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Pediatric Airway
Management:
Leave the
Cowboy Hat
Behind
Maria J. Mandt, MD
Associate Professor of Pediatrics
Medical Director of EMS
Medical Director Flight For Life, Children’s
Hospital Colorado Team
I have no relevant financial
disclosures
Quality is not an act. It is a habit.
- Aristotle
• Discuss the clinically relevant differences
between the pediatric and adult airways
• Identify predictors of a difficult pediatric
airway
• Formulate a plan in the event of an
unanticipated difficult pediatric
intubation
Time to Talk Objectives, Cowboy
Photo credit: www.theredlist.com
Low incidence, high risk. . .
CCT intubation statistics:
• 1.3% of trips involve peds/neo intubation
• Difficult airway predictors present in 77%
• Neonatal 1st-pass success rate: 59.3%
• Neonatal 1st-pass success without hypoxia or hypotension:
30.8%
• Pediatric 1st-pass success rate: 81.7%
• Pediatric 1st-pass success rate without hypoxia or
hypotension: 60.7%
What should we take away from these numbers?
Burns BJ et al. Ann Emerg Med 2017; Reichert, RJ
et al. Prehosp Emerg Care 2018
Scared now? You Need a Plan
Photo credit:
https://www.youtube.com/watch?v=DwzCrhth090
If you climb in the saddle, be ready
for a ride. . . .
Learn the 7 Ps of
Preparation:
Prior Proper Planning
Prevents Piss Poor
Performance
Photo credit: www.coburgbanks.co.uk
Oh, baby. . . Let
me count the
ways
Critical differences
between the big and
the small
Prominent occiput
Management:
• Shoulder roll for all < 8
years of age
Implication:
• Neck flexion causes UAO
• O/P/L axes not aligned,
making laryngoscopy
difficult
Photo credit: JEMS.com,
Cephalad Larynx
Implication:
• Shorter distance between
tongue and epiglottis
creates acute angle
• Larynx seems more
anterior
Management:
• Optimal positioning
• Gentle cricoid
Photo credit: www.youtube.com/watch?v=EIty86wXmB8
Epiglottis angled over vocal cords
Implication:
More difficult to lift epiglottis and
visualize VC
ETT can get caught on anterior
commissure of VC
Management:
• Gentle cricoid
• Straight blade in
children under 3
Pediatric
Adult
Significant soft tissue and large
tongue
Management:
• OPA
• Lateral approach
to laryngoscopy
Implication:
• Increased risk of
obstruction
• Difficult direct
visualization
Shape of larynx
Management:
• Critical to have
multiple sizes of
ETT
Implication:
• Elliptical shape of
cricoid ring
• ETT may seem
“stuck” just
beyond cords
Harless, J et al. Int J Crit Illn Inj Sci 2014Photo credit: In Coté CJ, Ryan JF, Todres ID, et al [eds]: A
Practice of Anesthesia for Infants and Children.
Physiologic Immaturity
Management:
• Expect rapid desaturation during
apnea
• Early O2, preoxygenation
• Light sedation just prior to
induction can be beneficial
Implication:
• Higher O2 consumption
• Smaller tidal volumes
• Lower FRC
• Higher RR
Predicting difficulty in the
pediatric airway
Incidence of laryngoscopy difficulty in children:
0.1% to 3.5%
• Age < 1 year
• Cardiac anomaly
• Congenital ear malformations
• Cleft palate
• Low BMI
• + usuals
Harless, J et al. Int J Crit Illn Inj Sci 2014
Looks Like
Your Throat
Could Use
Some Plastic:
Preparing for intubation
Considerations Before the
Drugs
• Pre-oxygenation
• Consider nasal cannula for apneic
oxygenation: Low-flow O2 (2-5LPM)
• Consider delayed sequence intubation (DSI)
• Highly anxious children
• Craniofacial abnormalities
• How’s your BMV?
Don’t Be This Guy . . . Creating an Upper
Airway Obstruction
First Learn Stand. Then Learn Fly
• Mental Miyagi Mantra:
“Lift the mask to the
face, Daniel-San”
• 2-person whenever
possible
• Modify the C-E to a “V
clamp”
Considerations Before the Drugs
• Fill the tank
• Head up 20 degrees
• Have the (ever growing)
equipment smorgesboard
available
Weingart SD et al. Ann Emerg Med 2012
Choose Your Weapons!
Growing number of advanced airway options:
• Microcuffed endotracheal tubes
• Supraglottic devices
• Bougie
• Videolaryngoscopy
Cuffed Endotracheal Tubes
Use a cuffed tube whenever possible:
• Uncuffed tube usage leads to excessive tube
exchange rates approaching 30%
• Difficult to predict the correct size with uncuffed
tubes
• No increased adverse event rate with cuffed tubes
• New micro-cuffed tubes have changed the landscape
Crankshaw D, et al. Pediatr Anesth Crit Care J 2014
Microcuff Endotracheal Tubes
• High volume, low pressure: average
11cm H2O
• Short cuff length when inflated and
expands below the sub-glottis
• No change in capnogram
Rameshwar M, et al. Indian J Anaesth 2015
Tube size: Age in years + 3
4
Photo credit:www.richardsmedical.com
Beyond the DL
Have a supraglottic available for
the difficult airway
• 1st choice in 23% of children
with known difficult airway
• High first-pass success and skill
retention rates
• Short insertion times
Jagannathan N, et al. Br J Anaesth 2014;
Hughes C, et al. Pediatr Anaesth 2012
Photo credit:www.remotemedical.com
Beyond the DL
Bougie is an option, but:
• Tracheal rings can be harder to feel
• Smallest Bougie is 10F, fits over
3.5mm tube
• Need 2 people
Photo credit:www.bay-medical.com
VL in Pediatrics
• Improves laryngoscopic
view in the anticipated
difficult airway
• Faster time to successful
ETI in difficult or after
failed ETI
• Higher first-pass success in
those with little intubating
experience
Pros: Not So Pros:
De. Jong A, et al. Int Care Med 2014; Abdelgadir IS, et al.
Cochrane Data Syst Rev 2017; Sun Y et al. Paediatr Anaesth
2014
• Same hypoxia, hypotension and
airway trauma rates as with DL
• In the typical airway, no
difference in 1st-pass success
between VL and DL
• Time to intubation prolonged
with VL
• Increased rate of intubation
failure
Cocktails Preferred by Children
• Atropine
• Ketamine
• Etomidate
• Rocuronium vs succinylcholine
Atropine
Consider for :
• < 1year of age
• Septic shock or hypovolemic shock
• Patients < 5 years of age receiving succinylcholine or
any child receiving a second dose of succinylcholine
Who will grumble:
• Neurosurgeons - pupils will be dilated
• Respiratory therapists - prevents bradycardic
response to hypoxemia
Jones P, et al. Ped Crit Care Med 2013; Jones P,
et al. Arch Dis Child 2012
Ketamine
Arguably, the ultimate RSI sedative:
• Rapid onset: 30 seconds IV
• Brief duration: 10-15 minutes IV
• Fantastic safety profile
• Neuroprotective role now shown in children
• Respiratory depression and laryngospasm are
rare and manageable
Bar-Joseph G, et al. J Neurosurg Pediatr 2009; Green
SM et al. Ann Emerg Med 2011
Ketamine
The old contraindications have been
proven false:
• Neuroprotective role now shown in
children
• No clinically significant rise in IOP
• Respiratory depression and
laryngospasm are rare and
manageable
Bar-Joseph G, et al. J Neurosurg Pediatr 2009; Green
SM et al. Ann Emerg Med 2011
No longer brings the
“you horrible person”
face
Etomidate
• Reliably maintains hemodynamics and decreases ICP while
maintaining CPP
• Dose 0.3-0.5mg/kg IV for induction
• Not recommended for sepsis, but significant debate remains:
• Single dose doesn’t change 24-hour cortisol levels (or it
does)
• Decrease in vasopressor therapy requirement when
etomidate used (or increased mortality)
• Risk of adrenal suppression +/- negated with steroid
administration
Paralytics
• Onset 30-60 seconds IV
• Duration 30 minutes
• Serious adverse effects:
few
• Reversal agent available
Rocuronium Succinylcholine
• Onset 30-60 seconds IV
• Duration 4-6 minutes IV
• Serious adverse effects:
multiple
• May be preferred in the
difficult airway
What About the Narcs?
• RSI with opioids in children is generally not
recommended
• Increased risk of hypotension, early
respiratory depression that interferes with
preoxygenation
• Provide analgesia as part of post-intubation
care
What to do about those neos?
• Median success rate is doubled
with premedication, regardless
of experience
• Successfully intubated in half
the time
• Fewer changes in baseline
heart rate
Give ‘em drugs!
Le CN, et al. J Perinatol 2014; Bottor LT Adv
Neonatal Care 2009
Cocktails Preferred by Children
For most RSI circumstances:
• Atropine (if < 1 year), Ketamine, Rocuronium
For neonates > 36 weeks:
• Atropine, Fentanyl, Rocuronium
Common Pediatric Airway
Management Pitfalls
Watch that last
step, it’s a
doozy. . .
Common Airway Management
Pitfalls
1. Late recognition of upper airway obstruction
• Tracheal tug, stridor, snoring
• Paradoxical chest wall movement
• Capnography changes
The solution:
• Visualization
• Improve technique
Karsli C. Can J Anesth 2015
Common Airway Management
Pitfalls
Understand the critical importance of jaw thrust
(start video on next slide at 5:45)
Video credit: Kalra A, Tufts Medical Ctr Anesthesia Dept
Common Airway Management
Pitfalls
2. Inadequate sedation/paralytic depth
• Incorrect dosing or failure to redose
• Results in thrashing, breath-holding and partial
obstruction, leading to rapid oxygen desaturation
The solution:
• Ensure correct dosing
• Ensure multiple doses available
• Ensure effect prior to manipulation
Karsli C. Can J Anesth 2015
Common Airway Management
Pitfalls
3. Overly aggressive BMV during and before induction
• Leads to gastric insufflation, reducing lung volumes and
increasing the risk of regurgitation
• Worsens TV
The solution:
• 2-person BMV
• Ventilation timer
• Capnograph
Karsli C. Can J Anesth 2015
Common Airway Management
Pitfalls
4. Suboptimal glottis visualization
Children have anteriorly placed larynx and angled
The solution:
• External laryngeal manipulation
• Optimize head position
• Insert laryngoscope deeply and withdraw slowly
• Change blade type or size
• High reps
Burns BJ. Ann Emerg Med 2017
The Unanticipated Difficult Airway
This is why you:
• Practice BMV
• Have a supraglottic available
• Have a video laryngoscope
• Carry a bougie
• Have reversal agents
• Secure prior to departure when possible
Can’t Ventilate, Can’t Intubate
Needle cricothyrotomy
preferred in children < 12
years of age
Assemble:
• a syringe half-filled with
saline
• A 14- or 16-guage syringe
• 15-mm adapter from a
tracheal tube
Can’t Ventilate, Can’t Intubate
Step 1: Palpate the cricothyroid
membrane: laryngeal prominence
not fully developed in child < 8yoa
Warning: Unless you’re a sharp-
shooter, this is why it is critical to
make needle cric a last resort:
2.6mm x 3mm
Photo Credit: David Low, CHOP,
www.entokey.com
Can’t Ventilate, Can’t Intubate
• Insert the catheter (14-16g)
• Aspirate air to confirm
placement
• Attach tracheal tube adapter
• RR 5-6bpm
• Allows further intubation
attempts if appropriate
Karsli C. Can J Anesth 2015
Can’t Ventilate, Can’t Intubate
If spontaneous respirations:
3) IV
extension set
2) 3-way stopcock
4) 14-16g angio
1) O2 extension
tubing
Summary
• Understand the unique anatomical and physiologic
differences in children and you will increase your
chances of success in pediatric airway management
• A thorough mental check for the risk factors of pediatric
airway difficulty should be part of your 7 Ps
• Know your airway toolbox: optimal drugs, techniques
and equipment
• Be an expert at BMV
Maria.Mandt@childrenscolorado.org
So Long, Cowboy

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Head extension- External laryngeal pressureOperator:- Landmark cricothyroidmembrane- Stabilize needle- Aspirate as you advance- Advance catheter over needle- Attach syringe and ventilateBurns BJ. Ann Emerg Med 2017 Can’t Ventilate, Can’t IntubateSurgical cricothyrotomyAssemble:- Scalpel- Bougie or ETT- Tube or catheterOperator:- Landmark cricothyroid membrane- Make transverse incision through skin andcricothyroid membrane- Insert bougie or ETT and advance- Attach

  • 1. Pediatric Airway Management: Leave the Cowboy Hat Behind Maria J. Mandt, MD Associate Professor of Pediatrics Medical Director of EMS Medical Director Flight For Life, Children’s Hospital Colorado Team
  • 2. I have no relevant financial disclosures Quality is not an act. It is a habit. - Aristotle
  • 3. • Discuss the clinically relevant differences between the pediatric and adult airways • Identify predictors of a difficult pediatric airway • Formulate a plan in the event of an unanticipated difficult pediatric intubation Time to Talk Objectives, Cowboy Photo credit: www.theredlist.com
  • 4. Low incidence, high risk. . . CCT intubation statistics: • 1.3% of trips involve peds/neo intubation • Difficult airway predictors present in 77% • Neonatal 1st-pass success rate: 59.3% • Neonatal 1st-pass success without hypoxia or hypotension: 30.8% • Pediatric 1st-pass success rate: 81.7% • Pediatric 1st-pass success rate without hypoxia or hypotension: 60.7% What should we take away from these numbers? Burns BJ et al. Ann Emerg Med 2017; Reichert, RJ et al. Prehosp Emerg Care 2018
  • 5. Scared now? You Need a Plan Photo credit: https://www.youtube.com/watch?v=DwzCrhth090
  • 6. If you climb in the saddle, be ready for a ride. . . . Learn the 7 Ps of Preparation: Prior Proper Planning Prevents Piss Poor Performance Photo credit: www.coburgbanks.co.uk
  • 7. Oh, baby. . . Let me count the ways Critical differences between the big and the small
  • 8. Prominent occiput Management: • Shoulder roll for all < 8 years of age Implication: • Neck flexion causes UAO • O/P/L axes not aligned, making laryngoscopy difficult Photo credit: JEMS.com,
  • 9. Cephalad Larynx Implication: • Shorter distance between tongue and epiglottis creates acute angle • Larynx seems more anterior Management: • Optimal positioning • Gentle cricoid Photo credit: www.youtube.com/watch?v=EIty86wXmB8
  • 10. Epiglottis angled over vocal cords Implication: More difficult to lift epiglottis and visualize VC ETT can get caught on anterior commissure of VC Management: • Gentle cricoid • Straight blade in children under 3 Pediatric Adult
  • 11. Significant soft tissue and large tongue Management: • OPA • Lateral approach to laryngoscopy Implication: • Increased risk of obstruction • Difficult direct visualization
  • 12. Shape of larynx Management: • Critical to have multiple sizes of ETT Implication: • Elliptical shape of cricoid ring • ETT may seem “stuck” just beyond cords Harless, J et al. Int J Crit Illn Inj Sci 2014Photo credit: In Coté CJ, Ryan JF, Todres ID, et al [eds]: A Practice of Anesthesia for Infants and Children.
  • 13. Physiologic Immaturity Management: • Expect rapid desaturation during apnea • Early O2, preoxygenation • Light sedation just prior to induction can be beneficial Implication: • Higher O2 consumption • Smaller tidal volumes • Lower FRC • Higher RR
  • 14. Predicting difficulty in the pediatric airway Incidence of laryngoscopy difficulty in children: 0.1% to 3.5% • Age < 1 year • Cardiac anomaly • Congenital ear malformations • Cleft palate • Low BMI • + usuals Harless, J et al. Int J Crit Illn Inj Sci 2014
  • 15. Looks Like Your Throat Could Use Some Plastic: Preparing for intubation
  • 16. Considerations Before the Drugs • Pre-oxygenation • Consider nasal cannula for apneic oxygenation: Low-flow O2 (2-5LPM) • Consider delayed sequence intubation (DSI) • Highly anxious children • Craniofacial abnormalities • How’s your BMV?
  • 17. Don’t Be This Guy . . . Creating an Upper Airway Obstruction
  • 18. First Learn Stand. Then Learn Fly • Mental Miyagi Mantra: “Lift the mask to the face, Daniel-San” • 2-person whenever possible • Modify the C-E to a “V clamp”
  • 19. Considerations Before the Drugs • Fill the tank • Head up 20 degrees • Have the (ever growing) equipment smorgesboard available Weingart SD et al. Ann Emerg Med 2012
  • 20. Choose Your Weapons! Growing number of advanced airway options: • Microcuffed endotracheal tubes • Supraglottic devices • Bougie • Videolaryngoscopy
  • 21. Cuffed Endotracheal Tubes Use a cuffed tube whenever possible: • Uncuffed tube usage leads to excessive tube exchange rates approaching 30% • Difficult to predict the correct size with uncuffed tubes • No increased adverse event rate with cuffed tubes • New micro-cuffed tubes have changed the landscape Crankshaw D, et al. Pediatr Anesth Crit Care J 2014
  • 22. Microcuff Endotracheal Tubes • High volume, low pressure: average 11cm H2O • Short cuff length when inflated and expands below the sub-glottis • No change in capnogram Rameshwar M, et al. Indian J Anaesth 2015 Tube size: Age in years + 3 4 Photo credit:www.richardsmedical.com
  • 23. Beyond the DL Have a supraglottic available for the difficult airway • 1st choice in 23% of children with known difficult airway • High first-pass success and skill retention rates • Short insertion times Jagannathan N, et al. Br J Anaesth 2014; Hughes C, et al. Pediatr Anaesth 2012 Photo credit:www.remotemedical.com
  • 24. Beyond the DL Bougie is an option, but: • Tracheal rings can be harder to feel • Smallest Bougie is 10F, fits over 3.5mm tube • Need 2 people Photo credit:www.bay-medical.com
  • 25. VL in Pediatrics • Improves laryngoscopic view in the anticipated difficult airway • Faster time to successful ETI in difficult or after failed ETI • Higher first-pass success in those with little intubating experience Pros: Not So Pros: De. Jong A, et al. Int Care Med 2014; Abdelgadir IS, et al. Cochrane Data Syst Rev 2017; Sun Y et al. Paediatr Anaesth 2014 • Same hypoxia, hypotension and airway trauma rates as with DL • In the typical airway, no difference in 1st-pass success between VL and DL • Time to intubation prolonged with VL • Increased rate of intubation failure
  • 26. Cocktails Preferred by Children • Atropine • Ketamine • Etomidate • Rocuronium vs succinylcholine
  • 27. Atropine Consider for : • < 1year of age • Septic shock or hypovolemic shock • Patients < 5 years of age receiving succinylcholine or any child receiving a second dose of succinylcholine Who will grumble: • Neurosurgeons - pupils will be dilated • Respiratory therapists - prevents bradycardic response to hypoxemia Jones P, et al. Ped Crit Care Med 2013; Jones P, et al. Arch Dis Child 2012
  • 28. Ketamine Arguably, the ultimate RSI sedative: • Rapid onset: 30 seconds IV • Brief duration: 10-15 minutes IV • Fantastic safety profile • Neuroprotective role now shown in children • Respiratory depression and laryngospasm are rare and manageable Bar-Joseph G, et al. J Neurosurg Pediatr 2009; Green SM et al. Ann Emerg Med 2011
  • 29. Ketamine The old contraindications have been proven false: • Neuroprotective role now shown in children • No clinically significant rise in IOP • Respiratory depression and laryngospasm are rare and manageable Bar-Joseph G, et al. J Neurosurg Pediatr 2009; Green SM et al. Ann Emerg Med 2011 No longer brings the “you horrible person” face
  • 30. Etomidate • Reliably maintains hemodynamics and decreases ICP while maintaining CPP • Dose 0.3-0.5mg/kg IV for induction • Not recommended for sepsis, but significant debate remains: • Single dose doesn’t change 24-hour cortisol levels (or it does) • Decrease in vasopressor therapy requirement when etomidate used (or increased mortality) • Risk of adrenal suppression +/- negated with steroid administration
  • 31. Paralytics • Onset 30-60 seconds IV • Duration 30 minutes • Serious adverse effects: few • Reversal agent available Rocuronium Succinylcholine • Onset 30-60 seconds IV • Duration 4-6 minutes IV • Serious adverse effects: multiple • May be preferred in the difficult airway
  • 32. What About the Narcs? • RSI with opioids in children is generally not recommended • Increased risk of hypotension, early respiratory depression that interferes with preoxygenation • Provide analgesia as part of post-intubation care
  • 33. What to do about those neos? • Median success rate is doubled with premedication, regardless of experience • Successfully intubated in half the time • Fewer changes in baseline heart rate Give ‘em drugs! Le CN, et al. J Perinatol 2014; Bottor LT Adv Neonatal Care 2009
  • 34. Cocktails Preferred by Children For most RSI circumstances: • Atropine (if < 1 year), Ketamine, Rocuronium For neonates > 36 weeks: • Atropine, Fentanyl, Rocuronium
  • 35. Common Pediatric Airway Management Pitfalls Watch that last step, it’s a doozy. . .
  • 36. Common Airway Management Pitfalls 1. Late recognition of upper airway obstruction • Tracheal tug, stridor, snoring • Paradoxical chest wall movement • Capnography changes The solution: • Visualization • Improve technique Karsli C. Can J Anesth 2015
  • 37. Common Airway Management Pitfalls Understand the critical importance of jaw thrust (start video on next slide at 5:45) Video credit: Kalra A, Tufts Medical Ctr Anesthesia Dept
  • 38. Common Airway Management Pitfalls 2. Inadequate sedation/paralytic depth • Incorrect dosing or failure to redose • Results in thrashing, breath-holding and partial obstruction, leading to rapid oxygen desaturation The solution: • Ensure correct dosing • Ensure multiple doses available • Ensure effect prior to manipulation Karsli C. Can J Anesth 2015
  • 39. Common Airway Management Pitfalls 3. Overly aggressive BMV during and before induction • Leads to gastric insufflation, reducing lung volumes and increasing the risk of regurgitation • Worsens TV The solution: • 2-person BMV • Ventilation timer • Capnograph Karsli C. Can J Anesth 2015
  • 40. Common Airway Management Pitfalls 4. Suboptimal glottis visualization Children have anteriorly placed larynx and angled The solution: • External laryngeal manipulation • Optimize head position • Insert laryngoscope deeply and withdraw slowly • Change blade type or size • High reps Burns BJ. Ann Emerg Med 2017
  • 41. The Unanticipated Difficult Airway This is why you: • Practice BMV • Have a supraglottic available • Have a video laryngoscope • Carry a bougie • Have reversal agents • Secure prior to departure when possible
  • 42. Can’t Ventilate, Can’t Intubate Needle cricothyrotomy preferred in children < 12 years of age Assemble: • a syringe half-filled with saline • A 14- or 16-guage syringe • 15-mm adapter from a tracheal tube
  • 43. Can’t Ventilate, Can’t Intubate Step 1: Palpate the cricothyroid membrane: laryngeal prominence not fully developed in child < 8yoa Warning: Unless you’re a sharp- shooter, this is why it is critical to make needle cric a last resort: 2.6mm x 3mm Photo Credit: David Low, CHOP, www.entokey.com
  • 44. Can’t Ventilate, Can’t Intubate • Insert the catheter (14-16g) • Aspirate air to confirm placement • Attach tracheal tube adapter • RR 5-6bpm • Allows further intubation attempts if appropriate Karsli C. Can J Anesth 2015
  • 45. Can’t Ventilate, Can’t Intubate If spontaneous respirations: 3) IV extension set 2) 3-way stopcock 4) 14-16g angio 1) O2 extension tubing
  • 46. Summary • Understand the unique anatomical and physiologic differences in children and you will increase your chances of success in pediatric airway management • A thorough mental check for the risk factors of pediatric airway difficulty should be part of your 7 Ps • Know your airway toolbox: optimal drugs, techniques and equipment • Be an expert at BMV