This document summarizes the capabilities of LightLab OCT technology for plaque characterization and precision imaging and therapy. LightLab OCT uses near-infrared light to provide ultra high-resolution imaging down to 12 micrometers. In addition to morphological imaging, it enables spectroscopic, polarization, Doppler, and elastography imaging. These advanced imaging modes allow for a better understanding of microanatomic plaque characteristics such as composition, structure, and orderliness. LightLab OCT technology has applications in selecting appropriate therapies, guiding targeted delivery, and developing new therapeutic approaches.