1. A mole is a unit used to quantify an amount of substance and refers to 6.022x10^23 elementary entities, whether atoms, molecules, ions or other particles. 2. The mass of one mole of a substance can be calculated from its relative atomic/molecular mass. For example, one mole of carbon has a mass of 12g while one mole of oxygen has a mass of 32g. 3. Moles allow for stoichiometric calculations to determine amounts of reactants and products in chemical reactions and for calculating molar concentrations in solutions.