A general overview of the 2014 Outbreak of Cilantro Cyclosporiasis in Texas, United States. The poster below summarizes the investigation and secondary data analysis of the disease outbreak. It further highlights the important data and epidemiological information of the disease outbreak.
This poster was printed and presented in a Public Health Pandemics Seminar at the University of South Florida, College of Public Health, on January 29, 2015.
(c) Badru, M.A., & Perez, J. (2015)
Acute infectious diarrhea and gastroenteritis in childrenLucy Maya
Acute infectious diarrhea and gastroenteritis in children Acute infectious diarrhea and gastroenteritis in children Acute infectious diarrhea and gastroenteritis in children
Acute infectious diarrhea and gastroenteritis in childrenLucy Maya
Acute infectious diarrhea and gastroenteritis in children Acute infectious diarrhea and gastroenteritis in children Acute infectious diarrhea and gastroenteritis in children
Since its inception in 1989, Naperville Animal Hospital has remained committed to supporting the health of pets and finding loving homes for orphaned animals. In addition to providing routine care and around-the-clock emergency services for pets, Naperville Animal Hospital maintains affiliation with local professional organizations including the Chicago Veterinary Medical Association (CVMA).
One Health for the Real World: partnerships and pragmatismNaomi Marks
Presentation by Professor Sarah Cleaveland of the University of Glasgow at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, London 17-18 March 2016
Agricultural intensification and Nipah virus emergenceNaomi Marks
Presentation by Dr Jonathan Epstein, EcoHealth Alliance, at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, London 17-18 March 2016
About the national experience in the last pandemic flu in 2009. A descriptive analysis of the first national laboratory-confirmed cases of the diseases.
A critical social analysis of poverty and zoonotic disease riskNaomi Marks
Presentation by Professor Jo Sharp of the University of Glasgow at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, London 17-18 March 2016
Cyclospora is a serious food-borne illness that is becoming increasingly frequent in the US and can be contracted when you're traveling if you don't know how to prevent it. Learn how to stay safe from cyclospora.
Since its inception in 1989, Naperville Animal Hospital has remained committed to supporting the health of pets and finding loving homes for orphaned animals. In addition to providing routine care and around-the-clock emergency services for pets, Naperville Animal Hospital maintains affiliation with local professional organizations including the Chicago Veterinary Medical Association (CVMA).
One Health for the Real World: partnerships and pragmatismNaomi Marks
Presentation by Professor Sarah Cleaveland of the University of Glasgow at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, London 17-18 March 2016
Agricultural intensification and Nipah virus emergenceNaomi Marks
Presentation by Dr Jonathan Epstein, EcoHealth Alliance, at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, London 17-18 March 2016
About the national experience in the last pandemic flu in 2009. A descriptive analysis of the first national laboratory-confirmed cases of the diseases.
A critical social analysis of poverty and zoonotic disease riskNaomi Marks
Presentation by Professor Jo Sharp of the University of Glasgow at the One Health for the Real World: zoonoses, ecosystems and wellbeing symposium, London 17-18 March 2016
Cyclospora is a serious food-borne illness that is becoming increasingly frequent in the US and can be contracted when you're traveling if you don't know how to prevent it. Learn how to stay safe from cyclospora.
Investigation of Acute Gastroenteritis Epidemic (AGE) and its stepsMohsin Ansari
Steps of investigation of any epidemic are illustrated in the given slide especially for acute gastro-enteritis epidemic. Also the prevention of AGE is also given and at the end how to submit a report is also given.
Irritable Bowel Syndrome (IBS) and Fecal Microbiota Transplant. A new hope fo...Find Good Health
IBDs including irritable bowel syndrome (ibs) or ulcerative colitis (uc) are a set of diseases developing into an epidemic. The unusual and recent rise in these kind of diseases most notably on developed countries point to a recent and area specific etiology, not a better healthcare and diagnosis.
Recent researchs are pointing to a healthier immune system and intestinal flora in undeveloped countries' population and an imbalance in our gut flora caused by excessive use of antibiotics.
For more information about health and wellbeing visit our site at:
http://findgoodhealth.org/
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
1. University of South Florida College of Public Health
our practice is our passion.
2014 OUTBREAK OF CILANTRO CYCLOSPORIASIS IN TEXAS
Mariam A. Badru & Jennifer Perez
College of Public Health, University of South Florida
INTRODUCTION
Cyclosporiasis is an intestinal illness caused by a microscopic parasite called
Cyclospora Cayetanensis. People can become infected with Cyclospora by consuming
food or water that has been contaminated by the parasite. People living or traveling in
countries where cyclosporiasis is endemic may be at increased risk for the infection. It is
also very common in tropical or subtropical regions.3
Cyclosporiasis outbreak was spotted in the United States towards mid-2014. The number
of confirmed cases began to rise after May 1, 2014. However, as of August 26, 2014,
when the number of cases reduced to almost 0, the Center for Disease Control(CDC)
confirmed that:
There was a total of 133 cases of Cyclospora infection specifically among Texas
residents who did not travel outside the country within the two weeks prior to
becoming ill.
A total of four hospitalizations were reported in Texas during the outbreak
Texas state health officials reported that most cases of the illness occurred in June and
July 2014.
Many of these cases are linked back to humans consuming cilantro.2
Symptoms of Cyclosporiasis
METHODOLOGY
Epidemiological and trace back investigations were conducted at 4 different restaurants
in Texas, where multiple unrelated ill persons had reportedly eaten. All the ill persons
in these four clusters were also reported having eaten at least a food item containing
fresh cilantro about 2-14 days prior to becoming ill. Preliminary trace back
investigations carried out by the Food and Drugs Administration and the State of Texas
indicated that cilantro suppliers in Puebla, Mexico were a source of the cilantro that
was served at the four restaurants.3
Stool specimens were collected from each ill person infected with cyclosporiasis who
eat a cilantro-containing food at any of the four restaurants about 2-14 weeks prior to
the onset of their illnesses. Regular stool examinations are not efficient enough to
determine the cyclospora oocysts and as a result of this, scientists had to carry out
special lab testing specifically to detect the oocysts. 2
SYMPTOMS
Headaches Bloating
Fatigue Loss of Appetite Watery Diarrhea Nausea Vomiting
* Average Incubation Period: 2-14 Days.
* Disease can also remain asymptomatic for months.
* The most common symptom is watery diarrhea.1
RESULTS
Most of the confirmed cases of cilantro cyclosporiasis were significantly
associated with the consumption of cilantro-containing foods at restaurant
Figure 1: Confirmed Cases of Cyclosporiasis in Texas since May1, 2014.
The epi-curve shows the total laboratory confirmed cases of Cilantro
Cyclosporiasis (from May 1 – Aug 7) with no known history of international
travel outside the US 14 days before the onset of illness. The sample size, N
is 126. According to the graph, the two peaks occurred in mid-June and
early- July respectively. Overall, the epidemic was most prevalent between
June and July and then returned to the baseline level in August. 2
Figure 2: Populations affected by the cyclosporiasis infection.
Based on the information from the case control study:
• A total of 4 restaurants were identified as sources of the illness
• Each restaurant had 2-12 ill people with 100% of them reporting to have
consumed a cilantro-containing food at all 4 restaurants
CONCLUSIONS
Fresh cilantro from Puebla, Mexico was likely the source of cyclosporiasis illness among Texans in 2014. As a result of this, the Food and Drugs Administration(FDA) has
begun increased surveillance and sampling of food items at the US/Mexico Boarder to prevent future import of contaminated foods. The FDA is also continually working
with the Mexican authorities to investigate the farm practices being carried out in the production of cilantro. Preventive measures such as proper hygiene practices and safe
handling recommendations and inspection of restaurants are being promoted as well. There is also a treatment for it called Trimethoprim-sulfamethoxazole . However,
although the outbreak is likely to have ended, further investigations are still being carried out to make sure that there are no longer any confirmed cases that result from
asymptomatic or susceptible hosts. 2
REFERENCES
Cyclospora. (n.d.). Retrieved January 24, 2015, from http://www.dshs.state.tx.us/idcu/disease/cyclospora/
Cyclosporiasis Outbreak Investigations — United States, 2014. (2014, August 28). Retrieved January 24, 2015, from
http://www.cdc.gov/parasites/cyclosporiasis/outbreaks/2014/
U.S. Food and Drug Administration. (n.d.). Retrieved January 24, 2015, from http://www.fda.gov/Food/RecallsOutbreaksEmergencies/Outbreaks/ucm411990.htm
Cyclosporiasis Cases Population Affected % of Population
Total Confirmed Cases
(2014)
133 64% of Texas
Population
Confirmed Cases (After
May 1)
126 95% of Total Confirmed
Cases
Total Confirmed Deaths
(2014)
0 0%
Number reported eating
fresh cilantro 2-14 days
before illness
76 57%
Source: Center for Disease Control & Prevention 2014
Source of Data: Center for Disease Control & Prevention