This document describes a case study of 13 patients with recalcitrant pseudophakic cystoid macular edema (CME) who were treated with intravitreal dexamethasone implants. Before the implants, patients had received topical steroids, NSAIDs, oral carbonic anhydrase inhibitors, and subtenon triamcinolone injections without resolution of CME. After dexamethasone implants, vision improved in all patients and OCT thickness decreased. One patient had recurrence and required a second implant. No patients experienced intraocular pressure spikes. The study concludes dexamethasone implants are a viable treatment for recalcitrant pseudophakic CME.