Mr. X, a 55-year-old male, presented with a gradually enlarging painless swelling in his left parotid region over the past 5 years. Examination revealed a 7 cm x 6 cm firm, non-tender mass that was mobile and had a well-defined margin. Investigations including FNAC, USG, and MRI confirmed a diagnosis of pleomorphic adenoma. The patient underwent a superficial parotidectomy to remove the tumor. Histopathology of the resected specimen confirmed pleomorphic adenoma. The postoperative course was uneventful with intact facial nerve function and no complications.
Salivary gland tumours are a relatively rare and morphologically diverse group of lesions. So here are slides containing information about salivary gland tumours with images.
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5. HISTORY OF PRESENT ILLNESS
According to the statement of the patient, He was reasonably
well 5 years back. Then he developed a swelling in front of &
below the left ear for 5 years . It was initially small but
gradually increasing in size. The swelling was painless. He
has no facial paralysis.
6. HISTORY OF PAST ILLNESS
No history of radiation exposure.
PERSONAL HISTORY
Nothing significant.
FAMILY HISTORY
Nothing significant.
HISTORY OF MEDICAL ILLNESS:
No history of DM, HTN, Asthma.
TREATMENT HISTORY
Nothing significant.
7. GENERAL PHYSICAL EXAMINATION
Appearance : Normal
Body build : Average
Cooperation: : Cooperative
Nutrition : Average
Anaemia
Cyanosis
Jaundice
Dehydration Absent
Oedema
Clubbing
Koilonychia
Leukonychia
Heart : S1and S2 audible,
No added sound
Lungs : Clear
Pulse : 82/min, Regular.
BP :130/80mm of Hg
Temperature : 98.4°F
Resp . Rate : 18/min
9. LOCAL EXAMINATION
Inspection:
An oval swelling over the left side of the parotid region.
No scar mark, engorged vein & ulceration over the swelling was present.
Palpation:
Site : Left parotid region.
Size : 7 cm x 6 cm .
Shape : Oval.
Temperature : Normal.
Tenderness : Non tender.
Surface : Bosselated.
Consistency : Firm.
Margin : Well defined.
Fixity : Free from overlying skin & underlying structures.
ENT and Head-Neck EXAM
10. Relation with masseter : Free from masseter
Relation with TM joint : Free from TM joint
Relation with sternomastoid : Free from sternomastoid
Exam of oral cavity & pharynx : Normal
Examination of facial nerve : Intact on both side
Cervical Lymph node : Not palpable
13. Ear
Pinna
External auditory canal NAD
Tympanic membrane
mastoid
Nose
External nose
Anterior Rhinoscopy NAD
Posterior Rhinoscopy
Throat And Oral Cavity
Lip
Teeth
Gum
Tongue
Floor of the mouth NAD
Opening of parotid and
submandibular duct
Soft palate
Posterior pharyngeal wall
Tonsils and pillars
14. SALIENT FEATURE
Mr.X, 55 years of age, was admitted in hospital with the
complaint of a gradually increasing swelling on the left parotid
region for 5 years. It was 7 cm x 6 cm in diameter,non tender,
firm in consistency, surface was bosselated, margin was well
defined. It was free from overlying skin and underlying structures.
His facial nerve function was normal.
18. FNAC from left parotid swelling
Finding:
Histopathology reveals biphasic tumour composed of
epithelial element and stromal component arranged singly and
in sheet with large amount of myxoid material in the
background
Diagnosis: Pleomorphic Adenoma
19. USG parotid gland
Finding:
Overall size of left parotid gland is increased.There is
heterogenous hypoehoic area about 7 cm x 6 cm in diameter with
lobulated outline in superficial lobe of left parotid gland.No
calcification is noted.
•Diagnosis: Fairly large lobulated parotid mass lesion(Lt)
20. FINDING:
Fairly large (6.8 cm x 5.9 cm )
lobulated signal intensity
change area is noted in left side
of parotid gland. Anteriorly the
mass is extending up to
masseter muscle.
Right parotid gland is normal
in size. shape & signal intensity
without any focal lesion.
Impression:
Pleomorphic Adenoma(Lt)
MRI OF PAROTID GLAND
21. PRE-OP INVESTIGATIONS
Complete blood count
Hb % : 12.5 gm/dl
ESR : 08 mm in
1st hour
Total count : 9x109/L
Differential count
Neutrophil : 70%
Eosinophil : 2.2%
Basophil : 00%
Lymphocyte : 20%
Monocyte : 05%
Platelet count : 205x109/L
Bleeding time : 02/min
Coagulation time : 08/min
RBS : 4.9 mmol/L
Blood group : B +ve
Urine R/E : NAD
Serum urea : 27 mg/dl
Serum creatinine : 0.7 mg/dl
ECG : NAD
38. Histopathology report
Finding:
Sections reveals feature of
pleomorphic salivary adenoma. The
tumor is composed of epithelial
component and chondromyxoid
stroma .The epithelial cells are
disposed in sheets and ducts with foci
of squamous metaplasia
Histologic diagnosis: Pleomorphic
Adenoma
43. POST OPERATIVE MANAGEMENT
Drain was removed on 3rd post operative day.
Stiches were removed on 8th postoperative day.
Patient was discharged on 10th postoperative day.
44. Follow up
•Initially monthly for 3 months.
•Then 3 monthly for 1 year.
• 6 monthly for 5 yr.
• Then yearly for life long.
Includes:
• Thorough clinical
examination of parotid
region and neck
• If any suspicious lesion
then USG.
• Contrast MRI.
55. RULE OF 8O’s
80% of all salivary tumors occur in the parotid gland.
80% occurs in superficial lobe.
80% are benign tumor.
80% are pleomorphic adenoma.
56. Evaluation of Patients
1. History
Important points in the history:
- Parotid mass (duration, rate of the growth,
presence of pain)
- Facial paralysis
- Cervical lymphadenopathies
- Eyes and joints symptoms
- History of exposure to radiation
57. PRESENTATION
The tumors spherical or oval
Slow growing
Painless mass
Mobile
Foreign body sensation,dysphagia
Firm single nodular mass
58. Examination
• Site,
• Size,
• Shape,
• Temperature,
• Tenderness of the mass,
• Margin,surface
• Fixity-skin & underlying structures
• Relation with masseter
59. EXAM CONT…
Relation with TM joint & EAC
Relation with sternocleidomastoid
Examination of the oral cavity and
tonsillar fossa with special attention to
parotid duct.
Facial nerve functions
Cervical lymphadenopathies
60. INVESTIGATION
FNAC – important and diagnostic
USG –parotid gland
MRI with contrast
CT SCAN- in suspected bone involvement.
OPEN BIOPSY – contraindicated
Chance of injury to facial nerve.
Seedling & high chance of recurrence.
Parotid fistula formation.
61. Treatment
Surgery is the Treatment of choice
Minimum standard surgery is superficial parotidectomy.
Superficial parotidectomy- if only superficial lobe is
involved
Total conservative parotidectomy- if both lobes are
involved.
62. Landmark of facial nerve in parotid surgery
Tragal pointer
Tympanomastoid suture
Styloid process
Posterior belly of digastric
Retrograde identification
63. The post-operative complications:
Hematoma
Facial nerve paralysis – which could be:
Temporarily: 5 – 10% of the patients.
Permanent: less than 2% of the cases
Salivary fistula– it presents as an opening in the suture line
below the lobule of the ear
Frey’s syndrome .
Recurrence
Numbness of the ear due to injury of great auricular nerve.
Flap necrosis
64. RECURRENCE AFTER SURGERY
Inadequate excision of tumour
Spillage
Extracapsular extension
Retained pseudopods
65. CARCINOMA IN EX PLEOMORPHIC
ADENOMA
Long standing Pleomorphic adenoma-malignant
transformation
Recent increase in size
Pain , nodularity
Involvement of skin, ulceration
Involvement of masseter
Involvement of facial nerve
Neck lymph node
Restriction of jaw movements due to bone involvement
66. Malignant transformation may occur commonly after 20
yrs. This is due to radiation and genetic instability within the
tumor.
Different pattern of malignant change occur in
pleomorphic adenoma, of which carcinoma ex pleomorphic
adenoma is most commonly encountered.
Other two forms are Carcinosarcoma and metastasizing
pleomorphic adenoma.
67. PAROTID SURGERIES
0
2
4
6
8
10
12
14
16
2015 2016 2017
parotid surgery
superficial
parotidectomy
•No permanent facial
paralysis
•1 x recurrent case
developed mild temp
neuroprexia &
corrected.
(n=12)
(n=34)
68. Pleomorphic adenoma is most common benign tumor of
parotid gland. Minimum surgery is superficial parotidectomy .
Complete removal of tumor without spillage as well as
preservation of all branches of facial nerve is mandatory. As
facial expression and function is the prime concern of human
nature, identification & preservation of facial nerve, meticulous
surgery with bloodless field by skilled hand is needed to prevent
recurrence & morbidity.
CONCLUSION
Editor's Notes
The paired parotid glands are the largest of the major salivary glands and weigh, on average, 15–30 g.
Located in preauricular region and along the posterior surface of the mandible
Enters through posteromedial surface and exits through anteromedial surface of the parotid gland
Main trunk divides into the upper temporofacial and lower cervicofacial divisions approximately 1.3 cm from the stylomastoid foramen.
The upper temporofacial division forms the frontal, temporal, zygomatic, and buccal branches.
The lower cervicofacial division forms the marginal mandibular and cervical branches.