Shatavari, Shatavarichurna,
Shatavariguggulu, Shatavarisiddha
9 Shatavari
Department of Dravyaguna
26
1/17/2019
Analgesic and anti-inflammatory activity of Asparagus
racemosus Willd root extracts in experimental animal models
International Journal of Green Pharmacy (IJGP)
Conclusion-
The ethanolic extract of Asparagus racemosus root showed significant
analgesic activity in acetic acid induced writhing, tail immersion and hot
plate tests in mice.
The extract also exhibited significant anti-inflammatory activity in
carrageenan induced rat p
the concept of virya gives the knowledge of potency of drugs it is well explained by Virya. the action of the drugs depends on the potency presents in it.
the concept of virya gives the knowledge of potency of drugs it is well explained by Virya. the action of the drugs depends on the potency presents in it.
in ayurvedic pharmacology some drugs have action according to their aura. this aura treat patients in various aspects eg wearing of jems and different stones
A Guest lecture organised by Agnivesha Ayurveda Academy Bangalore; have invited to Dr. Lohith B. A. M.D., PhD. Head & Professor, Department of Panchakarma , SDM college of Ayurveda & Hospital, Hassan
To deliver the lecture on "Panchakarma and its advancement" on 27/04/2017
As a matter of fact basti is the most important item among the samshodhana procedures. However the term basti is derived from the fact that the basti yantra or the apparatus used for introducing the medicated materials is made up of basti or animal urinary bladder. Generally a basti is applied through the rectum though it may also be applied for urethra. In such cases the term Uttara basti is applied.
Depending upon the use of different drugs, basti effects samshodhana of doshas. It has also samshamana effects. Thus basti in its different forms has very wide application.
Ksheerabala Taila is a classical ayurvedic medicine manufactured using Bala, Milk and Tila taila which helps in conditions like sciatica, arthritis, lowbackache, cervical spondylosis, facial paralysis and as a rasayana (rejuvenation).
the ppt gives detailed knowledge of Karma that are described in Ayurveda Dravyaguna (Ayurvedic Materia medica) it is useful to treat the patients by Ayurvedic way.
in ayurvedic pharmacology some drugs have action according to their aura. this aura treat patients in various aspects eg wearing of jems and different stones
A Guest lecture organised by Agnivesha Ayurveda Academy Bangalore; have invited to Dr. Lohith B. A. M.D., PhD. Head & Professor, Department of Panchakarma , SDM college of Ayurveda & Hospital, Hassan
To deliver the lecture on "Panchakarma and its advancement" on 27/04/2017
As a matter of fact basti is the most important item among the samshodhana procedures. However the term basti is derived from the fact that the basti yantra or the apparatus used for introducing the medicated materials is made up of basti or animal urinary bladder. Generally a basti is applied through the rectum though it may also be applied for urethra. In such cases the term Uttara basti is applied.
Depending upon the use of different drugs, basti effects samshodhana of doshas. It has also samshamana effects. Thus basti in its different forms has very wide application.
Ksheerabala Taila is a classical ayurvedic medicine manufactured using Bala, Milk and Tila taila which helps in conditions like sciatica, arthritis, lowbackache, cervical spondylosis, facial paralysis and as a rasayana (rejuvenation).
the ppt gives detailed knowledge of Karma that are described in Ayurveda Dravyaguna (Ayurvedic Materia medica) it is useful to treat the patients by Ayurvedic way.
Development and Evaluation of Enteric Coated Herbal Drug Delivery System for ...iosrphr_editor
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
Evaluation of Analgesic Activity of Moringa Oleifera Lam. Stem Bark Extract b...QUESTJOURNAL
Abstract: Moringa oleifera Lam. is also known as ‘Miracle tree’ because of its uses of all parts particularly for their great potential in pharmacological, nutritional and water purification aspects. The study has been done for the phytochemical screening and analysis of analgesic potential of Moringa olifiera Lam. methanolic stem bark extract using Acetic acid induced Writhing method. Qualitative chemical analysis was carried out through phytochemical investigation which indicated the presence of carbohydrates, glycosides, saponins, flavonois, tannins, proteins, alkaloids etc. in the extracts. To study analgesic activity Acetic acid induced Writhing test was used, where Methanolic stem bark extract was introduced intraperitonially at doses of 150 mg/kg and 300 mg/kg to Swiss-albino mice. The dose of 300 mg/kg showed significant inhibition of Writhing response created by acetic acid in a dose dependent manner when compared to the standard control drug Diclofenac Sodium. Those two different doses exhibited 5% and 80% inhibition in writhing response respectively while the Diclofenac Na inhibited about 46.25% of writhing response at a dose of 40 mg/kg of body weight. The results of this study support the potential pain management therapy using this crude extract.
This slide gives brief information about medicinal, plant Cassia fistula (rajbriksha). It consist of information about Macroscopy, Chemical constituents and Medicinal uses of Cassia fistula plant................Hope, This will Help You........Have a Wonderful Day....
A Critical analysis of properties of Mahadalu Anupana in Ayurvedic and modern...Sandamalie Ranasinghe
Anupana is a substance which is used in conjunction with the drug to enhance its effects. Mahadalu Anupana of Chandra Kalka is a type of Dalu Anupana which is quite popular among traditional medical fraternity. The exploratory study was directed towards the compilation of the pharmacological attributes of medicinal plants used in Mahadalu Anupana.
Phytochemical, Antioxidant and Antibacterial Studies on Bambusa arundinacea a...SUS GROUP OF INSTITUTIONS
This study was formulated to check the phytochemical, antioxidant, antibacterial potential of
Bambusa arundinacea (Bamboo) and Mangifera indica (Mango) trees. Aqueous, ethanolic and
methanolic extracts were prepared from leaves of former and stem bark of later. The phytochemical
screening of the extracts showed the presence of various bioactive compounds such as
carbohydrates, flavonoids, saponins and proteins in B. arundinacea, alkaloids, flavonoids, tannins,
saponins, steroids and cardiac glycosides in M. indica. Total phenolic concentration and
percentage of free radical scavenging activity was more in ethanolic extracts of B. arundinacea and
M. indica followed by methanolic extracts and aqueous extracts. Highest percentage of ferric
reducing antioxidant power was found in ethanolic extracts and lowest in aqueous extracts indicates
that ethanolic extracts has more antioxidant potential than the other two extracts. Ethanolic extracts
of both plants had higher inhibition on the tested Gram positive (B. subtilis & S. aureus) as well as
Gram negative (E.coli & P. aeruginosa) bacteria evidenced from the zones of inhibition. M. indica
showed more therapeutic potential as compared to B. arundinacea and ethanolic as well as
methanolic extracts of both the tested plants were more effective than aqueous extracts due to better
extraction power of organic solvents. Overall study indicates that B. arundinacea and M. indica are
potential source of natural antioxidants, phytochemicals and antibacterials that can be used for the
development of novel drugs and may represent new source of antimicrobials with stable, biologically
active components that can establish a scientific base for further use in modern medicines.
Comparative Effect of Aqueous and Methanol Extract of Buchholzia Coriacea ...Scientific Review SR
This study was designed to investigate the comparative effect of aqueous and methanol extract
of Buchholzia coriacea seeds on carrageenan-induced inflammation in rats. Twenty four albino rats of both
sexes weighing 162.53±3.55 g were used. For the aqueous extract, 12 animals were divided into 4 groups of 3
rats each. Animals in group 1 (positive control) were administer ed 0.5 ml of diclofenac sodium (reference
anti-inflammatory drug) while those in group 2, 3 and 4 were administered 100, 300 and 500 mg/kg body
weight of the aqueous extract of Buchholzia coriacea seeds respectively. For the methanol extract, 12 animals
were divided into 4 groups of 3 rats each. Animals in group 1 (positive control) were administered 0.5 ml of
diclofenac sodium (reference anti-inflammatory drug) while those in group 2, 3 and 4 were administered 100,
300 and 500 mg/kg body weight of the methanol extract of Buchholzia coriacea seeds respectively. Thirty
minutes after treatment of animals in both the aqueous and methanol groups with the drug and extract, 0.2 ml
of 2% carrageenan was injected into the left hind paw of each animal under the sub plantar aponeurosis. Paw
volume of rats were measured before and after carrageenan injection at 30 minutes interval over a period of 3
hours (30, 60, 90, 120, 150 and 180) minutes, to determine the anti -inflammatory response of both extracts,
using carrageenan-induced paw odema method. Preliminary phytochemical screening revealed that the
aqueous extract contains terpenoids, flavonoids and steroids while the methanol extract contains saponins,
flavonoids, tannins, anthraquinones, cardiac glycosides, terpeno ids and steroids. Proximate analysis of
Buchholzia coriacea seeds revealed that crude fibre has the lowest percentage of (1.10±0.05), ash content
(5.20±0.01), crude fat (4.10±0.02) moisture content (9.10±0.13), crude protein (10.20±0.20) and
carbohydrate with the highest percentage of (70.10±0.04). In terms of percentage inhibition, paw volume was
brought to near normal levels by the methanol extract at 100 and 300 mg/kg body weight which showed
better anti-inflammatory activity than 500 mg/kg body weight o f the same extract as well as all doses of the
aqueous extract and even more than the reference drug. Overall, the anti -inflammatory effect may be traced
to single or synergistic activity of phytoconstituents present in the methanol extract.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Read| The latest issue of The Challenger is here! We are thrilled to announce that our school paper has qualified for the NATIONAL SCHOOLS PRESS CONFERENCE (NSPC) 2024. Thank you for your unwavering support and trust. Dive into the stories that made us stand out!
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty,
International FDP on Fundamentals of Research in Social Sciences
at Integral University, Lucknow, 06.06.2024
By Dr. Vinod Kumar Kanvaria
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Advantages and Disadvantages of CMS from an SEO Perspective
Pain management
1. TOP 10 DRUGS PRACTICISED
IN PAIN MANAGEMENT
BY:-
DR.MAHENDRA PRASAD
YADAV
2. DRAVYA PRAYOGA IN APASMARA
Presented by
Dr. Mahendra Pd. Yadav
II Year PG Scholar
Guided by
Dr. Prakash L. Hegde
Professor & HOD
Department of Dravyguna
SDM College of Ayurveda and Hospital, Hassan
TOP 10 DRUGS PRACTICISED IN PAIN
MANAGEMENT
2
3. CONTENT
1.INTRODUCTION
Definition of Pain
Types
2 DRAVYA PRAYOGA IN PAIN MANAGEMENT
Single Drugs with Research Articles
3.DISCUSSION
4.CONCLUSION
5.REFERENCES
Department of Dravyaguna
3
1/17/2019
4. 1. INTRODUCTION OF PAIN
The International Association for the study of pain
(IASP) has defined pain as-
‘an unpleasant sensory and emotional
experience associated with actual or potential tissue
damage or described in terms of such damage’.
Department of Dravyaguna
4
1/17/2019
5. PAIN
Most of patient will come to doctor
with pain as main symptom.
Pain is
mentioned in
classic as
Vedana/Shoola
/Arti/Ruja etc.
Vedanasthapana is famous group of drugs for pain
management. So purpose of this study is to review the
pharmacological actions of Top 10 herbs based on research
work
20% of adults
suffer from pain
globally and 10%
are newly
diagnosed with
chronic pain each
year.
Department of Dravyaguna
5
1/17/2019
6. TYPES OF PAIN
PainACUTE CHRONIC
Nociceptive pain
Neuropathic pain
Department of Dravyaguna
6
1/17/2019
7. ANALGESICS
The drugs which possess significant pain
relieving properties by acting
in the central nervous system , or
on the peripheral pain receptors
without significantly affecting consciousness.
Analgesics which also includes
Anti inflammatory drugs,
Opioid analgesics,
Antidepressants and
Anticonvulsants.
Department of Dravyaguna
7
1/17/2019
9. B.N.:- Saraca indica Linn
Family:-Caesalpinaceae
Rasa:-Kashaya, Tikta
Guna:- Laghu, Ruksha
Veerya:-Sheeta
Vipaka:-Katu
Doshakarma:-Kaphapitta Samaka
Use parts:-Bark, Seed & Flowers
Chemical compositions:-Alkaloids and
Steroids
Aamayika Prayoga:-
Ashoka ghrita is used in Vatavyadhi
(Disorder of Vata), Yonishoola and
Katishoola.(SS.Ci 4.27) 2.
Yoga:- Ashokaghrita, Ashokarist, Ashoka
kashaya, Mahamarichyadya Taila
Ashoka1
Department of Dravyaguna
9
1/17/2019
10. Experimental evaluation of analgesic property
of bark of Saraca indica Linn (Ashoka )
INTERNATIONAL JOURNAL OF AYURVEDA & ALTERNATIVE MEDICINE eISSN-
2348-0173 pISSN-2395-3985 Vol-5 ISSUE 2 (2017)
Priyanka A. Shine1*, Vimala. K. S.2, Priyalatha B.3, Nayana Raj4, Sreelekshmi M.5
Conclusion-
The aqueous and alcoholic extracts of bark of
Saraca indica (Ashoka) showed significant
analgesic activity at 300 mg/ Kg body weight in
Swiss albino rats in the presence of alkaloids and
steroids .
Department of Dravyaguna
10
1/17/2019
12. ANTI-INFLAMMATORY ACTIVITY OF WILD AND
CULTIVATED VARIETIES OF ERANDA (RICINUS
COMMUNIS LINN.) ROOT
International Journal of Ayurveda and Pharma Research
Doshi Krunal A1*, Acharya Rabinarayan2, Ravishankar B3, Nariya Mukesh B4
Conclusion:-
Decoction of wild variety, of Ricinus communis L. root provided
considerable suppression of carrageenan induced paw edema
compared to its cultivated variety.
Medicinal properties in plants are mainly due to the presence of
Alkaloids to be responsible for Anti-inflammatory activity.
Department of Dravyaguna
12
1/17/2019
13. B.N.:-Commiphora mukul Hook ex. Stocks
Family:-Burseraceae
Rasa:-Tikta, Katu, Madhura, Kashaya
Guna: Tikshana, Sara, Sukshama, Snigdha,
Laghu, Vishada
Veerya:-Ushna
Vipaka:-Katu
Doshakarma:-Tridosh Samaka
Vata shamaka, Pittakaphahara.
Use parts:-:Gum resin
Chemical compositions: Carbohydrate,
Alkaloids,Convoline,Convolidie,Convovine.
Aamayika Prayoga:
Guggulu is the best remedy for vata covered by
medas.(AH.U.40/48)
Yoga:-Trayodasanga guggulu, Mahayogaraja
guggulu, Triphala guggulu, Vatari guggulu
3 Guggulu
Department of
Dravyaguna
13
1/17/2019
14. Comparison of the anti-inflammatory activity of Commiphora
mukul (an indigenous drug) with those of phenylbutazone and
ibuprofen in experimental arthritis induced by mycobacterial
adjuvant.
Arzneimittel-Forschung [01 Jul 1977, 27(7):1455-1457]
Sharma JN , Sharma JN
Conclusion-
Inflammatory syndrome, resembling rheumatoid
arthritis in man, was induced in the right hock joint of
albino rabbits by intra-articular injection of the killed
mycobacterial adjuvant in liquid paraffin.
Development of this arthritic syndrome was studied
from a period of five months with and without drugs.
Department of Dravyaguna
14
1/17/2019
15. Department of Dravyaguna
15
Anti-inflammatory agents such as phenylbutazone,
ibuprofen and fraction "A" of gum-guggulu from
Commiphora mukul were administered orally at a daily
dose of 100, 100 and 500 mg/kg, respectively, for a period
of five months.
All three drugs decreased the thickness of the joint
swelling during the course of drug treatment.
These results indicate the beneficial role of
phenylbutazone, ibuprofen and fraction "A" of gum-guggulu
in experimental arthritis.
1/17/2019
16. B.N:-Anthocephalus cadamba Roxb
Family:-Rubiaceae
Rasa:- Madhura, Tikta, Kashaya
Guna:-Ruksha
Veerya:-Sheeta
Vipaka:-Katu
Prabhava:-Vedanasthapana
Doshakarma:-Vatapitta shamaka
Use parts:-Bark,Fruit, Leaf
Chemical compositions:-alkaloids like
Cadambine, Cadamine, Cadambagenic
acid, Quinovic acid
Aamayika Prayoga:-
For covering wounds, the leaves of
kadamba, arjuna, nimba,patala,and
ashwatha should be used.(CS.Ci25/95)
Yoga:-Nyogradhadi Kwatha,
Kadambadi Kwatha
4 Kadamba
Department of Dravyaguna
16
1/17/2019
17. Evaluation of the Analgesic and Anti inflammatory Activity of
Kadamba(Anthocephalus cadamba Roxb.) an experimental study
Dissertation by Dr. Prakash L Hegde, submitted to the RGUHS
Used model- hot plate method
Conclusion-
Alcoholic extracts of Kadamba has potent analgesic and
anti-inflammatory activity alomost like standard drug.
The kadamba is a freely available safe drug showing
efficacy in single use both in extract and kasaya form on
rats. Same has to be reconfirmed on human beings.
Department of Dravyaguna
17
1/17/2019
18. B.N.:-Myrica esculenta Buch-Ham
Family:-Myricaceae
Rasa:- Kashaya, Tikta, Katu
Guna:-Laghu,Tikshna,
Veerya:-Usana
Vipaka:-Katu
Doshakarma:-Kaphavata samaka
Use parts:-Bark, Flowers
Chemical compositions:-
Glycoside, myricitrin, myrecetin
Yoga:-Saubhagya Sunthi,
Pushyanuga Churna, Kataphaladi
Kwatha
5 Kataphala
Department
of
18
1/17/2019
19. Analgesic and anti-inflammatory activity of ethanolic
extract of stem bark of Myrica esculenta”
Vol-5 ISSUE 2 (2017) INTERNATIONAL JOURNAL OF AYURVEDA & ALTERNATIVE MEDICINE eISSN-2348-
0173 pISSN-2395-3985
Priyanka A. Shine1*, Vimala. K. S.2, Priyalatha B.3, Nayana Raj4, Sreelekshmi M.5
Conclusion-:
The pharmacological screening revealed that MNSBEE
significantly increased pain latency in acetic acid- induced
writhing and hot plate in mice and significantly inhibited
paw edema volume in carrageenan- induced paw edema
and significantly inhibited granuloma weight in cotton
pellet granuloma model at the doses of 400 and 200
mg/kg, p.o.
The combination of MNSBEE and diclofenac has been
studied and found to be most significant analgesic and
anti- inflammatory effect without toxic effect.Department of Dravyaguna
19
1/17/2019
20. B.N.:-Vitex negundo Linn.
Family:-Verbenaceae
Rasa:-Katu, Tikta
Guna:-Laghu, Ruksha
Veerya:-Ushna
Vipaka:-Katu
Doshakarma:-Kapha vata samaka
Use parts: Leaves, Roots, Seeds, Flowers
Chemical compositions:-alkaloids, tannins,
flavonoids, saponins and glycosides.
Aamayika Prayoga:-The drug is an effective
analgesic and anti-inflammatory herbal
agent.
The nirgundi oil is locally applied to
inflammed and painful conditions of
organs, rheumatism, vatavyadhi, sprain,
trauma, wounds earache, headache,
neuritis, sciatica etc.
Yoga:-Nirgundyerandadi Kashaya,Nirgundi
Taila, Nirgundi ghrita
6 Nirgundi
Department of
20
1/17/2019
21. ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES
OF VITEX NEGUNDO (LEAVES) EXTRACT
Pooja Solanki Mishra*, S. Vyas, RP Agrawal, P. Phadnis and A. Tiwari
Department of Pharmacology, M.G.M. Medical College, AB Road, Indore, (M.P.), 452001, India.
Results: In comparison to control group VNE showed highly significant, dose
dependent analgesic activity against chemically as well as thermally induced
pain models (P < 0.05). In comparison to control, VNE at the employed doses
produced marked acute anti-inflammatory activity in rats (P < 0.05).
Conclusions:
The results suggest that the aqueous extract of Vitex negundo has significant
analgesic and anti-inflammatory potential as reflected by the parameters
investigated. Further investigations are however necessary to explore
mechanism(s) of action involved in these pharmacological activities
21
22. B.N.:-Pluchea lanceolata C .B. Clarke
Family:-Asteraceae
Rasa:Tikta
Guna:-Guru
Veerya:-Usana
Vipaka:-Katu
Doshakarma:-Kaphavata samaka
Use parts:-:Leaves
Chemical compositions:-Quercertin,
isorhamnetin, pluchine
Aamyika Prayoga:-
Rasna churna or kwatha is useful and
best in case of
Vatavyadhi.(C.S.Su.25/40)
Yoga:-Rasnadi Gutika, Rasanadi Churna,
Rasnasaptaka Kwatha, Rasnadilepa,
Rasnapanchakam
7 Rasna
Department of Dravyaguna
22
1/17/2019
23. Department of Dravyaguna
23
Conclusion:-
The results of the present study indicate that the
ethanol extracts of Pluchea lanceolata has anti-
inflammatory activity in mice(200mg/kg) and
rats(100mg/kg), which was further localized in the
hexane fraction, from which taraxasterol was
isolated which proved to be one of the active
constituents.
1/17/2019
24. B.N.:Shorea robusta Gaertn.
Family:-Dipterocarpeae
Rasa:-Kashaya
Guna:-Rukshya
Veerya:- Sheeta
Vipaka:-Katu
Prabhava:-Vedanasthapana
Doshakarma:-Kaphapitta nasaka
Use parts:-Bark, Gum-resin
Chemical compositions:-.Pentosans,
lignan, tannin, amino acids and fatty
acids.
Yoga:-Raladi lepa, Raladi dhupa,
Sarjarasadi Malahara
8 Shala
Department of Dravyaguna
24
1/17/2019
25. Analgesic activity of the ethanolic extract of Shorea
robusta Gaertn. (SRE) in experimental animals
Conclusion-
The extract produced significant central
and peripheral analgesic effects, which
was evident from increase in reaction time
in hot plate and tail flick tests, inhibition
in writhing counts in acetic acid-induced
writhing test .
Department of Dravyaguna
25
1/17/2019
INTERNATIONAL JOURNAL OF AYURVEDA & ALTERNATIVE MEDICINE eISSN-2348-0173 pISSN-2395-398 Vol-5
ISSUE 2 (2017) 5
Priyanka A. Shine1*, Vimala. K. S.2, Priyalatha B.3, Nayana Raj4, Sreelekshmi M.5
26. B.N.:Asparagus racemosus Willd
Family:- Liliaceae
Rasa:-Madhura,Tikta
Guna:-Guru,Snigdha
Veerya:-Sheeta
Vipaka:-Madhura
Doshakarma:-Vatapitta samaka
Use parts:-:Roots.
Chemical compositions:
Shatavarin,Saponins, Glycosides of
quercetin Carbohydrate.
Aamayika Prayoga:- It is used in
atisara, rakta aamatisara, apasmara
and shotha
Yoga:-Satavari Modaka, Satavari
Mandura, Satavari Taila, Satavari
Ghrita,
9 Shatavari
Department of Dravyaguna
26
1/17/2019
27. ANALGESIC ACTIVITY OF AQUEOUS AND ALCOHOL ROOT
EXTRACTS OF ASPARAGUS RACEMOSUS WILLD.
Pharmacology online 2: 558-562 (2011) ewsletter Rahiman et al.
Fasalu Rahiman O.M*, Bodapati Srilatha, Rupesh Kumar M, Mohamed iyas k,
Satya Kumar B, Phaneendra P
Result:-. No toxic effects or mortality were
observed with doses ranging from 50mg/kg to
1g/kg for four weeks.
The results of present study indicate the
aqueous and alcohol root extracts of Asparagus
racemosus willd., Possesses analgesic effect in
the presence of alkaloids, carbohydrates,
phytosterols, tannins, flavonoids. Both extracts
showed the analgesic activity .
Department of Dravyaguna
27
1/17/2019
28. B.N.:Albizzia lebbeck Benth
Family:- Mimoseae
Rasa:-Kashaya,Tikta, Katu.
Guna:-Laghu,Ruksha,Tikshana
Veerya:-Isada Ushna
Vipaka:-Katu
Doshakarma:-Tridosahara
Use parts:-Bark, Seeds, Leaves, Flowers
Chemical compositions:-Bark contains
tannin 7-11% and saponin.
Aamayika Prayoga:-The seeds of
shirisha are applied locally in swelling
(sotha).
The snuff of seeds of shirisha and
mulaka (radish) is prescribed in
treatment of shirashula(headache)
(SS, Uttarara 86-31)
Yoga:-Shirishararista, Shirishabijadi Lepa
10 SHIRISHA
28
Department of Dravyaguna
1/17/2019
29. The peripheral analgesic activity of Shirisha was
measured by the acetic acid induced writhing test
INTERNATIONAL JOURNAL OF AYURVEDA & ALTERNATIVE MEDICINE eISSN-2348-0173 pISSN-2395-398 Vol-5
ISSUE 2 (2017) 5
Priyanka A. Shine1*, Vimala. K. S.2, Priyalatha B.3, Nayana Raj4, Sreelekshmi M.5
Conclusion-The crude extract produced 61.48%
(p<0.001) elongation of tail flicking time 30 min after
oral dose of 400mg/kg. The plant extract showed
prolonged stress tolerance capacity in the mice,
indicating the possible involvement of higher centres.
The bark administered in a dose of 250mg/kg
showed analgesic activity slightly less than that of
novalgin.
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30. 3.Discussion
The term Vedana implies sensations. Therefore the
usage of Vedanasthapana drugs not be restricted to
the domain of pain killers; instead it would be
extended to all the disorders which causes
impairments in the sensory perception.
Analgesics includes Anti inflammatory drugs, Opioid
analgesics, Anti depressants and Anticonvulsants.
Vedanasthapana drugs may bring the normal
sensation of wellbeing in the body.Department of Dravyaguna
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32. Tikta, Kashaya Rasa,
Laghu, Ruksha Guna,
Ushna Veerya and
Katu Vipaka
are responsible for normalcy of Kapha.
Ushna Veerya dravyas are responsible for alleviation
of Vata.
Some drugs of Vedanasthapana are responsible for
Vedanahara action due to their Vedanasthapana
Prabhava. Department of Dravyaguna
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33. The drugs of Vedanasthapana mostly
contains, alkaloids, flavonoids, saponins,
quercetins etc. which are possibly
responsible for analgesic and anti-
inflammatory effect.
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34. Ashoka, Eranda, Guggulu, Kadamba,
Katphala, Nirgundi, , Rasna, Shaala,
Shatavari, Shirisha has been proved as
analgesic and anti-inflammatory agents by
experimental studies.
Most of the drugs mentioned for
Shoolahara or Vedanahara are Vatahara in
nature. Department of Dravyaguna
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35. . As per clinical study conducted in 40 patients of
osteoarthritis, the trial drugs were prepared in
the form of tablet 500 mg having equal
proportion of the drugs Sala(Shorea robusta
Gaertn.f), Kadamba (Anthocephalus indicus
A.Rich), Shirisha (Albizzia lebbeck Benth),
Ashoka(Saraca indica) and given in the dose of 1
gm thrice daily, showed significant relief in pain
without side effects
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36. 4.Conclusion
Vedanasthapana dravyas are also responsible for
establishment of well being feeling in the body
and not only act as analgesics or anti-
inflammatory agents.
Phytoconstituents like alkaloids, flavonoids,
saponins, quercitin etc. are responsible for
analgesic and anti-inflammatory effect
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37. 5.References
Charaka samhita
A Text Book of Dravyaguna Vigyan-Dr.Prash L Hegde &
Dr.Harini A
Shine P.A. et.al., Evaluation of Charakokta
Vedanasthapana Dashemani, Int. J. Ayu. Alt. Med.,
2017; 5(2): 56-612.
Jyotirupa S et al / Int. J. of Allied Med. Sci. and Clin.
Research Vol-5(1) 2017 [137-143]
Swapnil More. To study efficacy of drugs of
Vedanasthapana Gna ( Ghan Vati) in post-operative
pain management . Ayurlog: National journal of
Research in Ayurved Science.2014; 2(4): 1-11
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