This document outlines an organic synthesis course that covers process analysis and evaluation. It discusses the history of organic synthesis, retrosynthetic analysis, linear and convergent synthesis approaches, and selectivity including chemoselectivity, regioselectivity, and stereoselectivity. The document also provides examples of synthesis processes and outlines the typical laboratory synthesis approach of running reactions, isolating products, purifying through column chromatography, obtaining NMR spectra, and more.

1. Organic
Synthesis
Course-0456: Process Analysis and Evaluation
Advisor: Chaniago Yus Donald
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Presented By

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5. Organic Synthesis
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7. History
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History

9. Retrosynthetic Analysis
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10. Practice of Synthesis
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11. Analysis
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12. Design and Execution of Synthesis
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13. Trouble Shooting
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14. Linear and Convergent Synthesis
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15. Examples
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16. Examples
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17. Synthesis of Chlorobenzide
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18. Synthesis of Fenfluoramine
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19. Selectivity in Organic Synthesis
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20. Chemoselectivity
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21. Examples
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22. Regioselectivity
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23. Examples
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24. Stereoselectivity
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RM RM RM RRR
Checking of Reaction Progress Through TLC Plates
https://www.youtube.com/watch?v=kx9Ilfqp8RE
Laboratory Synthesis Approach

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Running Solvent

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Isolation Of Desired Product

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Evaporation of solvent from Isolated Product through Column
Chromatography on Rota Evaporator

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Vacuum Drying of Isolated Product

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NMR Sample in NMR Tube

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NMR Spectrum for Isolated Product
1H-NMR
13C-NMR

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