This lecture provides an overview of early Mesopotamian civilization between the Tigris and Euphrates Rivers. It discusses the geography and climate of the region, known as the Fertile Crescent, which allowed for the development of irrigation-based agriculture and urban settlements. Sumerians were the first to settle the region around 5000 BC, developing dams, canals and cities like Uruk and Ur. Writing and other innovations emerged as cities grew in size and complexity between 3500-3000 BC. Social classes and kingship developed, with temples becoming important religious and administrative centers marked by ziggurats.