This document discusses tools and methods for conducting surveys of maize lethal necrosis (MLN). Standardized paper and electronic survey forms have been developed to collect data on MLN occurrence and spread in farmer fields and commercial seed. The surveys aim to understand MLN distribution, monitor changes over time, and inform breeding programs. GPS is used to geo-reference survey locations and sample collection sites. Electronic surveys on smartphones and tablets offer advantages like automatic data transfer and integration of GPS, photos, and barcode scanning compared to traditional paper forms requiring manual data entry. The standardized surveys are meant to facilitate collection of representative and comparable MLN data across countries and years.
Software for Ebola Emergency Response - NasctechDenis Pankratov
Software Platform for Field Health Operations
- Ensures multiple Ebola (EVD) protocols are enforced via smartphone checklists
- Automates activities and delivers operational efficiency to field teams
-Enables the Operations Center to coordinate multiple teams across countries and regions, to establish Environmental Control
- Automate procedures for conducting contact follow-up
- Ensures multiple Ebola (EVD) protocols are enforced via smartphone checklists
- Automates activities and delivers operational efficiency to field teams
- Enables the Operations Center to coordinate multiple teams across countries and regions via cloud and smartphones
- Automate procedures for conducting contact follow-up
At Social Cops, we disrupt the traditional data collection methods by empowering local youth and our non profit partners with smart phones thereby making the process cost-effective, faster, and efficient. Please find attached a detailed note on our work.
Our methods of data collection & monitoring are expected to reduce 50% time & more than 100% of costs for data collection processes. We work with partners such as the Digital Empowerment Foundation, RoSES and corporate CSR wings such as Hindustan Unilever to create impact in the grassroots through smart data.
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Invited talk at the national institute of astronomy and geophysics - Helwan on Wed. 21 October 2014 on Data is the new oil: Big data, data mining and bio - inspiring techniques
Spatial distribution of disease has always been one of the major concern in public health. Epidemiology, as a science, use different kinds of the information system to study data related to health-related states and events. GIS has been a newer technology for the health system of Nepal.
Software for Ebola Emergency Response - NasctechDenis Pankratov
Software Platform for Field Health Operations
- Ensures multiple Ebola (EVD) protocols are enforced via smartphone checklists
- Automates activities and delivers operational efficiency to field teams
-Enables the Operations Center to coordinate multiple teams across countries and regions, to establish Environmental Control
- Automate procedures for conducting contact follow-up
- Ensures multiple Ebola (EVD) protocols are enforced via smartphone checklists
- Automates activities and delivers operational efficiency to field teams
- Enables the Operations Center to coordinate multiple teams across countries and regions via cloud and smartphones
- Automate procedures for conducting contact follow-up
At Social Cops, we disrupt the traditional data collection methods by empowering local youth and our non profit partners with smart phones thereby making the process cost-effective, faster, and efficient. Please find attached a detailed note on our work.
Our methods of data collection & monitoring are expected to reduce 50% time & more than 100% of costs for data collection processes. We work with partners such as the Digital Empowerment Foundation, RoSES and corporate CSR wings such as Hindustan Unilever to create impact in the grassroots through smart data.
Smart Urban Planning Support through Web Data Science on Open and Enterprise ...Gloria Re Calegari
Prediction of expensive datasets starting from a set of cheap heterogeneous information sources in smart city scenarios.
Prediction of the population and land use of Milano starting from data about Points Of Interest and phone activity.
Data are the new oil: Big data, data mining and bio - inspiring techniquesAboul Ella Hassanien
Invited talk at the national institute of astronomy and geophysics - Helwan on Wed. 21 October 2014 on Data are the new oil: Big data, data mining and bio - inspiring techniques
Data is the new oil: Big data, data mining and bio - inspiring techniquesAboul Ella Hassanien
Invited talk at the national institute of astronomy and geophysics - Helwan on Wed. 21 October 2014 on Data is the new oil: Big data, data mining and bio - inspiring techniques
Spatial distribution of disease has always been one of the major concern in public health. Epidemiology, as a science, use different kinds of the information system to study data related to health-related states and events. GIS has been a newer technology for the health system of Nepal.
MLN status, Disease diagnosis and Management Kitale, Kenya 23rd June 2022.pptxSuresh, L.M
MLN diagnosis and disease management training is given to NPPO's across in ESA to help them for understanding MLN disease. This also helps them for disease diagnosis and produce disease free seeds and manage the disease. Thus it helps for good food security. Recently the training wasprovided. This shall help a large audians
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In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
PRESENTATION ABOUT PRINCIPLE OF COSMATIC EVALUATION
Mln surveys – forms and tools dave hodson and suresh l m
1. MLN Surveys – Forms and Tools
Dr. Suresh, L.M.
CIMMYT – Sub Saharan Africa
Dave Hodson
CIMMYT-Ethiopia
d.hodson@cigar.org
MLN workshop, CIMMYT Kenya, Kitale 8-9th April, 2017
2. Why do we need field surveys?
• Understand what is happening in farmer fields
• Which diseases are present
• When and where diseases are occurring + spread
over time
• Collect samples to understand pathogen changes –
inform breeding programs
• Monitor changes over time
• Detect hot-spots of disease occurrence
• Basis for informing control and mitigation
3. Undertaking MLN Surveys
• Standardized survey protocols and tools developed
– please use them!
• Try to get representative coverage of the main crop
areas (use standard routes / cover similar areas in
different years)
• Collect representative samples as part of the survey
• Record accurate data, process samples and data
immediately after completing the survey
4. Enabling Tools & Technologies:
survey + sampling
Traditional New Options
• Smartphone / tablets (GPS, Camera, Electronic Form, Barcode scanner)
•Automatic data transfer
Standardized geo-referenced field surveys across countries
Field to database now possible in near real-time
• GPS + Paper forms
• Manual data entry
5. Paper Forms + GPS 1
• Standardized Forms (draft)
• 1. FIELD Survey
• Used in farmer fields / seed
production fields / maize
trials + LEAF samples
• Key components:
• FIELD Survey
– Geo-referenced (GPS)
– Basic site data
– MLN + other diseases
– Insects
– LEAF Samples
– AgriStrip results
– Basic Farm information
6. Paper Forms + GPS 2
• 2. SEED Survey
• Used at Agro-dealers + commercial seed
samples
• Key components:
• SEED Survey
– Geo-referenced (GPS)
– Basic Agro-dealer data
– Commercial seed sample data
7. Survey Data Entry
• If using Paper forms:
– Use the standard .XLS templates for MLN FIELD & MLN SEED Surveys
– Return data to national focal point (check and forward to CIMMYT [for Dbase entry])
• If using Electronic Surveys – Data entry is automatic!
– Data secured. ONLY returned to country national focal point / submitter (xls + map until
full data management system operational)
8. GPS Basics
ACCURACY
•Basic Units – Location. Typically +/- 5-10 m
•(elevation worse – +/- 3-4%?)
NOTE: Units work 24 hours a day, anywhere in
the world and in all weather. BUT, must have a
clear view of sky – so not indoors, in dense
forest, or next to buildings etc
No cost to receive satellite signals
11. 3. Record Location “Mark a Waypoint”
Key Information:
Latitude (in decimal degrees)
Longitude (in decimal degrees)
Elevation (meters)
12. New Tools – Electronic Surveys
• Android: Smartphone or Tablet
• FIELD + SEED Survey developed (replicate
paper forms
• Advantages:
– Electronic data form (+quality control)
– Integrated GPS
– Camera (geo-ref photos)
– Barcode scanner
– Automatic transfer of data to core database
• Disadvantages:
– Lack of familiarity
– Small screen size (phones)
– Connectivity for data transmission
– (Field visibility + GPS connections)
BIG ADVANTAGES FOR MLN SURVEYS!
14. MLN FIELD Survey Page 1
Text Entry
Pick List (names of countries)
Date / Calendar
Text Entry
GPS Location button
15. MLN FIELD Survey – QR Code Scanning
• ScSc
D4QjulZ92. Opens Camera
3. Scan QR code
4. Auto-fill QR code in survey form
1. Get Barcode button
16. Conclusion
• Standardized draft MLN survey forms developed – FIELD & SEED
Surveys
• Available in paper + electronic format (Android tablets / smartphones)
• Geo-referencing a key component of both formats (essential for data
management and value addition / modelling work)
• Use of electronic forms offer big advantages for MLN (e.g., automatic
QR code scanning for lots of samples)