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MeiosisMeiosis
Review of MitosisReview of Mitosis
 Why do cells go through mitosis?Why do cells go through mitosis?
 To make new cells for growth and repairTo make new cells for growth and repair
 Remember the cells are identical to the parent (cloned)Remember the cells are identical to the parent (cloned)
 They areThey are diploiddiploid- have two sets of- have two sets of homologoushomologous
(matching) chromosomes (46)(matching) chromosomes (46)
 Prophase, Metaphase, Anaphase, TelophaseProphase, Metaphase, Anaphase, Telophase
What is Meiosis?What is Meiosis?
 Meiosis creates sex cellsMeiosis creates sex cells
((gametesgametes))
 Each resulting cells isEach resulting cells is
genetically different from thegenetically different from the
parent.parent.
 Why would this beWhy would this be
necessary?necessary?
 Meiosis results in 4Meiosis results in 4 haploidhaploid
cells- only 1 set ofcells- only 1 set of
chromosomes or 23chromosomes or 23
Meiosis leads to genetic variationMeiosis leads to genetic variation
 Meiosis creates 4 cells that are a different mix of yourMeiosis creates 4 cells that are a different mix of your
parents’parents’ genes.genes.
 Why would this be beneficial?Why would this be beneficial?
Can we seeCan we see
Genes?Genes?
KaryotypeKaryotype--
Picture of organismPicture of organism’s’s
ChromosomesChromosomes
Human Has 23 pairsHuman Has 23 pairs
2323RDRD
Pair is thePair is the
sex chromosomesex chromosome
What is the sex of thisWhat is the sex of this
Individual??Individual??
Process of MeiosisProcess of Meiosis
Meiosis results in a egg or spermMeiosis results in a egg or sperm
 There are 2 parts:There are 2 parts:
 Meiosis IMeiosis I
 Meiosis IIMeiosis II
Meiosis IMeiosis I
• Prophase IProphase I
– Proteins causeProteins cause homologoushomologous chromosomes to stick togetherchromosomes to stick together
• 4 chromatids (tetrads)4 chromatids (tetrads)
– Tetrads attach to spindleTetrads attach to spindle
– Genetic info is exchanged (Genetic info is exchanged (crossing overcrossing over))
• Metaphase IMetaphase I
– Tetrads move to middle of cell and line upTetrads move to middle of cell and line up
• Anaphase IAnaphase I
– Homologous chromosomes separateHomologous chromosomes separate
– 2 chromosomes move toward opposite poles2 chromosomes move toward opposite poles
 Telophase ITelophase I
 Chromosomes arrive at polesChromosomes arrive at poles
 Cytokinesis occurs resulting in two haploid daughter cellsCytokinesis occurs resulting in two haploid daughter cells
But it doesnBut it doesn’t end here. . .’t end here. . .
Meiosis IIMeiosis II
 Prophase IIProphase II
 Spindle forms in haploid daughter cellSpindle forms in haploid daughter cell
 Moves chromosomes to middle of cellMoves chromosomes to middle of cell
 Metaphase IIMetaphase II
 Chromosomes line up in middle of cellChromosomes line up in middle of cell
• Anaphase IIAnaphase II
– Sister chromatids separateSister chromatids separate
– Move to opposite polesMove to opposite poles
• Telophase IITelophase II
– Chromatids (individualChromatids (individual
chromosomes) arrive at poleschromosomes) arrive at poles
– Cytokinesis splits cellsCytokinesis splits cells
End Result. .End Result. . .. 4 HAPLOID DAUGHTER CELLS4 HAPLOID DAUGHTER CELLS
ReviewReview
1. Define1. Define ASEXUAL REPRODUCTIONASEXUAL REPRODUCTION
– is the production of Offspring from ONE PARENT.is the production of Offspring from ONE PARENT.
2. What is the result of Asexual Reproduction?2. What is the result of Asexual Reproduction?
-Two genetically identical daughter cells-Two genetically identical daughter cells
3. Are the results of Mitosis3. Are the results of Mitosis HaploidHaploid oror diploid?diploid?
- Diploid- Diploid
4. What does4. What does diploiddiploid mean?mean?
-cell with two homologous sets of chromosomes-cell with two homologous sets of chromosomes
5. What is5. What is homologoushomologous??
-matching set of chromosomes in a diploid cell.-matching set of chromosomes in a diploid cell.
6. What does Asexual reproduction involve? Mitosis or Meiosis.6. What does Asexual reproduction involve? Mitosis or Meiosis.
-Mitosis-Mitosis
7. In unicellular organisms, such as bacteria, how are new7. In unicellular organisms, such as bacteria, how are new
organisms created?organisms created?
-MITOSIS-MITOSIS..
8.8. SEXUAL REPRODUCTIONSEXUAL REPRODUCTION is the production of offspringis the production of offspring
through which method mitosis or meiosis?through which method mitosis or meiosis?
-Meiosis-Meiosis
9. What cells are involved in sexual reproduction?9. What cells are involved in sexual reproduction?
-sex cells (-sex cells (egg and sperm)egg and sperm)
10. MEIOSIS AND SEXUAL REPRODUCTION RESULTS IN How10. MEIOSIS AND SEXUAL REPRODUCTION RESULTS IN How
many cells?many cells?
--44 Haploid daughter cellsHaploid daughter cells
11. What is meant by11. What is meant by haploidhaploid??
- Cell with a single set of chromosomes- Cell with a single set of chromosomes
Law of IndependentLaw of Independent
AssortmentAssortment All genes are inheritedAll genes are inherited independentlyindependently
 Having one gene does not mean you willHaving one gene does not mean you will
automatically inherit another.automatically inherit another.
 Ex: If you have blond hair, what color will yourEx: If you have blond hair, what color will your
eyes be?eyes be?
 They could be brown, blue or green.They could be brown, blue or green.
 Hair color and eye color are inheritedHair color and eye color are inherited
independently of each other.independently of each other.
Meiosis IncreasesMeiosis Increases
VariationVariationRandom AssortmentRandom Assortment - different- different
chromosome combinations inchromosome combinations in
gametes contributes to geneticgametes contributes to genetic
variationvariation
Crossing OverCrossing Over – exchange of genetic– exchange of genetic
material between homologousmaterial between homologous
chromosomeschromosomes
 Segments of chromatids can beSegments of chromatids can be
exchanged at many sitesexchanged at many sites
 Single chromosome contains new comboSingle chromosome contains new combo
of genetic info from each parentof genetic info from each parent
 Result. .Result. . . Genetic Recombination. Genetic Recombination
But what happens when thisBut what happens when this
messes up?messes up?
 Sometimes homologous chromosomes fail to separateSometimes homologous chromosomes fail to separate
properly – RESULT…properly – RESULT…
 NondisjunctionNondisjunction
 What does this look like?What does this look like?
 Trisomy 21 – Down syndromeTrisomy 21 – Down syndrome
 Monosomy 23 – female with only one X chromosome =Monosomy 23 – female with only one X chromosome =
Turner syndrome= X0Turner syndrome= X0
TrisomyTrisomy 2121
 Down SyndromeDown Syndrome
 Affects 1 out of every 700 children in USAffects 1 out of every 700 children in US
 Abnormal facial featuresAbnormal facial features
 ShortnessShortness
 Heart defectsHeart defects
 Impaired immune systemImpaired immune system
 Mental disabilityMental disability
Monosomy 23Monosomy 23
Turner syndromeTurner syndrome
Affects 1 in 2500 girlsAffects 1 in 2500 girls
 Swollen hands and feetSwollen hands and feet
 Wide and webbed neckWide and webbed neck
 Broad, flat chest shaped like a shieldBroad, flat chest shaped like a shield
 Drooping eyelidsDrooping eyelids
 Dry eyesDry eyes
 InfertilityInfertility
 Short heightShort height
Meiosis

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Meiosis

  • 2. Review of MitosisReview of Mitosis  Why do cells go through mitosis?Why do cells go through mitosis?  To make new cells for growth and repairTo make new cells for growth and repair  Remember the cells are identical to the parent (cloned)Remember the cells are identical to the parent (cloned)  They areThey are diploiddiploid- have two sets of- have two sets of homologoushomologous (matching) chromosomes (46)(matching) chromosomes (46)  Prophase, Metaphase, Anaphase, TelophaseProphase, Metaphase, Anaphase, Telophase
  • 3. What is Meiosis?What is Meiosis?  Meiosis creates sex cellsMeiosis creates sex cells ((gametesgametes))  Each resulting cells isEach resulting cells is genetically different from thegenetically different from the parent.parent.  Why would this beWhy would this be necessary?necessary?  Meiosis results in 4Meiosis results in 4 haploidhaploid cells- only 1 set ofcells- only 1 set of chromosomes or 23chromosomes or 23
  • 4.
  • 5. Meiosis leads to genetic variationMeiosis leads to genetic variation  Meiosis creates 4 cells that are a different mix of yourMeiosis creates 4 cells that are a different mix of your parents’parents’ genes.genes.  Why would this be beneficial?Why would this be beneficial?
  • 6. Can we seeCan we see Genes?Genes? KaryotypeKaryotype-- Picture of organismPicture of organism’s’s ChromosomesChromosomes Human Has 23 pairsHuman Has 23 pairs 2323RDRD Pair is thePair is the sex chromosomesex chromosome What is the sex of thisWhat is the sex of this Individual??Individual??
  • 7. Process of MeiosisProcess of Meiosis Meiosis results in a egg or spermMeiosis results in a egg or sperm  There are 2 parts:There are 2 parts:  Meiosis IMeiosis I  Meiosis IIMeiosis II
  • 8. Meiosis IMeiosis I • Prophase IProphase I – Proteins causeProteins cause homologoushomologous chromosomes to stick togetherchromosomes to stick together • 4 chromatids (tetrads)4 chromatids (tetrads) – Tetrads attach to spindleTetrads attach to spindle – Genetic info is exchanged (Genetic info is exchanged (crossing overcrossing over))
  • 9.
  • 10. • Metaphase IMetaphase I – Tetrads move to middle of cell and line upTetrads move to middle of cell and line up • Anaphase IAnaphase I – Homologous chromosomes separateHomologous chromosomes separate – 2 chromosomes move toward opposite poles2 chromosomes move toward opposite poles
  • 11.  Telophase ITelophase I  Chromosomes arrive at polesChromosomes arrive at poles  Cytokinesis occurs resulting in two haploid daughter cellsCytokinesis occurs resulting in two haploid daughter cells But it doesnBut it doesn’t end here. . .’t end here. . .
  • 12.
  • 13. Meiosis IIMeiosis II  Prophase IIProphase II  Spindle forms in haploid daughter cellSpindle forms in haploid daughter cell  Moves chromosomes to middle of cellMoves chromosomes to middle of cell  Metaphase IIMetaphase II  Chromosomes line up in middle of cellChromosomes line up in middle of cell
  • 14. • Anaphase IIAnaphase II – Sister chromatids separateSister chromatids separate – Move to opposite polesMove to opposite poles • Telophase IITelophase II – Chromatids (individualChromatids (individual chromosomes) arrive at poleschromosomes) arrive at poles – Cytokinesis splits cellsCytokinesis splits cells End Result. .End Result. . .. 4 HAPLOID DAUGHTER CELLS4 HAPLOID DAUGHTER CELLS
  • 15.
  • 16. ReviewReview 1. Define1. Define ASEXUAL REPRODUCTIONASEXUAL REPRODUCTION – is the production of Offspring from ONE PARENT.is the production of Offspring from ONE PARENT. 2. What is the result of Asexual Reproduction?2. What is the result of Asexual Reproduction? -Two genetically identical daughter cells-Two genetically identical daughter cells 3. Are the results of Mitosis3. Are the results of Mitosis HaploidHaploid oror diploid?diploid? - Diploid- Diploid 4. What does4. What does diploiddiploid mean?mean? -cell with two homologous sets of chromosomes-cell with two homologous sets of chromosomes 5. What is5. What is homologoushomologous?? -matching set of chromosomes in a diploid cell.-matching set of chromosomes in a diploid cell. 6. What does Asexual reproduction involve? Mitosis or Meiosis.6. What does Asexual reproduction involve? Mitosis or Meiosis. -Mitosis-Mitosis
  • 17. 7. In unicellular organisms, such as bacteria, how are new7. In unicellular organisms, such as bacteria, how are new organisms created?organisms created? -MITOSIS-MITOSIS.. 8.8. SEXUAL REPRODUCTIONSEXUAL REPRODUCTION is the production of offspringis the production of offspring through which method mitosis or meiosis?through which method mitosis or meiosis? -Meiosis-Meiosis 9. What cells are involved in sexual reproduction?9. What cells are involved in sexual reproduction? -sex cells (-sex cells (egg and sperm)egg and sperm) 10. MEIOSIS AND SEXUAL REPRODUCTION RESULTS IN How10. MEIOSIS AND SEXUAL REPRODUCTION RESULTS IN How many cells?many cells? --44 Haploid daughter cellsHaploid daughter cells 11. What is meant by11. What is meant by haploidhaploid?? - Cell with a single set of chromosomes- Cell with a single set of chromosomes
  • 18.
  • 19. Law of IndependentLaw of Independent AssortmentAssortment All genes are inheritedAll genes are inherited independentlyindependently  Having one gene does not mean you willHaving one gene does not mean you will automatically inherit another.automatically inherit another.  Ex: If you have blond hair, what color will yourEx: If you have blond hair, what color will your eyes be?eyes be?  They could be brown, blue or green.They could be brown, blue or green.  Hair color and eye color are inheritedHair color and eye color are inherited independently of each other.independently of each other.
  • 20. Meiosis IncreasesMeiosis Increases VariationVariationRandom AssortmentRandom Assortment - different- different chromosome combinations inchromosome combinations in gametes contributes to geneticgametes contributes to genetic variationvariation Crossing OverCrossing Over – exchange of genetic– exchange of genetic material between homologousmaterial between homologous chromosomeschromosomes  Segments of chromatids can beSegments of chromatids can be exchanged at many sitesexchanged at many sites  Single chromosome contains new comboSingle chromosome contains new combo of genetic info from each parentof genetic info from each parent  Result. .Result. . . Genetic Recombination. Genetic Recombination
  • 21. But what happens when thisBut what happens when this messes up?messes up?  Sometimes homologous chromosomes fail to separateSometimes homologous chromosomes fail to separate properly – RESULT…properly – RESULT…  NondisjunctionNondisjunction  What does this look like?What does this look like?  Trisomy 21 – Down syndromeTrisomy 21 – Down syndrome  Monosomy 23 – female with only one X chromosome =Monosomy 23 – female with only one X chromosome = Turner syndrome= X0Turner syndrome= X0
  • 22.
  • 23.
  • 24. TrisomyTrisomy 2121  Down SyndromeDown Syndrome  Affects 1 out of every 700 children in USAffects 1 out of every 700 children in US  Abnormal facial featuresAbnormal facial features  ShortnessShortness  Heart defectsHeart defects  Impaired immune systemImpaired immune system  Mental disabilityMental disability
  • 25.
  • 26. Monosomy 23Monosomy 23 Turner syndromeTurner syndrome Affects 1 in 2500 girlsAffects 1 in 2500 girls  Swollen hands and feetSwollen hands and feet  Wide and webbed neckWide and webbed neck  Broad, flat chest shaped like a shieldBroad, flat chest shaped like a shield  Drooping eyelidsDrooping eyelids  Dry eyesDry eyes  InfertilityInfertility  Short heightShort height