Dissolution and In Vitro In Vivo Correlation (IVIVC)Jaspreet Guraya
This presentation gives a bird's eye view on Dissolution in context with IVIVC. It discusses various levels of Correlations currently in practice. IVIVC are explained in light of biowaivers It also touches upon IVIVR, IVIVM etc.
CONCEPT OF LOADING AND MAINTAINANCE DOSE.pptxNamrataSawant19
Most drugs for chronic condition are prescribed in a dosage regimen is based on the administration of a fixed constant dose(D) at fixed regular dosing intervals(T) for long period of time.
The D & T recommended by the manufacturer is based on the effective therapeutic concentration of drug in the plasma needed to treat the chronic condition.
Primary purpose of using loading dose in therapeutic treatment is to attain steady-state concentration of the drug as quickly as possible, usually right from the start of the dosage regimen for the treatment.
Dissolution and In Vitro In Vivo Correlation (IVIVC)Jaspreet Guraya
This presentation gives a bird's eye view on Dissolution in context with IVIVC. It discusses various levels of Correlations currently in practice. IVIVC are explained in light of biowaivers It also touches upon IVIVR, IVIVM etc.
CONCEPT OF LOADING AND MAINTAINANCE DOSE.pptxNamrataSawant19
Most drugs for chronic condition are prescribed in a dosage regimen is based on the administration of a fixed constant dose(D) at fixed regular dosing intervals(T) for long period of time.
The D & T recommended by the manufacturer is based on the effective therapeutic concentration of drug in the plasma needed to treat the chronic condition.
Primary purpose of using loading dose in therapeutic treatment is to attain steady-state concentration of the drug as quickly as possible, usually right from the start of the dosage regimen for the treatment.
An emulsion is a mixture of two or more liquids that are normally immiscible. Emulsions are part of a more general class of two-phase systems of matter called colloids.
Non compartmental pharmacokinetics & physiologic pharmacokinetic models by aktDr Ajay Kumar Tiwari
Non Compartmental Analysis
-Assumptions to be made
-Statistical Moment Theory
-Mean Residence Time
-Mean Transit Time (MTT), Mean Absorption Time (MAT), and Mean Dissolution Time (MDT)
-Other Pharmacokinetic Parameters
-Advantages and Disadvantages of Noncompartmental Versus Compartmental Population Analyses
Physiologic Pharmacokinetic Models
-Physiologically based pharmacokinetic (PBPK) modeling
-Assumption to be made
-advantages & disadvantage
In this slide contains introduction, copmpression, consolidation, compaction, heckel plots and equation, interpretation and application.
Presented by: NARAYAN SINGH UDIT (Department of pharmaceutics).
RIPER, anantapur
An emulsion is a mixture of two or more liquids that are normally immiscible. Emulsions are part of a more general class of two-phase systems of matter called colloids.
Non compartmental pharmacokinetics & physiologic pharmacokinetic models by aktDr Ajay Kumar Tiwari
Non Compartmental Analysis
-Assumptions to be made
-Statistical Moment Theory
-Mean Residence Time
-Mean Transit Time (MTT), Mean Absorption Time (MAT), and Mean Dissolution Time (MDT)
-Other Pharmacokinetic Parameters
-Advantages and Disadvantages of Noncompartmental Versus Compartmental Population Analyses
Physiologic Pharmacokinetic Models
-Physiologically based pharmacokinetic (PBPK) modeling
-Assumption to be made
-advantages & disadvantage
In this slide contains introduction, copmpression, consolidation, compaction, heckel plots and equation, interpretation and application.
Presented by: NARAYAN SINGH UDIT (Department of pharmaceutics).
RIPER, anantapur
Nonlinear Pharmacokinetics
-Tests to detect nonlinearity in pharmacokinetics
-CAUSES OF NONLINEARITY
-MICHAELIS MENTEN EQUATION
-Estimation of Km and V max
-Km and V max from Steady State Concentration
Multiple Dosage Regimens
1. Define the index for measuring drug accumulation.
2. Define drug accumulation and drug accumulation t1/2
3. Explain the principle of superposition and its assumptions in multiple dose regimens.
4. Describe Repetitive Intravenous injections One Compartment Open Model
5. Describe Repetitive Extravascular dosing One Compartment Open model
6. Describe Multiple Dose Regimen Two Compartment Open Model
MULTICOMPARTMENT MODELS
TWO COMPARTMENT OPEN MODEL
-Intravenous Bolus Administration
-Intravenous Infusion
-Extravascular administration
-method of residuals
-Urinary excretion data
-Loo Riegelman method
One-compartment open model
1.One compartment open model intravenous bolus administration.
2.One compartment open model continuous intravenous infusion .
3.One compartment open model extravascular zero order absorption .
4.One compartment open model extravascular first order absorption
1.Definition and introduction to Pharmacokinetics.
2.Basic considerations in Pharmacokinetics.
3.Pharmacokinetic models.
4.Compartment models.
5.Pharmacokinetics parameters
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
Introduction to Change Control.
Definition of Change Control.
Function of Change Control.
Area of Change.
Written Procedures and Documentation.
Qms NATIONAL ACCREDITATION BOARD FOR TESTING AND CALIBRATION LABORATORIES (...Dr Ajay Kumar Tiwari
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
1. Introduction to NABL
2. NABL and ISO Principles
3. Need of NABL
4. Recognition of NABL in International Level
5. Scope of NABL
6. Advantages of NABL
quality management systems: Total quality management & Quality by designDr Ajay Kumar Tiwari
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
Total quality management
Quality by design
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
Introduction to OOS
Identification of OOS: Reports of Laboratory Investigation
Responsibility of Analyst and Supervisor
Identification of OOS:
Reports of Full Scale Investigation
Review of Manufacturing, Production and Sampling
Review of Lab Investigation Result
Supplementary Laboratory Testing Procedure
Analysis of Investigated Results
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
Si x sigma concepts.
Aim of 6 sigma concepts.
Process of 6 sigma concepts.
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
ISO Quality Standards
1. Quality Management System (QMS)
2. ISO Quality Standards
3. ISO 9000
4. ISO 9000 Series
5. Requirements of ISO 9000 Series
6. Advantages of ISO Certification
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
ISO Quality Standards
1. Introduction to ISO 14000
2. Principle of ISO 14000
3. Features of ISO 14000
4. Advantages of ISO 14000
5. ISO 14000 Series
6. Process of ISO 14001 Certification
7. Environmental Management System (EMS)
8. Features of EMS
Quality management systems: Good Laboratory Practice (QMS GLP)Dr Ajay Kumar Tiwari
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
1. Introduction to GLP
2. Definition of GLP
3. Fundamentals of GLP
4. GLP Principles
5. Aim of GLP
Fundamental knowledge on pharmaceutical
product development and translation from laboratory to market.
Quality management systems: Quality management & Certifications.
Quality concepts in pharmaceutical industry
ICH guidelines and Total quality management
Quality by design and six sigma concepts
ISO standards and series
Good laboratory practice
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxEduSkills OECD
Andreas Schleicher presents at the OECD webinar ‘Digital devices in schools: detrimental distraction or secret to success?’ on 27 May 2024. The presentation was based on findings from PISA 2022 results and the webinar helped launch the PISA in Focus ‘Managing screen time: How to protect and equip students against distraction’ https://www.oecd-ilibrary.org/education/managing-screen-time_7c225af4-en and the OECD Education Policy Perspective ‘Students, digital devices and success’ can be found here - https://oe.cd/il/5yV
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
We all have good and bad thoughts from time to time and situation to situation. We are bombarded daily with spiraling thoughts(both negative and positive) creating all-consuming feel , making us difficult to manage with associated suffering. Good thoughts are like our Mob Signal (Positive thought) amidst noise(negative thought) in the atmosphere. Negative thoughts like noise outweigh positive thoughts. These thoughts often create unwanted confusion, trouble, stress and frustration in our mind as well as chaos in our physical world. Negative thoughts are also known as “distorted thinking”.
How to Create Map Views in the Odoo 17 ERPCeline George
The map views are useful for providing a geographical representation of data. They allow users to visualize and analyze the data in a more intuitive manner.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.