This document provides information about live cell therapy and stem cell nutrition therapy presented by Dr. Shebendra. It discusses what live cell therapy and stem cells are, and how stem cell nutrition therapy works by providing less cooked foods, green foods, herbal foods, herbal medicinal foods and herbal medicines. The document also describes the products Astashine Silver and OptiGision Gold, including their active ingredients like astaxanthin and L-carnitine-L-tartrate. It discusses the benefits of these ingredients for antioxidant support, weight management, male fertility, cardiovascular health and more. Finally, it provides details on olive leaf extract and broccoli extract ingredients.

1. Honorary PhD,IUM-USA
Astashine
silver
&
OptiGision Gold
PUGOS
Presentation
Presented by
Dr.Shebendra
Honorary PhD
IUM-USA

2. Live CellTherapy
Cell Health management with NaturalWay

3. What is live cell therapy?
Cell Live therapy helps to repair and regenerate
human body Cell, and therefore enhances
immunity.
Cell degeneration causes ageing in human,
therefore by delivering energy from live cells to
ageing cells, it keeps human body young and
healthy.

4. Cell is tiny life.
Our body
comprises of 100
trillion of cells.

8. Picture of a high quality expanded human blastocyst embryo 5 days after fertilization
The clump of cells in the 10 to 12 o'clock area is the inner cell mass (ICM) which become the fetusThe
trophectoderm cells (TE) that will form the placenta surround the fluid cavity
The fluid-filled blastocoel cavity is in the center

11. What is stem cell?

14. All the body cell same to look , same Biological function , only different execution

16. Stem Cell needs only
Plant Chemicals
Only Plants produce
Plant Chemicals for
Stem Cell

17. All Plants of the nature synthesis & contain the following
Plant Chemicals
1.Amino acid
2.Glucose
3.Fatty acid
4.Vitamins
5.Minerals
6.Water
Alphabets of Plant

18. All Animals of the nature contain the following
Plant Chemicals
1.Amino acid
2.Glucose
3.Fatty acid
4.Vitamins
5.Minerals
6.Water
Alphabets of Animal

19. Plant & Animal Comprises of same
Plant Chemicals
 Plants
 1.Amino acid
 2.Gluclose
 3.Fatty acids
 4.Vitamins
 5.Minerals
 6.Water
 Animals
 1.Amino acid
 2.Gluclose
 3.Fatty acids
 4.Vitamins
 5.Minerals
 6.Water

21. Only Plants compose Biochemical .
Animals (Human) eat Plants
We can say:
Six plant Chemicals are common
Alphabets & Bricks of Plants & Animals.

22. Well come to
A thinking of Modern Medication
By applying
StemCell Nutrition

23. StemCell NutritionTherapy will start
By providing :
1. Less Cooking Food 20%
2. Green Food 60%
3. Herbal Food
4. Herbal Medicinal Food
5. Herbal Medicine

24. OUR PRODUCTS

25. ASTASHINE SILVER
A natural antioxidant and a conditionally essential vitamin like
nutrient that helps to re-energize your cells.

26. AstaReal’s Astaxanthin in ASTASHINE Silver
Astareal in Astashine contains natural astaxanthin from the microalgae,
Haematococcus pluvialis, and a natural carotenoid that can be found from arctic
marine environments, to common fresh water rock pools throughout the world.
Astareal in ASTASHINE Silver contains natural astaxanthin from the microalgae,
Haematococcus pluvialis, and a natural carotenoid that can be found from arctic
marine environments, to common fresh water rock pools throughout the world.
Astaxanthin is what gives the pink and red color to salmon, shrimp and lobster.
In the natural environment, animals depend on their diet to obtain astaxanthin
and other carotenoids since they cannot produce carotenoids themselves. The
most abundant source of astaxanthin in nature is Haematococcus pluvialis,
which will accumulate astaxanthin in lipid vesicles during periods of nutrient
deficiency and environmental stress. Because Haematococcus often grows in
places that are exposed to intense sunlight during its dormant phase,
astaxanthin functions to protect the cell nucleus against free radicals generated
by UV radiation that would otherwise cause damage to its DNA and peroxides
energy reservoirs.
Natural astaxanthin has a unique molecular structure that makes it literally
hundreds of times stronger than any other antioxidant molecule. For this
reason, astaxanthin is often called “The King of Antioxidants”.

27. Carnipure’s L-Carnitine-L-Tartrate in ASTASHINE Silver
Carnipure’s L- Carnitine-L-Tartrate is high quality special grade L-carnitine
manufactured by Lonza, Switzerland. It is a salt of 68% L- Carnitine and 32%
tartaric acid, which is highest L-Carnitine concentration of any commercially
available hygroscopic salt form. L- Carnitine-L-Tartrate in ASTASHINE Silver is
heat and pH stable.
L-Carnitine is a vitamin like nutrient related to vitamins of B group. L-Carnitine is
a physiological substance, essential for energy production and for fat metabolism.
L-Carnitine can be synthesized in the human liver and kidney, but insufficient
amount may be produced in infants, in adolescents and in adults under certain
physiological conditions.
L-Carnitine is supplied to the human body via both food intake and endogenous
synthesis (we can make it ourselves in our bodies). Dietary sources of L-Carnitine
are confined mainly to foods of animal origin, particularly red meat (this obviously
has important implication for vegetarians) and dietary L-Carnitine is absorbed in
the small intestine. Endogenous synthesis requires six other nutrients, including
amino acids, vitamins and iron .L-Carnitine synthesis takes place primarily in the
liver and kidney. The skeletal muscle and the heart, which depend upon fat
breakdown for energy, are highly dependent on L-Carnitine transport from the
site of synthesis.

29. Fatty Acid Oxidation
Carnipure’s L-Carnitine in ASTASHINE Silver helps the
body, use fat for energy generation. This process is called
“fatty acid metabolism, or beta oxidation”, and takes
place within the mitochondrial matrix of a cell. In order
for fatty acids to be metabolized into energy, they must
be transported across the mitochondrial membrane. L-
carnitine is the transport molecule to bring fatty acids
into the matrix. In order to be transported into the
matrix, fatty acids must be activated. This activation
involves a fatty acid, sometimes referred to as an acyl
group, combining with a compound called co-enzyme A,
or CoA. When the fatty acid has been activated, it is then
referred to as acyl-CoA. This is the compound that L-
carnitine joins with to form acyl-L-carnitine. The process
of shuttling acyl-L-carnitine across the mitochondrial
membrane involves three different enzymes. They are
Carnitine palmitoyltransferase (CPT1), Carnitine acyl
translocase (CT) and Carnitine palmitoyltransferase
(CPT2). CPT1 is considered the rate limiting step to fatty
acid oxidation because it is tightly regulated by malonyl
CoA10. Malonyl CoA and L-carnitine both compete for
binding sites on CPT1.

30. CoenzymeA Regulation
Another function of L-carnitine is
related to regulating coenzyme A in the
mitochondria. CoA is an important co-
factor for many energy producing
metabolic pathways. L-carnitine helps
increase the amount of free CoA
available in the mitochondria. For
example, when L-carnitine binds to
acyl-CoA for fatty acid metabolism, the
CoA group is free and can participate in
other energy producing pathways. In
another example of this regulation
function, L-carnitine can also bind to
acetylCoA. In this case, acetyl-L-
carnitine forms and CoA is released into
the mitochondria1. Free CoA is again
able to join other pathways, such as the
oxidative metabolism of glucose.

31. Detoxification
Detoxification is the third major metabolic function of L-carnitine. Certain compounds form
toxic by-products which need to be removed from the body. L-carnitine can help in these
situations by binding to the toxic substance.This is then excreted by the body.
For example, during heavy exercise, individuals excrete excess metabolic waste through ester
formation with L-carnitine.
In another example, patients on long term treatment with certain xenobiotics, or prodrugs,
such as pivalic acid, use L-carnitine to remove toxic by-products. Over 90 percent of
administered pivalic acid is eliminated from the body in the form of pivalonyl carnitine. Long
term use of those types of drugs, however, may lead to decreased plasma levels of L-carnitine
and subsequently to secondary L-carnitine deficiency.

32. Role of L-Carnitine on
Weight Management
Helps to support the conversion of
fat into metabolic energy.
Helps to increase beta-oxidation,
sparing glucose and decreases
breakdown of amino acids.
Helps to decrease fat mass by
preserving muscle mass.
Helps to decrease physical and
mental fatigue.

33. Role of L-carnitine on
Male Fertility
Helps to increase sperm count, quality,
motility and maturation.
Helps to increase energy metabolism and
supports sperm quality.
Helps to increase antioxidant enzymes
such as haemeoxygenase-1 and
endothelial nitric oxide synthetase.
Helps to increase the percentage of
sperm with rapid progression.

34. Role of L-Carnitine on
Cardiovascular Health
Helps to regulate heart arrhythmia.
Helps to increase heart muscle viability.
Helps to improve lipid metabolism and
antioxidant status.
L- Carnitine is an important energy provider
for the heart.

35. BenefitsHelps to improve blood lipid profile.
Helps to decrease muscle soreness by improving recovery time.
Helps to decrease fat mass by preserving muscle mass
Helps to support the conversion of fat into metabolic energy.
Helps to increase sperm count, quality, motility and maturation.
Helps to increase energy metabolism and supports sperm quality
Helps to reduce lipid per oxidation and oxidative stress.
Helps to reduce the size of wrinkles, improves skin’s micro texture,
elasticity and smoothness.
Helps to improve Eye Fatigue, Weak Vision and Shoulder stiffness.
Helps to improve Heart health, Cellular health and Body’s Immune system.
Helps to increase energy metabolism in Elderly people.
Helps to reduce lipid oxidative metabolism there by limits muscle aging.
Helps to enhance the capacity of RBC, lymphocytes and Phagocytes.

36. Supplement Facts
Presentation: 60 capsules
Usage: As a food supplement combination of antioxidants to improve health
and vitality.
Recommended usage : Adults: two capsules per day along with food.
“Do not exceed the recommended daily dose”
“Food supplements must not be used as a substitute for a varied and
balanced diet and a healthy lifestyle”
“This product is not intended to diagnose, treat, cure or prevent any
disease(s)”
Administration: Taken by oral route at anytime with food.
Precautions: Food Supplements must not be used as a substitute for a varied
and balanced diet and a healthy lifestyle. This Product is not intended to
diagnose, treat, cure or prevent any diseases. Do not exceed the
recommended daily dose.
Warnings: If you are taking any prescribed medication or has any medical
conditions or have any medical conditions (seizures) under age group 17 year
always consults doctor or healthcare practitioner before taking supplements.
Side Effects: Mild side effects like nausea, headache and vomiting in some
individuals have been reported.
Storage: Store in a cool, dry and dark place.
Keep out of reach of children.

37. Global Preferred Partnership with
AstaReal
The world’s leading producer and innovator of natural
astaxanthin. AstaReal Inc. is part of the AstaReal
Group which is a wholly owned subsidiary of Fuji
Chemical Industries Co., Ltd. Astareal’s natural
astaxanthin is cultivated, grown and harvested at
manufacturing facility in Moses Lake, Washington. As
the global demand for natural astaxanthin continues
to grow, they are fully dedicated in ensuring the
supply of premium, natural astaxanthin products.
Carnipure L-Carnitine-L-Tartrate In ASTASHINE
Silver by Lonza, Switzerland.
Founded in 1897 in the Swiss Alps, is a well-respected global
company with more than 40 major manufacturing and R&D
facilities. Lonza is one of the world’s leading and most-trusted
suppliers to the Pharma, Healthcare and life science industries.
Carnipure’s L- carnitine by lonza is the biggest supplier of L-
Carnitine with more than 30 years of research in various
clinical studies and continued scientific support.

39. PUGOS Products Pvt. Ltd.
INGREDIENTS
DETAILS
Olive Leaf
Extract

40. INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
Olive Leaf
Extract
The phenolic compounds present in olive
leaves, especially oleuropein, have been
found to have therapeutic effects for
many conditions including high blood
pressure, diabetes, obesity, Alzheimer’s,
and heart disease.
It’s even known to prevent genetic damage
and cancer growth. If you suffer from any of
these conditions, find out how olive leaf
extracts can help you!

41. PUGOS Products Pvt. Ltd.
INGREDIENT
S DETAILS
Olive Leaf
Extract
• Olive Leaf Extract has an
 Anti-oxidant
 Anti-hypertensive
 Anti-atherogenic
 Anti-inflammatory
 Hypercholesterolemia
 Hypoglycemic properties.

42. Benefits of Olive Leaf Extract
1) Olive Leaf Extract Lowers Blood Pressure:
In a study of men with high blood pressure. It also lowered fat and cholesterol
levels in the blood. In patients with high blood pressure, taking 500 mg of
oleuropein twice a day for 8 weeks effectively lowered both systolic and diastolic
blood pressure.
2) Olive Leaf Extract Improves Cardiovascular Health
In both a rat model and in cell study of heart damage caused by oxidative stress,
olive leaf extracts prevented the death of heart cells and maintained
mitochondrial functions
3) Olive Leaf Extract Prevents Cancer and Protects DNA
Many studies support the idea that phenolic compounds, such as those found in
olive leaf extract, play an important role in preventing cancer.
A recent study shows that olive leaf extract kills bone cancer cells and prevents
them from multiplying.
Olive Leaf
Extract
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.

43. Benefits of Olive Leaf Extract
4) Olive Leaf Extract is Anti-Diabetes
In a rabbit model of diabetes, oleuropein lowered and restored normal
blood glucose levels and MDA. In a study of rats induced with diabetes,
leuropein reduced body weight, fat tissue mass, and liver fat. It
improved insulin sensitivity and increased the uptake of blood sugar in
mouse models of diabetes.
5) Olive Leaf Extract is Anti-Obesity
It seems that olive leaf extract can help fight obesity by preventing the
body from generating more fat cells
6) Olive Leaf Extract Preserves Nurvous Protection
Even in the late-stages of Alzheimer’s, mice experienced improved brain
cell function after being treated with oleuropein aglycone. This suggests
that olive leaf extract can be used not only as a preventative measure but
also as a therapeutic treatment
Olive Leaf
Extract
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.

44. Benefits of Olive Leaf Extract
7) Olive Leaf Extract is Anti-Inflammatory
In a study of mice injected with cisplatin to induce kidney damage,
oleuropein countered the damaging effects of cisplatin.Oleuropein
lowered creatinine and blood urea nitrogen to normal levels.
Oleuropein also reduced inflammation and prevented kidney cell
death
8) Olive Leaf Extract is Antibacterial,
Antifungal, Antiphrastic
Olive leaf extract has been tested for antibacterial action against
lactic acid bacteria. Oleuropein was not inhibitory, but two of its
hydrolysis products, the aglycone, and oleanolic acid inhibited
growth of the four species of lactic acid bacteria tested
Olive Leaf
Extract
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.

45. Benefits of Olive Leaf Extract
9) Olive Leaf Extract is an Antioxidant
In an experiment with mice poisoned by arsenic, oleuropein reduced
oxidative damage in blood, liver, kidney, and brain tissues
10) Improves Bone Density and Prevents Bone
Loss
Studies suggest that olive tree products could prevent age-related
bone loss.
A study on human bone marrow stem cells found that
oleuropein increased bone cell production.
In mice whose ovaries were removed, talc-induced inflammation
increased bone loss and loss of bone density. However, olive oil and
its main polyphenol oleuropein prevented this bone lossOlive Leaf
Extract
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.

46. PUGOS Products Pvt. Ltd.
INGREDIENTS
DETAILS
BROCCOLI
Extract

47. OUR
PRODUCTS
PUGOS Products Pvt. Ltd.
BROCCO
LI
Extract

48. PUGOS Products Pvt. Ltd.
INGREDIENT
S DETAILS
BROCCOLI
Extract

49. PUGOS Products Pvt. Ltd.
INGREDIENTS
DETAILS
Berberis
Aristata
Extract
Berberis aristata, also known as Indian barberry,
"chutro" or tree turmeric, is a shrub belonging
to the family Berberidaceae and the
genus Berberis. The genus comprises
approximately 450-500 species of deciduous
evergreen shrubs and is found in the temperate
and sub-tropical regions of Asia, Europe, and
America. B. aristata is native to
the Himalayas in India and in Nepal. It is also
naturally found in the wet zone of Sri Lanka.

50. PUGOS Products Pvt. Ltd.
INGREDIENTS
DETAILS
Berberis
Aristata
Extract

51. PUGOS Products Pvt. Ltd.
INGREDIENTS
DETAILS
Berberis
Aristata
Extract
Berberine is the most prominent of these
alkaloids and according to laboratory
studies, it has an antimicrobial, anti
inflammatory, hypotensive, sedative,
and anticonvulsant effect.

52. PUGOS Products Pvt. Ltd.
INGREDIENTS
DETAILS
Rose Hip
Extract

53. Rose Hip
Extract

54. PUGOS Products Pvt. Ltd.
INGREDIENTS
DETAILS
Carica Papaya
Leaf Extract

55. PUGOS Products Pvt. Ltd.
INGREDIENTS
DETAILS
Carica Papaya
Leaf Extract

56. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
C HLORELLA
Extract

57. INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
CHLORELLA
Extract

58. OUR PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
CHLORELLA
Extract
Chlorella is a blue-green algae like its
cousin Spirulina. Studies have shown that
chlorella benefits the entire body by supporting
healthy hormonal function,
promoting cardiovascular health, helping to
negate the effects of chemotherapy and
radiation, lowering blood pressure and
cholesterol, and aiding in the detoxification of
our bodies. Chlorella’s rich green color comes
from a high concentration of chlorophyll.

59. OUR PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
CHLORELLA
Extract
Chlorella Nutrition Facts
As you’re about to see, chlorella is one of the
most nutrient-dense superfoods in the world.
A 1-ounce (3 tbsp) serving of chlorella contains:
Protein—16g
Vitamin A—287% RDA
Vitamin B2—71% RDA
Vitamin B3—33% RDA
Iron—202% RDA
Magnesium—22% RDA
Zinc—133% RDA

60. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
CHLORELLA
Extract

61. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
SHILAJIT
Extract

62. OUR PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.

63. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
SHILAJIT
Extract

64. INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
AMLA
Extract

65. INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
AMLA
Extract

66. INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
AMLA
Extract
Benefits Of Amla (Indian Gooseberry)

67. INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
AMLA
Extract
Benefits Of Amla (Indian Gooseberry)

68. INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
Guava
Extract
Benefits Of Amla (Indian Gooseberry)

69. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
Guava
Extract
Benefits Of Amla (Indian Gooseberry)

70. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
SESBANIA
Extract
Benefits Of Amla (Indian Gooseberry)

71. INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
SESBANIA
Extract
Benefits Of SESBANIA

72. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
HOLY BASIL
Extract

73. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
HOLY BASIL
Extract

74. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
CITRUS
BIOFLAVONOIDS

75. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
CITRUS
BIOFLAVONOIDS

76. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
PIPERINE
EXTRACT

77. OUR
PRODUCTS
PIPERINE
EXTRACT

78. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
GINSENG
EXTRACT

79. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
GINSENG
EXTRACT

80. OUR
PRODUCTS
INGREDIENTS DETAIL PUGOS Products Pvt. Ltd.
GINKGO
BILOBA
EXTRACT

81. OUR
PRODUCTS
GINKGO
BILOBA
EXTRACT

82. OUR
PRODUCTS
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.
ASPARAGUS
ADSCENDENS
EXTRACT

83. OUR
PRODUCTS
ASPARAGU
ADSCENDENS
EXTRACT

84. OUR
PRODUCTS
GINGER
EXTRACT
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.

85. OUR
PRODUCTS
GINGER
EXTRACT

86. OUR
PRODUCTS
GREEN
COFFEE
BEAN
EXTRACT
INGREDIENTS DETAILS PUGOS Products Pvt. Ltd.

87. OUR
PRODUCTS
GREEN
COFFEE
BEAN
EXTRACT

88. Health Benefits of
OptiGision Gold

89. Health Benefits of
OptiGision Gold

90. Health Benefits of
OptiGision Gold

91. Thank you all for giving attention
Presented by:
Dr. Shebendra karmakar
PhD in Natural Medicine,USA
Honorary PhD, IUM-USA
Sun Badges ,Khan Academy, USA
(Biology, Medicine & Health)