoring
patients’ compliance, counseling patients
16. Acknowledgement
• Prof (Dr.) Nina Das, Professor & Head, AMC Coordinator,
Dept of Pharmacology, NRS Medical College & Hospital,
Kolkata.
• Dr. Tania Sur (Kundu), Associate Professor, Causality
Assessment Committee Member, Dept of Pharmacology, NRS
Medical College & Hospital, Kolkata.
• Dr. V. Kalaiselvan, Principal Scientific Officer, NCC-PvPI,
IPC, Ministry of Health & Family Welfare, Govt of India,
Ghaziabad
17. Anindya BanerjeeAnindya Banerjee
Patient Safety- Pharmacovigilance AssociatePatient Safety- Pharmacovigilance Associate
Dept of PharmacologyDept of Pharmacology
NRS Medical College & HospitalNRS Medical College & Hospital
andand
NCC-PvPI, IPCNCC-PvPI, IPC
Ministry of Health & Family WelfareMinistry of Health & Family Welfare
Govt of IndiaGovt of India
email:email: anindyabanerjee1988@gmail.comanindyabanerjee1988@gmail.com