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Biological explanations of
aggression

Neural and hormonal mechanisms and
aggression
1
Essentially the argument is
• Low levels of serotonin
• High levels of dopamine
• High levels of testosterone
• Low levels of cortisol
..... are associated with aggression
2
Serotonin AO1
• Thought to inhibit aggressive responses to
emotional stimuli
• Low levels associated with increased
susceptibility to impulsive behaviour,
aggression & violent suicide
• Drugs which reduced serotonin increased
measures of hostility and aggression in males
(but not females)
3
Dopamine AO1
• Link less well established than serotonin
• Giving amphetamines (which increase
dopamine) increases aggressive behaviour
• Giving anti-psychotics (which reduce
dopamine) reduced aggressive behaviour in
violent delinquents

4
Testosterone AO1
• Thought to act on areas of brain which control
aggression from young adulthood onwards
• Thought to be primary biochemical influence on
aggression
• Salivary testosterone levels were able to
differentiate between violent and non-violent
criminals and their crimes
• Aggressive behaviour in drunken males also
positively correlated with testosterone levels
• Castrated male mice showed decreased
aggression which then increased when given
testosterone again
5
Cortisol AO1
• Cortisol mediates other hormones such as
testosterone
• High levels of cortisol inhibit testosterone and so
inhibit aggression
• So low levels of cortisol associated with increased
aggression and studies have supported this.
• Low levels of cortisol have been found in
habitual violent offenders and also in violent
schoolchildren
6
AO2 Serotonin
• Findings on serotonin replicated in vervet
monkeys (Raleigh et al (1991)) But issue of:
– extrapolation

• Meta-analysis (Scerbo 1993) supports low level of
serotonin consistently found in aggressive
children and adults but found no dopamine
abnormalities
• Bond – drugs (anti-depressants) that increase
serotonin levels to reduce impulsive aggressive
behaviour.
7
AO2 Serotonin
• Findings on serotonin also confirmed via
studies on anti-depressants
• However Lenard (2008) cautions that
serotonin not just linked to aggression: also to
impulsive behaviour, depression, over-eating,
alcohol abuse; violent suicide

8
AO2 Dopamine
• Causal role of dopamine unclear
• Perhaps high levels of dopamine are an effect
rather than a cause because dopamine is
released by performing aggressive acts, so
aggression could be being rewarded in the
brain.

9
AO2 Testosterone
• Evidence conflicting on role of testosterone
• Studies showing positive correlation small
samples and self-report measures
• Studies mainly correlational (eg. Wagner) so
not possible to conclude that testosterone
causes aggression
• Also testosterone not always associated with
negative characteristics: improved sporting
and spatial abilities also been found
10
AO2 issues and debates
• Gender bias evident as most research done on
males (animals and humans) whereas it is
known that there are differences between the
genders in androgens
• Also cultural bias as most research conducted
in western countries

11
AO2 debates
• Reductionist to just consider role of
biochemistry alone
• Also need to consider genetic factors and
brain structure
• Eg. Phineas Gage suffered brain injury and
showed heightened levels of aggression
• Also need to consider the contribution of
environmental factors such as situational cues,
temperature, noise, overcrowding, and the
role of learning
12
AO2 application
• Clearly a very important & useful area of
biopsychological research and theory as aggression
associated with many anti-social phenomena in society,
eg. numerous forms of crime, violence
• If the role of biochemistry can be understood it can
perhaps be treated or managed
• Although there would be ethical issues associated with
giving people drugs simply to alleviate aggression (ie.
for social control) , or male castration, even if it may be
in the interests of multiple parties
• Could perhaps be treated more ethically through diet
(tryptophan) and exercise
13

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Neural explanations of aggression a2

  • 1. Biological explanations of aggression Neural and hormonal mechanisms and aggression 1
  • 2. Essentially the argument is • Low levels of serotonin • High levels of dopamine • High levels of testosterone • Low levels of cortisol ..... are associated with aggression 2
  • 3. Serotonin AO1 • Thought to inhibit aggressive responses to emotional stimuli • Low levels associated with increased susceptibility to impulsive behaviour, aggression & violent suicide • Drugs which reduced serotonin increased measures of hostility and aggression in males (but not females) 3
  • 4. Dopamine AO1 • Link less well established than serotonin • Giving amphetamines (which increase dopamine) increases aggressive behaviour • Giving anti-psychotics (which reduce dopamine) reduced aggressive behaviour in violent delinquents 4
  • 5. Testosterone AO1 • Thought to act on areas of brain which control aggression from young adulthood onwards • Thought to be primary biochemical influence on aggression • Salivary testosterone levels were able to differentiate between violent and non-violent criminals and their crimes • Aggressive behaviour in drunken males also positively correlated with testosterone levels • Castrated male mice showed decreased aggression which then increased when given testosterone again 5
  • 6. Cortisol AO1 • Cortisol mediates other hormones such as testosterone • High levels of cortisol inhibit testosterone and so inhibit aggression • So low levels of cortisol associated with increased aggression and studies have supported this. • Low levels of cortisol have been found in habitual violent offenders and also in violent schoolchildren 6
  • 7. AO2 Serotonin • Findings on serotonin replicated in vervet monkeys (Raleigh et al (1991)) But issue of: – extrapolation • Meta-analysis (Scerbo 1993) supports low level of serotonin consistently found in aggressive children and adults but found no dopamine abnormalities • Bond – drugs (anti-depressants) that increase serotonin levels to reduce impulsive aggressive behaviour. 7
  • 8. AO2 Serotonin • Findings on serotonin also confirmed via studies on anti-depressants • However Lenard (2008) cautions that serotonin not just linked to aggression: also to impulsive behaviour, depression, over-eating, alcohol abuse; violent suicide 8
  • 9. AO2 Dopamine • Causal role of dopamine unclear • Perhaps high levels of dopamine are an effect rather than a cause because dopamine is released by performing aggressive acts, so aggression could be being rewarded in the brain. 9
  • 10. AO2 Testosterone • Evidence conflicting on role of testosterone • Studies showing positive correlation small samples and self-report measures • Studies mainly correlational (eg. Wagner) so not possible to conclude that testosterone causes aggression • Also testosterone not always associated with negative characteristics: improved sporting and spatial abilities also been found 10
  • 11. AO2 issues and debates • Gender bias evident as most research done on males (animals and humans) whereas it is known that there are differences between the genders in androgens • Also cultural bias as most research conducted in western countries 11
  • 12. AO2 debates • Reductionist to just consider role of biochemistry alone • Also need to consider genetic factors and brain structure • Eg. Phineas Gage suffered brain injury and showed heightened levels of aggression • Also need to consider the contribution of environmental factors such as situational cues, temperature, noise, overcrowding, and the role of learning 12
  • 13. AO2 application • Clearly a very important & useful area of biopsychological research and theory as aggression associated with many anti-social phenomena in society, eg. numerous forms of crime, violence • If the role of biochemistry can be understood it can perhaps be treated or managed • Although there would be ethical issues associated with giving people drugs simply to alleviate aggression (ie. for social control) , or male castration, even if it may be in the interests of multiple parties • Could perhaps be treated more ethically through diet (tryptophan) and exercise 13