1ST, 2ND AND 3RD ORDER BENDS IN STANDARD EDGEWISE APPLIANCE SYSTEM /Fixed ort...Indian dental academy
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals
who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry,
Periodontics and General Dentistry.
1ST, 2ND AND 3RD ORDER BENDS IN STANDARD EDGEWISE APPLIANCE SYSTEM /Fixed ort...Indian dental academy
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals
who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry,
Periodontics and General Dentistry.
Finishing and retention in Begg appliance / fixed orthodontics coursesIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Soft tissue cephalometric analysis /certified fixed orthodontic courses by In...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Finishing and retention in Begg appliance / fixed orthodontics coursesIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Soft tissue cephalometric analysis /certified fixed orthodontic courses by In...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
2. Objectives
•Define Early Tx
•When you should refer a patient
•Who is (and is not) a good candidate for Early tx
•What common problems are addressed in Early tx
•What options are available to treat Early Patients
•How to determine success
3. Definitions of Early treatment
• Phase Therapy: early dental problems that left alone will create an
unhealthy environment for the growth and development of the teeth,
gums, bone and jaws
• Preventative/ Prophylactic: Prevent a problem from happening
• Interceptive Orthodontics: Intercept a developing problem
• Growth Modification: timing treatment to maximize and guide the
growth of the jaw bones that support the teeth
4. Treatment Phases
for Early/Interceptive Orthodontics
• Phase I (12-15 months)
• Maintenance Phase (12-24 mo)
• Phase II (12-15months)
Phase I active treatment Maintenance Phase II active treatment
12-15 months 12-24 months 12-18 months
The Big Question is …When and Who is a candidate for
Early Treatment
5. What is normal in a 7-year old
Class I Dental & Skeletal
occlusion
“Ugly-duckling” stage
(spacing and or minor
OB/OJ concerns
During transitional dentition,
perfect tooth alignment is
not to be expected and is
not cause for alarm.
7. What is NOT Normal
• Sagital relationships
such as
– Class II, dental and
skeletal
– Class III, dental,
skeletal and
functional shifts
8. Class II Skeletal Relationship
• 32% of malocclusions are Class II, but
they are 70% of what orthodontists treat
•The upper jaw is ahead of the lower jaw
(XS OJ or “buck teeth)
•In skeletal Class II, the jaws are
malaligned. Treatment can include
redirecting the eruption of teeth during jaw
growth Extraction Plan + FFA; or HPHG
•Excessive OJ leads to risk of trauma in
protrusive teeth.
•The upper jaw may be over developed,
but more often, the lower jaw is under-
developed.
•Untreated, skeletal malocclusions may
require orthognathic surgery to correct the
jaw position after growth is complete Growth Plan: Herbst/Forsus, HG
9. Class III Skeletal Relationship
Mandibular Prognathism usually dx in
adult (permanent dentition)
Midface deficiencies and maxillary
constriction is usually dx in the
• Characterized by anterior crossbite mixed dentition
•Approximately 3% of the malocclusions
•Can be caused by lack of growth in the upper jaw or excessive growth in the lower
jaw (seen later in development)
•Early treatment of maxillary sagital problem often includes a transverse component
•Early Class III treatment is best at age 7-10 as it requires significant compliance
with extra-oral headgear
10. Protraction Headgear
•Early Txt for Class III is primarily to affect maxillary growth.
•Requires RPE plus PHG and often FFA. Class III: Protraction/ reverse Pull
(often used with an RPE to aid in skeletal movement)
11. Functional Shifts
The position of the teeth affect the position of the jaw. When there is a
premature contact (see the canine) it can cause the jaw to shift so that
the teeth can contact. This can be habit forming and may result in
unwanted asymmetric growth.
12. Habits, Medical Problems
• Finger, thumb, Tongue thrust
• Speech discrepancies
• Mouth breathing due to airway constriction
(tonsils, adenoids)
• TMJ dysfunction, rheumatoid arthritis, and
growth hormone abnormalities may cause
orthodontic problems
13. Vertical Relationships-Open bites
• Dental vs Skeletal
• Habits such as finger/thumb sucking,
tongue thrust, or airway obstruction
• May result in chewing difficulty and
speech problem
• Tx may require ENT, habit therapy
and habit appliances
14. Vertical Relationships- Deep Bites
• Potential for abnormal tooth
wear and gingival
impingements
• May be skeletal cause:
vertical maxillary excess or
excessive curve of Spee
• This can be one of the most
damaging of malocclusions
15. Crossbite: Anterior
• Skeletal vs dental
• Can result from orthopedic problems or functional shifts
• All of these may damage the teeth and can cause long term gingival
problems
• These need to be corrected early to avoid damage to teeth and
gums
16. Crossbite: Posterior
• Often found in patients with a
narrow maxilla
• A posterior crossbite may also
cause a functional shift
• It may also appear as a
unilateral crossbite
• These are easily treated in the
growing child
17. Arch Length - crowding
• Causes
– Early loss of primary teeth
– Decay, genetics
– Tooth size problems
– Missing teeth
– Eruption problems
18. Arch Length-crowding
Premature loss of Primary Teeth
• Missing primary teeth, but adequate space
for secondary dentition= space maintainer
– Band and loop
– Lingual Arch
– Distal Shoe
– Nance
19. Arch Length-crowding
Irregular lower incisors
• Irregular Incisors, no arch-length/space discrepancy.
• Large Incisors + large primary molars +small premolars=
no space issues, but transient crowding & rotations of
the permanent incisors
• Up to 2mm of crowding may resolve spontaneously
• For 3-4mm of anterior crowding, IPR lower C’s and
place lingual arch **
20. Arch length-Crowding:
Delayed/blocked premolar development
• Aligned Incisors, no arch-length/space discrepancy.
• Erupting canine width+ erupting 1stPM width + large
primary 2nd molar width=transient crowding & rotations of
the erupting canines and premolars
• For posterior arch crowding, IPR lower E’s, hemi-section
or extract and place lingual arch
21. Arch Length-crowding
Localized space loss
• Localized space loss (3mm or less); Space Regaining
• Maxillary Regaining: tipping vs bodily movement
– Headgear or intra-oral appliance
– FFA
22. Arch Length-crowding
Localized space loss
• Localized space loss (3mm or less); Space Regaining
• Mandibular Regaining
– FFA or lip bumper
23. Arch Length-crowding
Midline discrepancy
• Premature loss of a primary tooth results
in a midline shift
• Tx with fingerspring or FFA
24. Arch Length-crowding
Severe
• Serial/Guided eruption (>10mm)
– No skeletal abnormality exists
(Class I)
– >10mm crowding
– Influence first premolars to
erupt prior to canines. For
mandible this means ext D’s
at ½ to 2/3 root formation on
4’s.
– Overbite might increase
during guidance but can be tx
after eruption of all permanent
teeth in a comprehensive
phase.
25. Arch Length - Spacing
Maxillary Midline Diastema
• Normal diastema = “ugly duckling stage”
• Larger diastema: >2mm =FFA
– Supernumeraries
– Missing permanent lateral incisors
– Tooth size discrepancy
– Tongue thrust
– Excessive tissue in the frenum
Tx indicated for 1) when the centrals inhibit
eruption of the laterals or canines, or 2)
esthetic issues (behavioral), 3) protrusion
and trauma risk
Studies prove that stability of the end result
is improved if a large diastema is
corrected before the full eruption of the
permanent dentition
28. Congenitally missing
permanent teeth
• Mandibular second premolars:
– Retention
– Ankylosis
•Delayed eruption
•Manage until it interferes with eruption or
drift of other teeth, then extracting and
placing space maintainer if necessary
•Monitor 1) tipping of molars over distal
marginal ridges of the ankylosed teeth 2)
super-eruption of opposing teeth
29. Ankylosed Teeth
Ankylosis: Fusion of the tooth to the bone
Primary Failure of eruption: Failure of permanent teeth to grow normally
Result: 1) Adjacent teeth continue to erupt & can tip forward, over the
primary teeth resulting in space loss; 2) the primary molars appear to sink
as the rest of the teeth and jaws continue to grow and develop. This will
cause a significant discrepancy in the alveolar bone height, an issue during
replacement when permanent teeth are missing
30. Early Treatment Rationale
• Phase I (12-15 months)
• Maintenance Phase (12-24 mo)
• Phase II (12-15months)
Phase I active treatment Maintenance Phase II active treatment
12-15 months 12-24 months 12-18 months
The Big Question is …When and Who is a candidate for
Early Treatment
32. Orthodontic Terminology
Sagital Dimension (AP)
• Dental (Angle Classification):
– Overjet(OJ): distance between the
upper & lower front teeth(mm)
– Molar position
– Canine position
• Skeletal: relation of maxilla and/or mandible
to the skull
• Goal: to “affect mandibular growth” or dental
compensation.
OJ Class II, Div 1 Class II, Div.2
33. Jaw Deformities
• Class II: Growth modification
Extraction Plan + FFA Growth Plan: Herbst/Forsus, HG
40. Disadvantages
• Time: most patients that require a phase I for
moderate to severe dental or jaw growth
modification will require a second phase.
• Money: increased cost to staging treatment into
2 phases is approximately $600
• OHI: poor motor skills may require more parental
involvement.
• Emergencies: higher risk of working on the
weekend