Lecture 5 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University. Includes epidemiology, pharmacokinetics, pharmacodynamics, and overdose.
Lecture 4 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University. Includes hypericum, melatonin, ginsing, serotonin
lecture 5 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College. A crash course in statistics including descriptives and inferential stats.
Research Methods: Multifactorial DesignBrian Piper
lecture 10 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College
Research Methods: Experimental Design I (Single Factor)Brian Piper
lecture 9 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College,
Research Methods: Ethics I (Human Research)Brian Piper
lecture 2 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College,
Lecture from week 5 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University.
Research Methods: Observational ResearchBrian Piper
lecture 14 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College on observational research design
Lecture 4 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University. Includes hypericum, melatonin, ginsing, serotonin
lecture 5 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College. A crash course in statistics including descriptives and inferential stats.
Research Methods: Multifactorial DesignBrian Piper
lecture 10 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College
Research Methods: Experimental Design I (Single Factor)Brian Piper
lecture 9 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College,
Research Methods: Ethics I (Human Research)Brian Piper
lecture 2 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College,
Lecture from week 5 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University.
Research Methods: Observational ResearchBrian Piper
lecture 14 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College on observational research design
Introductory Psychology: Social PsychologyBrian Piper
lecture 30 from a college level introduction to psychology course taught Fall 2011 by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University, includes Stanley Milgram, Zimbardo's prison studies
Lecture 1 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University. Covers writing a research paper, routes of administration, writing a research paper, animal research ethics, neurochemistry.
Research Methods: Ethics II (Animal Research)Brian Piper
lecture 3 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College, includes IACUC, animal welfare act, refinement, reduction, replacement
Lecture 21 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University. Focus is on DSM IV TR criteria for anxiety disorders and their pharmacological treatments.
Lecture 7 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University.
Current recreational drugs: RX462 Drug Abuse & Society, Spring 2015 Class pre...Brian Piper
These are the presentations from 2nd and 3rd year pharmacy students from semester long projects on a recreational drug of their choosing. Each presentations contains what was currently known (as of spring, 2015) about the history, epidemiology, pharmacokinetics, and pharmacodynamics of a recreational drug of their choosing.
Lecture 13 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College.
This is a presentation that was given at the Lost in Translation 2013: Exploring the Origins of Addiction conference that took place on March 25 - 26, 2013 in Vancouver, British Columbia, Canada
A presentation given at the 2016 Traffic Safety Conference during Breakout Session 14: Drugs and Driving. By Robert D. Johnson, Ph.D., F-ABT, Chief Toxicologist, Tarrant County Medical Examiner’s Office
Introductory Psychology: Social PsychologyBrian Piper
lecture 30 from a college level introduction to psychology course taught Fall 2011 by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University, includes Stanley Milgram, Zimbardo's prison studies
Lecture 1 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University. Covers writing a research paper, routes of administration, writing a research paper, animal research ethics, neurochemistry.
Research Methods: Ethics II (Animal Research)Brian Piper
lecture 3 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College, includes IACUC, animal welfare act, refinement, reduction, replacement
Lecture 21 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University. Focus is on DSM IV TR criteria for anxiety disorders and their pharmacological treatments.
Lecture 7 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University.
Current recreational drugs: RX462 Drug Abuse & Society, Spring 2015 Class pre...Brian Piper
These are the presentations from 2nd and 3rd year pharmacy students from semester long projects on a recreational drug of their choosing. Each presentations contains what was currently known (as of spring, 2015) about the history, epidemiology, pharmacokinetics, and pharmacodynamics of a recreational drug of their choosing.
Lecture 13 from a college level research methods in psychology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Linfield College.
This is a presentation that was given at the Lost in Translation 2013: Exploring the Origins of Addiction conference that took place on March 25 - 26, 2013 in Vancouver, British Columbia, Canada
A presentation given at the 2016 Traffic Safety Conference during Breakout Session 14: Drugs and Driving. By Robert D. Johnson, Ph.D., F-ABT, Chief Toxicologist, Tarrant County Medical Examiner’s Office
objectives are understanding the scop of substance abuse in the elderly and realize the future implications of substance abuse in the baby bommer cohorot and understanding the definition of alcohol dependance and how to recognize them and much more
welcome to :
http://www.ethanolabuse.com
Lecture 18 from a college level neuropharmacology course taught in the spring 2012 semester by Brian J. Piper, Ph.D. (psy391@gmail.com) at Willamette University. Focus is on the pharmacokinetics, pharmadynamics, and epidemiology.
Drug Abuse & Society (RX 462) Presentations-Spring 2014Brian Piper
This includes end of the semester presentations made by 2nd and 3rd year pharmacy students as part of an elective course. Each student was asked to provide information about history, epidemiology, pharmacodynamics, pharmacokinetics, and toxicology. Older "classic" (psilocybin, ayahuasca, crack), newer (JWB-018, mephedrone, MDA) drugs were covered as well as agents that have appreciable use outside the U.S. (desomorphine, areca nut, kava).
Overview of electronic cigarettes including history, components, safety and adverse events, efficacy in smoking cessation, pharmacokinetics and epidemiology. This presentation was originally delivered to 2nd year pharmacy students as part of a two semester class on pharmacology and toxicology.
Examination of Sexually Dimorphic Behavior on the Novel-Image Novel-Location ...Brian Piper
Objectives: Sex differences in object location memory favoring females appear to be a replicable phenomenon but may also depend on the task demands. This investigation evaluated if females outperformed males at both a short (immediate) and long (half-hour) interval between the learn and test condition using a recently developed version of the Novel-Image Novel-Location (NINL) test (Piper et al. 2011, Physiology & Behavior,
103, 513 - 522). Methods: Young-adults (N = 184) completed a standardized handedness inventory and the NINL. Results: Participants assigned to the Immediate and Delayed conditions did not differ in age, sex, or handedness. The NINL total score was higher among females at the Immediate, but not Delayed, interval. However, within the Delayed condition, females excelled at correctly identifying the unchanged items with a similar pattern for the Novel-Location (NL) scale. Conclusions: These findings are consistent with the view that sexually dimorphic performance favoring females in neurocognitive function can also extend to tasks that have a spatial component.
Drug abuse and society drug presentations: Spring 2013Brian Piper
This presentation is on recreational drugs as part of a elective course for 2nd and 3rd year pharmacy students. The instructions were to include what is known about history, pharmacodynamics, pharmacokinetics including common routes of administration, overdose potential, and recent epidemiology.
The class chose some older agents (peyote, LSD, mushrooms, cocaine), others that have only become more popular recently (bath sats, synthetic cannabinoids), and some medical drugs (methylphenidate, oxycontin).
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
5. 3.7 Getting out
• Alcohol dehydrogenase (AlcDH):
• Aldehyde dehydrogenase (AldDH)
AlcDH AldDH
• Ethanol --------> Acetaldehyde ------> Acetic Acid
CH3-CH2-OH CH3-CH=O CH3-C-OH
||
O
AlcDH: lower levels in stomach of women
AldDH: half of Asians have a dysfunctional version; this
results in flushing and nausea, Antabuse inhibits
See also: http://endeavor.med.nyu.edu/~strone01/doctor.html
6. 2.7
Sex Differences
• Lower level of AlcDH in stomach of
females
• Fat content
• Sex hormones
• Tolerance
9. Physiological Blood Alcohol
Concentration Symptom
5.1
Effects Low (O.01%*) relaxation
• Dose dependent: Decreased
alertness
– low dose-stimulant
Loss of coordination/
– high dose-depressant reaction time
Difficulty standing/
walking
Slurred speech
Unable to walk
Table From Inaba, D.S. (2007).
unaided
*Mass/Volume Difficulty rousing
mg/dL
Coma
High (0.50) Death
10. 2004 Fatalities in Motor Vehicle Traffic Crashes
by Driver BAC – Massachusetts
2.9
.01-.07
BAC .08-.09 BAC 11.0%
4.7%
.10-.14 BAC
26.4%
Zero BAC .08+ BAC
61.1% 34.5%
.15+ BAC
62.6%
The average BAC among drunk drivers
involved in fatal crashes was 0.17 (2004).
Source: National Highway Traffic Safety Administration, U.S. Department of Transportation, 2005. Fatalities in motor
vehicle traffic crashes by the highest driver BAC in the crash, 2004 Fatal Analysis Reporting System (FARS).
11. Preventable
deaths.
Alcohol related fatality = one member of accident (driver, nonoccupant) has detectable
Alcohol (0.01 g/dl +) ,
There were 43,295 traffic fatalities (39% alcohol related).
http://www-nrd.nhtsa.dot.gov/pdf/nrd-30/NCSA/TSF2005/810616.pdftp://
.nhtsa.dot.gov/pdf/nrd-30/NCSA/TSF2005/810616.pdf
12. Chronic EtOH & Neurophsyiology
3.3
Find X among other letters,
“Oddball” task
Chorlian, D.B. (1995). Alcohol Health & Research World 19(4):315–320.
13. Chronic EtOH & Neuroanatomy
2.6
Rosenbloom, M., et al. (2003). Alcohol Research & Health 27(2):146–152.
14. 1.5
Teratology: High dose
Warren, Kenneth (2011). Perspectives on Fetal Alcohol Syndrome and Fetal Alcohol Spectrum Disorders. Available at: http://videocast.nih.gov/launch.asp?16613
15. Low-Dose?
• Women in Capetown, South Africa were interviewed after giving birth and their
offspring were grouped as:
– Unexposed Control (N=29): no EtOH
– Fetal Alcohol Syndrome (N=12): 4.2 drinks/day
– Partial FAS (N=18): 2.8 drinks/day
http://www.nlm.nih.gov/medlineplus/ency/images/ency/fu
– Heavy Exposed (N=34): 1.6 drinks/day
– Microencephalic (N=4): ?
• Children were tested at age 5
for classical conditioning:
Jacobson, S.W., et al. (2008). Alcohol: Clin Exp Res 37, 2, 365-372.
17. Monitoring the Future
• National survey, conducted annually by NIDA of
secondary school (8th, 10th, or 12th), college
students, and adults (<45 yrs)
• Missing data (drop-outs = 15%, not attending) =
under-estimation
• Concern about labels (inadvertent marketing)
• Self-report
– Knowledge (e.g. steroids, diet pills, club drugs)
– Memory (e.g. How many drinks?)
– Taboo
http://www.monitoringthefuture.org/
18. Demographics
• Compares use by:
– Year (1975 – present)
– Sex
– Ethnicity
– Parental education
?
– Region
– College plans
19.
20. Frequency of Alcohol Use
• Monitoring
the Future
• Nationally
representative
• 15,000+
21. Frequency of Alcohol Use
• Monitoring
the Future
• Nationally
representative
• 15,000+
27. 3.5 Alcoholics Anonymous
• Founded by Bill Wilson & Bob Smith in 1935
• Medical-Spiritual Approach based on:
– Alcoholism is a progressive disease.
– Alcoholics must give themselves to a higher power.
– Total abstinence
• Effectiveness ?
28. Public Health
Premature Safety in Brain Interpersonal Traffic cirrhosis Heart Cost
Deaths overdose Damage Violence Accidents Damage to society
(UK) (Billion
Per year
Pounds)
10,000 +/year
ethanol 22,000 1500
10 x Yes ++ ++ 18.5
Pleasure
dose
ecstasy 0.01
10 15 x ? 0 0 0 0
Nutt, D.J. (2006) J. Psychopharmacology, 20, 315-317.
29. Summary
• Pharmacokinetics: enzymes
• Pharmacodynamics: neurotransmitters
• Teratology: consequences
– Randall: http://videocast.nih.gov/launch.asp?10420
• Epidemiology: Who uses? What are risk
factors?
Total Length = 57.4 minutes