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Vitamins
Discovery
In 1910, the first vitamin complex was isolated by
Japanese scientist Umetaro Suzuki,
who succeeded in extracting
a water-soluble complex of micronutrients
from rice bran and named it
aberic acid.
In 1912 Polish biochemist
Casimir Funk isolated the same
complex of micronutrients and
proposed the complex be named
"vitamine“ .
The word “vitamin”
comes from the term
“ Vital amines”
Vitamins are required
to perform
specific cellular functions.
Many of the water-soluble vitamins
are precursors of
coenzymes for
the enzymes of
intermediary metabolism.
In contrast to the
water-soluble vitamins,
only vitamin K
has a coenzyme
function.
Definition of vitamin
“Vital amines”
Vitamins are chemically unrelated
organic compounds required
in the diet in small amounts to perform
specific biological functions that
can not be synthesized
in adequate quantities by humans
& therefore, must be supplied
by the diet.
Classification of the vitamins
Depending on the solubility
vitamins are classified into-
1. Water soluble vitamins
2. Fat soluble vitamins
Nine vitamins are classified as
water soluble.
Water soluble vitamins are
readily excreted
in the urine.
So, toxicity is rare.
But, deficiencies can occur
quickly.
Four vitamins (A, D, E, and K)
are fat soluble
They are released, absorbed,
and transported
(in chylomicrons) with
dietary fat.
“Fat soluble vitamins
are not
readily excreted
from the body.”
Significant quantities
are stored in
the liver and
adipose tissue.
Excessive consumption of
vitamin A and D
above the
“Dietary Reference Intake” level
can accumulate
in the body.
Classification of the vitamins
1. Water – soluble vitamins
a. B-Complex:
i. Energy releasing:
Thiamine (Vitamin B1)
Riboflavin (VitaminB2)
Niacin (Vitamin B3)
Pantothenic acid (Vitamin B5)
Biotin (Vitamin B7)
ii. Hematopoietic:
 Folic acid (B9)
 Vitamin B12
iii. Others:
Pyridoxine (Vitamin B6)
Pyridoxal
Pyridoxamine
a.Non B-Complex:
Ascorbic acid (Vitamin C)
2.Fat soluble vitamins
 Vitamin A (retinol,β- carotenes)
 Vitamin D (cholecalciferol)
 Vitamin K (phylloquinones,
menaquinones)
 Vitamin E (tocopherols)

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Medical Biochemistry | Food and Nutrition, Vitmins and Minerals: Introduction to Vitamins