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EPA’s IRIS Database:
What Can We Expect in the Future?
Diana Y. Marquez
dmarque@burnsmcd.com 816-822-3453
May 14, 2015 Midwest Environmental Conference
2
2
What is IRIS? Why Do I Care?
►EPA’s Integrated Risk Information System
►Top Source of Toxicity Data
►Key Resource for Risk Assessment and
Risk-Based Cleanup Levels
3
3
Why Change the Program?
►2011 NRC Recommendations
• Improve clarity of IRIS assessment
• Describe methods of the assessment
• Assess disciplinary structure of teams
• Standardize approach
 Including/excluding studies
 Evaluate strengths/weaknesses of critical studies
 Rationale for studies used to calculate tox values
 Integration of evidence
4
4
What are the Changes?
► New document structure – Done
► Methods and Criteria Preamble – Done
► Improved Public Comment/Peer Review – Done
► Improved Stakeholder Engagement – Done
► Stopping Rules – Done
► Identifying/Selecting Studies – Done
► Approach to Evaluating Evidence – Done
► Integration of Evidence – In progress
► Needs Assessment – In progress
5
5
Questions?
►Diana Marquez
►816-822-3453
►dmarque@burnsmcd.com

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  • 1. EPA’s IRIS Database: What Can We Expect in the Future? Diana Y. Marquez dmarque@burnsmcd.com 816-822-3453 May 14, 2015 Midwest Environmental Conference
  • 2. 2 2 What is IRIS? Why Do I Care? ►EPA’s Integrated Risk Information System ►Top Source of Toxicity Data ►Key Resource for Risk Assessment and Risk-Based Cleanup Levels
  • 3. 3 3 Why Change the Program? ►2011 NRC Recommendations • Improve clarity of IRIS assessment • Describe methods of the assessment • Assess disciplinary structure of teams • Standardize approach  Including/excluding studies  Evaluate strengths/weaknesses of critical studies  Rationale for studies used to calculate tox values  Integration of evidence
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