This document discusses perineal hernia in dogs. It begins by defining hernia and classifying hernias based on location, functional alterations, and contents. It then describes perineal hernia specifically, noting that it is abnormal protrusion of pelvic or abdominal viscera through the pelvic diaphragm. Causes include straining, congenital weakness, trauma, and breed disposition. Diagnosis involves palpating a perineal swelling and signs like constipation. Treatment is usually surgical herniorrhaphy to repair the hernial ring. The document concludes by presenting a case study of surgical repair of a left perineal hernia in a dog.
Hernias (as an inguinal hernia, umbilical hernia, or spigelian hernia) in which an anatomical part (as a section of the intestine) protrudes through an opening, tear, or weakness in the abdominal wall musculature.
Various types of hernia are dealt by a general or laparoscopic surgeon
For details plz visit - https://drnitinjha.com/
https://drnitinjha.com/inguinal-hernia-surgery-noida/
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
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Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
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comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
4. Hernia
• Abnormal protrusion of contents of a body
cavity through normal or abnormal
opening
• Constituents of hernia –
Hernial ring
Hernial sac
Hernial contents – Intestine, Omentum,
Urinary Bladder, etc.
5. Classification
Based on Location :
i) External hernia – Ventral H, Inguinal H,
Umbl. H, Perineal H
ii) Internal Hernia – Diaph. H
Based on functional alterations:
i) Reducible
ii) Irreducible – incarcerated H
strangulated H
6. Classification
III. Based on hernial contents
i) Enterocoele – intestines
ii) Epliplocoele – Omentum
iii) Reticulocoele – reticulum
iv) Vesiculocoele – urinary bladder
IV. Based on cause
i) Congenital – anatomical variations
ii) Acquired – trauma
8. Treatment:
• Reduction of contents and application of
bandages for 2-3 weeks
• Local infiltration of irritants
• Herniorrhaphy – suturing of hernial ring
• Hernioplasty – covering the gap
with mesh and suturing it
• Kelotomy – enlarging the hernial ring
9. Perineal hernia
• It is abnormal protrusion/ displacement of pelvic or
abdominal viscera through the weakened/ruptured
pelvic diaphragm into the region around the anus called
the perineum.
• It occurs when the perineal muscles separate, allowing
the rectal, pelvic or abdominal contents to displace.
• It is common in dog and un common in ruminants but
has been recorded in cattle and buffaloes
• This condition occurs secondary to a weakening of the
muscles
10. Pelvic diaphragm is composed of:
• Coccygeus muscle
• Levator ani muscle
• External anal sphincter muscles.
12. Etiology
• Cause of pelvic diaphragm weakening is poorly
understood but is believed to be associated with male
hormones
• Straining
• Congenital or acquired muscle weakness-tenesmus
• Atrophy
• Trauma
• Breed disposition – welsh corgies, boxers, boston
terriers,coolies
• Sex
• Tail docking
• Prostatic enlargement
13. Classifications of Perineal Hernia
• Based on Location
1. Unilateral
2. Bilateral
• Based on Position
1. Dorsal
2. Ventral
3. Sciatic or Caudal
Hernias
14. Hernial Contents and Hernial Sac
• Contents are contained in perineal fascia as perineal
peritonium is usaully intact so it forms the true sac
• Contents may include
1. Pelvic or retroperitneal fat
2. Peritonial fluid
3. A deviation, dilation or sacculation of the rectum
4. A rectal diverticulum
5. Prostrate gland
6. Urinary bladder
7. Small intestines
15. Diagnosis
• History
– Affected animals usually are presented for treatment because of
difficulty in defecation or urination
– Some owners notice swelling lateral to the anus
• Clinical signs
– Perineal swelling
– Constipation
– Dyschezia
– Tenesmus
– Rectal prolapse
– Stranguria
– Anuria
– Vomition
– Fecal incontenance
– Digital palpation of hernial ring
17. Biochemical analysis
• If urinary bladder is involved( stranguria,anurea)
1. Raised serum urea
2. Raised serum creatinine
3. Raised phosphate concentrations
4. Raised serum potassium concentrations- usually after
24 hrs. of obstruction.
18. Diagnostic Imaging
• Usually not required
• Ultrasonography can be done to ascertain the
presence of absence of small intestine, prostrate, U
bladder
• Positive contrast cytogram – U.B.
19. Surgico-medicinal management
• The goal of treatment is to relieve and prevent
constipation, dysuria and organ strangulation
1. Conservative management
• Causative factors should be corrected
• Normal defection sometimes can be maintained using
laxative , stool softeners , dietary changes , enema.
• High fibre diet
• Occasional enema or manual evacuation of faeces
20. Cont…..
2. Surgical management
• Herniorrhaphy should always be recommended.
• Castration is recommended during herniorrhaphy
because it has been reported to reduce recurrence
• Non castrated dogs have a recurrence rate 2.7
times greater than castrated dogs.
25. Prognosis after surgery
• Favourable- 15% reoccurance
• Antibiotics, stool softeners, high fibre diet shall be
given
• Elizabethan collar
• Dogs with bilateral hernia shall have one side
repaired at a time
26. CASE NO:- 1318
A Soft puffy swelling palpable of the left side in the perineal
region just below the base of tail
28. • History;
– Constipation
– Swelling on lateral side of anus from last 2 months
– Loss of appetite
• Clinical signs
– Perineal swelling
– Constipation
– Dyschezia
– Tenesmus
29. Diagnosis
Palpation of the affected site revealed
hernial ring
Based on history and clinical signs the case
was diagnosed as perineal hernia and
surgical intervention was advised
30. Premedication & Anaesthesia
• Atropine sulphate @ 0.04mg /kg b wt. i/m
• Diazepam @ 0.5mg/kg b wt. i/v
• Xylazine @ 2 mg/kg b wt. i/m
• Ketamine Hydrochloride @ 10 mg./kg b wt. i/v
41. Post operative care
• Ceftriaxone @ 20 mg/kg b wt. i/m for 3 days
• Melonex @ 0.5 mg/kg b wt. i/m for 3 days
• CPM @ 0.25mg/kg b wt i/m
for 3 days
• Liquid diet for 5 days