This document describes a biotech startup's transition from using various disconnected systems like Excel, PowerPoint and paper notebooks, to using the Dotmatics informatics platform. The startup implemented Dotmatics for compound registration and searching, data analysis to reduce time spent from afternoons to 30 minutes, and electronic notebooks for chemistry to enable searching and collaboration. Dotmatics provided the startup with a single vendor solution that integrated all of their informatics needs, was easy to deploy across platforms, and enabled collaboration with researchers in China.