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NUTRITION: SETTING 
THE LIMITS FOR WOUND 
HEALING 
ELIMINATING THE WEAKEST LINK 
Laura King APD, AEP
Agenda and Objectives 
 Increase awareness of the ability of 
compromised nutrition status to compromise 
wound healing 
 Increase knowledge of broad range of 
nutrients that can play a nutritional role in 
wound healing physiology 
 Increase knowledge of active ways that you 
can positively influence the wound care 
outcomes for your residents
Wound Severity 
 Stage 1 
 Stage 11 
 Stage 111 
 Stage 1V 
Increasing 
severity
Phases of Wound Healing- 4 R’s 
 Regeneration - Inflammatory phase 
 Repair- Proliferative phase 
 Revascularisation- Proliferative phase 
 Re-epithilialisation- Remodelling or maturation 
phase
Regeneration- Inflammatory phase 
 Day 1-6 
 Key nutrient involvement 
 Vitamin K and Calcium contribute to blood clotting 
 Arginine and Vitamin C regulates nitric oxide 
 Glutamine and carbohydrates are utilised with 
increased energy requirements 
 Glutamine is utilised as a DNA/ RNA precursor 
 Vitamin A stimulates immune response
Repair-Proliferative phase 
 Day 3 to Week 3 
 Key nutrient involvement 
 Arginine regulates fibroblast and macrophage 
contributions to the repair phase 
 Zinc, Vitamin A, Vitamin C and Iron stabilise, or 
contribute to the development of, collagen 
structure
Revascularisation-Proliferative phase 
 Day 3 to Week 3 
 Key nutrient involvement 
 Vitamin C contributes to capillary formation 
 Protein (amino acids) provides the building blocks 
for collagen synthesis 
 Protein (amino acids) are involve in making 
enzymes required for vascularisation 
 Inadequate protein and fatty acids lead to 
processes that interfere revascularisation
Re-epithilialisation- 
Remodelling or maturation phase 
 2 weeks to 2 years 
 Key nutrient involvement 
 Zinc is used for dozens of enzymes that 
contribute to epithelialisation 
 Vitamin C, Magnesium and Zinc contribute to 
ongoing stability of late stage wound
Nutrients involved in Wound Healing 
Carbohydrate 
Fat 
Protein 
Zinc 
Vitamin C 
Vitamin A 
Copper 
Arginine 
Glutamine 
Selenium 
This broad 
range of 
nutrients 
implicates 
any resident 
with low 
nutrition 
status
Good nutrition is a must! 
 The broad range of nutrients required means that 
residents who are: 
At risk of poor nutrition 
+ 
Have a wound 
= 
Recipe for poor healing
Nutrition Intervention 
So... What can be done?
1. Adequate protein and energy 
Well how do we measure this? 
 Unintended weight loss (>10% loss in 1-3/12) 
 Not receiving oral supplementation 
 Poor MMT score 
Nutrition screening, using a validated tool for the appropriate 
clinical setting, should be undertaken on all adults with pressure 
injuries to identify those at risk of poor healing due to nutritional 
problems. 
NHMRC Grade of recommendation: B 
Onward referral to Dietitian as indicated
2. Nutrient Supplementation 
 Zinc 
 Vitamin C 
 Vitamin A 
 Copper 
*Supplementation is valuable ONLY when serum 
levels are low* 
NOTE: Supplementation of zinc or copper in normal 
serum is detrimental- it impacts on zinc/copper and 
iron metabolism- a delicate balance
3. Arginine supplementation 
 A conditionally essential amino acid 
 If deficient, may be the weakest link to 
effective wound healing 
 In chronic wounds > stage 2; the benefit from 
arginine supplementation will be seen in 2-3 
weeks if going to be effective
Okay, so can be done? 
 Assess risk in regards to nutrient 
intake- identify weight change, loss 
of appetite and refer as necessary 
 Dietitian assessment and request of personalised 
measures to optimise oral protein and energy 
intake 
 Dietitian assessment may indicate opportunity to 
optimise serum levels- LMO request for serum 
 Replacement of inadequate nutrients as indicated 
by serum results 
 Dietitian may consider Arginine supplementation 
in specific cases
Okay, so can be done? 
 Assess risk in regards to nutrient intake- identify 
weight change, loss of appetite and refer as 
necessary 
 Dietitian assessment and request of 
personalised measures to optimise 
oral protein and energy intake 
 Dietitian assessment may indicate opportunity to 
optimise serum levels- LMO request for serum 
 Replacement of inadequate nutrients as indicated 
by serum results 
 Dietitian may consider Arginine supplementation 
in specific cases
Okay, so can be done? 
 Assess risk in regards to nutrient intake- identify 
weight change, loss of appetite and refer as 
necessary 
 Dietitian assessment and request of personalised 
measures to optimise oral protein and energy 
intake 
 Dietitian assessment may indicate 
opportunity to optimise serum levels- 
LMO request for serum 
 Replacement of inadequate nutrients as indicated 
by serum results 
 Dietitian may consider Arginine supplementation 
in specific cases
Okay, so can be done? 
 Assess risk in regards to nutrient intake- identify 
weight change, loss of appetite and refer as 
necessary 
 Dietitian assessment and request of personalised 
measures to optimise oral protein and energy 
intake 
 Dietitian assessment may indicate opportunity to 
optimise serum levels- LMO request for serum 
 Replacement of inadequate nutrients 
as indicated by serum results 
 Dietitian may consider Arginine supplementation 
in specific cases
Okay, so can be done? 
 Assess risk in regards to nutrient intake- identify 
weight change, loss of appetite and refer as 
necessary 
 Dietitian assessment and request of personalised 
measures to optimise oral protein and energy 
intake 
 Dietitian assessment may indicate opportunity to 
optimise serum levels- LMO request for serum 
 Replacement of inadequate nutrients as indicated 
by serum results 
 Dietitian may consider Arginine 
supplementation in specific cases
Assessable component 
 Okay! So now that you have learnt about how 
nutrition can optimise wound healing- put 
yourself to the test...
Assessable component 
1. With regards to nutritional wound care 
management, nursing staff in residential aged 
care are responsible for: 
a. Commencing oral supplementation and referral to 
Dietitian as indicated 
b. Ordering blood tests and prescribing nutrient 
supplementation 
c. Nutrition screening, communication and 
documentation, actioning referrals, ensuring 
compliance with supplementation 
d. All of the above 
e. A and C
Assessable component 
2. In your own words describe why poor nutrition 
can be considered the weakest link in 
effective wound healing.
Assessable component 
3. True or false: 
Poor nutrition is always the cause of poor 
wound healing. 
(If false, provide brief list of other factors that 
may need consideration)
Assessable component 
Email your answers, along with any additional 
queries or questions, to: 
laura.hosking@greatideas.net.au 
I look forward to providing you with feedback, 
and further information as needed. 
Thank you for completing this CPD activity!
NUTRITION: SETTING 
THE LIMITS FOR WOUND 
HEALING 
ELIMINATING THE WEAKEST LINK 
Laura King APD, AEP
Nutrition and wound healing

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Nutrition and wound healing

  • 1. NUTRITION: SETTING THE LIMITS FOR WOUND HEALING ELIMINATING THE WEAKEST LINK Laura King APD, AEP
  • 2. Agenda and Objectives  Increase awareness of the ability of compromised nutrition status to compromise wound healing  Increase knowledge of broad range of nutrients that can play a nutritional role in wound healing physiology  Increase knowledge of active ways that you can positively influence the wound care outcomes for your residents
  • 3. Wound Severity  Stage 1  Stage 11  Stage 111  Stage 1V Increasing severity
  • 4. Phases of Wound Healing- 4 R’s  Regeneration - Inflammatory phase  Repair- Proliferative phase  Revascularisation- Proliferative phase  Re-epithilialisation- Remodelling or maturation phase
  • 5. Regeneration- Inflammatory phase  Day 1-6  Key nutrient involvement  Vitamin K and Calcium contribute to blood clotting  Arginine and Vitamin C regulates nitric oxide  Glutamine and carbohydrates are utilised with increased energy requirements  Glutamine is utilised as a DNA/ RNA precursor  Vitamin A stimulates immune response
  • 6. Repair-Proliferative phase  Day 3 to Week 3  Key nutrient involvement  Arginine regulates fibroblast and macrophage contributions to the repair phase  Zinc, Vitamin A, Vitamin C and Iron stabilise, or contribute to the development of, collagen structure
  • 7. Revascularisation-Proliferative phase  Day 3 to Week 3  Key nutrient involvement  Vitamin C contributes to capillary formation  Protein (amino acids) provides the building blocks for collagen synthesis  Protein (amino acids) are involve in making enzymes required for vascularisation  Inadequate protein and fatty acids lead to processes that interfere revascularisation
  • 8. Re-epithilialisation- Remodelling or maturation phase  2 weeks to 2 years  Key nutrient involvement  Zinc is used for dozens of enzymes that contribute to epithelialisation  Vitamin C, Magnesium and Zinc contribute to ongoing stability of late stage wound
  • 9. Nutrients involved in Wound Healing Carbohydrate Fat Protein Zinc Vitamin C Vitamin A Copper Arginine Glutamine Selenium This broad range of nutrients implicates any resident with low nutrition status
  • 10. Good nutrition is a must!  The broad range of nutrients required means that residents who are: At risk of poor nutrition + Have a wound = Recipe for poor healing
  • 11. Nutrition Intervention So... What can be done?
  • 12. 1. Adequate protein and energy Well how do we measure this?  Unintended weight loss (>10% loss in 1-3/12)  Not receiving oral supplementation  Poor MMT score Nutrition screening, using a validated tool for the appropriate clinical setting, should be undertaken on all adults with pressure injuries to identify those at risk of poor healing due to nutritional problems. NHMRC Grade of recommendation: B Onward referral to Dietitian as indicated
  • 13. 2. Nutrient Supplementation  Zinc  Vitamin C  Vitamin A  Copper *Supplementation is valuable ONLY when serum levels are low* NOTE: Supplementation of zinc or copper in normal serum is detrimental- it impacts on zinc/copper and iron metabolism- a delicate balance
  • 14. 3. Arginine supplementation  A conditionally essential amino acid  If deficient, may be the weakest link to effective wound healing  In chronic wounds > stage 2; the benefit from arginine supplementation will be seen in 2-3 weeks if going to be effective
  • 15. Okay, so can be done?  Assess risk in regards to nutrient intake- identify weight change, loss of appetite and refer as necessary  Dietitian assessment and request of personalised measures to optimise oral protein and energy intake  Dietitian assessment may indicate opportunity to optimise serum levels- LMO request for serum  Replacement of inadequate nutrients as indicated by serum results  Dietitian may consider Arginine supplementation in specific cases
  • 16. Okay, so can be done?  Assess risk in regards to nutrient intake- identify weight change, loss of appetite and refer as necessary  Dietitian assessment and request of personalised measures to optimise oral protein and energy intake  Dietitian assessment may indicate opportunity to optimise serum levels- LMO request for serum  Replacement of inadequate nutrients as indicated by serum results  Dietitian may consider Arginine supplementation in specific cases
  • 17. Okay, so can be done?  Assess risk in regards to nutrient intake- identify weight change, loss of appetite and refer as necessary  Dietitian assessment and request of personalised measures to optimise oral protein and energy intake  Dietitian assessment may indicate opportunity to optimise serum levels- LMO request for serum  Replacement of inadequate nutrients as indicated by serum results  Dietitian may consider Arginine supplementation in specific cases
  • 18. Okay, so can be done?  Assess risk in regards to nutrient intake- identify weight change, loss of appetite and refer as necessary  Dietitian assessment and request of personalised measures to optimise oral protein and energy intake  Dietitian assessment may indicate opportunity to optimise serum levels- LMO request for serum  Replacement of inadequate nutrients as indicated by serum results  Dietitian may consider Arginine supplementation in specific cases
  • 19. Okay, so can be done?  Assess risk in regards to nutrient intake- identify weight change, loss of appetite and refer as necessary  Dietitian assessment and request of personalised measures to optimise oral protein and energy intake  Dietitian assessment may indicate opportunity to optimise serum levels- LMO request for serum  Replacement of inadequate nutrients as indicated by serum results  Dietitian may consider Arginine supplementation in specific cases
  • 20. Assessable component  Okay! So now that you have learnt about how nutrition can optimise wound healing- put yourself to the test...
  • 21. Assessable component 1. With regards to nutritional wound care management, nursing staff in residential aged care are responsible for: a. Commencing oral supplementation and referral to Dietitian as indicated b. Ordering blood tests and prescribing nutrient supplementation c. Nutrition screening, communication and documentation, actioning referrals, ensuring compliance with supplementation d. All of the above e. A and C
  • 22. Assessable component 2. In your own words describe why poor nutrition can be considered the weakest link in effective wound healing.
  • 23. Assessable component 3. True or false: Poor nutrition is always the cause of poor wound healing. (If false, provide brief list of other factors that may need consideration)
  • 24. Assessable component Email your answers, along with any additional queries or questions, to: laura.hosking@greatideas.net.au I look forward to providing you with feedback, and further information as needed. Thank you for completing this CPD activity!
  • 25. NUTRITION: SETTING THE LIMITS FOR WOUND HEALING ELIMINATING THE WEAKEST LINK Laura King APD, AEP

Editor's Notes

  1. Inital response
  2. Building stage
  3. ? So we have had a brief overview on the role of nutrients in wound healing- what intervention can assist with improved outcomes