This study used the SWAT model to simulate runoff and soil loss in the 1491 km2 Sarrath river catchment in Tunisia to identify high erosion risk areas. The model performed well in calibration and validation. Simulation results showed high correlation between runoff and sediment yield. Only 10% of the catchment area had high to very high erosion rates, contributing 70% of sediment. The highest erosion sub-catchments were identified to prioritize conservation measures. The SWAT model proved effective for assessing spatial variability of erosion risk across the catchment and aiding management planning.