Identifying information retrieval research for systematic reviews and other e...Patrice Chalon
Background:
To date, Cochrane has focused primarily on publishing systematic reviews of the effectiveness of healthcare interventions and subsequently reviews of diagnostic test accuracy. How to identify studies in these areas is well-described in The Cochrane Handbooks. Cochrane is considering extending its remit to evidence syntheses in other areas, such as economic evaluations, prognosis and qualitative research. Study identification has not yet received as much attention in these areas within Cochrane. Additionally, under MECIR (Methodological Expectations of Cochrane Intervention Reviews), if a Cochrane Review has specific eligibility criteria around study design to address adverse effects, economic issues or qualitative research questions, it is now mandatory that searches must be undertaken to address these issues. These areas, together with others, are covered in a new web resource, SuRe Info, produced by the Interest Sub-Group on Information Resources (IRG) of Health Technology Assessment international (HTAi).
Objective:
To present the SuRe Info resource.
Methods:
Information retrieval methods publications are identified by database searching. Publications meeting the SuRe Info inclusion criteria receive a structured abstract containing a brief critical appraisal prepared by one SuRe Info information specialist and checked by another. Key messages from the appraisals are summarized into topic-specific chapters.
Results:
SuRe Info is published as a section of the HTAi Vortal (www.sure-info.org). It has two parts:
1) chapters on general search methods common across all evidence syntheses and
2) chapters describing the methods to use when searching for specific aspects of evidence syntheses, such as adverse effects / safety and economic evaluations. Chapters summarize current research evidence with links to the structured abstracts / appraisals.
Conclusion:
SuRe Info is a new open-access web resource that provides research-based summaries relating to information retrieval for evidence synthesis including systematic reviews. It provides a valuable addition to the information provided in The Cochrane Handbooks.
This document summarizes a presentation about ensuring data quality in the PHIS+ consortium, which integrates clinical and administrative data across multiple children's hospitals for comparative effectiveness research. It describes the process of developing common data models, semantically mapping local data elements to standards, collecting data using a toolkit with validation, processing the data through a platform to standardize terminology and storage, and conducting various automated and manual checks for data quality issues. These included checks for missing or invalid data, relationships between test results and specimens/cultures, and study-specific assessments through chart review. The final database contained over 4.5 million records across various domains with standardized coding to support health services research.
State-Level Estimates from the NHIS Restricted Data: Analysis to support stat...soder145
The document discusses using restricted National Health Interview Survey (NHIS) data to produce state-level estimates for evaluating the Affordable Care Act (ACA). It notes that NHIS data can provide timely, state-representative information on health insurance coverage and utilization but state identifiers are restricted. The project aims to use a Census Research Data Center to merge public and restricted NHIS files, producing state-level estimates available through SHADAC's Data Center. This would help states monitor the impact of health reform over time.
Nurses use research and evidence-based practice to provide quality patient care. Evidence-based practice combines research findings with clinical expertise and patient preferences. The EBP process is similar to the Big6 information problem solving technique. Both involve defining questions, collecting and appraising evidence, and evaluating outcomes. The Connelly Library provides resources like Summon and CINAHL to help nurses conduct searches for evidence as part of the EBP process. Guides are also available for nursing, diseases, and evidence-based research.
1) The document discusses hospital librarianship and the Regina Qu'Appelle Health Region Health Sciences Library where the author works. It provides an overview of the library's services, collections, challenges, and the author's role.
2) The author conducted a research project surveying users about their use of Google for health information. The survey found that over 50% of users always use Google and lack skills to use it effectively for work information.
3) Based on the survey results, the author provides "Google instruction" classes to teach users how to search more effectively on Google and discusses limitations to promote evidence-based practice. The classes were well received by users seeking to learn search skills and find better
The document discusses substance use and recovery programs among college students. It provides statistics showing that 31 out of every 100 college students meet the criteria for a substance use disorder. Collegiate recovery programs aim to provide support for students in recovery from substance use disorders by offering mutual aid support groups, dedicated staff, and physical space for students to gather. They have been shown to help students achieve higher GPAs and graduation rates compared to those not in recovery programs.
The document summarizes statistics on substance use and substance use disorders among college students from a national survey. It finds that 31 students out of 22,000 at one college had a substance use disorder, with 6 having a substance dependency disorder and 24 engaging in illicit drug use. It then discusses collegiate recovery programs (CRPs) at various universities that provide support for students in recovery and are associated with higher GPAs, retention, and graduation rates compared to students who do not participate in recovery programs. CRPs aim to change campus culture and provide intrapersonal, interpersonal, and community support through mutual aid groups, dedicated staff, and dedicated physical spaces for students in recovery.
Identifying information retrieval research for systematic reviews and other e...Patrice Chalon
Background:
To date, Cochrane has focused primarily on publishing systematic reviews of the effectiveness of healthcare interventions and subsequently reviews of diagnostic test accuracy. How to identify studies in these areas is well-described in The Cochrane Handbooks. Cochrane is considering extending its remit to evidence syntheses in other areas, such as economic evaluations, prognosis and qualitative research. Study identification has not yet received as much attention in these areas within Cochrane. Additionally, under MECIR (Methodological Expectations of Cochrane Intervention Reviews), if a Cochrane Review has specific eligibility criteria around study design to address adverse effects, economic issues or qualitative research questions, it is now mandatory that searches must be undertaken to address these issues. These areas, together with others, are covered in a new web resource, SuRe Info, produced by the Interest Sub-Group on Information Resources (IRG) of Health Technology Assessment international (HTAi).
Objective:
To present the SuRe Info resource.
Methods:
Information retrieval methods publications are identified by database searching. Publications meeting the SuRe Info inclusion criteria receive a structured abstract containing a brief critical appraisal prepared by one SuRe Info information specialist and checked by another. Key messages from the appraisals are summarized into topic-specific chapters.
Results:
SuRe Info is published as a section of the HTAi Vortal (www.sure-info.org). It has two parts:
1) chapters on general search methods common across all evidence syntheses and
2) chapters describing the methods to use when searching for specific aspects of evidence syntheses, such as adverse effects / safety and economic evaluations. Chapters summarize current research evidence with links to the structured abstracts / appraisals.
Conclusion:
SuRe Info is a new open-access web resource that provides research-based summaries relating to information retrieval for evidence synthesis including systematic reviews. It provides a valuable addition to the information provided in The Cochrane Handbooks.
This document summarizes a presentation about ensuring data quality in the PHIS+ consortium, which integrates clinical and administrative data across multiple children's hospitals for comparative effectiveness research. It describes the process of developing common data models, semantically mapping local data elements to standards, collecting data using a toolkit with validation, processing the data through a platform to standardize terminology and storage, and conducting various automated and manual checks for data quality issues. These included checks for missing or invalid data, relationships between test results and specimens/cultures, and study-specific assessments through chart review. The final database contained over 4.5 million records across various domains with standardized coding to support health services research.
State-Level Estimates from the NHIS Restricted Data: Analysis to support stat...soder145
The document discusses using restricted National Health Interview Survey (NHIS) data to produce state-level estimates for evaluating the Affordable Care Act (ACA). It notes that NHIS data can provide timely, state-representative information on health insurance coverage and utilization but state identifiers are restricted. The project aims to use a Census Research Data Center to merge public and restricted NHIS files, producing state-level estimates available through SHADAC's Data Center. This would help states monitor the impact of health reform over time.
Nurses use research and evidence-based practice to provide quality patient care. Evidence-based practice combines research findings with clinical expertise and patient preferences. The EBP process is similar to the Big6 information problem solving technique. Both involve defining questions, collecting and appraising evidence, and evaluating outcomes. The Connelly Library provides resources like Summon and CINAHL to help nurses conduct searches for evidence as part of the EBP process. Guides are also available for nursing, diseases, and evidence-based research.
1) The document discusses hospital librarianship and the Regina Qu'Appelle Health Region Health Sciences Library where the author works. It provides an overview of the library's services, collections, challenges, and the author's role.
2) The author conducted a research project surveying users about their use of Google for health information. The survey found that over 50% of users always use Google and lack skills to use it effectively for work information.
3) Based on the survey results, the author provides "Google instruction" classes to teach users how to search more effectively on Google and discusses limitations to promote evidence-based practice. The classes were well received by users seeking to learn search skills and find better
The document discusses substance use and recovery programs among college students. It provides statistics showing that 31 out of every 100 college students meet the criteria for a substance use disorder. Collegiate recovery programs aim to provide support for students in recovery from substance use disorders by offering mutual aid support groups, dedicated staff, and physical space for students to gather. They have been shown to help students achieve higher GPAs and graduation rates compared to those not in recovery programs.
The document summarizes statistics on substance use and substance use disorders among college students from a national survey. It finds that 31 students out of 22,000 at one college had a substance use disorder, with 6 having a substance dependency disorder and 24 engaging in illicit drug use. It then discusses collegiate recovery programs (CRPs) at various universities that provide support for students in recovery and are associated with higher GPAs, retention, and graduation rates compared to students who do not participate in recovery programs. CRPs aim to change campus culture and provide intrapersonal, interpersonal, and community support through mutual aid groups, dedicated staff, and dedicated physical spaces for students in recovery.
This document outlines the process for selecting eligible studies for a systematic literature review. It describes the main stages as screening the search output, assessing studies for eligibility by examining full texts, and extracting relevant data from included studies. Key steps involve removing duplicates, having two reviewers independently screen studies and resolve discrepancies, retrieving full texts of potentially eligible studies, and making final inclusion decisions based on pre-specified criteria. Maintaining clear documentation of decisions is important for transparency and reproducibility.
Assessing searches in NICE Single Technology Appraisals: practice and checklistscharrlibrary
This study investigates the limitations of manufacturers' search methodologies as critiqued by the Evidence Review Groups (ERG) in published Single Technology Appraisal (STA) reports with the purpose of developing a checklist for Health Technology Assessment (HTA) practice.
Measuring competence: building an assessment tool for public health graduate ...Erin D. Foster
Presentation for the Pacific Northwest Region of the National Network of Libraries of Medicine "PNR Partners" webinar series in March 2016.
Link to webinar recording: https://www.youtube.com/watch?v=uaKc8Aa4Gko
Presentation by Prof Lisa Askie, ANZCTR, to the 'Unlocking value from publicly funded Clinical Research Data' workshop, cohosted by ARDC and CSIRO at ANU on 6 March 2019.
Speaker Presentation from U.S. News Healthcare of Tomorrow leadership summit, Nov. 1-3, 2017 in Washington, DC. Find out more about this forum at www.usnewshot.com.
The document discusses open access policies for research data at the World Agroforestry Centre (ICRAF). It provides an overview of ICRAF's policy which states that data should be made openly accessible within 12 months of collection or project milestone. The policy allows centers flexibility to determine what constitutes incomplete or low-value data. Common misconceptions about open access are addressed, and benefits of open data are discussed such as improved publications, transparency, and recognition for researchers. Guidelines are provided for implementing open data policies including using metadata standards and archiving data.
This document discusses updates being made to the eBIRT (electronic Biomedical Research Tool), an online database that connects researchers to resources across multiple institutions. It aims to improve searchability and organization. Currently, only providers can update entries and there is a lack of structure. Next steps include consulting users and providers to improve discovery of resources and strengthen relationships between institutions. The goal is to clarify institutional structures to help researchers find applicable resources more easily and potentially stimulate new research.
Alliance for Risk Assessment Dose Response Framework- Society for Risk Analys...Oliver Kroner
With improvements in our biological understating, computational power, and an ever-changing regulatory landscape, new methods for evaluating human health impact and risk are emerging. Since 2010, the Beyond Science & Decisions workshop series has provided a venue for testing, vetting, and improving novel risk assessment methods. With the collaboration of over 55 organizations representing government, industry, scientific societies, consultancies, and environmental NGOs, the series has now reviewed over 30 case studies illustrating such methods. The ARA Dose Response Framework includes these case studies and links to key guidance documents on a range of risk assessment issues. It was developed by panel members and workshop participants as a way to categorize and identify gaps in available methods, and to aid risk assessors in identifying useful tools for different problem formulations. It is intended as a tool to help guide the risk assessor in selecting an appropriate method(s) for addressing different issues related to hazard characterization and dose-response assessment, and to help the field of risk assessment identify gaps in methodology. This symposium will highlight several methods that have been presented as part of the workshop series, and then provide an interactive demonstration of the Dose Response Framework and how these methods fit within the framework. The session will then open for audience discussion on enhancements to the Framework.
1) The document summarizes a presentation about the impact of the NIH Public Access Policy, which requires researchers receiving NIH funding to submit copies of published research papers to PubMed Central.
2) A survey found that 83% of UCSF researchers were aware of the policy, 45% were required to comply in the last year, and most figured out compliance on their own. Interviews revealed that researchers saw benefits but concerns about publisher burdens.
3) While more time is needed to fully understand the policy's impact, initial findings suggest researchers' attitudes are positively impacted and benefits outweigh negatives.
Presentation by Dr Davina Ghersi, NHMRC, to the 'Unlocking value from publicly funded Clinical Research Data' workshop, cohosted by ARDC and CSIRO at ANU on 6 March 2019.
Data Management Lab: Data mapping exercise exampleIUPUI
Spring 2014 Data Management Lab: Session 1 Data mapping exercise example (more details at http://ulib.iupui.edu/digitalscholarship/dataservices/datamgmtlab)
What you will learn:
1. Build awareness of research data management issues associated with digital data.
2. Introduce methods to address common data management issues and facilitate data integrity.
3. Introduce institutional resources supporting effective data management methods.
4. Build proficiency in applying these methods.
5. Build strategic skills that enable attendees to solve new data management problems.
Clinical Data Management: Strategies for unregulated dataIUPUI
This document summarizes a presentation on clinical data management strategies for unregulated data. It discusses how regulations like HIPAA and ICH GCP have established standard practices for regulated clinical trials in areas like efficiency, safety, accuracy, and privacy. However, these standards can be burdensome and inflexible for unregulated data. The presentation therefore outlines good clinical data management practices from a 2011 document that focus on planning, documentation, stakeholder involvement, and producing report-ready output to enable efficient data collection, processing, and analysis. It emphasizes beginning with the end in mind and using standardized case report forms and data collection tools.
This document presents a PPT on the application of big data technologies in healthcare and biomedical research. Large amounts of data are generated in these sectors from techniques like genome sequencing and health records. Big data applications are useful for managing this patient data across clinical informatics, imaging, public health, and bioinformatics. Specifically, technologies like Hadoop have helped address challenges of storing and accessing vast amounts of clinical information for research. The PPT discusses how literature reviews demonstrate big data's efficacy in areas like cloud computing and clinical informatics data management.
Cognika's Trial XL uses machine learning to analyze clinical trial data and provide insights to improve trial operations. It profiles investigators and sites, evaluates criteria that impact recruitment and outcomes, and ranks investigators. Case studies showed it identified criteria impacting recruitment, better accrual estimates, and new investigators, helping reduce delays. Trial XL leverages all past learning, applies analytics to extract insights, and accelerates decision making for clinical trials.
Closing the Loop in Healthcare Analytics - Correlating Clinical and Administrative Systems with Research Efforts to Deliver Clinical Efficiency in Real Time
Ecosystem Assessments at the Local Scale - Dr. Claire Brown (UNEP-WCMC)ESD UNU-IAS
This document discusses ecosystem assessments at the local scale. It defines an ecosystem assessment as a critical evaluation of knowledge from various sources to address policy questions. Assessments involve analysis and synthesis by experts, focus on what is known and uncertain, and link ecosystems, services, and people. They engage stakeholders and produce reports. National and sub-national assessments are increasingly common. Assessments can develop evidence, highlight tradeoffs, examine futures, understand values, and engage stakeholders. Credibility, legitimacy and relevance are key to success, as is user engagement, communication, and flexibility. The TESSA toolkit supports assessments of ecosystem services at site scales.
Investigator-initiated clinical trials: a community perspectiveARDC
Presentation by Miranda Cumpston, ACTA, to the 'Unlocking value from publicly funded Clinical Research Data' workshop, cohosted by ARDC and CSIRO at ANU on 6 March 2019.
RDAP 16 Poster: Measuring adoption of Electronic Lab Notebooks and their impa...ASIS&T
This document discusses challenges in measuring adoption and impact of electronic lab notebooks (ELNs) for research data management. It provides background on ELN implementation at Cornell and Wisconsin universities and describes prior efforts to survey ELN users about data management practices. Specifically, it examines difficulties in defining and assessing concepts like data management and adoption, and getting user perspectives on the value of ELNs for record keeping, metadata capture, and archiving data over time. Input is sought on how to improve questions that evaluate the degree to which ELNs help with various data management needs and goals.
A FAIR Data Sharing Framework for Large-Scale Human Cancer ProteogenomicsBrett Tully
A FAIR Data Sharing Framework for Large-Scale Human Cancer Proteogenomics
Islam M1,2, Christiansen J3, Mahboob S4, Valova V4, Baker M4, Capes-Davis D4, Hains P4, Balleine R1,4, Zhong Q1,4, Reddel R1,4, Robinson P1,4, Tully B4
1 The University of Sydney, Camperdown, Sydney, NSW, 2050, Australia
2 Intersect, Level 13/50 Carrington St, Sydney, NSW, 2000, Australia
3 Queensland Cyber Infrastructure Foundation Ltd, Axon Building 47, University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia
4 Children’s Medical Research Institute, Westmead, NSW, 2145, Australia
Background
The ACRF International Centre for the Proteome of Cancer (ProCan) at Children’s Medical Research Institute (CMRI) is an “industrial scale” program specialising in small-sample proteomics analysis from human cancer tissue.
ProCan seeks to generate both a wide and deep analytics pipeline and requires an enabling data framework. The framework must accommodate initial analysis and proteomic profiling of a large number of tumor samples, along with the clinical and demographic information, subsequent multi-omics studies, and any previously recorded responses to treatment. The curated datasets will provide a valuable resource beyond their primary use and ProCan is committed to making its data accessible to collaborators and the wider scientific community.
Objectives
The objective of the project is to an establish efficient, reliable, secure and ethical data sharing and publication framework based on the best practice data sharing principles, such as the FAIR principle. The framework must address various challenges that stem from the scale and complexity of the program, and ProCan’s focus on human-derived data and associated challenges presented in sharing these data while maintaining the privacy of any research participants.
Method
The project adopted a requirements-driven methodology and engaged with a wide range of ProCan stakeholders nationally and internationally. Together, various industrial-scale proteomics data management and sharing scenarios were explored such that robust and ethical sharing of the data would be achieved.
Results
The project developed a data sharing framework based on the FAIR principle that currently forms the basis of ongoing implementation work within the ProCan program.
Issues Related to Gene Therapy Assignment - Virtual High School (VHS) - SBI4UMichael Taylor
After reviewing the issues and opinions posted by your peers and receiving
feedback from your teacher, write an opinion paper that will show you have
thoroughly researched and reflected on this issue. Be sure to choose a particular
disorder/disease to use as an example.
Below are a couple of links to sites that may help you in organizing your opinion
paper. If you have any questions, please contact your teacher.
Resources:
Writing a Science Paper
Writing an Opinion Essay
Note on Writing In Science
All information and relevant data are to be included in a logically sequenced
manner. In your writing, it is important to use appropriate writing style, tone, and
scientific terminology. Conduct your research using reliable, peerreviewed and
industry sources and ensure that sources listed in your reference list are directly related to information presented in your paper. Use the appropriate referencing
style for science to cite your sources. For more information, see the page titled
“References” in the Scientific Skills and Formatting module of the Introduction unit in your course.
Measuring National M&E System Strengthening in Nigeria: Application of the Mo...MEASURE Evaluation
This document summarizes a study that used the Most Significant Change technique to measure strengthening of Nigeria's national M&E system from 2007-2012. Key stakeholders identified several most significant changes, including the harmonization of indicators to improve reporting, improved data quality through training, states now analyzing and using data, and the evolution of paper-based information systems to an integrated electronic system. These most significant changes were then verified through interviews and workshops to understand how the M&E system in Nigeria was strengthened over that period.
The document summarizes research conducted by Rajeeb Das and Timothy Brophy at the University of Florida to better understand faculty engagement in assessment processes and identify opportunities for improvement. Through surveys of assessment coordinators, stakeholder interviews, and faculty focus groups, they identified that faculty value assessment when it is used for student and program improvement. However, influential factors like class size and disciplinary accreditation requirements, as well as misconceptions about reporting requirements, can impact engagement. Based on these findings, the researchers made recommendations like facilitating peer sharing of assessment practices and clarifying reporting guidelines to cultivate greater faculty involvement.
This document outlines the process for selecting eligible studies for a systematic literature review. It describes the main stages as screening the search output, assessing studies for eligibility by examining full texts, and extracting relevant data from included studies. Key steps involve removing duplicates, having two reviewers independently screen studies and resolve discrepancies, retrieving full texts of potentially eligible studies, and making final inclusion decisions based on pre-specified criteria. Maintaining clear documentation of decisions is important for transparency and reproducibility.
Assessing searches in NICE Single Technology Appraisals: practice and checklistscharrlibrary
This study investigates the limitations of manufacturers' search methodologies as critiqued by the Evidence Review Groups (ERG) in published Single Technology Appraisal (STA) reports with the purpose of developing a checklist for Health Technology Assessment (HTA) practice.
Measuring competence: building an assessment tool for public health graduate ...Erin D. Foster
Presentation for the Pacific Northwest Region of the National Network of Libraries of Medicine "PNR Partners" webinar series in March 2016.
Link to webinar recording: https://www.youtube.com/watch?v=uaKc8Aa4Gko
Presentation by Prof Lisa Askie, ANZCTR, to the 'Unlocking value from publicly funded Clinical Research Data' workshop, cohosted by ARDC and CSIRO at ANU on 6 March 2019.
Speaker Presentation from U.S. News Healthcare of Tomorrow leadership summit, Nov. 1-3, 2017 in Washington, DC. Find out more about this forum at www.usnewshot.com.
The document discusses open access policies for research data at the World Agroforestry Centre (ICRAF). It provides an overview of ICRAF's policy which states that data should be made openly accessible within 12 months of collection or project milestone. The policy allows centers flexibility to determine what constitutes incomplete or low-value data. Common misconceptions about open access are addressed, and benefits of open data are discussed such as improved publications, transparency, and recognition for researchers. Guidelines are provided for implementing open data policies including using metadata standards and archiving data.
This document discusses updates being made to the eBIRT (electronic Biomedical Research Tool), an online database that connects researchers to resources across multiple institutions. It aims to improve searchability and organization. Currently, only providers can update entries and there is a lack of structure. Next steps include consulting users and providers to improve discovery of resources and strengthen relationships between institutions. The goal is to clarify institutional structures to help researchers find applicable resources more easily and potentially stimulate new research.
Alliance for Risk Assessment Dose Response Framework- Society for Risk Analys...Oliver Kroner
With improvements in our biological understating, computational power, and an ever-changing regulatory landscape, new methods for evaluating human health impact and risk are emerging. Since 2010, the Beyond Science & Decisions workshop series has provided a venue for testing, vetting, and improving novel risk assessment methods. With the collaboration of over 55 organizations representing government, industry, scientific societies, consultancies, and environmental NGOs, the series has now reviewed over 30 case studies illustrating such methods. The ARA Dose Response Framework includes these case studies and links to key guidance documents on a range of risk assessment issues. It was developed by panel members and workshop participants as a way to categorize and identify gaps in available methods, and to aid risk assessors in identifying useful tools for different problem formulations. It is intended as a tool to help guide the risk assessor in selecting an appropriate method(s) for addressing different issues related to hazard characterization and dose-response assessment, and to help the field of risk assessment identify gaps in methodology. This symposium will highlight several methods that have been presented as part of the workshop series, and then provide an interactive demonstration of the Dose Response Framework and how these methods fit within the framework. The session will then open for audience discussion on enhancements to the Framework.
1) The document summarizes a presentation about the impact of the NIH Public Access Policy, which requires researchers receiving NIH funding to submit copies of published research papers to PubMed Central.
2) A survey found that 83% of UCSF researchers were aware of the policy, 45% were required to comply in the last year, and most figured out compliance on their own. Interviews revealed that researchers saw benefits but concerns about publisher burdens.
3) While more time is needed to fully understand the policy's impact, initial findings suggest researchers' attitudes are positively impacted and benefits outweigh negatives.
Presentation by Dr Davina Ghersi, NHMRC, to the 'Unlocking value from publicly funded Clinical Research Data' workshop, cohosted by ARDC and CSIRO at ANU on 6 March 2019.
Data Management Lab: Data mapping exercise exampleIUPUI
Spring 2014 Data Management Lab: Session 1 Data mapping exercise example (more details at http://ulib.iupui.edu/digitalscholarship/dataservices/datamgmtlab)
What you will learn:
1. Build awareness of research data management issues associated with digital data.
2. Introduce methods to address common data management issues and facilitate data integrity.
3. Introduce institutional resources supporting effective data management methods.
4. Build proficiency in applying these methods.
5. Build strategic skills that enable attendees to solve new data management problems.
Clinical Data Management: Strategies for unregulated dataIUPUI
This document summarizes a presentation on clinical data management strategies for unregulated data. It discusses how regulations like HIPAA and ICH GCP have established standard practices for regulated clinical trials in areas like efficiency, safety, accuracy, and privacy. However, these standards can be burdensome and inflexible for unregulated data. The presentation therefore outlines good clinical data management practices from a 2011 document that focus on planning, documentation, stakeholder involvement, and producing report-ready output to enable efficient data collection, processing, and analysis. It emphasizes beginning with the end in mind and using standardized case report forms and data collection tools.
This document presents a PPT on the application of big data technologies in healthcare and biomedical research. Large amounts of data are generated in these sectors from techniques like genome sequencing and health records. Big data applications are useful for managing this patient data across clinical informatics, imaging, public health, and bioinformatics. Specifically, technologies like Hadoop have helped address challenges of storing and accessing vast amounts of clinical information for research. The PPT discusses how literature reviews demonstrate big data's efficacy in areas like cloud computing and clinical informatics data management.
Cognika's Trial XL uses machine learning to analyze clinical trial data and provide insights to improve trial operations. It profiles investigators and sites, evaluates criteria that impact recruitment and outcomes, and ranks investigators. Case studies showed it identified criteria impacting recruitment, better accrual estimates, and new investigators, helping reduce delays. Trial XL leverages all past learning, applies analytics to extract insights, and accelerates decision making for clinical trials.
Closing the Loop in Healthcare Analytics - Correlating Clinical and Administrative Systems with Research Efforts to Deliver Clinical Efficiency in Real Time
Ecosystem Assessments at the Local Scale - Dr. Claire Brown (UNEP-WCMC)ESD UNU-IAS
This document discusses ecosystem assessments at the local scale. It defines an ecosystem assessment as a critical evaluation of knowledge from various sources to address policy questions. Assessments involve analysis and synthesis by experts, focus on what is known and uncertain, and link ecosystems, services, and people. They engage stakeholders and produce reports. National and sub-national assessments are increasingly common. Assessments can develop evidence, highlight tradeoffs, examine futures, understand values, and engage stakeholders. Credibility, legitimacy and relevance are key to success, as is user engagement, communication, and flexibility. The TESSA toolkit supports assessments of ecosystem services at site scales.
Investigator-initiated clinical trials: a community perspectiveARDC
Presentation by Miranda Cumpston, ACTA, to the 'Unlocking value from publicly funded Clinical Research Data' workshop, cohosted by ARDC and CSIRO at ANU on 6 March 2019.
RDAP 16 Poster: Measuring adoption of Electronic Lab Notebooks and their impa...ASIS&T
This document discusses challenges in measuring adoption and impact of electronic lab notebooks (ELNs) for research data management. It provides background on ELN implementation at Cornell and Wisconsin universities and describes prior efforts to survey ELN users about data management practices. Specifically, it examines difficulties in defining and assessing concepts like data management and adoption, and getting user perspectives on the value of ELNs for record keeping, metadata capture, and archiving data over time. Input is sought on how to improve questions that evaluate the degree to which ELNs help with various data management needs and goals.
A FAIR Data Sharing Framework for Large-Scale Human Cancer ProteogenomicsBrett Tully
A FAIR Data Sharing Framework for Large-Scale Human Cancer Proteogenomics
Islam M1,2, Christiansen J3, Mahboob S4, Valova V4, Baker M4, Capes-Davis D4, Hains P4, Balleine R1,4, Zhong Q1,4, Reddel R1,4, Robinson P1,4, Tully B4
1 The University of Sydney, Camperdown, Sydney, NSW, 2050, Australia
2 Intersect, Level 13/50 Carrington St, Sydney, NSW, 2000, Australia
3 Queensland Cyber Infrastructure Foundation Ltd, Axon Building 47, University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia
4 Children’s Medical Research Institute, Westmead, NSW, 2145, Australia
Background
The ACRF International Centre for the Proteome of Cancer (ProCan) at Children’s Medical Research Institute (CMRI) is an “industrial scale” program specialising in small-sample proteomics analysis from human cancer tissue.
ProCan seeks to generate both a wide and deep analytics pipeline and requires an enabling data framework. The framework must accommodate initial analysis and proteomic profiling of a large number of tumor samples, along with the clinical and demographic information, subsequent multi-omics studies, and any previously recorded responses to treatment. The curated datasets will provide a valuable resource beyond their primary use and ProCan is committed to making its data accessible to collaborators and the wider scientific community.
Objectives
The objective of the project is to an establish efficient, reliable, secure and ethical data sharing and publication framework based on the best practice data sharing principles, such as the FAIR principle. The framework must address various challenges that stem from the scale and complexity of the program, and ProCan’s focus on human-derived data and associated challenges presented in sharing these data while maintaining the privacy of any research participants.
Method
The project adopted a requirements-driven methodology and engaged with a wide range of ProCan stakeholders nationally and internationally. Together, various industrial-scale proteomics data management and sharing scenarios were explored such that robust and ethical sharing of the data would be achieved.
Results
The project developed a data sharing framework based on the FAIR principle that currently forms the basis of ongoing implementation work within the ProCan program.
Issues Related to Gene Therapy Assignment - Virtual High School (VHS) - SBI4UMichael Taylor
After reviewing the issues and opinions posted by your peers and receiving
feedback from your teacher, write an opinion paper that will show you have
thoroughly researched and reflected on this issue. Be sure to choose a particular
disorder/disease to use as an example.
Below are a couple of links to sites that may help you in organizing your opinion
paper. If you have any questions, please contact your teacher.
Resources:
Writing a Science Paper
Writing an Opinion Essay
Note on Writing In Science
All information and relevant data are to be included in a logically sequenced
manner. In your writing, it is important to use appropriate writing style, tone, and
scientific terminology. Conduct your research using reliable, peerreviewed and
industry sources and ensure that sources listed in your reference list are directly related to information presented in your paper. Use the appropriate referencing
style for science to cite your sources. For more information, see the page titled
“References” in the Scientific Skills and Formatting module of the Introduction unit in your course.
Measuring National M&E System Strengthening in Nigeria: Application of the Mo...MEASURE Evaluation
This document summarizes a study that used the Most Significant Change technique to measure strengthening of Nigeria's national M&E system from 2007-2012. Key stakeholders identified several most significant changes, including the harmonization of indicators to improve reporting, improved data quality through training, states now analyzing and using data, and the evolution of paper-based information systems to an integrated electronic system. These most significant changes were then verified through interviews and workshops to understand how the M&E system in Nigeria was strengthened over that period.
The document summarizes research conducted by Rajeeb Das and Timothy Brophy at the University of Florida to better understand faculty engagement in assessment processes and identify opportunities for improvement. Through surveys of assessment coordinators, stakeholder interviews, and faculty focus groups, they identified that faculty value assessment when it is used for student and program improvement. However, influential factors like class size and disciplinary accreditation requirements, as well as misconceptions about reporting requirements, can impact engagement. Based on these findings, the researchers made recommendations like facilitating peer sharing of assessment practices and clarifying reporting guidelines to cultivate greater faculty involvement.
In this webinar, Nick will discuss recent research on policy evaluation and the use of environmental evidence within the U.S. Environmental Protection Agency (USEPA).
Since the inception of the USEPA, considerable emphasis has been placed on the use of policy analysis tools that aim to prospectively inform environmental policy decisions, including cost-benefit analysis and risk assessment used for regulatory actions. However, compared to the amount of such ex ante analysis conducted at the USEPA before a decision is reached, relatively little evaluation of these same environmental policies is produced after implementation to inform future policy development or to modify existing policies.
This original research applies accountability theory and organizational learning literature in order to identify and explain unique institutional factors that affect USEPA evaluation supply to inform future efforts.
Through a series of mixed methods case studies, this research seeks to inform efforts aimed at improving the quality of environmental evidence within the USEPA—through evaluation and systematic reviews—in order to better inform decision-making and achieve desired environmental outcomes.
A basic introduction to rapid reviews, created for a graduate student workshop, March 2018, presented by PF Anderson from the University of Michigan. Includes links to more resources, standards and guidelines, tools, software, and more.
Talk given by Victoria Cannon of Ohio State University College of Medicine at MyKnowledgeMap's Innovation in Practice Assessment Conference, St George's University of London.
How to Realize Benefits from Data Management Maturity ModelsKingland
View individual use cases from a large B2B organization, mid-size financial institution, and a scientific data repository. See the plan and outcome from all case studies.
ANDS health and medical data webinar 9 May. Review of the National Statement ...ARDC
Presentation by Jeremy Kenner from NHMRC on the review of the National Statement on Ethical Conduct in Human Research. Given on 9 May 2017
Full Webinar: https://www.youtube.com/watch?v=eENTF3oVVdk&t=2s
Transcript: https://www.slideshare.net/AustralianNationalDataService/transcript-webinar9517healthandmedicalshortbites
Qualitative data analysis is often a tough job and many researchers find it difficult to get comprehensive presentation on the topic. This seminar is an attempt to fulfil that purpose.
What must be done to ehance capacity for health systems research?IDS
This presentation was written by Sara Bennett, Ligia Paina, Christine Kim, Irene Agyepong, Somsak Chunharas, Di McIntyre and Stefan Nachuk for the Global Symposium on Health Systems Research, November, 2010.
Increasing District Level Evidence-based Decision Making in Cote d'IvoireMEASURE Evaluation
This document summarizes efforts in Côte d'Ivoire to increase evidence-based decision making at the district level through strengthening health information systems and data use. A data demand and use intervention was implemented with 8 mutually reinforcing activities, including engaging data users, improving data quality and availability, building capacity in data use, and strengthening organizational infrastructure for data use. Evaluations found improvements in data quality, availability, and use at district and facility levels. Regional data review meetings were established to identify information needs and facilitate evidence-based decision making.
This presentation discusses strategies for providing evaluation-based policy advice when evidence is uncertain. It was presented at the Australasian Evaluation Society Conference in Canberra. The presentation [1] recommends triangulating evidence from multiple sources like surveys, interviews and administrative data. It also suggests [2] corroborating findings with external evidence and [3] theorizing possible outcomes and impacts. Finally, it advises [3] considering the potential impacts and costs of any policy changes based on weak evidence, as well as risks of change. The presentation aims to guide evaluation advice when evidence is limited.
How to Assess and Continuously Improve Maturity of Health Information Systems...MEASURE Evaluation
This document describes a new toolkit for assessing and continuously improving health information systems (HIS) to achieve better health outcomes. The toolkit includes:
1) A five-stage scale to measure the maturity of six HIS components, from emerging to optimized.
2) An assessment tool that maps the current and desired future stages to guide improvement planning. It is administered through key informant interviews and a stakeholder workshop.
3) The goal is to help countries strengthen their HIS through a collaborative, participatory process focused on setting priorities and tracking progress over time.
EcoZD research units: Bridges and barriers to integrative research approachesILRI
This document discusses eight EcoZD research units in Southeast Asia that aim to improve integrative research approaches. It identifies both bridges and barriers to transdisciplinary collaboration. Key barriers include hierarchical structures and rigid reporting processes, while bridges include expanding stakeholder participation, opening information sharing, and securing senior leadership buy-in for long-term collaborative projects. The document provides strategies for research units to implement new structures and incentives, change organizational culture, and mitigate hindering or harness enabling factors to move towards paradigm shifts and better EcoHealth outcomes.
The Data Maze: Navigating the Complexities of Data GovernanceHealth Catalyst
Most organizations struggle to turn their data into a strategic asset. Oftentimes they lack the data they need, and don’t trust the data they have. This results in a struggle to surface meaningful opportunities, quantify the value of those opportunities, and transform insight into action. In this webinar, your host Tom Burton shares strategies for improving data literacy, ensuring data quality, and expanding data utilization.
This interactive, “choose your own adventure” style experience, allowed attendees to discover how investing in a deliberate, principle-based strategy can help them navigate the complexities of data governance and maximize the value of data for outcomes improvement.
View the webinar and learn:
- Demonstrate how to unleash data at your organization with efforts across the improvement spectrum.
- Recognize how to sustain and spread improvements across your entire organization.
- Illustrate the importance of investing in analytics training and infrastructure to prepare for massive improvement in healthcare outcomes.
- Understand the 5 key stages of the Data Life Cycle.
- Demonstrate strategies to overcome the common challenges around data quality, data utilization, and data literacy.
- Show how a data governance framework can accelerate improvement in clinical, cost, and experience outcomes.
CLUSTER EVALUATION KEY TO UNLOCKING LEARNING AND IMPROVEMENTOrkestra
James Wilson, Orkestra's Research Director shares his work with regards to cluster policy, the Basque case and the need to evaluate to make steps forward on the development and work of the clusters.
Uses of ICT in evaluation. Role of ICT in evaluation process. How evaluation helps students, teachers and business people. Mathematical works like graphs, piechart are used in ict evaluation process.
Tracking participants after they complete a higher education program is important for evaluating the program's impact but can be time consuming. The document discusses several strategies that can be used to more efficiently track participants, including collecting initial contact information, searching social media and public databases, conducting online surveys, developing automated tracking systems, and leveraging information from colleagues. It emphasizes that a robust tracking system and exploring new technologies like big data analytics can help improve outcomes assessment, but proper protections for participant data and technical expertise are needed.
Dr. Charles Macias (Texas Children's Hospital) talks about the inception, challenges, and logistics of a large Research Network, the PEMCRC (Pediatric Emergency Medicine Collaborative Research Committee).
Similar to Marquez, Diana, Burns & McDonnell, EPA's IRIS Database: What Can We Expect in the Future, 2015 MECC Kansas City (20)
Brunetti, Rick, KDHE, Regional Air Issues Roundtable, MECC, 2016, Overland ParkKevin Perry
Rick Brunetti, Director of the Bureau of Air at the Kansas Department of Health and Environment, presented at the Midwest Environmental Compliance Conference on May 13, 2016. The presentation showed trends in ozone levels across Kansas, permitting activities for air construction and operating permits issued to industry, and highlighted the department's mission to protect and improve the health and environment of all Kansans.
Chavez, Nikki, iSi Environmental, Form R Tips and Trip Ups, MECC, 2016, Overl...Kevin Perry
This document provides an overview of Form R reporting requirements under the Toxic Release Inventory program. It discusses that Form R has several names but is also known as the Toxic Chemical Release Inventory. Facilities must file a Form R if they have 10 or more full-time employees, engage in applicable industrial activities involving toxic chemicals above threshold quantities, and are not eligible for any exemptions. Thresholds and reporting criteria vary based on whether a chemical is manufactured, processed, or otherwise used. The document provides guidance on calculating thresholds and determining reporting obligations. It also outlines resources for complying with Form R reporting.
Muth, Emily, OPPD, Environmental Compliance and Information Systems, MECC, 20...Kevin Perry
The document discusses environmental compliance and information systems at a utility company. It analyzes the company's current environmental management structure and makes recommendations. Key recommendations include conducting a formal risk assessment, establishing environmental objectives and targets, defining environmental roles and responsibilities, evaluating operational controls, and formalizing processes for managing corrective actions while leveraging existing systems. The implementation of improvements would focus first at the plant level.
Wanzenried, Brian, Gavilon, Strategic Planning for Environmental Staffing, ME...Kevin Perry
This document discusses strategic planning considerations for environmental staffing. It addresses factors to consider in determining staff size and organizational reporting structure. Regarding staff size, the document examines industry benchmarks, regulatory drivers that incentivize adequate staffing, and risks of understaffing. For reporting structure, it explores where environmental staff typically report and advantages of higher-level positioning, such as improved influence, recruitment, planning input, and regulatory perception. The goal is to strategically structure environmental resources based on an organization's needs and risks.
Meerian, Marcus, KDHE, Overview of Revisions to the UST Regulations, MECC, 20...Kevin Perry
The document summarizes new requirements for underground storage tanks (USTs) in the 2015 EPA regulation revisions. Key changes include mandatory operator training, secondary containment for new/replaced tanks and piping, periodic inspection and testing requirements for spill/overfill prevention and detection equipment, and removal of deferrals so emergency generator tanks and certain other previously exempt UST systems must now meet regulation standards. States with approved UST programs have until adopting the new federal standards for the requirements to take effect, while in unapproved states and Indian country the requirements take effect according to the regulation timelines.
Hieb, Wendy, IDNR, Hot Topics in NPDES Permitting, MECC, 2016, Overland ParkKevin Perry
This document summarizes hot topics in NPDES permitting in Iowa, including: updating water quality standards; renewing general permits 5 and 7; creating new general permits 8 and 9; implementing the Iowa Nutrient Reduction Strategy; addressing temperature limits and 316(b) cooling water intake requirements; and complying with new steam electric effluent guidelines. It provides details on permit inventories, rulemaking timelines, and challenges associated with implementing various permitting programs and regulatory requirements in Iowa.
Johnson, Susan, IDNR, Making Hazardous/Non-Hazardous Waste Determinations, ME...Kevin Perry
Susan Johnson presented on Iowa's Special Waste Authorization program which provides for the safe disposal of wastes that pose a threat to human health or the environment. The program requires generators to determine if their wastes are hazardous under RCRA regulations before disposing them. Examples of wastes that may require special authorization include paint booth waste, demolition debris, and contaminated soils. The presentation covered waste determination procedures, disposal standards like limits for toxic metals, and resources available to assist generators in properly managing their wastes.
Andracsek, Robynn, Burns & McDonnell, What Every EHS Staff should Know about ...Kevin Perry
This document discusses air dispersion modeling for environmental permitting. It provides an overview of the EPA-approved models for different types of areas and pollutants. It also summarizes key aspects of modeling including significance thresholds, modeling stages, averaging periods, sources, receptors, meteorological data requirements, and potential challenges. Common questions around stack height, downwash effects, and acceptable input tolerances are also addressed.
Funderburg, Lisa, Stinson Leonard Street, Compliance Tools Top Ten Tips When ...Kevin Perry
Funderburg Lisa Stinson Leonard Street Compliance Tools Top Ten Tips When Conducting an Audit MECC Kansas City 2016 May 11-13, 2016 Overland Park www.mecconference.com
Grice, Lisa, Ramboll, Corporate Sustainability Where the Rest of the Company ...Kevin Perry
Grice Lisa Ramboll Corporate Sustainability Where the Rest of the Company Fits From Strategy to Implementation MECC Kansas City May 11-13, 2016 Overland Park www.mecconference.com
Exploring low emissions development opportunities in food systemsCIFOR-ICRAF
Presented by Christopher Martius (CIFOR-ICRAF) at "Side event 60th sessions of the UNFCCC Subsidiary Bodies - Sustainable Bites: Innovating Low Emission Food Systems One Country at a Time" on 13 June 2024
A Comprehensive Guide on Cable Location Services Detections Method, Tools, an...Aussie Hydro-Vac Services
Explore Aussie Hydrovac's comprehensive cable location services, employing advanced tools like ground-penetrating radar and robotic CCTV crawlers for precise detection. Also offering aerial surveying solutions. Contact for reliable service in Australia.
POPE FRANCIS 2ND ENCYCLICAL "Laudato Si" is the second encyclical of Pope Fra...AdelinePdelaCruz
"Laudato Si" is the second encyclical of Pope Francis, released on May 24, 2015. Its title comes from the opening words of the encyclical in Latin, which mean "Praise Be to You." The document focuses on the theme of care for our common home, urging humanity to take action to address environmental degradation, climate change, and social inequality. Pope Francis calls for an integral ecology that considers the interconnectedness of environmental, social, economic, and spiritual dimensions.
The modification of an existing product or the formulation of a new product to fill a newly identified market niche or customer need are both examples of product development. This study generally developed and conducted the formulation of aramang baked products enriched with malunggay conducted by the researchers. Specifically, it answered the acceptability level in terms of taste, texture, flavor, odor, and color also the overall acceptability of enriched aramang baked products. The study used the frequency distribution for evaluators to determine the acceptability of enriched aramang baked products enriched with malunggay. As per sensory evaluation conducted by the researchers, it was proven that aramang baked products enriched with malunggay was acceptable in terms of Odor, Taste, Flavor, Color, and Texture. Based on the results of sensory evaluation of enriched aramang baked products proven that three (3) treatments were all highly acceptable in terms of variable Odor, Taste, Flavor, Color and Textures conducted by the researchers.
Emerging Earth Observation methods for monitoring sustainable food productionCIFOR-ICRAF
Presented by Daniela Requena Suarez, Helmholtz GeoResearch Center Potsdam (GFZ) at "Side event 60th sessions of the UNFCCC Subsidiary Bodies - Sustainable Bites: Innovating Low Emission Food Systems One Country at a Time" on 13 June 2024
Trichogramma spp. is an efficient egg parasitoids that potentially assist to manage the insect-pests from the field condition by parasiting the host eggs. To mass culture this egg parasitoids effectively, we need to culture another stored grain pest- Rice Meal Moth (Corcyra Cephalonica). After rearing this pest, the eggs of Corcyra will carry the potential Trichogramma spp., which is an Hymenopteran Wasp. The detailed Methodologies of rearing both Corcyra Cephalonica and Trichogramma spp. have described on this ppt.
Marquez, Diana, Burns & McDonnell, EPA's IRIS Database: What Can We Expect in the Future, 2015 MECC Kansas City
1. EPA’s IRIS Database:
What Can We Expect in the Future?
Diana Y. Marquez
dmarque@burnsmcd.com 816-822-3453
May 14, 2015 Midwest Environmental Conference
2. 2
2
What is IRIS? Why Do I Care?
►EPA’s Integrated Risk Information System
►Top Source of Toxicity Data
►Key Resource for Risk Assessment and
Risk-Based Cleanup Levels
3. 3
3
Why Change the Program?
►2011 NRC Recommendations
• Improve clarity of IRIS assessment
• Describe methods of the assessment
• Assess disciplinary structure of teams
• Standardize approach
Including/excluding studies
Evaluate strengths/weaknesses of critical studies
Rationale for studies used to calculate tox values
Integration of evidence
4. 4
4
What are the Changes?
► New document structure – Done
► Methods and Criteria Preamble – Done
► Improved Public Comment/Peer Review – Done
► Improved Stakeholder Engagement – Done
► Stopping Rules – Done
► Identifying/Selecting Studies – Done
► Approach to Evaluating Evidence – Done
► Integration of Evidence – In progress
► Needs Assessment – In progress