This document discusses neutrophilia, which is an increased number of neutrophils in the blood. Neutrophils are a type of white blood cell that helps fight infections. Neutrophilia can be caused by infections, inflammation, smoking, stress, and other factors. Symptoms may include bleeding, low body temperature, and respiratory issues. The absolute neutrophil count is used to define neutrophilia as greater than 8,000 cells per cubic mm. Treatment involves identifying the underlying cause, bone marrow testing, medication changes, and lifestyle modifications to support the immune system.

1. Regents Biology 2015/2016
Mohamed M.Elsaied
2016/2017
[ Neutrophilia ]

2.  Introduction
Mohamed M.Elsaied
2016/2017
 White blood cell
 One of the cells the body makes to help fight infections .
There are several types of white blood cells
I. Granulocytes
1- Neutrophils
2-Eosinophils
3-Basophils
II. Non granular
4 -Monocytes
5-Lymphocytes

3. Mohamed M.Elsaied
2016/2017

4.  Definition of Neutrophilia
Mohamed M.Elsaied
2016/2017
 Neutrophilia is a medical condition that involves the increase of
neutrophil in the blood or serum.
 This is considered as the most common form of leukocytosis
The neutrophils are responsible in killing or assistance of
fighting off the foreign materials found in the body such as
(bacteria and fungi).
 Its precursors > 7,000/cmm

5.  Neutrophilia Causes
Mohamed M.Elsaied
2016/2017
The causes of neutrophilia are the following:-
1. Acute infection
2. Inflammation
3. Hemorrhage
4. Sepsis
5. Cigarette smoking
6. Stress
7. Metabolic processes
8. Drugs
9. Malignancy
10. labor

6. Mohamed M.Elsaied
2016/2017
 Causes of Neutrophilia (cont.)
1. Chronic granulocytic leukaemia
2. Other myeloproliferative disorders
Diagnosis :-
1. Low LAP score .
2. Philadelphia chromosome .

7.  Neutrophilia Symptoms
Mohamed M.Elsaied
2016/2017
I. Bleeding leading to hypotension, tachycardia and most probably
sepsis.
II. Hypothermia or decreased body temperature.
III. Tachypnea and dyspnea would most likely happen. These are
respiratory-related symptoms.
IV. Rashes
V. Wound that doesn’t heal quickely
VI. Abscesses

8.  Neutrophilia count
Mohamed M.Elsaied
2016/2017
Neutrophilia is defined as an increase in circulating neutrophils
in the peripheral blood.
 The absolute neutrophil count (ANC) defines neutrophilia. ANC
is found by multiplying the percentage of bands and neutrophils
on a differential by the total white blood cell count. An abnormal
ANC is more than 8,000 cells per cubic mm.

9. Mohamed M.Elsaied
2016/2017
I. Referral to a hematologist
II. Bone marrow aspiration. This shall identify presence of
hematological problem. Bone marrow depression may be
present that is why testing the sample from the bone marrow
aspiration is necessary.
III. Close supervision of the blood results are indeed necessary
in order to check progress of the condition. This is needed to
be monitored so that success of the treatment course can be
attained.
 Tips and remedies for neutrophilia

10. Mohamed M.Elsaied
2016/2017
IV. Discuss with the doctor the need of taking drugs that could
cause neutrophilia. Asking for alternative medications from
such should be helpful in preventing the disease process.
V. Maintain a healthy lifestyle so that one can avoid acquiring
acute infections that are highly causative of neutrophilia.
Having yearly influenza shots can also avoid acquiring viral
infections. Reduce or slowly stop bad habits that can alter
one’s natural defenses of the body is a preventive measure for
neutrophilia.

11.  Reference
Mohamed M.Elsaied
2016/2017
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