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Multiplication of Matrices
 and its application in
         biology
Introduction
• Matrices are rectangular arrays with entries from an
  arbitrary field. An m × n (read "m by n") matrix is thus an array (aik)
  where i changes from 1 through m whereas k ranges
  from 1 through n. More explicitly,
  a11 a12 a13 ... a1n
  a21 a22 a23 ... a2n
  a31 a32 a33 ... a3n
  ...
  am1 am2 am3 ... amn
  which has m rows and n columns.
• In mathematics, matrix multiplication is a binary operation that
  takes a pair of matrices, and produces another matrix.
• Note: Multiplication of two matrices can only be carried out if the
  number of columns of the first matrix is equal to the number of
  rows of the second matrix.
How to carry out multiplication
         in matrices
             1. Consider two matrices A and B, as
                shown in the figure. Let the product
                matrix be C.
             2. We can obtain the first term of the
                matrix by the following operation:
                                          C1= (A1 x B1) + (A2
                x B3).
             3. We can obtain the other terms of the
                product matrix in a similar manner.
                               C2 = (A1 x B2) + (A2 x B4)
                               C3 = (A3 x B1) + (A4 x B3)
                               C4 = (A3 x B2) + (A4 x B4)
             4. In other cases, if the first matrix is of the
                order (m x n) and the second matrix is of
                the order (n x p), then the resultant
                matrix will be of the order (m x p).
Example
• Find out the product of the following matrix:
      A= 1 2 3                    B= 0 1 2
            1 0 0                        4 6 0
            4 1 2                        1 0 3
     The first term will equal to
           = (1 x 0) + (2 x 4) + (3 x 1)
           =8+3
           = 11
Properties of Matrix
          Multiplication
1. Matrix multiplication is not commutative in
   nature               i.e. AB ≠ BA
2. It is associative in nature
                        i.e. A(BC) = (AB)C

3. It is distributive over matrix multiplication
                        i.e. A(B+C) = AB + BC
                            (A+ C)B = AB + BC
4. Scalar multiplication commutes with matrix
   multiplication.
            λ(AB) = (λA)B
            (AB)λ = A(Bλ)
     where λ is a scalar.
5. For matrix transpose
            (AB)T = BTAT
     where T denotes transpose( the interchanging of
   row i with column i in a matrix).
6. For a square matrix A
            AI = IA = A
            where I is an identity matrix of same
   matrix.
Applications of Matrix Multiplication
              in Biology



1. Due to recent progress of DNA microarray
   technology, a large number of gene
   expression profile data are being produced.
   Matrix multiplication is used to analyze gene
   expression in computational molecular
   biology. Matrix multiplication is used in this
   technology to create simple algorithms.
2. In the circulatory system,
   the red blood cells are
   constantly being
   destroyed and replaced.
   Since they carry oxygen
   throughout the body,
   their numbers are fixed.
   We can use matrix
   multiplication to find out
   the level of red blood
   corpuscles in a person.
3. Matrix multiplication is used to
   find the frequency of sickle cell
   allele of the gene for hemoglobin
   causes red blood cells to
   collapse. Individuals with
   heterozygous genes for sickle cell
   develop immunity against
   malaria, but individuals
   homozygous for this gene tend
   to die at an early age. Matrix
   multiplication can be used to
   find out the frequency of
   occurrence of this gene in
   individuals living in a certain
   area and to calculate the
   possibility of this disease
   happening in a progeny of a
   family.
• Human populations have
  been increasing at a nearly
  exponential rate over the last
  couple of thousand years.
  Matrix multiplication is used
  for calculating population
  expansion of a species, not
  just human beings, over a
  period of time, provided it
  grows at a constant rate. This
  can help monitor the
  population of an endangered
  or over-populated species.
Bibliography
•   www.googleimages.com
•   www.biology301.com
•   www.wikipedia.com
•   NCERT maths for class 12th- part I
•   Engineering maths by V. P. Mishra
Thank
You

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Multiplication of matrices and its application in biology

  • 1. Multiplication of Matrices and its application in biology
  • 2. Introduction • Matrices are rectangular arrays with entries from an arbitrary field. An m × n (read "m by n") matrix is thus an array (aik) where i changes from 1 through m whereas k ranges from 1 through n. More explicitly, a11 a12 a13 ... a1n a21 a22 a23 ... a2n a31 a32 a33 ... a3n ... am1 am2 am3 ... amn which has m rows and n columns. • In mathematics, matrix multiplication is a binary operation that takes a pair of matrices, and produces another matrix. • Note: Multiplication of two matrices can only be carried out if the number of columns of the first matrix is equal to the number of rows of the second matrix.
  • 3. How to carry out multiplication in matrices 1. Consider two matrices A and B, as shown in the figure. Let the product matrix be C. 2. We can obtain the first term of the matrix by the following operation: C1= (A1 x B1) + (A2 x B3). 3. We can obtain the other terms of the product matrix in a similar manner. C2 = (A1 x B2) + (A2 x B4) C3 = (A3 x B1) + (A4 x B3) C4 = (A3 x B2) + (A4 x B4) 4. In other cases, if the first matrix is of the order (m x n) and the second matrix is of the order (n x p), then the resultant matrix will be of the order (m x p).
  • 4. Example • Find out the product of the following matrix: A= 1 2 3 B= 0 1 2 1 0 0 4 6 0 4 1 2 1 0 3 The first term will equal to = (1 x 0) + (2 x 4) + (3 x 1) =8+3 = 11
  • 5. Properties of Matrix Multiplication 1. Matrix multiplication is not commutative in nature i.e. AB ≠ BA 2. It is associative in nature i.e. A(BC) = (AB)C 3. It is distributive over matrix multiplication i.e. A(B+C) = AB + BC (A+ C)B = AB + BC
  • 6. 4. Scalar multiplication commutes with matrix multiplication. λ(AB) = (λA)B (AB)λ = A(Bλ) where λ is a scalar. 5. For matrix transpose (AB)T = BTAT where T denotes transpose( the interchanging of row i with column i in a matrix). 6. For a square matrix A AI = IA = A where I is an identity matrix of same matrix.
  • 7. Applications of Matrix Multiplication in Biology 1. Due to recent progress of DNA microarray technology, a large number of gene expression profile data are being produced. Matrix multiplication is used to analyze gene expression in computational molecular biology. Matrix multiplication is used in this technology to create simple algorithms.
  • 8. 2. In the circulatory system, the red blood cells are constantly being destroyed and replaced. Since they carry oxygen throughout the body, their numbers are fixed. We can use matrix multiplication to find out the level of red blood corpuscles in a person.
  • 9. 3. Matrix multiplication is used to find the frequency of sickle cell allele of the gene for hemoglobin causes red blood cells to collapse. Individuals with heterozygous genes for sickle cell develop immunity against malaria, but individuals homozygous for this gene tend to die at an early age. Matrix multiplication can be used to find out the frequency of occurrence of this gene in individuals living in a certain area and to calculate the possibility of this disease happening in a progeny of a family.
  • 10. • Human populations have been increasing at a nearly exponential rate over the last couple of thousand years. Matrix multiplication is used for calculating population expansion of a species, not just human beings, over a period of time, provided it grows at a constant rate. This can help monitor the population of an endangered or over-populated species.
  • 11. Bibliography • www.googleimages.com • www.biology301.com • www.wikipedia.com • NCERT maths for class 12th- part I • Engineering maths by V. P. Mishra