The document discusses nasal drug delivery and strategies to increase nasal drug absorption. Some key points: - Nasal drug delivery is safer than injectable routes as it avoids needles and has good patient compliance. About 2% of drugs are administered nasally. - The nasal cavity has regions with different cell types and permeability. Several strategies can increase nasal drug absorption including prodrugs, absorption enhancers, and mucoadhesive formulations. - Nasal formulations include gels, sprays, drops and particulate systems. Characteristics like drug properties, dosage volume, and viscosity impact absorption. Polymers like pluronics are used to prepare thermoreversible nasal gels.