The document summarizes new features and functionalities of the updated STN platform. Key points include: - An updated structure editor with improved drawing tools and the ability to set Markush attributes via right-click. - The ability to search across multiple databases (BIOSIS, Embase, MEDLINE) for substances in the CAS Registry using new cross-file search operators. - Export search results to XML and BizInt Smart Charts formats for further analysis and reporting. - Expanded content including new life sciences databases, engineering/technology databases, and Elsevier's ReaxysFile databases. - Integration of the Derwent Markush Resource (DWPIM) for the