Just regarded to those who trying to learn somethings.. . thanks to those who read this slide... Just pray for me , for my parents and for my teachers...
Just regarded to those who trying to learn somethings.. . thanks to those who read this slide... Just pray for me , for my parents and for my teachers...
in this presentation, the light is focused on discussing the Reactive oxygen species, oxidative stress, how it forms, how it affects the body and what are the diseases that correlate with oxidative stress.
nevertheless, how it can be balanced by the antioxidants and what is their role in oxidative stress.
Antioxidants are molecules capable of reducing the causes or effects of oxidative stress. Oxidative stress can be caused by environmental factors, disease, infection, inflammation, aging (ROS production). The body produces some endogenous antioxidants, but dietary antioxidants may provide additional line of defense. Flavonoids & other polyphenolics, Vitamins C & E, and Carotenoids are the most common dietary antioxidants. Many herbs and botanicals also contain antioxidants.
Any molecule containing one or more unpaired electrons. These unpaired electrons readily form free radical molecules which are chemically reactive and highly unstable.
Oxidative Stress in Aging and Human Diseases - Exploring the MechanismsQIAGEN
Many modern diseases, including cancer, cardiovascular disease, diabetes, liver disease, arthritis and neurodegenerative disease are related to aging, and aging is closely linked to oxidative stress. Intensive research is being conducted to understand the antioxidant defense mechanism, the mechanisms of aging itself, as well as their roles in human diseases. This slidedeck provides an update on how oxidative stress is linked to aging and how inflammation leads to aging through DNA damage, telomere dysfunction, cellular senescence and oxidative stress. Recent progress on the health benefits of antioxidants and examination of their potential mechanisms in the prevention and treatment of chronic diseases are also covered. Various assay technologies to tackle the complex signaling pathways in this process will be introduced. Learn how you can apply these advanced tools to your research!
An antioxidant is a molecule capable of inhibiting the oxidation of other molecules.
Oxidation reactions can form free radicals and these start chain reactions that damage cells .
Antioxidants terminate these chain reactions by removing free radical intermediates and inhibit other oxidation reactions
Antioxidants - protective activity of certain important antioxidantsAYESHA NAZEER
Introduction to free radicals, antioxidants, types of antioxidants, biological importance and protective role of certain important antioxidants in diseases.
in this presentation, the light is focused on discussing the Reactive oxygen species, oxidative stress, how it forms, how it affects the body and what are the diseases that correlate with oxidative stress.
nevertheless, how it can be balanced by the antioxidants and what is their role in oxidative stress.
Antioxidants are molecules capable of reducing the causes or effects of oxidative stress. Oxidative stress can be caused by environmental factors, disease, infection, inflammation, aging (ROS production). The body produces some endogenous antioxidants, but dietary antioxidants may provide additional line of defense. Flavonoids & other polyphenolics, Vitamins C & E, and Carotenoids are the most common dietary antioxidants. Many herbs and botanicals also contain antioxidants.
Any molecule containing one or more unpaired electrons. These unpaired electrons readily form free radical molecules which are chemically reactive and highly unstable.
Oxidative Stress in Aging and Human Diseases - Exploring the MechanismsQIAGEN
Many modern diseases, including cancer, cardiovascular disease, diabetes, liver disease, arthritis and neurodegenerative disease are related to aging, and aging is closely linked to oxidative stress. Intensive research is being conducted to understand the antioxidant defense mechanism, the mechanisms of aging itself, as well as their roles in human diseases. This slidedeck provides an update on how oxidative stress is linked to aging and how inflammation leads to aging through DNA damage, telomere dysfunction, cellular senescence and oxidative stress. Recent progress on the health benefits of antioxidants and examination of their potential mechanisms in the prevention and treatment of chronic diseases are also covered. Various assay technologies to tackle the complex signaling pathways in this process will be introduced. Learn how you can apply these advanced tools to your research!
An antioxidant is a molecule capable of inhibiting the oxidation of other molecules.
Oxidation reactions can form free radicals and these start chain reactions that damage cells .
Antioxidants terminate these chain reactions by removing free radical intermediates and inhibit other oxidation reactions
Antioxidants - protective activity of certain important antioxidantsAYESHA NAZEER
Introduction to free radicals, antioxidants, types of antioxidants, biological importance and protective role of certain important antioxidants in diseases.
Antioxidants can prevent or slow cell damage caused by free radicals. Free radicals are unstable molecules that the body produces as a reaction to environmental and other pressures. They can increase the risk of inflammation and various health issues.
They are sometimes called “free-radical scavengers.”
The sources of antioxidants can be natural or artificial. Certain plant-based foods are thought to be rich in antioxidants. Plant-based antioxidants are a kind of phytonutrient, or plant-based nutrient.
The body also produces some antioxidants, known as endogenous antioxidants. Antioxidants that come from outside the body are called exogenous.
Free radicals are waste substances produced by cells as the body processes food and reacts to the environment. If the body cannot process and remove free radicals efficiently, oxidative stress can result. This can harm cells and body function. Free radicals are also known as reactive oxygen species (ROS).
Factors that increase the production of free radicals in the body can be internal, such as inflammation, or external, for example, pollution, UV exposure, and cigarette smoke.
Oxidative stress has been linked to heart disease, cancer, arthritis, stroke, respiratory diseases, immune deficiency, emphysema, Parkinson’s disease, and other inflammatory or ischemic conditions.
Antioxidants are said to help neutralize free radicals in our bodies, and this is thought to boost overall health.
Antioxidants can protect against the cell damage that free radicals cause, known as oxidative stress.
Activities and processes that can lead to oxidative stress include:
mitochondrial activity
excessive exercise
tissue trauma, due to inflammation and injury
ischemia and reperfusion damage
consumption of certain foods, especially refined and processed foods, trans fats, artificial sweeteners, and certain dyes and additives
smoking
environmental pollution
radiation
exposure to chemicals, such as pesticides and drugs, including chemotherapy
industrial solvents
ozone
Free radicals are very unstable and react quickly with other compounds, trying to capture the needed electron to gain stability.
Generally, free radicals attack the nearest stable molecule, "stealing" its electron.
When the "attacked" molecule loses its electron, it becomes a free radical itself, beginning a chain reaction.
Once the process is started, it can cascade, finally resulting in the disruption of a living cell.
LYCOTENFORTE CapsulesTM: The most powerful antioxidant mentains optimum healt...SriramNagarajan16
Oxidation is a chemical reaction that transfers electrons from a substance to anoxidizing agent Oxidation
reactions can produce free radicals. In turn, these radicals can start chain reactions.
Antioxidants terminate the chain reactions by removing free radical intermediates, and inhibit other oxidation
reactions. They do this by being oxidized themselves, so antioxidants are often called as reducing agents such
as thiols, ascorbic acid or polyphenols.
Antioxidants are widely used as ingredients in dietary supplements and have been investigated for the
prevention of diseases such as cancer, coronary heart disease and even altitude sickness.
Antioxidants are our first line of defense against free radical damage, and are critical for maintaining optimum
health and wellbeing. The need for antioxidants becomes even more critical with increased exposure to free
radicals. Pollution, cigarette smoke, drugs, illness, stress, and even exercise can increase free radical exposure.
Because so many factors can contribute to oxidative stress, individual assessment of susceptibility becomes
important. Many experts believe that the Recommended Dietary Allowance (RDA) for specific antioxidants
may be inadequate and, in some instances, the need may be several times the RDA. As part of a healthy lifestyle
and a well-balanced, wholesome diet, antioxidant supplementation is now being recognized as an important
means of improving free radical protection. Damage to cells caused by free radicals is believed to play a central
role in the aging process and in disease progression. The present paper Reviews the Role of LYCOTENFORTE
Capsules in maintaining optimum health and wellbeing.
Free radicals are electron missing atoms or molecules. It is very unstable and react quickly with other compounds, trying to capture the needed electron to gain stability.
Generally, free radicals attack the nearest stable molecule, "stealing" its electron.
When the "attacked" molecule loses its electron, it becomes a free radical itself, beginning a chain reaction like snowball.
Once the process is started, it can cascade, finally resulting in the disruption of a living cell. The rule of antioxidants is to give electrons to free radicals and neutralize its destructive effects especially on the DNA.
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In the heart of Singapore, where tradition meets modernity, He embarks on a culinary adventure that transcends borders. His mission? Ang Chong Yi Exploring the Cultural Heritage and Identity in Singaporean Cuisine. To explore the rich tapestry of flavours that define Singaporean cuisine while embracing innovative plant-based approaches. Join us as we follow his footsteps through bustling markets, hidden hawker stalls, and vibrant street corners.
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1. Dr. Sudha Tiwari,
Asst. Professor
Department of Health & Paramedical Sci,
PSS Central Institute of Vocational Education,
NCERT, Bhopal
2. ANTIOXIDANTS
Antioxidants are man-made or natural
substances that may prevent or delay some
types of cell damage caused by free radicals,
unstable molecules that the body produces as
a reaction to environmental and other
pressures.
They are sometimes called “free-radical
scavengers.”
The sources of antioxidants can be natural or
artificial.
4. FREE RADICALS
Free radicals are waste substance
produced by cells as the body processes
food and reacts to the environment.
If the body cannot process and remove
free radicals efficiently, oxidative stress
can result.
This can harm cells and body function.
Free radicals are also known as reactive
oxygen species (ROS).
5.
6. Oxidative Stress
Factors that increase the production of free
radicals in the body can be internal, such
as inflammation or external, for example,
pollution, UV exposure, and cigarette smoke.
Oxidative stress has been linked to heart
disease, cancer, arthritis, stroke, respiratory
diseases, immune deficiency, emphysema,
Parkinson’s disease and other inflammatory
or ischemic conditions.
8. ANTIOXIDANTS
The keyword here is variety.
Try to get as many fruits
and vegetables with different
colors when you plan your
meals and go to the grocery
store.
An array of color in your
diet will give you the widest
range of beneficial
antioxidants.
10. Exogenous Anti-oxidants
Antioxidants that come from outside the body
are called exogenous antioxidants.
Certain plant-based foods are thought to be
rich in antioxidants. Plant-based antioxidants
are a kind of phytonutrient, or plant-based
nutrient.
Examples of exogenous antioxidants include
vitamins(C,E),minerals(Se, Cu, Zn, Mn) and
phytochemicals such as carotenoids,
lycopene, lutein, and zeaxanthin.
12. VITAMIN C
Best-known antioxidant offers a wide-variety
of health benefits which include protecting
body from infection and damage to body cells,
helping produce collagen and helping in the
absorption of iron.
Ascorbic acid is a redox catalyst which can
reduce, and thereby neutralize, reactive
oxygen species such as hydrogen peroxide.
It is maintained in its reduced form by
reaction with glutathione, which can be
catalysed by protein disulfide
isomerase and glutaredoxins.
14. Vitamin E
Vitamin E is the collective name for a set of
eight related tocopherols and tocotrienols
which are fat-soluble vitamins
Vitamin E works with other antioxidants such
as vitamin C to offer protection from some
chronic diseases.
Protects body from cell damage that can lead to
cancer, heart disease and cataracts as we age.
Vitamin E is found in vegetable oils, wheat
germ, whole-grains and fortified cereals, seeds,
nuts and peanut butter.
16. Mineral Anti-oxidants- Selenium
Selenium is a powerful
antioxidant that may
help protect the heart
and body from
developing certain
types of cancer.
Foods high in selenium
include: Brazil nuts ,
Yellow fin tuna,
Halibut ,Sardines, in
oil with bones , Ham,
barley, brown rice
17. Zinc- Anti-oxidant Mineral
Zinc act as instrumental
in the activity of about
100 enzymes in the
body.
Among its known anti-
inflammatory powers is
protection of the
arteries.
Zinc: Beef, poultry,
oysters, shrimp, sesame
seeds,
pumpkinseeds, chickpea
s, lentils, cashews,
fortified cereals
18. COPPER
It act as a pro-oxidant (causes
free radical damage) and an antioxidant.
Copper is composed of a powerful antioxidant
enzyme and ceruloplasmin, a protein
responsible for transporting iron to your tissues.
Not getting enough copper affects the levels of
selenium, iron, catalase, and glutathione — all
powerful antioxidants.
Foods high in copper include: Oysters, Black
beans, Soy protein powder, Granola, Tomato
puree
19. MANGANESE
Like copper, manganese is
a powerful antioxidant.
Manganese superoxide
dismutase (MnSOD) is the
main antioxidant enzyme
in the mitochondria of
every cell in the body.
Foods highest in
manganese are: Pecans
Brown rice, Pineapple ,
Almonds , Pineapple juice
20. IRON
This nutrient helps protect the cell membrane
from damage (oxidation).
It’s found in two forms: iron connected to a
special protein that helps with absorption
(heme) and one without the attached protein
(nonheme).
Nonheme iron is found in plant foods and
fortified foods, while meat, seafood, and poultry
contain both nonheme and heme iron. (18)
Foods high in iron include: Oysters,White
beans, Dark chocolate, Beef liver
22. PHYTONUTRIENTS
These are chemical compounds found in
plants, and they have a variety of possible
health benefits for the body, including
antioxidant activity.
Flavonoids, flavones, catechins, polyphenols,
and phytoestrogens are all types of
antioxidants and phytonutrients, and they are
all found in plant-based foods.
Each antioxidant serves a different function
and is not interchangeable with another. This
is why it is important to have a varied diet.
Phenolic compounds: Quercetin catechins
resveratrol coumaric acid, anthocyanins.
25. BETA-CAROTENE
Among the 600 or more carotenoids in foods,
lycopene and lutein are well-known leaders in
the fight to reduce the damage from free
radicals.
Carotenoids may be effective in helping
prevent certain cancers and may help decrease
your risk of macular degeneration.
Carotenoids including beta-carotene and
lycopene: Apricots, asparagus, beets, broccoli,
cantaloupe, carrots, bell peppers, kale,
mangos, turnip and collard greens, oranges,
peaches, pink grapefruit, pumpkin, winter
squash, spinach, sweet potato, tangerines,
tomatoes, and watermelon.
26.
27. Anthocyanins -These are found in blue
and purple fruits and veggies, such as
berries, eggplant, purple potatoes,
carrots, and asparagus. These
antioxidants help promote blood vessel
health.
Resveratrol - They have been shown to
help promote heart and lung health, help
prevent certain types of cancer, and
reduce inflammation overall. This type of
antioxidant is found dark chocolate, red
wine, peanuts, and grapes.
28. Isoflavones-They’re found in soybeans.
They may help promote bone health,
decrease joint inflammation, ease
menopause symptoms, and help protect
against breast cancer.
Lycopene -This is found in tomatoes and
tomato
products,pink grapefruit, watermelon and
red peppers. These help promote prostate
and heart health.
29. Lutein - This antioxidant is found in
spinach, Brussels sprouts, broccoli,
lettuce, kale, artichokes, and collard
greens. This antioxidant can help
promote eye and heart health and
may play a role in preventing some
cancers.
This one is the precursor to vitamin A
and this antioxidant is high in orange
produce items.
31. Endogenous Enzymes as Anti-oxidants
Superoxide dismutases (SODs) These are the
major antioxidant defense system against free
radicals. Formed in the body, they do require
copper and manganese to make them work.
Glutathione peroxidase (GSHPx) This is a cell
antioxidant enzyme that reduces hydrogen
peroxide to water. Selenium is part of the
regulation and translation which means it is a
required mineral for this enzyme to activate.
Catalase (CAT) This is also responsible for
changing hydrogen peroxide to water using
iron as its assistant (called a cofactor).
32. Does it Matter Whether the food is Cooked or
Consumed Raw?
Depending on the particular food, cooking
temperatures and methods can sometimes
increase or decrease antioxidant levels. The
important thing is that you eat antioxidant-
rich foods, so go with your personal
preference for preparation—as long as it's not
deep frying!
33. Are added Antioxidants as Effective as those
that occur Naturally?
Yes, vitamins such as C, A and E can be added
to foods – and they often are, such as in orange
juice.
There is no significant physiological difference
between the added antioxidants and the ones
occurring naturally in the food source. However,
there’s also no evidence that taking antioxidant
dietary supplements work as well as the
antioxidants found in food products.
It’s important not to overdo it on supplements
because there can be too much of a good thing.