This document discusses factors to consider when selecting materials for pharmaceutical plant construction. It begins by stating that a variety of equipment and materials are used to process and package pharmaceutical products. The key factors that affect material selection are then outlined as chemical factors, physical factors, and economic factors. Chemical factors concern contamination of the product and corrosion of materials. Physical factors relate to strength, mass, thermal properties, ease of fabrication, cleaning and sterilization. Economic factors consider the overall cost. Common materials used in plant construction are then classified as ferrous metals, non-ferrous metals, organic non-metals, and inorganic non-metals.

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SESSIONAL EXAM PATTERN

3. UNIT -5
MATERIAL OF PLANT CONSTRUCTION,
CORROSION AND ITS PREVENTION
• INTRODUCTION
• For manufacturing of
Pharmaceutical bulk drugs number
of equipments are used
• The equipment are generally used
for processing and Packaging of
product.
• A wide variety of material are used
for manufacturing of this
equipment.

5. INTRODUCTION
• Therefore design of equipment, material
selection and fabrication technique needed to be
considered carefully.
• These factor affects the success or failure of new
chemical plant.
• The proper choice of material is very important
• The material used for the construction of plant is
classified as metal ferrous and non ferrous and
non metal organic and inorganic.
• Therefore there are lots factors which affects
material selected for plant construction

6. FACTORS AFFECTING DURING MATERIALS
SELECTED FOR PHARMACEUTICAL PLANT
CONSTRUCTION
• The selection of material for construction of equipment
depends on following properties :
CHEMICAL FACTORS PHYSICAL FACTORS ECONOMIC FACTORS
Contamination of Product Strength
Corrosion of material construction Mass
Wear properties
Thermal conductivity
Thermal expansion
Ease of fabrication
Cleaning
Sterilization
Transparency

7. CHEMICAL FACTORS
•Each time a chemical is placed in a container or equipment the chemical is
exposed to construction material of the container or equipment.
•Therefore the construction material can contaminate the product or the
product can destroy the construction.

8. PHYSICAL FACTORS:

9. PHYSICAL FACTORS:

10. ECONOMIC FACTORS

11. CLASSIFICATION OF MATERIAL FOR
PLANT CONSTRUCTION

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