This document provides 10 tips for optimizing MySQL database performance at the operating system level. The tips include using SSDs instead of HDDs for faster I/O, allocating large amounts of memory, avoiding swap space, keeping the MySQL version up to date, using file systems without barriers, configuring RAID cards for write-back caching, and leveraging huge pages. Overall, the tips aim to improve I/O speeds and memory usage to enhance MySQL query processing performance.