Meiosis is a type of cell division that produces gametes, such as sperm and egg cells, with half the number of chromosomes as the original parent cell. It involves two rounds of division and results in four daughter cells each with only one copy of each chromosome type. This ensures genetic variation between gametes and allows for recombination of genes from both parents during fertilization. Key events in meiosis include homologous chromosome pairing, crossing over, and independent assortment of homologs, which contribute to genetic diversity in offspring.
Activity 4 Understanding the basics of meiosisMitosis and mei.docxcoubroughcosta
Activity 4: Understanding the basics of meiosis
Mitosis and meiosis both lead to new daughter cells, but meiosis sets up organisms for sexual
reproduction. Meiosis produces cells (sperm and egg in humans) with only one set of chromosomes so that when fertilization occurs, it results in a new cell with two sets of chromosomes (one from the egg and one from the sperm). This is how there is genetic recombination of DNA resulting in unique individuals.
Before we talk about what can go wrong in meiosis, you need to be clear about the process itself and how genetic recombination in particular occurs. To this end, complete the following set of questions.
Questions
1. In the following diagram, draw what a cell with 1 chromosome would look like in the stages of meiosis. Prophase 1 is filled in for you and includes replicated homologous chromosomes; the black replicated chromosome is from the reproducing male’s mom and the grey replicated chromosome is from dad.
2. In your diagram from question 1:
a. How many tetrads are formed? _______________
b. How many chromosomes are in the sperm? _______________
3. In what stage(s) of meiosis:
a. Are tetrads formed? ________________________________
b. Does crossing over occur? ________________________________
c. Do the chromosomes move to the poles? ________________________________
d. Do replicated chromosomes separate? ________________________________
e. Does the cytoplasm divide? ________________________________
4. What processes in meiosis result in genetically unique daughter cells? When do these processes occur? (Note: There are two main processes; discuss both).
5. Compare and contrast meiosis with mitosis to complete the following table.
Table 2. Comparison of key characteristics between meiosis and mitosis.
Characteristics
Mitosis
Meiosis
Type of organisms it occurs in
# of chromosomes in human parent cell
Number of times chromosomes replicate
Number of cell divisions
Crossing over occurs? (Y/N)
Type of daughter cells produced
Number of daughter cells produced
Daughter cells identical to parent cell? (Y/N)
Daughter cells are: 1n or 2n?
# of chromosomes in human daughter cells
Activity 3: Chromosomes in mitosis and meiosis
In the nucleus of the cell are the chromosomes that are composed of the hereditary material DNA. In every somatic (body) cell of a human there are 46 chromosomes. Each species may have a different number of chromosomes than another species.
Since each somatic cell of an organism contains the same number of chromosomes, there must be a duplication of material before the nucleus divides during mitosis. In each somatic cell, there are two sets of chromosomes; this is referred to as the 2n (diploid) number, in which n means number of chromosomes. In humans, 2n = 46 chromosomes.
In each gamete (sex) cell, there is only one set of chromosomes; this is referred to as the 1n (haploid) number. In humans, 1n = 23 chromosomes. This means the.
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
Activity 4 Understanding the basics of meiosisMitosis and mei.docxcoubroughcosta
Activity 4: Understanding the basics of meiosis
Mitosis and meiosis both lead to new daughter cells, but meiosis sets up organisms for sexual
reproduction. Meiosis produces cells (sperm and egg in humans) with only one set of chromosomes so that when fertilization occurs, it results in a new cell with two sets of chromosomes (one from the egg and one from the sperm). This is how there is genetic recombination of DNA resulting in unique individuals.
Before we talk about what can go wrong in meiosis, you need to be clear about the process itself and how genetic recombination in particular occurs. To this end, complete the following set of questions.
Questions
1. In the following diagram, draw what a cell with 1 chromosome would look like in the stages of meiosis. Prophase 1 is filled in for you and includes replicated homologous chromosomes; the black replicated chromosome is from the reproducing male’s mom and the grey replicated chromosome is from dad.
2. In your diagram from question 1:
a. How many tetrads are formed? _______________
b. How many chromosomes are in the sperm? _______________
3. In what stage(s) of meiosis:
a. Are tetrads formed? ________________________________
b. Does crossing over occur? ________________________________
c. Do the chromosomes move to the poles? ________________________________
d. Do replicated chromosomes separate? ________________________________
e. Does the cytoplasm divide? ________________________________
4. What processes in meiosis result in genetically unique daughter cells? When do these processes occur? (Note: There are two main processes; discuss both).
5. Compare and contrast meiosis with mitosis to complete the following table.
Table 2. Comparison of key characteristics between meiosis and mitosis.
Characteristics
Mitosis
Meiosis
Type of organisms it occurs in
# of chromosomes in human parent cell
Number of times chromosomes replicate
Number of cell divisions
Crossing over occurs? (Y/N)
Type of daughter cells produced
Number of daughter cells produced
Daughter cells identical to parent cell? (Y/N)
Daughter cells are: 1n or 2n?
# of chromosomes in human daughter cells
Activity 3: Chromosomes in mitosis and meiosis
In the nucleus of the cell are the chromosomes that are composed of the hereditary material DNA. In every somatic (body) cell of a human there are 46 chromosomes. Each species may have a different number of chromosomes than another species.
Since each somatic cell of an organism contains the same number of chromosomes, there must be a duplication of material before the nucleus divides during mitosis. In each somatic cell, there are two sets of chromosomes; this is referred to as the 2n (diploid) number, in which n means number of chromosomes. In humans, 2n = 46 chromosomes.
In each gamete (sex) cell, there is only one set of chromosomes; this is referred to as the 1n (haploid) number. In humans, 1n = 23 chromosomes. This means the.
This slide is special for master students (MIBS & MIFB) in UUM. Also useful for readers who are interested in the topic of contemporary Islamic banking.
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2. Meiosis
Type of cell division
One germ cell makes 4 gametes
with ½ the # of chrom.
Occurs only in germ cells in gonads
○ testes /ovaries
Occurs in flowers
○ ovary and anther
4. This shows how only one single sperm gets to penetrate the
egg, releasing its nucleus of 23 chromosomes to merge with
the nucleus of the egg and its 23 chromosomes.
5. Homologous
Chromosomes
Pair of chrom. similar in shape , size, and types of genes.
Each locus (location of the gene) in same position on chrom.
Humans have 23 pairs of homologues
Housefly – 6 prs
Chicken – 39 prs
Apple – 17 prs
Dog – 39 prs
Cat – 19 prs
This is a karyotype
(an image of an organism’s
chromosomes)
This is a karyotype of a
normal human male
7. Prophase I
Longest and most complex phase (90%).
Chromosomes condense.
Synapsis - a process: when hom. chrom.
come together, pair up, form a tetrad.
9. Prophase I - Crossing Over
Crossing over may
occur in the tetrad:
between nonsister
chromatids, ends
break and reattach
10. Crossing Over - Provides Variation
nonsister chromatids
Chiasma: site of
crossing over
variation
Tetrad
11. Metaphase I
Shortest phase; paired homologues align.
INDEPENDENT ASSORTMENT occurs
pairs of homologues line up independently of other pairs’
orientation toward the poles -- random. Adds variation.
12. Anaphase I
Homologous chromosomes separate
towards the poles (Tetrads separate)
Sister chromatids remain attached
13. Telophase I
Each pole now has haploid set of chromosomes
(however – still doubled).
Cytokinesis occurs: two haploid daughter cells
formed.
14. Meiosis II
No interphase II
( no more DNA replication)
Remember: Meiosis II is similar to mitosis
Prophase II / Metaphase II
Anaphase II
15. Telophase II
Same as telophase in mitosis.
Nuclei form.
Cytokinesis occurs (2nd time).
Four haploid daughter cells produced (chromosomes now
back to single condition).
gametes ~ sperm or egg; ovule or pollen grain
16.
17.
18. Gamete Formation in Animals
Diff. bet. male and female gametes.
Male: spermatogenesis
all 4 develop into sperm cells.
Female: oogenesis
cytokinesis in meiosis is uneven.
most of cytoplasm goes into 1 of the 4 meiotic products
(forms large egg cell)
3 other cells are small “polar bodies”, break down (extra
chrom. lost).
19. Spermatogenesis
2n = 46
human
germ cell in
testes
diploid (2n)
n=23
Still doubled
chromosomes
n=23
Still doubled
chromosomes
meiosis I
n=23
n=23
n=23
n=23
sperm
haploid (n)
meiosis II
20. Oogenesis
2n = 46
human germ cell
in ovary
diploid (2n)
n=23
Still doubled
n=23
Still doubled
meiosis I
23
23
23
Ovum
n=23
Polar
Bodies
meiosis II
21. Mitosis vs Meiosis
Mitosis
Body (somatic cells)
2 daughter cells made
(identical)
Each w/ same # & kind
of chrom. as parent cell
1 division process
1 cytokinesis
No synapsis or
crossing over
Are diploid (2n)
Meiosis
Germ cells of gonads
4 gamete cells made
(all different)
Each w/ ½ chrom. # as
parent cell
2 divisions
2 cytokineses events
Synapsis &
crossing over occurs
in Prophase 1
Are haploid (n)
22. Chromosome numbers:
However many
“types” of
chromosomes an
organism has, that
number is the “n”
number of
chromosomes it has.
Body cells
(somatic cells)
therefore have a
“2n” # (diploid)
Gametes have
“n” # (haploid)
For humans,
2n = 46
n = 23
23. Nondisjunction
When the tetrad (in Anaphase I) or
the sister chromatids (in Anaphase II)
do not separate, creating an abnormal #
of chrom. to occur in the gametes.
Lethal most of the time