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 Blockage in one of the pulmonary arteries
 Blocking blood flow to the lungs, therefore can
be life-threatening
 deep veins in the legs are common sources of
emboli: external iliac v., femoral v. , popliteal v.
 Emboli travels up the IVC → RA → RV →
pulmonary artery
 Artery gets narrower and emboli traps
 Due to gravity more embolism in the lower
portion of the lung
 ↑ pulmonary vascular pressure = backflow of
blood = ↑ right ventricular pressure = R.H failure
 Affected L.H = ↓ C. output = sympathetic reflex =
↑ HR and vasoconstriction
Pathophysiology
 Obstruction = Ventilation perfusion
mismatch
 Inflammation = cytokines =
bronchoconstriction = deep and frequent
breathing = hypoxemia + respiratory
alkalosis
• Wheezing
• Syncope and delirium
• Rapid or irregular heartbeat
• Lightheadedness or dizziness
• Excessive sweating
• Fever
• Leg pain or swelling, or both,
usually in the calf caused by a
deep vein thrombosis
• Clammy or discolored skin
(cyanosis)
• Orthopedic procedures (hip,
knee replacement);
• Abdominal/pelvic surgery;
• Varicose veins;
• No prophylaxis (anticoagulants
after surgery);
• Obesity;
• Women >30 – using OCP
• Smoking
• Immunodeficiency;
• Malignancy;
• Thrombotic disorders;
 X-rays –
to exclude pneumonia or
pneumothorax.
enlarged pulmonary artery.
Wedge-shaped opacity.
 ECG - tachycardia
 Computer tomography
 V/Q scan
 Pulmonary angiography
 D-meter in the blood
Treatment
Medications:
• Anticoagulants
• Thrombolytics
Surgical:
• Clot removal
• Vein filter
Thank You

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Pulmonary embolism

  • 1.
  • 2.  Blockage in one of the pulmonary arteries  Blocking blood flow to the lungs, therefore can be life-threatening  deep veins in the legs are common sources of emboli: external iliac v., femoral v. , popliteal v.  Emboli travels up the IVC → RA → RV → pulmonary artery  Artery gets narrower and emboli traps  Due to gravity more embolism in the lower portion of the lung
  • 3.
  • 4.  ↑ pulmonary vascular pressure = backflow of blood = ↑ right ventricular pressure = R.H failure  Affected L.H = ↓ C. output = sympathetic reflex = ↑ HR and vasoconstriction Pathophysiology  Obstruction = Ventilation perfusion mismatch  Inflammation = cytokines = bronchoconstriction = deep and frequent breathing = hypoxemia + respiratory alkalosis
  • 5. • Wheezing • Syncope and delirium • Rapid or irregular heartbeat • Lightheadedness or dizziness • Excessive sweating • Fever • Leg pain or swelling, or both, usually in the calf caused by a deep vein thrombosis • Clammy or discolored skin (cyanosis)
  • 6. • Orthopedic procedures (hip, knee replacement); • Abdominal/pelvic surgery; • Varicose veins; • No prophylaxis (anticoagulants after surgery); • Obesity; • Women >30 – using OCP • Smoking • Immunodeficiency; • Malignancy; • Thrombotic disorders;
  • 7.  X-rays – to exclude pneumonia or pneumothorax. enlarged pulmonary artery. Wedge-shaped opacity.  ECG - tachycardia  Computer tomography  V/Q scan  Pulmonary angiography  D-meter in the blood

Editor's Notes

  1. Pulmonary embolism is a blockage in one of the pulmonary arteries in your lungs. In most cases, pulmonary embolism is caused by blood clots that travel to the lungs from deep veins in the legs or, rarely, from veins in other parts of the body (deep vein thrombosis). Because the clots block blood flow to the lungs, pulmonary embolism can be life-threatening.
  2. Shortness of breath. This symptom typically appears suddenly and always gets worse with exertion. Chest pain. You may feel like you're having a heart attack. The pain is often sharp and felt when you breathe in deeply, often stopping you from being able to take a deep breath. It can also be felt when you cough, bend or stoop. Cough. The cough may produce bloody or blood-streaked sputum.