Présentation faite au Xème congrés international sur le cross-linking du collagène cornéen (Zurich 5-6 décembre 2014).
Lecture given during the Xth international congress of corneal collagen cross-linking, (Zurich 5-6 th december 2014)
Higher fluence, irradiation profiles, epi on slideshareMichael Mrochen
cornea, cross linking, trans epithelium, riboflavin, high intensity, short treatment time, clinical results, Theo Seiler, Eberhard Spoerl, Arthur Cummings, Michael Mrochen
New method to treat capsular contractures of the Breast using a combination of capulotomy, capsulectomy with placement of calcium sulphate beads containing vancomycin and review of causes and treatments of capsular contracture with a critical review of the biofilm theory and how to utilize our knowledge of biofilms to prevent reformation of capsular contractures
Présentation proposée aux journées d'actualités thérapeutique de la SFEROV en octobre 2014. Intérêt de la Iontophorèse pour l'imprégnation de la cornée par la riboflavine avant cross-linking du collagène cornéen.
Marsupialization and Evacuation of Epiglottal Mucus Retention Cyst Using AcuP...Lumenis
Marsupialization and Evacuation of Epiglottal Mucus
Retention Cyst Using AcuPulse™ 40WG CO2 Laser System
with FiberLase™ Flexible CO2 Fiber
Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium
Classification of peri-implant diseases and condition, implant failures causes, Peri-implant mucositis and its management, Peri-implantitis and its classification, clinical features, Treatment (Surgical and Non-surgical) And management. Implant success rate and conclusion.
Ablation of Diffuse Keratosis and Resection of Thick Ulcerated Lesion on Late...Lumenis
Ablation of Diffuse Keratosis and Resection of Thick Ulcerated
Lesion on Lateral and Posterior Portion of Tongue Using
AcuPulse™ 40WG CO2 Laser System with FiberLase™ CO2 Fiber
Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium
SuperArgus PET/CT: Advanced Pre-Clinical Imaging for Small to Medium AnimalsInsideScientific
Positron Emission Tomography (PET) is the gold standard in metabolic imaging, providing high sensitivity to radiotracers used to detect metabolic activity or biomarkers in vivo. The most common uses for PET imaging in pre-clinical research include oncology, neurobiology, cardiology and dynamic imaging.
In this Scintica Instrumentation webinar, Tonya Coulthard discusses how Position Emission Tomography is used for preclinical imaging. Tonya provides an overview of applications including real-time imaging of awake animals, self-gated cardiac imaging and multiplexed PET imaging of standard and non-standard isotopes.
She also intruduces the SuperArgus PET/CT system, which is ideally suited for preclinical imaging of small animals like mice up to medium-sized animals like swine and non human primates.
Key Discussion Topics Include:
- Overview of Pre-Clinical PET/CT imaging
- Examples from applications including oncology, neurology, cardiology and dynamic imaging
- An introduction to SuperArgus PET/CT and what makes it unique
Higher fluence, irradiation profiles, epi on slideshareMichael Mrochen
cornea, cross linking, trans epithelium, riboflavin, high intensity, short treatment time, clinical results, Theo Seiler, Eberhard Spoerl, Arthur Cummings, Michael Mrochen
New method to treat capsular contractures of the Breast using a combination of capulotomy, capsulectomy with placement of calcium sulphate beads containing vancomycin and review of causes and treatments of capsular contracture with a critical review of the biofilm theory and how to utilize our knowledge of biofilms to prevent reformation of capsular contractures
Présentation proposée aux journées d'actualités thérapeutique de la SFEROV en octobre 2014. Intérêt de la Iontophorèse pour l'imprégnation de la cornée par la riboflavine avant cross-linking du collagène cornéen.
Marsupialization and Evacuation of Epiglottal Mucus Retention Cyst Using AcuP...Lumenis
Marsupialization and Evacuation of Epiglottal Mucus
Retention Cyst Using AcuPulse™ 40WG CO2 Laser System
with FiberLase™ Flexible CO2 Fiber
Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium
Classification of peri-implant diseases and condition, implant failures causes, Peri-implant mucositis and its management, Peri-implantitis and its classification, clinical features, Treatment (Surgical and Non-surgical) And management. Implant success rate and conclusion.
Ablation of Diffuse Keratosis and Resection of Thick Ulcerated Lesion on Late...Lumenis
Ablation of Diffuse Keratosis and Resection of Thick Ulcerated
Lesion on Lateral and Posterior Portion of Tongue Using
AcuPulse™ 40WG CO2 Laser System with FiberLase™ CO2 Fiber
Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium
SuperArgus PET/CT: Advanced Pre-Clinical Imaging for Small to Medium AnimalsInsideScientific
Positron Emission Tomography (PET) is the gold standard in metabolic imaging, providing high sensitivity to radiotracers used to detect metabolic activity or biomarkers in vivo. The most common uses for PET imaging in pre-clinical research include oncology, neurobiology, cardiology and dynamic imaging.
In this Scintica Instrumentation webinar, Tonya Coulthard discusses how Position Emission Tomography is used for preclinical imaging. Tonya provides an overview of applications including real-time imaging of awake animals, self-gated cardiac imaging and multiplexed PET imaging of standard and non-standard isotopes.
She also intruduces the SuperArgus PET/CT system, which is ideally suited for preclinical imaging of small animals like mice up to medium-sized animals like swine and non human primates.
Key Discussion Topics Include:
- Overview of Pre-Clinical PET/CT imaging
- Examples from applications including oncology, neurology, cardiology and dynamic imaging
- An introduction to SuperArgus PET/CT and what makes it unique
Introducing the SuperArgus PET/CT Systems; a Best In Class Imaging System wi...Scintica Instrumentation
These systems are ideally suited for pre-clinical imaging of small animals such as mice and rats, all the way up to medium sized animals such as rabbits, non-human primates and other similarly sized animals. Some of the unique imaging capabilities include real-time imaging of awake animals, as well as multiplexed PET imaging of standard and non-standard isotopes. Key research applications and example images will also be reviewed.
Positron Emission Tomography (PET) is the gold standard in metabolic imaging, providing high sensitivity to specific radiotracer used to detect specific metabolic activity or biomarkers in vivo. The most common uses for PET imaging in pre-clinical research include oncology, neurobiology, cardiology, as well as dynamic imaging.
These systems are considered to be best in class imaging system with state of the art detectors and electronics. The systems have been designed to be self-shielded, requiring no additional shielding at the location selected for installation. The systems come in a three different bore sizes allowing for imaging of animals such as mice all the way up to rabbits and even non-human primates. The CT component of these systems has been optimized for reduced radiation exposure, rapid acquisition times, and high resolution images; all ideal for the longitudinal studies so commonly performed in pre-clinical research.
The SuperArgus system is uniquely designed to provide consistent resolution across the entire field of view, while maintaining sensitivity and system performance. Reconstruction algorithms have also been implemented to rapidly process and display the acquired images. The system performs very well for standard imaging applications such as oncology, cardiology, etc. Additionally, the system has some unique features which allow for some unique imaging capabilities such as real-time awake animal imaging, self-gated cardiac imaging, as well as multiplex imaging of standard and non-standard isotopes.
Resonators based dielectric parameters change in Polyurethane as an exordial ...Hayagreev Keri
Carbowax-1000 a conducting polymer was found to give appreciable results in detection of explosive vapours in sensor applications. Coating of Carbowax-1000 over fused silica substrates using solvents such as Acetone, Chloroform, had less temperature stability. So, Carbowax-1000 is being used to form a Polyurethane. As a prelude dielectric parameters change was observed for HTPB-IPDI-PU (Hydroxyl-terminated polybutadiene – Isophorone diisocyanate – Polyurethane) when interacted with Toluene, THF, etc. using SPDR (Split Post Dielectric Resonator).
HTPB-IPDI-PU was synthesized and spin coated to obtain thin films of ≈2µm and cured for 5 days at 323 K. Initial frequency and quality factor value (Q) value were measured for bare substrate and polymer film coated substrate. Shift in resonance frequency and Q value was measured after placing Toluene, THF, etc. in µLs over the polymer film. Shift in resonance frequency ranged from 1-100 MHz for different solvents. Considerable Q value changes were also observed.
Ablation of Diffuse Vocal Cord Papillomatosis Using Digital AcuBlade™ Scannin...Lumenis
Ablation of Diffuse Vocal Cord Papillomatosis Using Digital AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible CO2 Laser Fiber in Patient with Major Retrognathia Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium
Ablation of Diffuse Vocal Cord Papillomatosis Using Digital AcuBlade™ Scannin...Lumenis
Ablation of Diffuse Vocal Cord Papillomatosis Using Digital
AcuBlade™ Scanning Micromanipulator and FiberLase™ Flexible
CO2 Laser Fiber in Patient with Major Retrognathia
Case by Marc Remacle, M.D. | CHU Mont-Godinne, University of Louvain, Belgium
This lecture reviews the role of laser therapy in dentistry in particular for Periodontal treatment. Dr. Smith reviews many of his own cases with the audience.
Please contact Dr. Smith with questions.
drsmith@cpident.com
Similar to Pack iontophoresis-cats famose-cxl_zurich_2014 (20)
Diaporama présenté lors des dernières journées SFEROV de Toulouse (26 octobre 2014). Utilisation de l'OCT dans le diagnostic des affections de la cornée chez le chien et le chat.
Newsletter n°1 de juin 2013. Actualités en ophtalmologie vétérinaire.
Les lentilles de collagène résorbables.
Cas clinique : cécité brutale chez un chat
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Phone Us ❤85270-49040❤ #ℂall #gIRLS In Surat By Surat @ℂall @Girls Hotel With...
Pack iontophoresis-cats famose-cxl_zurich_2014
1. EVALUATION OF PACK-CXL AFTER
IONTOPHORESIS
FOR THE TREATMENT OF MELTING KERATITIS
IN 10 CATS
Dr Frank Famose – Toulouse - France
Zürich – december 6th, 2014 Pierre Roy – Paris - France
9. Discussion : efficacy
Reduction of clinical
and pain score
Complete Epithelial
healing
Resolution of corneal melting
10.
11. Duration of treatment ?
Instillation
30 min
Iontophoresis
5 min
Irradiation
30 min
Accelerated CXL
3-10 min
Conventional protocol
Duration > 1 hour
Ionto + acc. CXL protocol
Duration < 20 min.
12. Conclusion: IONTOPHORESIS
Resolution of corneal melting
Results similar to
conventional instillation
No adverse reaction or pain
Reduction of
procedure duration
Good afternood Ladies and Gentlemen, before talking about iontophoresis and its application to corneal cross-linking, I’d like to thank the ECVO comitee for allowing me to present these results.
As you know, melting keratitis is a serious condition which is considered as an ocular emergency due to the high risk or corneal perforation. The melting of the cornea is due to metalloproteinase imbalance in relation with infectious or not infectious conditions. When the medical treatment, based on antibiotics and anticollagenases doesn’t succeed, surgery is indicated for tectonic purposes. Corneal collagen cross-linking is used for the treatment of infectious or melting keratitis in humans for some years and more recently for dogs, cats and horses.
The principle of iontophoresis is to increase the penetration of a ionized substance through a tissue by the application of a constant electric current. It has been used for first time in ophthalmology in the beginning of the 20th century. Many studies have been conducted since 1990 for the delivery of many drugs in the eye (like steroids and so on). The first use of iontophoresis for riboflavin delivery was published recently for the treatment of keratoconus. For the moment, no veterinary clinical use of ionto has been described and no data for keratitis treatment is available.
The aim of this study is to evaluate the clinical outcome after treatment of melting keratitis after iontophoresis of riboflavin and cross-linking in feline patients.
Inclusion criteria were represented by feline patients presenting with corneal melting with poor response to previous medical treatment
On day one, cats under general anesthesia have their cornea cleaned and sampled. Riboflavin impregnation by iontophoresis and an accelerated cross-linking.
Follow-up was conducted for one month with evaluation of pain and clinical score and measurement of ulceration and infiltration surface.
After treatment, we see a rapid reduction in pain and clinical score and disappearance of the ulcer and of the zone of infiltration.
You see that there is a positive clinical score à one month, this is due to
The aim of this study was to evaluate the efficacy of cross-linking after iontophoresis of riboflavin. We have observed the resolution of corneal melting with complete epithelial healing and reduction of clinical and pain scores in all cases.
… we see that all the criteria have a similar progression in both groups during the follow-up period.
If we consider the duration of treatment, we see that conventional protocol takes more than an hour to be completed. With iontophoresis and accelerated cross-linking the duration of treatment can fall under 20 minutes according to the intensity of UVA you’re using. This has the advantage to shorten the duration of anesthesia.
In a first step, we can conclude that iontophoresis of riboflavin followed by accelerated cross-linking was associated with a good outcome in the resolution of corneal melting in cats. That these results are similar to conventional instillation with a shorter treatment duration and no adverse reaction.
Thank you for your attention. I’ll be happy to answer to any question.