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 NACO under the Ministry of Health,
Government of India, launched the
Prevention of Parent to ChildTransmission
(PPTCT) of HIV program in 2002
 In 2012, the multidrug regimen as
recommended by WHO has also been
accepted by the PPTCT program
 The services are provided through the ICTCs-
Integrated Counseling andTesting Centres
 Standalone ICTCs: located in the medical
colleges, district hospitals, taluk hospitals,
and community health centres
 Facility integrated ICTCs: located in the
primary health centre.The staff in PHC are
trained in counselling and testing for HIV
with kits provided. If a women tests positive,
she is referred to ICTCs.
 The aim of PPTCT programme is to offer
HIV testing to every pregnant women
(universal coverage) in the country, and
eliminate the transmission of HIV from
mother to child
 Antenatal care
 Intrapartum care
 Postnatal care
 Pretest and posttest counselling
>counseled regarding hygiene, nutrition, safe
sex and avoiding substance abuse, safe
delivery, birth planning and infant feeding
 Plasma viral load, CD4 counts, renal function
tests, and liver function tests done and
repeated every 3 months
 Offering termination of pregnancy to HIV-
positive women
 Screening for genital infections done early and
repeated at 28 weeks. Syphilis and hep B
screened on booking
 Detailed anomaly scan is a priority
 Hep B and pneumococcal vaccination is
recommended and safe
 Influenza vaccination also safe and can be
administered
>mumps, measles, rubella, varicella zoster
vaccines contraindicated
 Prophylaxis for Pneumocystis carinii
pneumonia is indicated when the CD4
count is <200/mm3- cotrimoxazole + folic
acid 5mg/day (CPT)
 Providing ART
 Psychosocial support
 Routine antenatal care
Pregnant and breastfeeding women with
HIV
Regardless of CD4 counts
or clinical stage (OR) CD4
count<500 (OR) clinical
stage 3 or 4
Lifelong
therapy with
TDF+3TC (or
FTC) + EFV
CD4 count >500
TDF+ 3TC (or FTC)
+ EFV
Stop ART after 1 week of
complete cessation of
breastfeeding
 Tenofovir (TDF) – 300 mg
 Lamivudine (3TC)- 300 mg
 Emtricitabine (FTC) – 200 mg
 Efavirenz (EFV) – 600 mg
 At birth, or when exposure is diagnosed
postpartum
 Infants (breastfeeding) – 6 weeks daily NVP
 Infants (replacement feeding)- NVP for 4-6
weeks or AZT twice daily
 Promotion of institutional deliveries of all HIV
infected women
 Caesarean section is the preferred mode of
delivery in HIV infected women
 Elective C-section is associated with reduced
rates of MTCT among women
>who have not received ARTs
>who have received AZT alone
>who have not achieved viral suppression
(>1000 copies/mL)
 In resource-limited regions
>vaginal delivery accepted
>amniotomy avoided unless delivery is
imminent
 Universal or standard precautions are
followed
 Care in handling of –
>blood (dried also),
>all other body substances, secretions
(including sweat), regardless of whether
they contain visible blood
>nonintact skin
>mucous membranes
Universal or standard precautions
Personal hygiene practices
>hand washing
PPE
>double gloving
>gowns
>protective eyewear
Aseptic technique
Safe disposal systems for
>sharps
>contaminated matter
Adequate sterilization of reusable equipment
Environmental controls
 Couselling regarding breastfeeding
>avoidance of breastfeeding is a definite way
to prevent transmission
>recommendation: exclusive breastfeeding
(exclusive replacement feeding) for 6
months inititated within an hour of delivery
 ART for mother and infant continued
 Family planning services
 EID- early infant diagnosis by HIV DNA PCR
 Sheila balakrishnan, 2nd edition
 Lakshmi seshadri, 1st edition
 K.Park, 23rd edition

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A Classical Text Review on BasavarajeeyamA Classical Text Review on Basavarajeeyam
A Classical Text Review on Basavarajeeyam
 

Pptct in pregnancy

  • 1.
  • 2.  NACO under the Ministry of Health, Government of India, launched the Prevention of Parent to ChildTransmission (PPTCT) of HIV program in 2002  In 2012, the multidrug regimen as recommended by WHO has also been accepted by the PPTCT program
  • 3.  The services are provided through the ICTCs- Integrated Counseling andTesting Centres  Standalone ICTCs: located in the medical colleges, district hospitals, taluk hospitals, and community health centres  Facility integrated ICTCs: located in the primary health centre.The staff in PHC are trained in counselling and testing for HIV with kits provided. If a women tests positive, she is referred to ICTCs.
  • 4.  The aim of PPTCT programme is to offer HIV testing to every pregnant women (universal coverage) in the country, and eliminate the transmission of HIV from mother to child
  • 5.  Antenatal care  Intrapartum care  Postnatal care
  • 6.  Pretest and posttest counselling >counseled regarding hygiene, nutrition, safe sex and avoiding substance abuse, safe delivery, birth planning and infant feeding  Plasma viral load, CD4 counts, renal function tests, and liver function tests done and repeated every 3 months  Offering termination of pregnancy to HIV- positive women
  • 7.  Screening for genital infections done early and repeated at 28 weeks. Syphilis and hep B screened on booking  Detailed anomaly scan is a priority  Hep B and pneumococcal vaccination is recommended and safe  Influenza vaccination also safe and can be administered >mumps, measles, rubella, varicella zoster vaccines contraindicated
  • 8.  Prophylaxis for Pneumocystis carinii pneumonia is indicated when the CD4 count is <200/mm3- cotrimoxazole + folic acid 5mg/day (CPT)  Providing ART  Psychosocial support  Routine antenatal care
  • 9. Pregnant and breastfeeding women with HIV Regardless of CD4 counts or clinical stage (OR) CD4 count<500 (OR) clinical stage 3 or 4 Lifelong therapy with TDF+3TC (or FTC) + EFV CD4 count >500 TDF+ 3TC (or FTC) + EFV Stop ART after 1 week of complete cessation of breastfeeding
  • 10.  Tenofovir (TDF) – 300 mg  Lamivudine (3TC)- 300 mg  Emtricitabine (FTC) – 200 mg  Efavirenz (EFV) – 600 mg  At birth, or when exposure is diagnosed postpartum  Infants (breastfeeding) – 6 weeks daily NVP  Infants (replacement feeding)- NVP for 4-6 weeks or AZT twice daily
  • 11.  Promotion of institutional deliveries of all HIV infected women  Caesarean section is the preferred mode of delivery in HIV infected women  Elective C-section is associated with reduced rates of MTCT among women >who have not received ARTs >who have received AZT alone >who have not achieved viral suppression (>1000 copies/mL)
  • 12.  In resource-limited regions >vaginal delivery accepted >amniotomy avoided unless delivery is imminent  Universal or standard precautions are followed
  • 13.  Care in handling of – >blood (dried also), >all other body substances, secretions (including sweat), regardless of whether they contain visible blood >nonintact skin >mucous membranes
  • 14. Universal or standard precautions Personal hygiene practices >hand washing PPE >double gloving >gowns >protective eyewear Aseptic technique Safe disposal systems for >sharps >contaminated matter Adequate sterilization of reusable equipment Environmental controls
  • 15.  Couselling regarding breastfeeding >avoidance of breastfeeding is a definite way to prevent transmission >recommendation: exclusive breastfeeding (exclusive replacement feeding) for 6 months inititated within an hour of delivery  ART for mother and infant continued  Family planning services  EID- early infant diagnosis by HIV DNA PCR
  • 16.  Sheila balakrishnan, 2nd edition  Lakshmi seshadri, 1st edition  K.Park, 23rd edition