The document discusses the buttonhole cannulation technique for vascular access in dialysis patients. It provides background on dialysis patients and costs in the US. The buttonhole technique creates fixed puncture sites in an arteriovenous fistula to reduce complications from cannulation. The literature review found the technique reduces pain and complications compared to the rope-ladder technique and has been used successfully in Europe for over 30 years. The document proposes evaluating the buttonhole technique for reducing cannulation pain, anxiety, and complications compared to the rope-ladder technique in outpatient dialysis clinics.