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Pelvic inflammatory disease (PID)
how to diagnose ?
presented by final year
medical student
Ali Kareem
Definition
• Pelvic Inflammatory Disease (PID) comprises a
spectrum of inflammatory disorders of the upper
female genital tract, including any combination of
endometritis, salpingitis, oophoritis, pelvic peritonitis
and subsequently leading to tubo-ovarian and pelvic
abscess.
• Sexually transmitted organisms, especially N.
gonorrhoea and C. trachomatis, are implicated in
many cases.
• Others , : bacterial vaginosis may be identified.
Epidemiology
• PID is commonly associated with Sexually
Transmitted Diseases (STDs).
• Occur in 2% of sexually active females.
• About 85% are spontaneous infection in sexually
active females of reproductive age.
• Remaining 15% follow procedures, which favors the
organism to ascend up.
Etiology & Pathophysiology
❖Ascending: common, from the LGT.
⮚1. Through sperm, TV, along surfaces traveling
from the cervix to the endometrium, through the
tubes into the peritoneal cavity.
⮚2. Through the lymphatic systems: infection of the
parametrium from IUCD.
❖Lateral: Rare, from infected appendix
❖Through hematogenous routes
• Iatrogenic procedures: favor organism to
ascend
1. Endometrial biopsy
2. Uterine curettage
3. Insertion of IUD
4. Hysterosalpingography.
Mode of transmission
• Ascend of gonococcal & chlamydial
organisms by surface extension from the
lower genital tract through the cervical canal
by way of the endometrium to the fallopian
tubes
• Facilitated by the sexually transmitted
vectors such as sperms & trichomonads
• Or Reflux of menstrual blood along with
gonococci into the fallopian tubes may be
the other possibility.
• Through uterine lymphatic & blood vessels
across parametrium. Like
⮚Mycoplasma hominis
⮚Secondary organisms
risk factors
❖I. Factors related to sexual behavior:-
⮚young age
⮚multiple partners
⮚recent new partner (within previous 3 months)
⮚past history of (STIs) in the patient or their partner
❖II. Instrumentation of the uterus / interruption of
the cervical barrier
⮚termination of pregnancy
⮚insertion of IUCD for the 1st 3 wks of insertion.
⮚HSG
⮚IVF &IUI .
Acute PID
• Signs and symptoms vary in women who are
symptomatic.
• Symptoms develop during or following menstruation.
• The clinical criteria :
1. Pelvic tenderness and cervical excitation
2. Uterine tenderness
3. Tender adnexal or palpable ovarian mass.
• Additional criteria
ξ Mucopurulent vaginal discharge
ξ Elevated C- reactive protein or ESR
ξ Tempreature >> 38*C
Acute PID presentation & Hx
History
✔ location, intensity, radiation, timing, duration, and
exacerbating and mitigating factors of the pelvic pain:
Bilateral lower abdominal & pelvic dull aching pain is
characteristic of acute PID
✔ H/O Fever (Oral temperature > 38.3˚C/101F)
✔ H/O Abnormal vaginal discharge
✔ H/O symptoms suggestive of dysuria
✔ Previous H/O abdominal or gynecological surgeries
✔ H/O previous gynecological problem
✔ H/O IUD insertion (6 times higher risk within 20 days)
✔ Social history: Should include patient’s sexual and
✔ STDs history & partner’s history in terms of STDs
❖Fitz Hugh & Curtis Syndrome
• Consists of rt. upper quadrant pain resulting
from ascending pelvic infection and
inflammation of the liver capsule or diaphragm
{adhesion}.
❖Physical examination
• Bilateral abdominal tenderness
• Adnexal mass & adnexal tenderness
• Cervical motion tenderness
• Uterine tenderness
• Vaginal mucopurulent discharge
Dx criteria
• US ⮚ tubo-ovarian abscess
• Laparoscopy: visually confirming salpingitis
• Screening for STI (specially those who +
gonorrhea, chlamydia )
– Microscope and or culture for T. vaginalis
– HIV AB test
– Syphilis serology
– Urine culture & analysis to exclude UTI.
Most common DD of acute PID
1. Appendicitis.
2. Ectopic pregnancy.
3. Endometritis.
4. Ovarian cyst.
5. Ovarian torsion.
PID chronic complication
• This diagnosis is given to women who describe a history of acute PID and
who have pelvic pain.
• Hydrosalpinx might qualify as criterion for it.
• Histologically diagnosed >> pyogenic infection
❖ complication
⮚ Dyspareunia
⮚ Infertility : due to tubal factor
✔ 12 % after single episode
✔ 25 % after two episodes
✔ 50 % after three episodes
⮚ Increased risk of ectopic pregnancy
✔ 6-10 % increase in risk following H/O PID
⮚ Formation of adhesion or hydrosalpinx or pyosalpinx & tubo -ovarian
abscess
⮚ Chronic pelvic inflammation
✔ Due to recurrent or associated pyogenic infection/ T.B.
⮚ Chronic pelvic pain and ill health
❑Symptoms
• Chronic pelvic pain
• Dyspareunia
• dysmenorrhea
• Lower abdominal pain
• Menorrhagia
• Vaginal discharge
• Infertility
❑Signs
o Tenderness on one or both iliac fossa
o An irregular tender pelvic mass
o PR Involvement of parametrium & uterosacral
ligament

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Pelvic inflammatory disease (PID)

  • 1. Pelvic inflammatory disease (PID) how to diagnose ? presented by final year medical student Ali Kareem
  • 2. Definition • Pelvic Inflammatory Disease (PID) comprises a spectrum of inflammatory disorders of the upper female genital tract, including any combination of endometritis, salpingitis, oophoritis, pelvic peritonitis and subsequently leading to tubo-ovarian and pelvic abscess. • Sexually transmitted organisms, especially N. gonorrhoea and C. trachomatis, are implicated in many cases. • Others , : bacterial vaginosis may be identified.
  • 3. Epidemiology • PID is commonly associated with Sexually Transmitted Diseases (STDs). • Occur in 2% of sexually active females. • About 85% are spontaneous infection in sexually active females of reproductive age. • Remaining 15% follow procedures, which favors the organism to ascend up.
  • 4. Etiology & Pathophysiology ❖Ascending: common, from the LGT. ⮚1. Through sperm, TV, along surfaces traveling from the cervix to the endometrium, through the tubes into the peritoneal cavity. ⮚2. Through the lymphatic systems: infection of the parametrium from IUCD. ❖Lateral: Rare, from infected appendix ❖Through hematogenous routes
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  • 6. • Iatrogenic procedures: favor organism to ascend 1. Endometrial biopsy 2. Uterine curettage 3. Insertion of IUD 4. Hysterosalpingography.
  • 7. Mode of transmission • Ascend of gonococcal & chlamydial organisms by surface extension from the lower genital tract through the cervical canal by way of the endometrium to the fallopian tubes • Facilitated by the sexually transmitted vectors such as sperms & trichomonads • Or Reflux of menstrual blood along with gonococci into the fallopian tubes may be the other possibility.
  • 8. • Through uterine lymphatic & blood vessels across parametrium. Like ⮚Mycoplasma hominis ⮚Secondary organisms
  • 9. risk factors ❖I. Factors related to sexual behavior:- ⮚young age ⮚multiple partners ⮚recent new partner (within previous 3 months) ⮚past history of (STIs) in the patient or their partner ❖II. Instrumentation of the uterus / interruption of the cervical barrier ⮚termination of pregnancy ⮚insertion of IUCD for the 1st 3 wks of insertion. ⮚HSG ⮚IVF &IUI .
  • 10. Acute PID • Signs and symptoms vary in women who are symptomatic. • Symptoms develop during or following menstruation. • The clinical criteria : 1. Pelvic tenderness and cervical excitation 2. Uterine tenderness 3. Tender adnexal or palpable ovarian mass. • Additional criteria ξ Mucopurulent vaginal discharge ξ Elevated C- reactive protein or ESR ξ Tempreature >> 38*C
  • 11. Acute PID presentation & Hx History ✔ location, intensity, radiation, timing, duration, and exacerbating and mitigating factors of the pelvic pain: Bilateral lower abdominal & pelvic dull aching pain is characteristic of acute PID ✔ H/O Fever (Oral temperature > 38.3˚C/101F) ✔ H/O Abnormal vaginal discharge ✔ H/O symptoms suggestive of dysuria ✔ Previous H/O abdominal or gynecological surgeries ✔ H/O previous gynecological problem ✔ H/O IUD insertion (6 times higher risk within 20 days) ✔ Social history: Should include patient’s sexual and ✔ STDs history & partner’s history in terms of STDs
  • 12. ❖Fitz Hugh & Curtis Syndrome • Consists of rt. upper quadrant pain resulting from ascending pelvic infection and inflammation of the liver capsule or diaphragm {adhesion}. ❖Physical examination • Bilateral abdominal tenderness • Adnexal mass & adnexal tenderness • Cervical motion tenderness • Uterine tenderness • Vaginal mucopurulent discharge
  • 13. Dx criteria • US ⮚ tubo-ovarian abscess • Laparoscopy: visually confirming salpingitis • Screening for STI (specially those who + gonorrhea, chlamydia ) – Microscope and or culture for T. vaginalis – HIV AB test – Syphilis serology – Urine culture & analysis to exclude UTI.
  • 14. Most common DD of acute PID 1. Appendicitis. 2. Ectopic pregnancy. 3. Endometritis. 4. Ovarian cyst. 5. Ovarian torsion.
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  • 17. PID chronic complication • This diagnosis is given to women who describe a history of acute PID and who have pelvic pain. • Hydrosalpinx might qualify as criterion for it. • Histologically diagnosed >> pyogenic infection ❖ complication ⮚ Dyspareunia ⮚ Infertility : due to tubal factor ✔ 12 % after single episode ✔ 25 % after two episodes ✔ 50 % after three episodes ⮚ Increased risk of ectopic pregnancy ✔ 6-10 % increase in risk following H/O PID ⮚ Formation of adhesion or hydrosalpinx or pyosalpinx & tubo -ovarian abscess ⮚ Chronic pelvic inflammation ✔ Due to recurrent or associated pyogenic infection/ T.B. ⮚ Chronic pelvic pain and ill health
  • 18. ❑Symptoms • Chronic pelvic pain • Dyspareunia • dysmenorrhea • Lower abdominal pain • Menorrhagia • Vaginal discharge • Infertility ❑Signs o Tenderness on one or both iliac fossa o An irregular tender pelvic mass o PR Involvement of parametrium & uterosacral ligament