This is the PowerPoint presentation for students of grade 10. Here you will get a chance to know about the Laws of pressure, liquid pressure, Upthrust, Archimede's Principle, Density and Thermometer. Everything is briefly explained as notes with proper experimental verification, examples, and some other interesting facts about this lesson.
What is the pressure?
What is formulae of pressure?
What is the SI unit of pressure?
What is fluid pressure?
What is atmospheric pressure?
How can we measure pressure?
What is the pressure?
What is formulae of pressure?
What is the SI unit of pressure?
What is fluid pressure?
What is atmospheric pressure?
How can we measure pressure?
This presentation is designed for the students of grades 11 and 12. You can know about the importance and scope of chemistry. Atomic mass, the process of naming compounds, acids, the chemical name of substances, and so on.
This presentation is for the students seeking biology. In these slides, you can learn about zoology and its history. Some important branches of biology and the important contributions made by scientists all over the world in the field of biology.
This is designed for grade 11 students,
This presentation is prepared for the students of grades 11 and 12 concluding the chapter thermodynamics. Proper notes with diagrams, facts, and figures are presented. Numericals are solved too.
This PowerPoint presentation is for Grade 10 students. I have included all the topics in this presentation. Here you can know about Light, Types of lenses, Some terms related to lens, Prism, Ray diagrams, Numerical problems related to this chapter, Laws of reflection, refraction, diseases related to eyes. I have briefly described as notes, some examples and illustrations, proper diagrams and so on.
This presentation is specially made for the students of grades 11 and 12 of High School. This is the presentation of chapter Atomic Structure with proper diagrams, figures, facts, mnemonics, and some repeated past questions. Here you will get a chance to know about Atomic theory, Daltons Law, particles and so on.
This is a presentation file that will provide you notes, proper diagrams, short tips, mnemonics about the alkali metals.. This course is of High School of grades 11 and 12. I think it will help every type of student. Similarly, you can find some repeated and important questions.
These are the suggestion to students who are starting their new academic semester or year. Every type of student can get their answers, daily routine, proper ways of studying, and so on.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
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Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
3. Pressure
• Force per unit area is called pressure. Its SI unit is
called Pascal.
• Pressure (P)= Force (F)/Area (A)
• Also Liquid Pressure (P)= hdg
• where, h=Height of liquid
column
• d=density of liquid
• g=Acceleration due to
gravity
4. Laws of Liquid Pressure
• Liquid cannot be compressed.
• Liquid pressure can be transmitted equally to all the
direct.
5. Pascal’s law
• When pressure is applied on a liquid enclosed in a
vessel, it is transmitted equally and perpendicularly
to all the direction.
8. • Consider a vessel filled with water and fitted with
pistons A,B,C and D as shown in the figure. If a
pressure is applied to piston A, other pistons B, C
and D move equally outward. This, proves that liquid
pressure is transmitted equally to all direction.
10. Hydraulic press
• Hydraulic press is machine based on pascal’s law
which multiply force and helps to press jute, cotton
etc in industries.
• Uses:
• 1. it is used to produce sugarcane juice from
sugarcane.
• 2. it is used make bales of cotton.
• 3. it is used to press jute, cotton etc.
12. Let, F1 = Force applied in small piston
A1= Area of cross- section of small piston
F2 = Force exerted in large piston
A2 = Area of cross – section of large piston
13. In small piston, P1 = F1/ A1 …………….i
In large piston, P2 =F2 / A2 …………….ii
From pascal’s law, P1 =P2
F1/A1 = F2 / A2
F2 = F1 / A1 × A2 …………….iii
Here, F2 is directly proportional to A2
so, greater the surface area of large piston, greater
will be the force multiplied.so hydraulic press is also
called force multiplier.
14. Hydraulic lift / Jack
• It is machine based on pascals law that multiplies
force and helps to lift heavy vehicles and heavy
loads.
• Uses:
• 1. it is used to lift heavy loads in industries, factories.
• 2. it is used to lift heavy vehicles in garage.
• 3. it is used to lift heavy loads in construction sides.
15.
16. Hydraulic Brake
• It is a machine based on pascals law that multiplies
force and helps to stop the running automobiles.
• Uses:
1. It is used to stop running vehicles, aeroplanes,
motorbike etc.
2. It is used to stop running automobile.
17.
18. Principle of Hydraulic
Machine
• It states, “A large force is developed on a larger
piston when a small effort is applied on the smaller
piston”.
19. Upthrust/ Buoyancy Force
• The resultant upward force exerted by a fluid or
liquid on an object immersed in the liquid is called
upthrust. It is denoted by “U”. Its SI unit is Newton
“N”.
• Upthrust(U)=vdg , where, v= volume of object
• d= density of liquid
• g=Acceleration due to gravity
•
21. • Let, w1 = weight in air
• w2 = weight in water
• Therefore, loss in weight = w1 – w2
• Loss of weight = upthrust = w1 – w2
• So, U = W1 – W2
22. Factors Affecting Upthrust
1. Volume of immersed body. ( U α V )
2. Density of liquid ( U α d )
3. Acceleration due to gravity ( U α g )
23. Archimedes’ principle
• It states that, “When a body is partially or wholly
immersed in a liquid, it experiences an upthrust
which is equal to the weight of liquid displaced by
it”.
• Upthrust= weight of displaced liquid.
25. • Let w1 = weight in air
• w2 = weight in liquid
• Upthrust ( U ) = w1 – w2
• Let, weight of beaker = w3
• weight of beaker + displaced liquid = w4
• Therefore, weight of displaced liquid = w4 – w3
26. • Experimentally it was found that
• W1 – w2 = w4 – w3
• Therefore, upthrust = weight if displaced liquid.
27. Law of Floatation
• When a body is floating in the liquid it displaces the
liquid equal to its weight.
• Therefore, weight of floating body = weight of
displaced liquid
28.
29. Applications of Archemides
Principle
• It is used for finding volume of irregular substance.
• It is used for finding weight of unknown substance.
• It is used in ship and hot air ballon.
30. Conditions of Floating and
Sinking
• When a body floats or sinks, two forces act upon it.
They are : a) weight of body ( downward )
b) upthrust ( upward )
There are 3 conditions of floating and sinking. They are:
1. When the weight of body is greater than the
upthrust, the body sinks. ( W > U ). It means if density
of object is more than liquid, the object sinks in the
liquid.
31. 2. When the weight of body is equal to the upthrust,
the body floats inside the liquid. ( W = U ). It means if
density of object is equal to liquid, the object floats
inside the liquid.
3. When the weight of body is less than the upthrust,
the body floats. ( W < U ). It means if density of object
is less than liquid, the object floats in the liquid.
32.
33. Application of Law of
Floatation
• It is used for floatation of submarine.
• It is used in floatation of iceberg, ship.
34. Density
Mass per unit volume of a substance is called density.
Its SI unit is kg/m3 .
Density ( d ) = mass( m )/ volume ( v )
Note:
1. Density of water is maximum at 4o C.
2. Density of water is 1000 kg/m3 . What do you mean
by it?
- It means 1m3 volume of water has mass 1000 kg.
35. Relative density ( R.d )
• The ratio of density of a substance to the density of
water at 4o C is called relative density.
• Relative density ( Rd ) = density of substance
• density of water at 4oC
• Note:
1. Relative density of silver is 10.5. what do you mean
by it?
- It means silver is 10.5 times heavier than water.
36. 2. Relative density of ice is 0.9. What do you mean by
it?
- It means ice is 0.9 times lighter than water.
37. Notes
• 1. an egg
sinks in fresh
water but
floats in the
concentrated
solution of
salt and
water. Why?
38. • It is because fresh water has less density than
concentrated salt solution. So, concentrated salt
solution gives more upthrust than fresh water, ( u α
d ).so, egg floats in concentrated salt solution.
39. • 2. an iron nail sinks in water but ship made by same
iron floats in water carrying heavy loads. Why?
40. • - It is because ship covers large space and it has
hollow space. So, entire density of ship lowers and
becomes less than water. So, ship can displace water
equal to its weight and floats.
41. • 3. weight of body decreases in water. why?
- It is because water gives maximum upthrust than air.
So, weight of body decreases inside water.
• 4. it becomes easy to swim in seawater. Why?
-It is because sea water contains maximum salt. So,
density of sea water is more. Sea water gives more
upthrust ( u α d ) and hence it becomes easy to swim in
sea water.
42. Atmospheric Pressure
• Pressure exerted by atmospheric air is called
atmospheric pressure. The pressure exerted by
atmospheric air at sea level is called standard
atmospheric pressure. It is about 760mmHg. It is also
1×105 pa.
• Since, p=hdg
• =0.76×13600×9.8
• = 1.01×105 pa
43. Experiment
• To demonstrate that atmospheric air exerts pressure.
• Let us consider a tin can and put a little water in the
tin can. Boil the water in the tin without closing its
mouth. Vapour is released outside from the can.
Close the mouth of tin can which lead tightly.
Remove the tin can from the fire and cool it by
pouring cold water over it. The tin can gets crushed.
It gets shrinking inward. This proves that,
atmospheric pressure exerts.
46. Measurement of Atmospheric
Pressure
• The atmospheric pressure can be measured with the
help of device called barometer. It was invented by
Italian physicist Evangelista Torricelli in 1643.
47. Mercury Barometer
• Construction: it consists of glass tube of 100cm long
inverted over a trough containing mercury ( Hg ). Pure
mercury is filled in it completely. Air bubbles if present,
are removed by closing the open end of the tube by a
thumb and inverting and shaking several times. Above
the mercury surface in the tube, a vacuum is created
which is called Torricellian vacuum.
• Working: when mercury barometer is taken to a certain
place the atmospheric pressure pushes the mercury in
the trough downward and the level of mercury increases.
The level of mercury increases or decreases according to
the height and atmospheric pressure.
50. Advantage of mercury
1. The mecury doesnot stick on the wall of glass tube.
2. Its density is high so the length of the glass tube in
barometer will be short.
3. It is shiny and read easily.
51. Disadvantage
• It is not portable size.
• It is to be kept always vertically to take the reading.
52. Use of Mercury Barometer
1. It is used to determined pressure in laboratories.
2. It is used in weather station to read atmospheric
pressure.
54. Syringe
• It is an instrument which is used by doctors or nurses
in hospitals to give injection to their patients. It
works on the principle of atmospheric pressure.
• Construction:
It consists of a piston , a barrel and a narrow method
tube in the form of a needle.
55. Working
When piston is pulled outside, volume inside
the barrel increases but pressure inside it decreases .
so, large atmospheric pressure pushes the medicine
into the syringe. This is called upstroke.
When piston is pushed inside , volume inside
the barrel decreases but pressure inside it increases. So
it helps to push the medicine into the patient’s body.
This is called down stroke.
57. Water Pump / Hand Pump
• It is an instrument which is used in rising water from
underground. It is based on the principle of
atmospheric pressure.
• CONSTRUCTION:
• It consists of a piston with a handle, a barrel, and a
metal pipe. There are two valves. One valve ( V1 )
lies in the piston which moves up and down.
Another valve ( V2 ) lies in the base of barrel which
goes well into the water reservoir.
58. Working
• When handle of hand pump is pushed down, the piston
moves up. So,volume of barrel in between two valves
increases and pressure in it decreases. So , valve v1 of
piston gets closed and valve v2 of base of barrel gets
opened. So, water from underground comes up in the
barrel due to large atmospheric pressure and water
comes out from nozzle. This is called upstroke.
• When handle of hand pump is pulled up, the piston
moves down. So,volume of barrel in between two valves
decreases and pressure in it increases. So , valve v1 of
piston gets opened and valve v2 of base of barrel gets
closed. So,water comes up to cylinder through valve v1.
This is called downstroke.
61. Air pump
• A bicycle pump or air pump is a type of positive
displacement pump specifically designed for inflating
bicycle tyres.
• CONSTRUCTION.
• it consists of three main parts . They are the piston,
cylinder and nozzle.
62. Working
• A bicycle pump functions via a hand operated piston.
During the upstroke,volume inside cylinder increases
and pressure in it decreases. So, this piston draws air
through a one way valve into the pump from the
outside. During the down stroke, volume inside the
cylinder decreases and pressure in it increases. So,
the piston then displaces the air from the pump into
the bicycle tyre.