This document summarizes research comparing selective laser trabeculoplasty (SLT) and argon laser trabeculoplasty (ALT) for treating glaucoma. SLT uses lower energy "cold laser" technology, resulting in less thermal damage to trabecular meshwork cells and architecture compared to ALT. Precise targeting is not required for SLT. SLT typically does not cause endothelial membrane formation, crater formation, coagulative damage, or disruption of trabecular beams and endothelial cells like ALT can. Clinical studies have found similar IOP decreases of around 20% for both SLT and ALT. The document also briefly describes new laser and endoscopic cyclophotocoagulation procedures for glaucoma treatment.

2. DESENZANO 11 Novembre 2016

5. LASER & TECNOLOGIA

6. FOTOCOAGULAZIONE
DESTRUENTE

9. 9

10. 10

11. Laser Trabeculoplasty for Glaucoma
ALT vs SLT, Animation
1.

12. SLT Clinical Footage Treatment
Protocol

13. 13

14. • SLT incorporates "cold laser" technology Which Results less thermal damage to the
trabecular meshwork architecture than that caused by the argon laser.
• SLT achieves isolated destruction of the pigmented trabecular meshwork cells.
There is minimal or no thermal or collateral damage to the surrounding non-
pigmented cells because the energy output during SLT is 100 times less than that
of ALT, and the pulse duration is much shorter.
• Precise Targeting Not Required for SLT.
• Endothelial membrane formation on the trabecular meshwork, usually found in
eyes treated with ALT, is not typically observed after SLT.
• ALT produces crater formation, coagulative damage, fibrin deposition and
disruption of trabecular beams and endothelial cells.

15. Author/Year Eyes IOP Decrease
Damji,1999 18 ALT
18 SLT
22%
21%
Popiela,2000 27 ALT
27 SLT
13.0%
13.4%
Martinez-de-la-
casa,2004
20 ALT
20 SLT
19.5%
22.2%

18. New Laser Glaucoma Treatment Cyclo G6
Replacing Traditional Surgery
2.

19. IRIDEX CYCLO G 6

20. ECP laser for glaucoma during
cataract surgery

21. Endoscopic Cyclophotocoagulation
(ECP) Curved Endoscopes
3.

22. Endoscopic Cyclophotocoagulation
(ECP) Open Angle Glaucoma

23. The IOPtimate a CO2 Laser Assisted
System for surgically treating glaucoma
5.

27. 2D Biometrics (CCD,IR, Laser, Scanner) 1D Biometrics